Presence of eosinophils in nasal secretion during acute respiratory tract infection in young children predicts subsequent wheezing within two months

Allergology International

Volumn 57, Issue 4, 2008, Pages 359-365

  Shinohara, Miwa ^a,b,c   Wakiguchi, Hiroshi ^a   Saito, Hirohisa ^c   Matsumoto, Kenji ^c  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b Noichi Central Hospital   (Japan)

^c NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

Eosinophils; Nasal secretion; Respiratory tract infection; Wheezing; Young children

Indexed keywords

ARTICLE; ASTHMA; ATOPIC DERMATITIS; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; EOSINOPHIL; FAMILY HISTORY; FEMALE; FOOD ALLERGY; HIGH RISK PATIENT; HUMAN; HUMAN CELL; INFANT; MALE; NOSE SECRETION; PATHOGENESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPIRATORY TRACT INFECTION; RHINORRHEA; WHEEZING;

EID: 59549098301     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.O-08-544     Document Type: Article

References (50)

1. Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med 1995;332:133-8.
2. Stocks J. Respiratory physiology during early life. Monaldi Arch Chest Dis 1999;54:358-64.
3. Oh JW. Respiratory viral infections and early asthma in childhood. Allergol Int 2006;55:369-72.
4. Stein RT, Holberg CJ, Morgan WJ et al. Peak flow variability, methacholine responsiveness and atopy as markers for detecting different wheezing phenotypes in childhood. Thorax 1997;52:946-52.
5. Shay DK, Holman RC, Newman RD, Liu LL, Stout JW, Anderson LJ. Bronchiolitis-associated hospitalizations among US children, 1980-1996. JAMA 1999;282:1440-6.
6. Anderson LJ, Heilman CA, Protective and disease-enhancing immune responses to respiratory syncytial virus. J Infect Dis 1995; 171:1-7.
7. Duff AL, Pomeranz ES, Gelber LE et al. Risk factors for acute wheezing in infants and children: viruses, passive smoke, and IgE antibodies to inhalant allergens. Pediatrics 1993; 92:535-40.
8. Gern JE, Busse WW. The role of viral infections in the natural history of asthma. J Allergy Clin Immunol 2000; 106:201-12.
9. Renzi PM, Turgeon JP, Yang JP et al. Cellular immunity is activated and a TH-2 response is associated with early wheezing in infants after bronchiolitis. J Pediatr 1997; 130:584-93.
10. Nagayama Y, Sakurai N, Nakahara T et al. Allergic predisposition among infants with bronchiolitis. J Asthma 1987; 24:9-17.
11. Stein Rr, Sherrill D, Morgan WJ et al. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 1999;354:541-5.
12. Sigurs N, Bjarnason R, Sigurbergsson F, Kjellman B. Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med 2000; 161:1501-7.
13. Castro-Rodriguez JA, Holberg CJ, Wright AL, Martinez FD. A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med 2000;162:1403-6.
14. Koller DY, Wojnarowski C, Herkner KR et al. High levels of eosinophil cationic protein in wheezing infants predict the development of asthma. J Allergy Clin Immunol 1997; 99:752-6.
15. Ingram JM, Rakes GP, Hoover GE, Platts-Mills TA, Heymann PW. Eosinophil cationic protein in serum and nasal washes from wheezing infants and children. J Pediatr 1995;127:558-64.
16. Rakes GP, Arruda. E, Ingram JM et al. Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. IgE and eosinophil analyses. Am J Respir Crit Care Med 1999; 159:785-90.
17. Ehlenfield DR, Cameron K, Welliver RC. Eosinophilia at the time of respiratory syncytial virus bronchiolitis predicts childhood reactive airway disease. Pediatrics 2000; 105:79-83.
18. Martinez FD, Stern DA, Wright AL, Maussig LM, Halonen M. Differential immune responses to acute lower respiratory illness in early life and subsequent development of persistent wheezing and asthma. J Allergy Clin Immunol 1998;102:915-20.
19. Calvo Rey C, Garcia Garcia M, Albanil Ballesteros M. [Bronchiolitis and persistent wheezing. Is eosinophilia a risk factor?]. An Esp Pediatr 2001;55:511-6 (in Spanish).
20. Reijonen TM, Korppi M, Kuikka L et al. Serum eosinophil cationic protein as a predictor of wheezing after bronchiolitis. Pediatr Pulmonol 1997;23:397-403.
21. Pifferi M, Ragazzo V, Caramella D, Baldini G. Eosinophil cationic protein in infants with respiratory syncytial virus bronchiolitis: predictive value for subsequent development of persistent wheezing. Pediatr Pulmonol 2001;31: 419-24.
22. Sigurs N, Bjarnason R, Sigurbergsson F. Eosinophil cationic protein, in nasal secretion and in serum and myeloperoxidase in serum in respiratory syncytial virus bronchiolitis: relation to asthma and atopy. Acta Paediatr 1994; 83:1151-5.
23. Miyoshi M. [Measurement of serum eosinophil cationic protein levels in wheezing infants). Arerugi [Jpn J Allergol] 2002;51:1147-52 (in Japanese).
24. Marguet C, Bocquel N, Benichou J et al. Neutrophil but not eosinophil inflammation is related to the severity of a first acute epidemic bronchiolitis in young infants. Pediatr Allergy Immunol 2007;19:157-65.
25. Yoshihara S, Yamada Y, Abe T, Linden A, Arisaka O. Association of epithelial damage and signs of neutrophil mobilization in the airways during acute exacerbations of paediatric asthma. Clin Exp Immunol 2006;144:212-6.
26. Oymar K, Bjerknes R. Is serum eosinophil cationic protein in bronchiolitis a predictor of asthma? Pediatr Allergy Immunol 1998;9:204-7.
27. Piippo-Savolainen E, Remes S, Korppi M. Does blood eosinophilia in wheezing infants predict later asthma? A prospective 18-20-year follow-up. Allergy Asthma Proc 2007;28:163-9.
28. Shields MD, Brown V, Stevenson EC et al. Serum eosinophilic cationic protein and blood eosinophil counts for the prediction of the presence of airways inflammation in children with wheezing. Clin Exp Allergy 1999;29:1382-9.
29. Priftis KN, Papadopoulou A, Liatsis E, Katsikas D, Nicolaidou P, Kanariou M. Senim eosinophil cationic protein and CD23 in acute RSV bronchiolitis. Med Sci Monit 2005; 11:CR493-7.
30. Pizzichini E, Pizzichini MM, Efthimiadis A, Dolovich J, Hargreave FE. Measuring airway inflammation in asthma: eosinophils and eosinophilic cationic protein in induced sputum compared with peripheral blood. J Allergy Clin Immunol 1997;99:539-44.
31. Reijonen TM, Korppi M, Kleemola M et al. Nasopharyngeal eosinophil cationic protein in bronchiolitis: relation to viral findings and subsequent wheezing. Pediatr Pulmonol 1997;24:35-41.
32. Chung HL, Kim SG. RANTES may be predictive of later recurrent wheezing after respiratory syncytial virus bronchiolitis in infants. Ann Allergy Asthma Immunol 2002;88: 463-7.
33. Culley FJ, Pollott J, Openshaw PJ. Age at first viral infection determines the pattern of T cell-mediated disease during reinfection in adulthood. J Exp. Med 2002;196: 1381-6.
34. Grossman J. One airway, one disease. Chest 1997;111: 11S-6S.
35. Gern JR, French DA, Grindle KA, Brockman-Schneider RA, Konno S, Busse WW. Double-strmded RNA induces the synthesis of specific chemokines by bronchial epithelial cells. Am J Respir Cell Mol Biol 2003; 28:731-7.
36. Bochner BS. Road signs guiding leukocytes along the inflammation superhighway. J Allergy Clin Immunol 2000; 106:817-28.
37. Fujisawa T, Kato Y, Nagase H et al. Chemokines induce eosinophil degranulation through CCR-3. J Allergy Clin Immunol 2000; 106:507-13.
38. Krawiec ME, Westcott JY, Chu HW et al. Persistent wheezing in very young children is associated with lower respiratory inflammation. Am J Respir Crit Care Med 2001; 163:1338-43.
39. Reijonen T, Korppi M, Kuikka L, Remes K. Antiinflammatory therapy reduces wheezing after bronchiolitis. Arch Pediatr Adolesc Med 1996;150:512-7.
40. Bisgaard H. A randomized trial of montelukast in respiratory syncytial virus postbronchiolitis. Am J Respir Crit Care Med 2003; 167:379-83.
41. Bisgaard H, Hermansen MN, Loland L, Halkjaer LB, Buchvald F. Intermittent inhaled corticosteroids in infants with episodic wheezing. N Engl J Med 2006;354:1998-2005.
42. Simpson A, Custovic A. Allergen avoidance in the primary prevention of asthma. Curr Opin Allergy Clin Immunol 2004;4:45-51.
43. Korppi M, Kotaniemi-Syrjanen A, Waris M, Vainionpaa R, Reijonen TM. Rhinovirus-associated wheezing in infancy: comparison with respiratory syncytial virus bronchiolitis. Pediatr Infect Dis J 2004; 23:995-9.
44. Kim HH, Lee MH, Lee JS. Eosinophil cationic protein and chemokines in nasopharyngeal secretions of infants with respiratory syncytial virus (RSV) bronchiolitis and non-RSV bronchiolitis. J Korean Med Sci 2007;22:37-42.
45. Saito T, Deskin RW, Casola A et al. Respiratory syncytial virus induces selective production of the chemokine RANTES by upper airway epithelial cells. J Infect Dis 1997; 175:497-504.
46. Harrison AM, Bonville CA, Rosenberg HF, Domachowske JB. Respiratory syncytical virus-induced chemokine expression in the lower airways: eosinophil recruitment and degranulation. Am J Respir Crit Care Med 1999;159: 1918-24.
47. Kimpen JL, Garofalo R, Welliver RC, Fujihara K, Ogra PL. An ultrastructural study of the interaction of human eosinophils with respiratory syncytial virus. Pediatr Allergy Immunol 1996; 7:48-53.
48. Olszewska-Pazdrak B, Pazdrak K, Ogra PL, Garofalo RP. Respiratory syncytial virus-infected pulmonary epithelial cells induce eosinophil degranulation by a CD18-mediated mechanism. J Immunol 1998; 160:4889-95.
49. Matsumoto K, Shimanouchi Y, Kawakubo K et al. Infantile eczema at one month of age is associated with cord blood eosinophilia and subsequent development of atopic dermatitis and wheezing illness until two years of age. Int Arch Allergy Immunol 2005; 137(Suppl1):69-76.
50. Matsumoto K, Tamari M, Saito H. Involvement of eosinophils in the onset of asthma. J Allergy Clin Immunol 2008; 121:26-7.