Memantine for prophylaxis of chronic tension-type headache - A double-blind, randomized, crossover clinical trial

Cephalalgia

Volumn 29, Issue 3, 2009, Pages 314-321

  Lindelof, K ^a   Bendtsen, L ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Central sensitization; Memantine; NMDA receptor antagonist; Prophylactic treatment; Tension type headache

Indexed keywords

ANALGESIC AGENT; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PLACEBO;

ADULT; AREA UNDER THE CURVE; ARTICLE; BEDTIME DOSAGE; BLURRED VISION; CHRONIC TENSION HEADACHE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE SEVERITY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG SAFETY; DRUG USE; DRUG WITHDRAWAL; FATIGUE; FEMALE; HEART PALPITATION; HUMAN; INCREASED APPETITE; INFECTION; MALE; MOOD CHANGE; MUSCLE CRAMP; MYALGIA; NAUSEA; OUTCOME ASSESSMENT; PAIN ASSESSMENT; PARESTHESIA; PATIENT COMPLIANCE; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RESTLESSNESS; SEX DIFFERENCE; SIDE EFFECT; SLEEP DISORDER; TREATMENT DURATION; TREATMENT INDICATION; TREATMENT OUTCOME; VOMITING; XEROSTOMIA;

ADULT; CHRONIC DISEASE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HUMANS; MALE; MEMANTINE; MIDDLE AGED; TENSION-TYPE HEADACHE;

EID: 59249108401     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1111/j.1468-2982.2008.01720.x     Document Type: Article

References (42)

1. Lyngberg AC, Rasmussen BK, Jorgensen T, Jensen R. Has the prevalence of migraine and tension-type headache changed over a 12-year period? A Danish population survey. Eur J Epidemiol 2005 20 : 243 9.
2. Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders: 2nd edition. Cephalalgia 2004 24 (Suppl. 1 9 160.
3. Bendtsen L, Jensen R. Tension-type headache: the most common, but also the most neglected, headache disorder. Curr Opin Neurol 2006 19 : 305 9.
4. Bendtsen L. Central sensitization in tension-type headache - possible pathophysiological mechanisms. Cephalalgia 2000 20 : 486 508.
5. Bendtsen L, Treede RD. Sensitization of myofascial pain pathways in tension-type headaches. In : Olesen J, Goadsby PJ, Ramadan N, Tfelt-Hansen P, Welch KM, eds. The headaches. Philadelphia, PA : Lippincott Williams and Wilkins 2005 635 9.
6. Buchgreitz L, Lyngberg AC, Bendtsen L, Jensen R. Increased pain sensitivity is not a risk factor but a consequence of frequent headache. A population-based follow-up study. Pain 2008 137 : 623 30.
7. Woolf CJ, Thompson SW. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain 1991 44 : 293 9.
8. Willert RP, Delaney C, Kelly K, Sharma A, Aziz Q, Hobson AR. Exploring the neurophysiological basis of chest wall allodynia induced by experimental oesophageal acidification - evidence of central sensitization. Neurogastroenterol Motil 2007 19 : 270 8.
9. Benrath J, Brechtel C, Stark J, Sandkuhler J. Low dose of S+-ketamine prevents long-term potentiation in pain pathways under strong opioid analgesia in the rat spinal cord in vivo. Br J Anaesth 2005 95 : 518 23.
10. Robinson DM, Keating GM. Memantine: a review of its use in Alzheimer's disease. Drugs 2006 66 : 1515 34.
11. Planells-Cases R, Lerma J, Ferrer-Montiel A. Pharmacological intervention at ionotropic glutamate receptor complexes. Curr Pharm Des 2006 12 : 3583 96.
12. Mathew NT. Tension-type headache. Curr Neurol Neurosci Rep 2006 6 : 100 5.
13. Russell MB, Rasmussen BK, Brennum J, Iversen HK, Jensen R, Olesen J. Presentation of a new instrument: the diagnostic headache diary. Cephalalgia 1992 12 : 369 74.
14. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960 23 : 56 62.
15. Hutchinson D. ICH harmonised tripartite guideline for good clinical practice, 2nd edn. Richmond-on-Thames, UK : Brookwood Medical Publications Ltd 1997.
16. Langemark M, Olesen J. Pericranial tenderness in tension headache. A blind, controlled study. Cephalalgia 1987 7 : 249 55.
17. Altman DG. Clinical trials. Practical statistics for medical research. New York : Chapman and Hall 1991 440 76.
18. Schoenen J. Guidelines for trials of drug treatments in tension-type headache. First edition: International Headache Society Committee on clinical trials. Cephalalgia 1995 15 : 165 79.
19. Bendtsen L, Jensen R. Mirtazapine is effective in the prophylactic treatment of chronic tension-type headache. Neurology 2004 62 : 1706 11.
20. Bendtsen L, Jensen R, Olesen J. A non-selective (amitriptyline), but not a selective (citalopram), serotonin reuptake inhibitor is effective in the prophylactic treatment of chronic tension-type headache. J Neurol Neurosurg Psychiatry 1996 61 : 285 90.
21. Holroyd KA, O'Donnell FJ, Stensland M, Lipchik GL, Cordingley GE, Carlson BW. Management of chronic tension-type headache with tricyclic antidepressant medication, stress management therapy, and their combination: a randomized controlled trial. JAMA 2001 285 : 2208 15.
22. Munce SEP, Stewart DE. Gender differences in depression and chronic pain conditions in a national epidemiologic survey. Psychosomatics 2007 48 : 394 9.
23. McRoberts JA, Li J, Ennes HS, Mayer EA. Sex-dependent differences in the activity and modulation of N-methyl-D-aspartic acid receptors in rat dorsal root ganglia neurons. Neuroscience 2007 148 : 1015 20.
24. Senn S. Cross-over trials in clinical research, 2nd edn. Chichester : John Wiley & Sons Ltd. 2002.
25. Walker Z, Walker RW, Robertson MM, Stansfeld S. Antidepressant treatment of chronic tension-type headache: a comparison between fluoxetine and desipramine. Headache 1998 38 : 523 8.
26. Zissis NP, Harmoussi S, Vlaikidis N, Mitsikostas D, Thomaidis T, Georgiadis G et al. A randomized, double-blind, placebo-controlled study of venlafaxine XR in out-patients with tension-type headache. Cephalalgia 2007 27 : 315 24.
27. Charles A, Flippen C, Romero RM, Brennan KC. Memantine for prevention of migraine: a retrospective study of 60 cases. J Headache Pain 2007 8 : 248 50.
28. Carlton SM, Hargett GL. Treatment with the NMDA antagonist memantine attenuates nociceptive responses to mechanical stimulation in neuropathic rats. Neurosci Lett 1995 198 : 115 18.
29. Carlton SM, Rees H, Tsuruoka M, Willis WD. Memantine attenuates responses of spinothalamic tract cells to cutaneous stimulation in neuropathic monkeys. Eur J Pain 1998 2 : 229 38.
30. Willis WD, Jr. The somatosensory system, with emphasis on structures important for pain. Brain Res Rev 2007 55 : 297 313.
31. Zhang GH, Min SS, Lee KS, Back SK, Yoon SJ, Yoon YW et al. Intraarticular pretreatment with ketamine and memantine could prevent arthritic pain: relevance to the decrease of spinal c-fos expression in rats. Anesth Analg 2004 99 : 152 8.
32. Medvedev IO, Malyshkin AA, Belozertseva IV, Sukhotina IA, Sevostianova NY, Aliev K et al. Effects of low-affinity NMDA receptor channel blockers in two rat models of chronic pain. Neuropharmacology 2004 47 : 175 83.
33. Berrino L, Oliva P, Massimo F, Aurilio C, Maione S, Grella A et al. Antinociceptive effect in mice of intraperitoneal N-methyl-D-aspartate receptor antagonists in the formalin test. Eur J Pain 2003 7 : 131 7.
34. Sinis N, Birbaumer N, Gustin S, Schwarz A, Bredanger S, Becker ST et al. Memantine treatment of complex regional pain syndrome: a preliminary report of six cases. Clin J Pain 2007 23 : 237 43.
35. Wiech K, Kiefer RT, Topfner S, Preissl H, Braun C, Unertl K et al. A placebo-controlled randomized crossover trial of the N-methyl-D-aspartic acid receptor antagonist, memantine, in patients with chronic phantom limb pain. Anesth Analg 2004 98 : 408 13, table.
36. Maier C, Dertwinkel R, Mansourian N, Hosbach I, Schwenkreis P, Senne I et al. Efficacy of the NMDA-receptor antagonist memantine in patients with chronic phantom limb pain - results of a randomized double-blinded, placebo-controlled trial. Pain 2003 103 : 277 83.
37. Eisenberg E, Kleiser A, Dortort A, Haim T, Yarnitsky D. The NMDA (N-methyl-D-aspartate) receptor antagonist memantine in the treatment of postherpetic neuralgia: a double-blind, placebo-controlled study. Eur J Pain 1998 2 : 321 7.
38. Sang CN, Booher S, Gilron I, Parada S, Max MB. Dextromethorphan and memantine in painful diabetic neuropathy and postherpetic neuralgia: efficacy and dose-response trials. Anesthesiology 2002 96 : 1053 61.
39. Nikolajsen L, Gottrup H, Kristensen AG, Jensen TS. Memantine (a N-methyl-D-aspartate receptor antagonist) in the treatment of neuropathic pain after amputation or surgery: a randomized, double-blinded, cross-over study. Anesth Analg 2000 91 : 960 6.
40. Schifitto G, Yiannoutsos CT, Simpson DM, Marra CM, Singer EJ, Kolson DL et al. A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy. J Neurovirol 2006 12 : 328 31.
41. Schley M, Topfner S, Wiech K, Schaller HE, Konrad CJ, Schmelz M et al. Continuous brachial plexus blockade in combination with the NMDA receptor antagonist memantine prevents phantom pain in acute traumatic upper limb amputees. Eur J Pain 2007 11 : 299 308.
42. Makowska A, Panfil C, Ellrich J. Nerve growth factor injection into semispinal neck muscle evokes sustained facilitation of the jaw-opening reflex in anesthetized mice - possible implications for tension-type headache. Exp Neurol 2005 191 : 301 9.