Disturbances in selective information processing associated with the BDNF Val66Met polymorphism: Evidence from cognition, the P300 and fronto-hippocampal systems

Biological Psychology

Volumn 80, Issue 2, 2009, Pages 176-188

  Schofield, Peter R ^a,b,c   Williams, Leanne M ^d   Paul, Robert H ^e   Gatt, Justine M ^d   Brown, Kerri ^d   Luty, Agnes ^c   Cooper, Nicholas ^f   Grieve, Stuart ^f   Dobson Stone, Carol ^a,b,c   Morris, Charlotte ^f   Kuan, Stacey A ^d   Gordon, Evian ^d,f  

^a NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d WESTMEAD HOSPITAL   (Australia)

^e UNIVERSITY OF MISSOURI ST LOUIS   (United States)

^f Brain Resource Company   (Australia)

Author keywords

BDNF Val66Met; Brain derived neurotrophic factor; Cognition; Grey matter; Hippocampus; Neuroimaging; P300 event related potential

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; METHIONINE; VALINE;

ADULT; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; ATTENTION; BRAIN FUNCTION; COGNITION; CONTROLLED STUDY; EVENT RELATED POTENTIAL; FEMALE; FRONTAL LOBE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; GRAY MATTER; HERITABILITY; HIPPOCAMPUS; HOMOZYGOTE; HUMAN; MALE; MEMORY; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; PRIORITY JOURNAL; RECALL; SENSORIMOTOR FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STIMULUS RESPONSE; TASK PERFORMANCE; VERBAL COMMUNICATION;

ACOUSTIC STIMULATION; ADULT; ANALYSIS OF VARIANCE; AUTOMATIC DATA PROCESSING; BRAIN MAPPING; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHI-SQUARE DISTRIBUTION; COGNITION; COHORT STUDIES; EVENT-RELATED POTENTIALS, P300; FEMALE; FRONTAL LOBE; GENOTYPE; HIPPOCAMPUS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; METHIONINE; MIDDLE AGED; NEURAL PATHWAYS; NEUROPSYCHOLOGICAL TESTS; OXYGEN; POLYMORPHISM, GENETIC; REGRESSION ANALYSIS; VALINE; YOUNG ADULT;

EID: 59649093385     PISSN: 03010511     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsycho.2008.09.001     Document Type: Article

References (74)

1. Ashburner J., and Friston K.J. Voxel-based morphometry - the methods. Neuroimage 11 (2000) 805-821
2. Baddeley A., Emslie H., and Nimmo-Smith I. The Spot-the-Word test: a robust estimate of verbal intelligence based on lexical decision. The British Journal of Clinical Psychology 32 (1993) 55-65
3. Baguley I.J., Felmingham K.L., Lahz S., Gordan E., Lazzaro I., and Schotte D.E. Alcohol abuse and traumatic brain injury: effect on event-related potentials. Archives of Physical Medicine and Rehabilitation 78 (1997) 1248-1253
4. Benton A.L., and Hamsher K. Multilingual Aphasia Examination (1989), AJA Associates, Iowa City, Iowa
5. Bramon, McDonald E.C., Croft F.R.J., Landau S., Filbey F., Cruzelier J.H., Sham P.C., Frangou S., and Murray R.M. Is the P300 wave an endophenotype for schizophrenia? A meta-analysis and a family study. Neuroimage 27 (2005) 960-968
6. Brown K., Gordon E., Williams L.M., Bahramali H., Harris A.W.F., Gray J.A., et al. Misattribution of sensory input reflected in dysfunctional target: Non-target ERPs in schizophrenia. Psychological Medicine 30 (2000) 1443-1449
7. Bueller J.A., Aftab M., Sen S., Gomez-Hassan D., Burmeister M., and Zubieta J.K. BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects. Biological Psychiatry 59 (2006) 812-815
8. Chen Z.Y., Patel P.D., Sant G., Meng C.X., Teng K.K., Hempstead B.L., et al. Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. Journal of Neuroscience 24 (2004) 4401-4411
9. Clark C.R., Orr R.S., Wright E.K., and Weber D.L. Working memory updating to visual verbal stimuli: a high resolution ERP study. In: Koga Y., Nagata K., and Hirata K. (Eds). Brain Topography Today (1998), Elsevier, Tokyo 173-178
10. Clark C.R., Paul R.H., Williams L.M., Arns M., Fallahpour K., Handmer C., and Gordon E. Standardized assessment of cognitive functioning during development and aging using an automated touchscreen battery. Archives of Clinical Neuropsychology 21 (2006) 449-467
11. Crottaz-Herbette S., Lau K.M., Glover G.H., and Menon V. Hippocampal involvement in detection of deviant auditory and visual stimuli. Hippocampus 15 (2005) 132-139
12. Donchin E., and Coles M.G.H. Is the P300 component a manifestation of context updating?. The Behavioral and Brain Sciences 11 (1998) 357-374
13. Downar J., Crawley A.P., Mikulis D.J., and Davis K.D. A cortical network sensitive to stimulus salience in a neutral behavioral context across multiple sensory modalities. The Journal of Neurophysiology 87 1 (2002) 615-620
14. Duncan-Johnson C.C., and Donchin E. The P300 component of the event-related potential as an index of information processing. Biological Psychology 14 (1982) 1-52
15. Egan M.F., Kojima M., Callicott J.H., Goldberg T.E., Kolachana B.S., Bertolino A., et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112 (2003) 257-269
16. Felmingham K.L., Bryant R.A., Gordon E., and Kendall C. Event-related potentials in posttraumatic stress disorder: The role of numbing. Psychiatry Research 109 (2002) 171-179
17. Friedman W.J., and Greene L.A. Neurotrophin signaling via Trks and p75. Experimental Cell Research 253 (1999) 131-142
18. Friston K.J., Holmes A.P., Poline J.B., Price C.J., and Frith C.D. Detecting activations in PET and fMRI: levels of inference and power. NeuroImage 4 (1996) 223-235
19. Geffen G.M., Moar K.J., Hanlon A.P., Clark C.R., and Geffen L.B. Performance measures of 16- to 86-year-old males and females on the Auditory Verbal Learning test. The Clinical Neuropsychologist 4 (1990) 45-63
20. Golden C.J. Stroop Color and Word Test (1978), Stoelting Company, Wood Dale, IL
21. Gordon E. Integrative neuroscience and psychiatry. Neuropsychopharmacology 28 1 (2003) S2-S8
22. Gordon E. Integrative neuroscience in psychiatry: the role of a standardized database. Australasian Psychiatry 11 (2003) 156-163
23. Gordon E., Cooper N., Rennie C., Hermens D., and Williams L.M. Integrative neuroscience: the role of a standardized database. Clinical EEG and Neuroscience 36 (2005) 64-75
24. Gratton G., Coles M.G., and Donchin E. A new method for off-line removal of occular artifact. Electroencephalography and Clinical Neurophysiology 55 (1983) 468-484
25. Grieve S., Clark C.R., Williams L.M., and Gordon E. Limbic and paralimbic preservation with aging. Human Brain Mapping 25 (2005) 391-401
26. Halgren E., Squires N.K., Wilson C.L., Rohrbraugh J.W., Babb T.L., and Crandall P.H. Endogenous potentials generated in the human hippocampal formation and amygdala by infrequent events. Science 210 (1980) 803-805
27. Hall D., Dhilla A., Charalambous A., Gogos J.A., and Karayiorgou M. Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder. American Journal of Human Genetics 73 (2003) 370-376
28. Hariri A.R., and Weinberger D.R. Imaging genomics. British Medical Bulletin 65 (2003) 259-270
29. Hariri A.R., Goldberg T.E., Mattay V.S., Kolachana B.S., Callicott J.H., Egan M.F., et al. BDNF val66met polymorphism modulates memory-related hippocampal activity and predicts memory performance. Journal of Neuroscience 23 (2003) 6690-6694
30. Harris S.E., Fox H., Wright A.F., Hayward C., Starr J.M., Whalley L.J., et al. The brain-derived neurotrophic factor Val66Met polymorphism is associated with age-related change in reasoning skills. Molecular Psychiatry 11 (2006) 505-513
31. Heit G., Smith M.E., and Halgren E. Neuronal activity in the human medial temporal lobe during recognition memory. Brain 113 (1990) 1093-1112
32. Hesselbrock V., Begleiter H., Porjesz B., O'Connor S., and Bauer L. P300 event-related potential amplitude as an endophenotype of alcoholism-evidence from the collaborative study on the genetics of alcoholism. Journal of Biomedical Science 8 (2001) 77-81
33. Hickie I., Hadzi-Pavlovic D., Scott E., Davenport T., Koschera A., and Naismith S. SPHERE: a national depression project. Australasian Psychiatry 6 (1998) 248-250
34. Jonson Jr. R. Auditory and visual P300s in temporal lobectomy patients: evidence for modality-dependent generators. Psychophysiology 26 (1989) 633-650
35. Knight R.T. Contribution of human hippocampal region to novelty detection. Nature 383 (1996) 256-259
36. Kraiuhin C., Yiannikis C., Coyle S., Gordon E., Rennie C., Howson A., et al. The relationship between reaction time and latency of the P300 event-related potential in normal subjects and Alzheimer's disease. Clinical and Experimental Neurology 26 (1989) 80-88
37. Kroenke K., and Spitzer R.L. The PHQ-9: a new depression and diagnostic severity measure. Psychiatric Annals 32 (2002) 509-521
38. Kunugi H., Ueki A., Otsuka M., Isse K., Hirasawa H., Kato N., et al. A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease. Molecular Psychiatry 6 (2001) 83-86
39. Lagopoulos J., Clouston P., Barhamali H., Gordon E., Li W.M., Lesley J., et al. Late components of the event-related potentials and their topography in Parkinson's disease. Movement Disorders 13 (1998) 262-267
40. Landau P., Gordon E., Kraiuhin C., Sara G., Singer A., Zurynski Y., et al. The use of regional cerebral blood flow and the P300 event-related potential (ERP) in the diagnosis of dementia and depression. Australia New Zealand Journal of Medicine 18 (1998) 421-431
41. Lazzaro I., Anderson J., Gordon E., Clarke S., Leong J., and Meares R.A. Single trial variability within the P300 (250-500 ms) processing window in adolescents with attention deficit hyperactivity disorder. Psychiatry Research 73 (1997) 91-101
42. McCarthy G., Wood C.C., Williamson P.D., and Spencer D.D. Task-dependent field potentials in human hippocampal formation. Journal of Neuroscience 9 (1989) 4253-4260
43. McCarthy G., Luby M., Gore J., and Goldman-Rakic P. Infrequent events transiently activate human prefrontal and parietal cortex as measured by functional MRI. Journal of Neurophysiology 77 (1997) 1630-1634
44. Menon V., Ford J.M., Lim K.O., Glover G.H., and Pfefferbaum A. Combined event-related fMRI and EEG evidence for temporal-parietal cortex activation during target detection. NeuroReport 8 (1997) 3029-3037
45. Milner B. Memory and the medial temporal regions of the brain. In: Pribram K.H., and Broadbent D.E. (Eds). Biology of Memory (1970), Academic Press, New York
46. Momose Y., Murata M., Kobayashi K., Tachikawa M., Nakabayashi Y., Kanazawa I., et al. Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms. Annals of Neurology 51 (2002) 133-136
47. Neves-Pereira M., Mundo E., Muglia P., King N., Macciardi F., and Kennedy J.L. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. American Journal of Human Genetics 71 (2002) 651-655
48. O'Connor S.O., Morzorati S., Christian J.C., and Li T.-K. Heritable features of the auditory oddball event-related potential: peaks, latencies, morphology and topography. Electroencephalography and Clinical Neurophysiology 59 (1994) 238-248
49. Onofrj M., Fulgente T., Nobilio D., Malatesta G., Bazzano S., Colamartino P., and Gambi D. P3 recordings in patients with bilateral temporal lobe lesions. Neurology 42 (1992) 1762
50. Paul R.H., Lawrence J., Williams L.M., Clark C.R., Cooper N., and Gordon E. A standardized battery for computerized neurocognitive assessment: Methods and construct validity of the 'IntegNeuro™'. International Journal of Neuroscience 115 (2005) 1549-1567
51. Paul R.H., Gunstad J., Cooper N.J., Williams L.M., Clark R.C., Cohen R.A., Lawrence J.J., and Gordon G. Cross-cultural assessment of neuropsychological performance and electrical brain function measures: Additional validation of an international brain database. International Journal of Neuroscience 117 (2007) 549-568
52. Pezawas L., Verchinksi B.A., Mattay V.S., Callicott J.H., Kolachana B.S., Straub R.E., et al. The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. Journal of Neuroscience 10 (2004) 10099-10102
53. Polich J. Theoretical overview of P3a and P3b. In: Polich J. (Ed). Detection of Change: Event-Related Potential and fMRI Findings (2003), Kluwer Academic, Boston 83-98
54. Polich J., and Kok A. Cognitive and biological determinants of P300: an integrative review. Biological Psychology 41 (1995) 103-146
55. Poo M.M. Neurotrophins as synaptic modulators. Nature Review Neuroscience 2 (2001) 24-32
56. Reitan R.M. Validity of the Trail Making Test as an indicator of organic brain damage. Perceptual and Motor Skills 8 (1958) 271-276
57. Rennie C.J., Robinson P.A., and Wright J.J. Unified neurophysical model of EEG spectra and evoked potentials. Biological Cybernetics 86 (2002) 457-471
58. Ribases M., Gratacos M., Armengol L., de Cid R., Badia A., Jimenez L., et al. Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type. Molecular Psychiatry 8 (2003) 745-751
59. Riemenschneider M., Schwarz S., Wagenpfeil S., Diehl J., Muller U., Forstl H., et al. A polymorphism of the brain-derived neurotrophic factor (BDNF) is associated with Alzheimer's disease in patients lacking the Apolipoprotein E epsilon4 allele. Molecular Psychiatry 7 (2002) 782-785
60. Rugg M.D., Pickles C.D., Potter D.D., and Roberts R.C. Normal P300 following extensive damage to the left medial temporal lobe. Journal of Neurology, Neurosurgery, and Psychiatry 54 (1991) 217-222
61. Scheltens P., and Korf E.S. Contribution of neuroimaging in the diagnosis of Alzheimer's disease and other dementias. Current Opinion in Neurology 13 (2000) 391-396
62. Sen S., Nesse R.M., Stoltenberg S.F., Li S., Gleiberman L., Chakravarti A., et al. A BDNF coding variant is associated with NEO personality inventory domain neuroticism, a risk factor for depression. Neuropsychopharmacology 28 (2003) 397-401
63. Sklar P., Gabriel S.B., McInnis M.G., Bennett P., Lim Y.M., Tsan G., et al. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Molecular Psychiatry 7 (2002) 579-593
64. Soltani M., and Knight R.T. Neural origins of the P300. Critical Reviews in Neurobiology 14 (2000) 199-224
65. Szeszko P.R., Lipsky R., Mentschel C., Robinson D., Gunduz-Bruce H., Sevy S., et al. Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Molecular Psychiatry 10 (2005) 631-636
66. Tyler W.J., Alonso M., Bramham C.R., and Pozzo-Miller L.D. From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learning & Memory 9 (2001) 224-237
67. Ventriglia M., Bocchio Chiavetto L., Benussi L., Binetti G., Zanetti O., Riva M.A., et al. Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease. Molecular Psychiatry 7 (2002) 136-137
68. Verleger R. Event-related potentials and cognition: a critique of the context updating hypothesis and an alternative interpretation of P3. The Behavioral and Brain Sciences 11 (1998) 343-356
69. Walsh K.W. Understanding Brain Damage: A Primer of Neuropsychological Evaluation (1985), Churchill Livingstone, Edinborough pp. 234-237
70. Williams L.M., Bahramali H., Hemsley D.R., Harris A.W.F., Brown K., and Gordon E. Electrodermal responsivity distinguishes ERP activity and symptom profile in schizophrenia. Schizophrenia Research 59 (2003) 115-125
71. Williams L.M., Simms E., Clark C.R., Paul R., Rowe D., and Gordon E. The reproducibility of a standardized and integrated neurophysiological and neuropsychological test battery. International Journal of Neuroscience 115 (2005) 1605-1630
72. Williams L.M., Felmingham K., Kemp A.H., Rennie C., Brown K.J., Bryant R.A., and Gordon E. Mapping frontal-limbic correlates of orienting to change detection. NeuroReport 18 (2007) 197-200
73. Worsley K.J., Marrett S., Neelin P., Vandal A.C., Friston K.J., and Evans A.C. A unified statistical approach for determining significant signals in images of cerebral activation. Human Brain Mapping 4 (1996) 58-73
74. Yoshiura T., Zhong J., Shibata D., Kwok W., Shrier D.A., and Numaguchi Y. Functional MRI study of auditory and visual oddball tasks. Neuroreport 10 8 (1999) 1683-1688