-
1
-
-
3242677639
-
siRNAs: Applications in functional genomics and potential as therapeutics
-
Dorsett Y, Tuschl T. siRNAs: applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov 2004; 3: 318-329.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
2
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nat Rev Genet 2002; 3: 737-747.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
Sharp, P.A.2
-
3
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
4
-
-
0029166432
-
Antisense therapy for angioplasty restenosis. Some critical considerations
-
Bennett MR, Schwartz SM. Antisense therapy for angioplasty restenosis. Some critical considerations. Circulation 1995; 92: 1981-93.
-
(1995)
Circulation
, vol.92
, pp. 1981-1993
-
-
Bennett, M.R.1
Schwartz, S.M.2
-
5
-
-
6344219578
-
Deoxyribozymes: DNA catalysts for bioorganic chemistry
-
Silverman SK. Deoxyribozymes: DNA catalysts for bioorganic chemistry. Org Biomol Chem 2004; 2: 2701-2706.
-
(2004)
Org Biomol Chem
, vol.2
, pp. 2701-2706
-
-
Silverman, S.K.1
-
6
-
-
25144480918
-
Hammerhead ribozymes targeted against cyclin E and E2F1 cooperate to down-regulate coronary smooth muscle cell proliferation
-
Grassi G, Schneider A, Engel S, Racchi G, Kandolf R, Kuhn A. Hammerhead ribozymes targeted against cyclin E and E2F1 cooperate to down-regulate coronary smooth muscle cell proliferation. J Gene Med 2005; 7: 1223-1234.
-
(2005)
J Gene Med
, vol.7
, pp. 1223-1234
-
-
Grassi, G.1
Schneider, A.2
Engel, S.3
Racchi, G.4
Kandolf, R.5
Kuhn, A.6
-
7
-
-
33749569829
-
Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice
-
Chetty C, Bhoopathi P, Joseph P, Chittivelu S, Rao JS, Lakka S. Adenovirus-mediated small interfering RNA against matrix metalloproteinase-2 suppresses tumor growth and lung metastasis in mice. Mol Cancer Ther 2006; 5: 2289-2299.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2289-2299
-
-
Chetty, C.1
Bhoopathi, P.2
Joseph, P.3
Chittivelu, S.4
Rao, J.S.5
Lakka, S.6
-
8
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song E, Lee SK, Wang J, et al.. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 2003; 9: 347-351.
-
(2003)
Nat Med
, vol.9
, pp. 347-351
-
-
Song, E.1
Lee, S.K.2
Wang, J.3
-
9
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
McCaffrey AP, Nakai H, Pandey K, et al.. Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol 2003; 21: 639-644.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 639-644
-
-
McCaffrey, A.P.1
Nakai, H.2
Pandey, K.3
-
10
-
-
33645500266
-
Progress towards in vivo use of siRNAs
-
Behlke MA. Progress towards in vivo use of siRNAs. Mol Ther 2006; 13: 644-670.
-
(2006)
Mol Ther
, vol.13
, pp. 644-670
-
-
Behlke, M.A.1
-
11
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek J, Akinc A, Bramlage B, et al.. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 2004; 432: 173-178.
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
-
12
-
-
0034650348
-
Cardiovascular gene therapy
-
Yla-Herttuala S, Martin JF. Cardiovascular gene therapy. Lancet 2000; 355: 213-222.
-
(2000)
Lancet
, vol.355
, pp. 213-222
-
-
Yla-Herttuala, S.1
Martin, J.F.2
-
13
-
-
33746883220
-
A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium
-
Santel A, Aleku M, Keil O, et al.. A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium. Gene Ther 2006; 13: 1222-1234.
-
(2006)
Gene Ther
, vol.13
, pp. 1222-1234
-
-
Santel, A.1
Aleku, M.2
Keil, O.3
-
14
-
-
3242677639
-
siRNAs: Applications in functional genomics and potential as therapeutics
-
Dorsett Y, Tuschl T. siRNAs: applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov 2004; 3: 318-329.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
15
-
-
15044354554
-
RNAi-induced gene silencing by local electroporation in targeting brain region
-
Akaneya Y, Jiang B, Tsumoto T. RNAi-induced gene silencing by local electroporation in targeting brain region. J Neurophysiol 2005; 93: 594-602.
-
(2005)
J Neurophysiol
, vol.93
, pp. 594-602
-
-
Akaneya, Y.1
Jiang, B.2
Tsumoto, T.3
-
16
-
-
0038748037
-
Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in amouse model
-
Reich SJ, Fosnot J, Kuroki A, et al.. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in amouse model. Mol Vis 2003; 9: 210-216.
-
(2003)
Mol Vis
, vol.9
, pp. 210-216
-
-
Reich, S.J.1
Fosnot, J.2
Kuroki, A.3
-
17
-
-
33748331337
-
RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy
-
Santel A, Aleku M, Keil O, et al.. RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy. Gene Ther 2006; 13: 1360-1370.
-
(2006)
Gene Ther
, vol.13
, pp. 1360-1370
-
-
Santel, A.1
Aleku, M.2
Keil, O.3
-
18
-
-
34547113318
-
The functional consequence of RhoA knockdown by RNA interference in rat cerebral arteries
-
Corteling RL, Brett SE, Yin H, Zheng XL, Walsh MP, Welsh DG. The functional consequence of RhoA knockdown by RNA interference in rat cerebral arteries. Am J Physiol Heart Circ Physiol 2007; 293: H440-447.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Corteling, R.L.1
Brett, S.E.2
Yin, H.3
Zheng, X.L.4
Walsh, M.P.5
Welsh, D.G.6
-
19
-
-
0028063408
-
Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
-
Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994; 94: 2493-2503.
-
(1994)
J Clin Invest
, vol.94
, pp. 2493-2503
-
-
Galis, Z.S.1
Sukhova, G.K.2
Lark, M.W.3
Libby, P.4
-
20
-
-
0036792538
-
Low molecular weight fucoidan prevents neointimal hyperplasia in rabbit iliac artery in-stent restenosis model
-
Deux JF, Meddahi-Pelle A, Le Blanche AF, et al.. Low molecular weight fucoidan prevents neointimal hyperplasia in rabbit iliac artery in-stent restenosis model. Arterioscler Thromb Vasc Biol 2002; 22: 1604-1609.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1604-1609
-
-
Deux, J.F.1
Meddahi-Pelle, A.2
Le Blanche, A.F.3
-
21
-
-
0034001964
-
Interleukin-10 inhibits intimal hyperplasia after angioplasty or stent implantation in hypercholesterolemic rabbits
-
Feldman LJ, Aguirre L, Ziol M, et al.. Interleukin-10 inhibits intimal hyperplasia after angioplasty or stent implantation in hypercholesterolemic rabbits. Circulation 2000; 101: 908-916.
-
(2000)
Circulation
, vol.101
, pp. 908-916
-
-
Feldman, L.J.1
Aguirre, L.2
Ziol, M.3
-
22
-
-
0033854954
-
Molecular plasticity of vascular wall during N(G)-nitro-L-arginine methyl ester-induced hypertension: Modulation of proinflammatory signals
-
Gonzalez W, Fontaine V, Pueyo ME, et al.. Molecular plasticity of vascular wall during N(G)-nitro-L-arginine methyl ester-induced hypertension: modulation of proinflammatory signals. Hypertension 2000; 36: 103-109.
-
(2000)
Hypertension
, vol.36
, pp. 103-109
-
-
Gonzalez, W.1
Fontaine, V.2
Pueyo, M.E.3
-
23
-
-
0038718531
-
Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species
-
Grote K, Flach I, Luchtefeld M, et al.. Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species. Circ Res 2003; 92: 80-86.
-
(2003)
Circ Res
, vol.92
, pp. 80-86
-
-
Grote, K.1
Flach, I.2
Luchtefeld, M.3
-
24
-
-
0033828464
-
Increased TIMP/MMP ratio in varicose veins: A possible explanation for extracellular matrix accumulation
-
Badier-Commander C, Verbeuren T, Lebard C, Michel JB, Jacob MP. Increased TIMP/MMP ratio in varicose veins: a possible explanation for extracellular matrix accumulation. J Pathol 2000; 192: 105-112.
-
(2000)
J Pathol
, vol.192
, pp. 105-112
-
-
Badier-Commander, C.1
Verbeuren, T.2
Lebard, C.3
Michel, J.B.4
Jacob, M.P.5
-
25
-
-
0035954307
-
Differential expression of matrix metalloproteinases after stent implantation and balloon angioplasty in the hypercholesterolemic rabbit
-
Feldman LJ, Mazighi M, Scheuble A, et al.. Differential expression of matrix metalloproteinases after stent implantation and balloon angioplasty in the hypercholesterolemic rabbit. Circulation 2001; 103: 3117-3122.
-
(2001)
Circulation
, vol.103
, pp. 3117-3122
-
-
Feldman, L.J.1
Mazighi, M.2
Scheuble, A.3
-
26
-
-
0348014774
-
Approaches for the sequence-specific knockdown of mRNA
-
Scherer LJ, Rossi JJ. Approaches for the sequence-specific knockdown of mRNA. Nat Biotechnol 2003; 21: 1457-1465.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 1457-1465
-
-
Scherer, L.J.1
Rossi, J.J.2
-
27
-
-
0036385852
-
Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
-
Bertrand JR, Pottier M, Vekris A, Opolon P, Maksimenko A, Malvy C. Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem Biophys Res Commun 2002; 296: 1000-1004.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 1000-1004
-
-
Bertrand, J.R.1
Pottier, M.2
Vekris, A.3
Opolon, P.4
Maksimenko, A.5
Malvy, C.6
-
28
-
-
17544378561
-
Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes
-
Macejak DG, Jensen KL, Jamison SF, et al.. Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes. Hepatology 2000; 31: 769-776.
-
(2000)
Hepatology
, vol.31
, pp. 769-776
-
-
Macejak, D.G.1
Jensen, K.L.2
Jamison, S.F.3
-
29
-
-
34547487035
-
Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin
-
Chen Y, Lin MC, Yao H, et al.. Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin. Hepatology 2007; 46: 200-208.
-
(2007)
Hepatology
, vol.46
, pp. 200-208
-
-
Chen, Y.1
Lin, M.C.2
Yao, H.3
-
30
-
-
34447114618
-
Transvascular delivery of small interfering RNA to the central nervous system
-
Kumar P, WuH, McBride JL, et al.. Transvascular delivery of small interfering RNA to the central nervous system. Nature 2007; 448: 39-43.
-
(2007)
Nature
, vol.448
, pp. 39-43
-
-
Kumar, P.1
Wu, H.2
McBride, J.L.3
-
31
-
-
0041808932
-
Gene therapy progress and prospects: Adenoviral vectors
-
St George JA. Gene therapy progress and prospects: adenoviral vectors. Gene Ther 2003; 10: 1135-1141.
-
(2003)
Gene Ther
, vol.10
, pp. 1135-1141
-
-
St George, J.A.1
-
32
-
-
0029013211
-
Low-efficiency of percutaneous adenovirus-mediated arterial gene transfer in the atherosclerotic rabbit
-
Feldman LJ, Steg PG, Zheng LP, et al.. Low-efficiency of percutaneous adenovirus-mediated arterial gene transfer in the atherosclerotic rabbit. J Clin Invest 1995; 95: 2662-2671.
-
(1995)
J Clin Invest
, vol.95
, pp. 2662-2671
-
-
Feldman, L.J.1
Steg, P.G.2
Zheng, L.P.3
-
33
-
-
15444373116
-
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
-
Urban-Klein B, Werth S, Abuharbeid S, Czubayko F, Aigner A. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther 2005; 12: 461-466.
-
(2005)
Gene Ther
, vol.12
, pp. 461-466
-
-
Urban-Klein, B.1
Werth, S.2
Abuharbeid, S.3
Czubayko, F.4
Aigner, A.5
-
34
-
-
36849018610
-
Inhibition of MMP2 gene expression with small interfering RNA in rabbit vascular smooth muscle cells
-
Hlawaty H, San Juan A, Jacob MP, Vranckx R, Letourneur D, Feldman L. Inhibition of MMP2 gene expression with small interfering RNA in rabbit vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 2007; 293: H3593-H3601.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Hlawaty, H.1
San Juan, A.2
Jacob, M.P.3
Vranckx, R.4
Letourneur, D.5
Feldman, L.6
-
35
-
-
36649030332
-
Delivery of large biopharmaceuticals from cardiovascular stents: A review
-
Takahashi H, Letourneur D, Grainger DW. Delivery of large biopharmaceuticals from cardiovascular stents: a review. Biomacromolecules 2007; 8: 3281-3293.
-
(2007)
Biomacromolecules
, vol.8
, pp. 3281-3293
-
-
Takahashi, H.1
Letourneur, D.2
Grainger, D.W.3
-
36
-
-
0038610713
-
Caspase 8 small interfering RNA prevents acute liver failure in mice
-
Zender L, Hutker S, Liedtke C, et al.. Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc Natl Acad Sci USA 2003; 100: 7797-7802.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7797-7802
-
-
Zender, L.1
Hutker, S.2
Liedtke, C.3
-
37
-
-
28444497388
-
Transporting silence: Design of carriers for siRNA to angiogenic endothelium
-
Schiffelers RM, Mixson AJ, Ansari AM, et al.. Transporting silence: design of carriers for siRNA to angiogenic endothelium. J Control Release 2005; 109: 5-14.
-
(2005)
J Control Release
, vol.109
, pp. 5-14
-
-
Schiffelers, R.M.1
Mixson, A.J.2
Ansari, A.M.3
-
39
-
-
0036851826
-
Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies
-
Dzau VJ, Braun-Dullaeus RC, Sedding DG. Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies. Nat Med 2002; 8: 1249-1256.
-
(2002)
Nat Med
, vol.8
, pp. 1249-1256
-
-
Dzau, V.J.1
Braun-Dullaeus, R.C.2
Sedding, D.G.3
-
40
-
-
33747872678
-
Controlled release of small interfering RNA targeting midkine attenuates intimal hyperplasia in vein grafts
-
Banno H, Takei Y, Muramatsu T, Komori K, Kadomatsu K. Controlled release of small interfering RNA targeting midkine attenuates intimal hyperplasia in vein grafts. J Vasc Surg 2006; 44: 633-641.
-
(2006)
J Vasc Surg
, vol.44
, pp. 633-641
-
-
Banno, H.1
Takei, Y.2
Muramatsu, T.3
Komori, K.4
Kadomatsu, K.5
-
41
-
-
34047219787
-
Inhibition of intrinsic interferon-gamma function prevents neointima formation after balloon injury
-
Kusaba K, Kai H, Koga M, et al.. Inhibition of intrinsic interferon-gamma function prevents neointima formation after balloon injury. Hypertension 2007; 49: 909-915.
-
(2007)
Hypertension
, vol.49
, pp. 909-915
-
-
Kusaba, K.1
Kai, H.2
Koga, M.3
|