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Volumn 2, Issue 3, 1998, Pages 229-238

Memantine attenuates responses of spinothalamic tract cells to cutaneous stimulation in neuropathic monkeys

Author keywords

[No Author keywords available]

Indexed keywords

MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

EID: 0031691817     PISSN: 10903801     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1090-3801(98)90019-2     Document Type: Article
Times cited : (24)

References (49)
  • 1
    • 0025286174 scopus 로고
    • Excitatory amino acid receptors and nociceptive neurotransmission in the rat spinal cord
    • Aanonsen LM, Lei S, Wilcox GL. Excitatory amino acid receptors and nociceptive neurotransmission in the rat spinal cord. Pain 1990; 41: 309-321.
    • (1990) Pain , vol.41 , pp. 309-321
    • Aanonsen, L.M.1    Lei, S.2    Wilcox, G.L.3
  • 2
    • 0023897040 scopus 로고
    • Treatment of impaired cerebral function in psychogeriatric patients with memantine-results of a phase II double-blind study
    • Ambrozi L, Danielcyzk W. Treatment of impaired cerebral function in psychogeriatric patients with memantine-results of a phase II double-blind study. Pharmacopsychiatry 1988; 21: 144-146.
    • (1988) Pharmacopsychiatry , vol.21 , pp. 144-146
    • Ambrozi, L.1    Danielcyzk, W.2
  • 3
    • 0027979341 scopus 로고
    • Response of chronic neuropathic pain syndromes to ketamine: A preliminary study
    • Backonja M, Arndt G, Gombar KA, Check B, Zimmermann M. Response of chronic neuropathic pain syndromes to ketamine: a preliminary study. Pain 1994; 56: 51-57.
    • (1994) Pain , vol.56 , pp. 51-57
    • Backonja, M.1    Arndt, G.2    Gombar, K.A.3    Check, B.4    Zimmermann, M.5
  • 4
    • 0000021833 scopus 로고
    • Causalgia and other reflex sympathetic dystrophies
    • J. J. Bonica, editor. Philadelphia, PA: Lea and Febiger
    • Bonica JJ. Causalgia and other reflex sympathetic dystrophies. In: J. J. Bonica, editor. The management of pain, Vol. 2. Philadelphia, PA: Lea and Febiger, 1990; 220-243.
    • (1990) The Management of Pain , vol.2 , pp. 220-243
    • Bonica, J.J.1
  • 5
    • 0028787329 scopus 로고
    • Treatment with the NMDA antagonist memantine attenuates nociceptive responses to mechanical stimulation in neuropathic rats
    • Carlton SM, Hargett GL. Treatment with the NMDA antagonist memantine attenuates nociceptive responses to mechanical stimulation in neuropathic rats. Neurosci Letts 1995; 198: 115-118.
    • (1995) Neurosci Letts , vol.198 , pp. 115-118
    • Carlton, S.M.1    Hargett, G.L.2
  • 6
    • 0028058081 scopus 로고
    • Behavioral manifestations of an experimental model for peripheral neuropathy produced by spinal nerve ligation in the primate
    • Carlton SM, Lekan HA, Kim SH, Chung JM. Behavioral manifestations of an experimental model for peripheral neuropathy produced by spinal nerve ligation in the primate. Pain 1994a; 56: 155-166.
    • (1994) Pain , vol.56 , pp. 155-166
    • Carlton, S.M.1    Lekan, H.A.2    Kim, S.H.3    Chung, J.M.4
  • 7
    • 0013363889 scopus 로고
    • Behavioral and electrophysiological effects of memantine in a primate model of peripheral neuropathy
    • Carlton SM, Rees H, Gondesen K, Tsuruoka M, Willis WD. Behavioral and electrophysiological effects of memantine in a primate model of peripheral neuropathy. Soc for Neurosci 1994b.
    • (1994) Soc for Neurosci
    • Carlton, S.M.1    Rees, H.2    Gondesen, K.3    Tsuruoka, M.4    Willis, W.D.5
  • 9
    • 0026640290 scopus 로고
    • The contribution of excitatory amino acids to central sensitization and persistent nociception after formalin-induced tissue injury
    • Coderre TJ, Melzack R. The contribution of excitatory amino acids to central sensitization and persistent nociception after formalin-induced tissue injury. J Neurosci 1992; 12: 3665-3670.
    • (1992) J Neurosci , vol.12 , pp. 3665-3670
    • Coderre, T.J.1    Melzack, R.2
  • 10
    • 0025769640 scopus 로고
    • MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathy
    • Davar G, Hama A, Deykin A, Vos B, Maciewicz R. MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathy. Brain Res 1991; 553: 327-330.
    • (1991) Brain Res , vol.553 , pp. 327-330
    • Davar, G.1    Hama, A.2    Deykin, A.3    Vos, B.4    Maciewicz, R.5
  • 11
    • 0025375531 scopus 로고
    • A cure for wind up: NMDA receptor antagonists as potential analgesics
    • Dickenson AH. A cure for wind up: NMDA receptor antagonists as potential analgesics. Trends Pharmacol Sci 1990; 11: 307-309.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 307-309
    • Dickenson, A.H.1
  • 12
    • 0026780855 scopus 로고
    • The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli
    • Dougherty PM, Palecek J, Paleckova V, Sorkin LS, Willis WD. The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli. J Neurosci 1992; 12: 3025-3041.
    • (1992) J Neurosci , vol.12 , pp. 3025-3041
    • Dougherty, P.M.1    Palecek, J.2    Paleckova, V.3    Sorkin, L.S.4    Willis, W.D.5
  • 13
    • 0028038355 scopus 로고
    • Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: A double-blind, cross-over comparison with morphine and placebo
    • Eide PK, Jorum E, Stubhaug A, Bremnes J, Breivik H. Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo. Pain 1994; 58: 347-354.
    • (1994) Pain , vol.58 , pp. 347-354
    • Eide, P.K.1    Jorum, E.2    Stubhaug, A.3    Bremnes, J.4    Breivik, H.5
  • 14
    • 0029049804 scopus 로고
    • Continuous subcutaneous administration of the N-methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia
    • Eide PK, Stubhaug A, Oye I, Breivik H. Continuous subcutaneous administration of the N-methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia. Pain 1995; 61: 221-228.
    • (1995) Pain , vol.61 , pp. 221-228
    • Eide, P.K.1    Stubhaug, A.2    Oye, I.3    Breivik, H.4
  • 15
    • 0028890414 scopus 로고
    • The clinically tested N-methyl-D-aspartate receptor antagonist memantine blocks and reverses thermal hyperalgesia in a rat model of painful mononeuropathy
    • Eisenberg E, LaCross S, Strassman AM. The clinically tested N-methyl-D-aspartate receptor antagonist memantine blocks and reverses thermal hyperalgesia in a rat model of painful mononeuropathy. Neurosci Letts 1995; 187: 17-20.
    • (1995) Neurosci Letts , vol.187 , pp. 17-20
    • Eisenberg, E.1    LaCross, S.2    Strassman, A.M.3
  • 16
    • 0025801643 scopus 로고
    • Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate
    • Erdo SL, Schafer M. Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate. Eur J Pharmacol 1991; 198: 215-217.
    • (1991) Eur J Pharmacol , vol.198 , pp. 215-217
    • Erdo, S.L.1    Schafer, M.2
  • 17
    • 0027467438 scopus 로고
    • Region-specific expression of subunits of ionotropic glutamate receptors (AMPA-type, KA-type and NMDA receptors) in the rat spinal cord with special reference to nociception
    • Furuyama T, Kiyama H, Sato K, Park HT, Maeno H, Takagi H, Tohyama M. Region-specific expression of subunits of ionotropic glutamate receptors (AMPA-type, KA-type and NMDA receptors) in the rat spinal cord with special reference to nociception. Mol Brain Res 1993; 18: 141-151.
    • (1993) Mol Brain Res , vol.18 , pp. 141-151
    • Furuyama, T.1    Kiyama, H.2    Sato, K.3    Park, H.T.4    Maeno, H.5    Takagi, H.6    Tohyama, M.7
  • 18
    • 0025307284 scopus 로고
    • Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat
    • Haley J, Sullivan AF, Dickenson AH. Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat. Brain Res 1990; 518: 218-226.
    • (1990) Brain Res , vol.518 , pp. 218-226
    • Haley, J.1    Sullivan, A.F.2    Dickenson, A.H.3
  • 19
    • 0028089148 scopus 로고
    • Memantine selectively depresses NMDA receptor-mediated responses of rat spinal neurones in vivo
    • Herrero JF, Headley PM, Parsons CG. Memantine selectively depresses NMDA receptor-mediated responses of rat spinal neurones in vivo. Neurosci Letts 1994; 165: 37-40.
    • (1994) Neurosci Letts , vol.165 , pp. 37-40
    • Herrero, J.F.1    Headley, P.M.2    Parsons, C.G.3
  • 20
    • 0025131237 scopus 로고
    • Evidence of a role for NMDA receptors in pain perception
    • Klepstad P, Maurset A, Moberg ER, Oye I. Evidence of a role for NMDA receptors in pain perception. Eur J Pharmacol 1990; 187: 513-518.
    • (1990) Eur J Pharmacol , vol.187 , pp. 513-518
    • Klepstad, P.1    Maurset, A.2    Moberg, E.R.3    Oye, I.4
  • 21
    • 0026677223 scopus 로고
    • The NMDA-receptor antagonist CPP abolishes neurogenic 'wind-up pain' after intrathecal administration in humans
    • Kristensen JD, Svensson B, Gordh T. The NMDA-receptor antagonist CPP abolishes neurogenic 'wind-up pain' after intrathecal administration in humans. Pain 1992; 51: 249-253.
    • (1992) Pain , vol.51 , pp. 249-253
    • Kristensen, J.D.1    Svensson, B.2    Gordh, T.3
  • 22
    • 0028023153 scopus 로고
    • Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn
    • Liu H, Wang H, Sheng M, Jan LY, Jan YN, Basbaum AI. Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn. Proc Natl Acad Sci 1994; 91: 8383-8387.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 8383-8387
    • Liu, H.1    Wang, H.2    Sheng, M.3    Jan, L.Y.4    Jan, Y.N.5    Basbaum, A.I.6
  • 23
    • 0027057580 scopus 로고
    • Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy
    • Mao J, Price DD, Hayes RL, Lu J, Mayer DJ. Differential roles of NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy. Brain Res 1992a; 598: 271-278.
    • (1992) Brain Res , vol.598 , pp. 271-278
    • Mao, J.1    Price, D.D.2    Hayes, R.L.3    Lu, J.4    Mayer, D.J.5
  • 24
    • 0027466924 scopus 로고
    • Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy
    • Mao J, Price DD, Hayes RL, Lu J, Mayer DJ, Frenk H. Intrathecal treatment with dextrorphan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy. Brain Res 1993; 605: 164- 168.
    • (1993) Brain Res , vol.605 , pp. 164-168
    • Mao, J.1    Price, D.D.2    Hayes, R.L.3    Lu, J.4    Mayer, D.J.5    Frenk, H.6
  • 25
    • 0026583723 scopus 로고
    • Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy
    • Mao J, Price DD, Mayer DJ, Lu J, Hayes RL. Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy. Brain Res 1992b; 576: 254-262.
    • (1992) Brain Res , vol.576 , pp. 254-262
    • Mao, J.1    Price, D.D.2    Mayer, D.J.3    Lu, J.4    Hayes, R.L.5
  • 26
    • 0029050613 scopus 로고
    • Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain
    • Mathisen LC, Skjelbred P, Skoglund LA, Oye I. Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain. Pain 1995; 61: 215-220.
    • (1995) Pain , vol.61 , pp. 215-220
    • Mathisen, L.C.1    Skjelbred, P.2    Skoglund, L.A.3    Oye, I.4
  • 27
    • 0024499740 scopus 로고
    • Comparison of ketamine and pethidine in experimental and postoperative pain
    • Maurset A, Skoglund LA, Hustveit O, Oye I. Comparison of ketamine and pethidine in experimental and postoperative pain. Pain 1989; 36: 37-41.
    • (1989) Pain , vol.36 , pp. 37-41
    • Maurset, A.1    Skoglund, L.A.2    Hustveit, O.3    Oye, I.4
  • 28
    • 0029125541 scopus 로고
    • Intravenous infusion of the NMDA antagonist, ketamin, in chronic posttraumatic pain with allodynia: A double-blind comparison to alfentanil and placebo
    • Max MB, Byas-Smith MG, Gracely RH, Bennett GJ. Intravenous infusion of the NMDA antagonist, ketamin, in chronic posttraumatic pain with allodynia: a double-blind comparison to alfentanil and placebo. Clin Neuropharmacol 1995; 18: 360-368.
    • (1995) Clin Neuropharmacol , vol.18 , pp. 360-368
    • Max, M.B.1    Byas-Smith, M.G.2    Gracely, R.H.3    Bennett, G.J.4
  • 30
    • 0030992921 scopus 로고    scopus 로고
    • High-dose oral dextromethorphn versus placebo in painful diabetic neuropthy and postherpetic neuralgia
    • Nelson KA, Park KM, Robinovitz E, Max MB. High-dose oral dextromethorphn versus placebo in painful diabetic neuropthy and postherpetic neuralgia. Neurology 1997; 48: 1212-1218.
    • (1997) Neurology , vol.48 , pp. 1212-1218
    • Nelson, K.A.1    Park, K.M.2    Robinovitz, E.3    Max, M.B.4
  • 31
    • 0027374708 scopus 로고
    • The clinically available NMDA receptor antagonist memantine is antinociceptive on rat spinal neurones
    • Neugebauer V, Kornhuber J, Lucke T, Schaible H-G. The clinically available NMDA receptor antagonist memantine is antinociceptive on rat spinal neurones. Neuro Report 1993; 4: 1259-1262.
    • (1993) Neuro Report , vol.4 , pp. 1259-1262
    • Neugebauer, V.1    Kornhuber, J.2    Lucke, T.3    Schaible, H.-G.4
  • 32
    • 0028299707 scopus 로고
    • The involvement of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the responsiveness of rat spinal neurons with input from the chronically inflamed ankle
    • Neugebauer V, Lucke T, Grubb B, Schaible H-G. The involvement of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the responsiveness of rat spinal neurons with input from the chronically inflamed ankle. Neurosci Letts 1994; 170: 237-240.
    • (1994) Neurosci Letts , vol.170 , pp. 237-240
    • Neugebauer, V.1    Lucke, T.2    Grubb, B.3    Schaible, H.-G.4
  • 33
    • 0026741436 scopus 로고
    • Changes in the response states of primate spinothalamic tract cells caused by mechanical damage of the skin or activation of descending controls
    • Owens CM, Zhang D, Willis WD. Changes in the response states of primate spinothalamic tract cells caused by mechanical damage of the skin or activation of descending controls. J Neurophysiol 1992; 67: 1509-1527.
    • (1992) J Neurophysiol , vol.67 , pp. 1509-1527
    • Owens, C.M.1    Zhang, D.2    Willis, W.D.3
  • 34
    • 0027071740 scopus 로고
    • Responses of spinothalamic tract neurons to mechanical and thermal stimuli in an experimental model of peripheral neuropathy in primates
    • Palecek J, Dougherty PM, Kim SH, Paleckova V, Lekan H, Chung JM, Carlton SM, Willis WD. Responses of spinothalamic tract neurons to mechanical and thermal stimuli in an experimental model of peripheral neuropathy in primates. J Neurophysiol 1992; 68: 1951-1966.
    • (1992) J Neurophysiol , vol.68 , pp. 1951-1966
    • Palecek, J.1    Dougherty, P.M.2    Kim, S.H.3    Paleckova, V.4    Lekan, H.5    Chung, J.M.6    Carlton, S.M.7    Willis, W.D.8
  • 35
    • 0028884581 scopus 로고
    • Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects
    • Park KM, Max MB, Robinovitz E, Gracely RH, Bennett GJ. Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects. Pain 1995; 63: 163-172.
    • (1995) Pain , vol.63 , pp. 163-172
    • Park, K.M.1    Max, M.B.2    Robinovitz, E.3    Gracely, R.H.4    Bennett, G.J.5
  • 36
    • 0028857603 scopus 로고
    • Beneficial effects of ketamine in a chronic pain state with allodynia, possibly due to central sensitization
    • Persson J, Axelsson G, Hallin RG, Gustafsson LL. Beneficial effects of ketamine in a chronic pain state with allodynia, possibly due to central sensitization. Pain 1995; 60: 217-222.
    • (1995) Pain , vol.60 , pp. 217-222
    • Persson, J.1    Axelsson, G.2    Hallin, R.G.3    Gustafsson, L.L.4
  • 37
    • 0028157362 scopus 로고
    • Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody
    • Petralia RS, Yokotani N, Wenthold RJ. Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J Neurosci 1994; 14: 667-696.
    • (1994) J Neurosci , vol.14 , pp. 667-696
    • Petralia, R.S.1    Yokotani, N.2    Wenthold, R.J.3
  • 38
    • 0029937786 scopus 로고    scopus 로고
    • Systemic ketamine attenuates nociceptive behaviors in a rat model of peripheral neuropathy
    • Qian J, Brown S, Carlton SM. Systemic ketamine attenuates nociceptive behaviors in a rat model of peripheral neuropathy. Brain Res 1996; 715: 51-62.
    • (1996) Brain Res , vol.715 , pp. 51-62
    • Qian, J.1    Brown, S.2    Carlton, S.M.3
  • 39
    • 0026701318 scopus 로고
    • Efficacy of memantine, an NMDA receptor antagonist, in the treatment of Parkinson's disease
    • Rabey JM, Nissipeanu P, Korczyn AD. Efficacy of memantine, an NMDA receptor antagonist, in the treatment of Parkinson's disease. J Neural Trans 1992; 4: 277-282.
    • (1992) J Neural Trans , vol.4 , pp. 277-282
    • Rabey, J.M.1    Nissipeanu, P.2    Korczyn, A.D.3
  • 40
    • 0026709480 scopus 로고
    • The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation
    • Ren K, Hylden JLK, Williams GM, Ruda MA, Dubner R. The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain 1992; 50: 331-344.
    • (1992) Pain , vol.50 , pp. 331-344
    • Ren, K.1    Hylden, J.L.K.2    Williams, G.M.3    Ruda, M.A.4    Dubner, R.5
  • 41
    • 0014072270 scopus 로고
    • Causalgia
    • Richards RL. Causalgia. Arch Neurol 1967; 16: 339-350.
    • (1967) Arch Neurol , vol.16 , pp. 339-350
    • Richards, R.L.1
  • 42
    • 0027440588 scopus 로고
    • Spinal cord amino acid release and content in an arthritis model: The effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists
    • Sluka KA, Westlund KN. Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists. Brain Res 1993; 627: 89-103.
    • (1993) Brain Res , vol.627 , pp. 89-103
    • Sluka, K.A.1    Westlund, K.N.2
  • 43
    • 0027176450 scopus 로고
    • Ketamine hydrochloride in the treatment of phantom limb pain
    • Stannard CF, Porter GE. Ketamine hydrochloride in the treatment of phantom limb pain. Pain 1993; 54: 227-230.
    • (1993) Pain , vol.54 , pp. 227-230
    • Stannard, C.F.1    Porter, G.E.2
  • 44
    • 0027210790 scopus 로고
    • Dextrorphan relieves neuropathic heatevoked hyperalgesia in the rat
    • Tal M, Bennett GJ. Dextrorphan relieves neuropathic heatevoked hyperalgesia in the rat. Neurosci Lett 1993; 151: 107-110.
    • (1993) Neurosci Lett , vol.151 , pp. 107-110
    • Tal, M.1    Bennett, G.J.2
  • 45
    • 0019950936 scopus 로고
    • Distribution of memantine in brain, liver, and blood of the rat
    • Wesemann W, Schollmeyer JD, Sturm G. Distribution of memantine in brain, liver, and blood of the rat. Arzneim-Forschl Drug Res 1982; 32: 1243-1245.
    • (1982) Arzneim-Forschl Drug Res , vol.32 , pp. 1243-1245
    • Wesemann, W.1    Schollmeyer, J.D.2    Sturm, G.3
  • 46
    • 0021323340 scopus 로고
    • An instrument using a multiple layer peltier device to change skin temperature rapidly
    • Wilcox GL, Giesler GJ. An instrument using a multiple layer peltier device to change skin temperature rapidly. Brain Res Bull 1984; 12: 143-146.
    • (1984) Brain Res Bull , vol.12 , pp. 143-146
    • Wilcox, G.L.1    Giesler, G.J.2
  • 48
    • 0025974775 scopus 로고
    • The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartate acid receptor activation; implications for treatment of post-injury pain hypersensitivity states
    • Woolf CJ, Thompson SWN. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartate acid receptor activation; implications for treatment of post-injury pain hypersensitivity states. Pain 1991; 44: 293-299.
    • (1991) Pain , vol.44 , pp. 293-299
    • Woolf, C.J.1    Thompson, S.W.N.2
  • 49
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in consious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in consious animals. Pain 1983; 16: 109-110.
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1


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