In vivo measurement of signaling cascade dynamics

Cell Cycle

Volumn 8, Issue 3, 2009, Pages 373-376

  McClean, Megan N ^a,d   Hersen, Pascal ^a,b   Ramanathan, Sharad ^a,c  

^a UNIVERSITÉ PARIS DIDEROT   (France)

^b CNRS   (France)

^c HARVARD UNIVERSITY   (United States)

^d HARVARD UNIVERSITY   (United States)

Author keywords

Bandwidth; Budding yeast; HOG; Information processing; Microfluidics; Mitogen activated kinase pathways (MAPK); Signaling pathways

Indexed keywords

HIGH OSMOLARITY GLYCEROL RESPONSE MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

BIOLOGY; CELL FUNCTION; CELL SIGNALING; DEVICE; IN VIVO STUDY; MICROFLUIDICS; NONHUMAN; REVIEW; STIMULUS;

SACCHAROMYCETALES;

EID: 59449103620     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.3.7450     Document Type: Review

References (27)

1. Klipp E, Nordlander B, Kruger R, Gennemark P, Hohmann S. Integrative model of the response of yeast to osmotic shock. Nat Biotechnol 2005; 23:975-82.
2. Bennett MR, Pang WL, Ostroff NA, Baumgartner BL, Nayak S, Tsimring LS, et al. Metabolic gene regulation in a dynamically changing environment. Nature 2008; 454:1119-22.
3. Hersen P, McClean MN, Mahadevan L, Ramanathan S. Signal processing by the HOG MAP kinase pathway. Proc Natl Acad Sci USA 2008; 105:7165-70.
4. Mettetal JT, Muzzey D, Gomez-Uribe C, van Oudenaarden A. The frequency dependence of osmo-adaptation in Saccharomyces cerevisiae. Science 2008; 319:482-4.
5. Block SM, Segall JE, Berg HC. Impulse responses in bacterial chemotaxis. Cell 1982; 31:215-26.
6. Block SM, Segall JE, Berg HC. Adaptation kinetics in bacterial chemotaxis. J Bacteriol 1983; 154:312-23.
7. Segall JE, Block SM, Berg HC. Temporal comparisons in bacterial chemotaxis. Proc Natl Acad Sci USA 1986; 83:8987-91.
8. Lipan O, Wong WH. The use of oscillatory signals in the study of genetic networks. Proc Natl Acad Sci USA 2005; 102:7063-8.
9. Hohmann S. Osmotic stress signaling and osmoadaptation in yeasts. Microbiol Mol Biol Rev 2002; 66:300-72.
10. Hohmann S, Krantz M, Nordlander B. Yeast osmoregulation. Methods Enzymol 2007; 428:29-45.
11. Alepuz PM, de Nadal E, Zapater M, Ammerer G, Posas F. Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II. EMBO J 2003; 22:2433-42.
12. Alepuz PM, Jovanovic A, Reiser V, Ammerer G. Stress-induced map kinase Hog1 is part of transcription activation complexes. Mol Cell 2001; 7:767-77.
13. De Nadal E, Zapater M, Alepuz PM, Sumoy L, Mas G, Posas F. The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes. Nature 2004; 427:370-4.
14. Pokholok DK, Zeitlinger J, Hannett NM, Reynolds DB, Young RA. Activated signal transduction kinases frequently occupy target genes. Science 2006; 313:533-6.
15. Proft M, Struhl K. Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress. Mol Cell 2002; 9:1307-17.
16. Posas F, Saito H. Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator. EMBO J 1998; 17:1385-94.
17. Posas F, Wurgler-Murphy SM, Maeda T, Witten EA, Thai TC, Saito H. Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor. Cell 1996; 86:865-75.
18. Posas F, Witten EA, Saito H. Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway. Mol Cell Bio 1998; 18:5788-96.
19. Tatebayashi K, Tanaka K, Yang HY, Yamamoto K, Matsushita Y, Tomida T, et al. Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J 2007; 26:3521-33.
20. Tatebayashi K, Yamamoto K, Tanaka K, Tomida T, Maruoka T, Kasukawa E, et al. Adaptor functions of Cdc42, Ste50 and Sho1 in the yeast osmoregulatory HOG MAPK pathway. EMBO J 2006; 25:3033-44.
21. Catlett NL, Yoder OC, Turgeon BG. Whole-genome analysis of two-component signal transduction genes in fungal pathogens. Euk Cell 2003; 2:1151-61.
22. Reiser V, Raitt DC, Saito H. Yeast osmosensor Sln1 and plant cytokinin receptor Cre1 respond to changes in turgor pressure. J Cell Biol 2003; 161:1035-40.
23. Bahn YS, Xue C, Idnurm A, Rutherford JC, Heitman J, Cardenas ME. Sensing the environment: lessons from fungi. Nat Rev Micro 2007; 5:57-69.
24. Furukawa K, Hoshi Y, Maeda T, Nakajima T, Abe K. Aspergillus nidulans HOG pathway is activated only by two-component signalling pathway in response to osmotic stress. Mol Microbiol 2005; 56:1246-61.
25. Krantz M, Becit E, Hohmann S. Comparative genomics of the HOG-signalling system in fungi. Curr Genet 2006; 49:137-51.
26. Beebe DJ, Mensing GA, Walker GM. Physics and applications of microfluidics in biology. Ann Rev Biomed Eng 2002; 4:261-86.
27. Maeda T, Takekawa M, Saito H. Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor. Science 1995; 269:554-8.