Central sensitization in tension-type headache - Possible pathophysiological mechanisms

Cephalalgia

Volumn 20, Issue 5, 2000, Pages 486-508

  Bendtsen, L ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Central sensitization; Pathophysiology; Tenderness; Tension type headache; Thesis

Indexed keywords

AMITRIPTYLINE; CITALOPRAM;

FIBROMYALGIA; HUMAN; MYOFASCIAL PAIN; NOCICEPTION; PAIN THRESHOLD; PALPATION; REVIEW; SCORING SYSTEM; SENSITIZATION; SPINAL CORD DORSAL HORN; TENSION HEADACHE; TRIGEMINAL NUCLEUS;

CENTRAL NERVOUS SYSTEM; EQUIPMENT DESIGN; HUMANS; MODELS, NEUROLOGICAL; MYOFASCIAL PAIN SYNDROMES; PAIN THRESHOLD; PALPATION; SEROTONIN; STRESS, PSYCHOLOGICAL; TENSION-TYPE HEADACHE;

EID: 0034454553     PISSN: 03331024     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1468-2982.2000.00070.x     Document Type: Review

References (193)

1. Epidemiology of headache in a general population - A prevalence study
2. Impact of headache on sickness absence and utilisation of medical services: A Danish population study
3. Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain
4. Pericranial tenderness in tension headache. A blind, controlled study
5. Muscle tenderness and pressure pain thresholds in headache. A population study
6. Observations on referred pain arising from muscle
7. Mechanisms of tension headache. A speculative hypothesis
8. Quantification of tenderness by palpation and use of pressure algometers
9. Pressure pain thresholds and thermal nociceptive thresholds in chronic tension-type headache
10. Clinical and pathophysiological observations in migraine and tension-type headache explained by integration of vascular, supraspinal and myofascial inputs
11. Cephalic and extracephalic pressure pain thresholds in chronic tension-type headache
12. Evidence for a central component of post-injury pain hypersensitivity
13. Muscle palpation with controlled finger pressure: New equipment for the study of tender myofascial tissues
14. Pressure-controlled palpation: A new technique which increases the reliability of manual palpation
15. Qualitatively altered nociception in chronic myofascial pain
16. Decreased pain detection and tolerance thresholds in chronic tension-type headache
17. A non-selective (amitripty-line), but not a selective (citalopram), serotonin reuptake inhibitor is effective in the prophylactic treatment of chronic tension-type headache
18. Serotonin metabolism in chronic tension-type headache
19. The platelet serotonin transporter in primary headaches
20. Evidence of a qualitatively altered nociception in patients with fibromyalgia
21. Intra- and interobserver variability in the assessment of signs of disorder in the stomatognathic system
22. Repeatability of measurement of tenderness in the neck-shoulder region by a dolorimeter and manual palpation
23. Interrater reliability of the tender point criterion for fibromyalgia
24. Reliability of a craniomandibular index
25. Are tender point scores assessed by manual palpation in fibromyalgia reliable? An investigation into the variance of tender point scores
26. The reliability of examination for tenderness in patients with myofascial pain, chronic fibromyalgia and controls
27. Cephalic muscle tenderness and pressure pain threshold in a general population
28. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee
29. An electronic method for measuring joint tenderness in rheumatoid arthritis
30. The validation of visual analogue scales as ratio scale measures for chronic and experimental pain
31. Initiating mechanisms of experimentally induced tension-type headache
32. Pericranial muscle tenderness and exteroceptive suppression of temporalis muscle activity: A blind study of chronic tension-type headache
33. Evaluation of pericranial tenderness and oral function in patients with common migraine, muscle contraction headache and 'combination headache'
34. Scalp tenderness and sensitivity to pain in migraine and tension headache
35. Muscle tenderness in tension headache treated with acupuncture or physiotherapy
36. The use of electromyography and muscle palpation in the diagnosis of tension-type headache with and without pericranial muscle involvement
37. Central and peripheral mechanisms in chronic tension-type headache
38. Muscle hardness in patients with chronic tension-type headache: Relation to actual headache state
39. Muscular factors are of importance in tension-type headache
40. Muscular disorders in tension-type headache
41. Pericranial muscle tenderness and pressure-pain threshold in the temporal region during common migraine
42. Signs and symptoms of mandibular dysfunction after introduction of experimental balancing-side interferences
43. Experimental toothclenching in common migraine
44. Skeletal muscle pain
45. Peripheral mechanisms of muscle nociception and local muscle pain
46. Classification of headache
47. Multiple clinical and paraclinical analyses of chronic tension-type headache associated or unassociated with disorder of pericranial muscles
48. A naturalistic study of the relationships among electromyographic activity, psychological stress, and pain in ambulatory tension-type headache patients and headache-free controls
49. Pain sensitivity and pain reactivity of pericranial muscles in migraine and tension-type headache
50. Neurophysiology
51. Quantitative surface EMG of pericranial muscles in headache. A population study
52. Comparative study with EMG, pressure algometry and manual palpation in tension-type headache and migraine
53. Cross-correlation between stress, pain, physical activity, and temporalis muscle EMG in tension-type headache
54. Mechanisms of spontaneous tension-type headaches: An analysis of tenderness, pain thresholds and EMG
55. The pain-adaptation model: A discussion of the relationship between chronic musculoskeletal pain and motor activity
56. Myofascial trigger points show spontaneous needle EMG activity
57. Morphologic, physiologic, and biochemical changes in tender and painful muscle
58. Temporal muscle blood flow in chronic tension-type headache
59. Pericranial muscle hardness in tension-type headache. A non-invasive measurement method and its clinical application
60. Non-invasive measurement method for hardness in muscular tissues
61. Nociception from skeletal muscle in relation to clinical muscle pain
62. Sensitization of peripheral nocisensors in muscle
63. Bradykinin-induced modulation of the response behaviour of different types of feline group III and IV muscle receptors
64. Pain and tenderness in human temporal muscle induced by bradykinin and 5-hydroxytryptamine
65. Muscle pain syndromes - Part II
66. Myofascial mechanisms of pain
67. Neurobiology of the myofascial trigger point
68. Research in fibromyalgia and myofascial pain syndromes: Current status, problems and future directions
69. Lack of association between fibromyalgia syndrome and abnormalities in muscle energy metabolism
70. Migraine and tension-type headache in a general population: Precipitating factors, female hormones, sleep pattern and relation to lifestyle
71. Triggers of headache episodes and coping responses of headache diagnostic groups
72. A comparison of tension-type headache in migraineurs and in non-migraineurs: A population-based study
73. Psychophysiological correlates of induced headaches
74. Cephalic blood flow correlates of induced headaches
75. Psychological and behavioral techniques
76. Central nervous system mechanisms of pain modulation
77. Pain and psychological medicine
78. Psychological aspects
79. Exteroceptive suppression of temporalis muscle activity in chronic headache
80. Exteroceptive suppression and motor control of the masseter and temporalis muscles in normal man
81. Recovery cycle of the masseter inhibitory reflex in man
82. Intracellular responses of raphe magnus neurons during the jaw-opening reflex evoked by tooth pulp stimulation
83. Topodiagnostic value of brain stem reflexes
84. Exteroceptive suppression of the masseter, temporalis and trapezius muscles produced by mental nerve stimulation in patients with chronic headaches
85. EMG analysis of the late exteroceptive suppression period of temporal muscle activity in episodic and chronic tension-type headaches
86. The masseter muscle: The silent period and its clinical implications
87. Reflexes elicitable in jaw muscles and their role during jaw function and dysfunction: A review of the literature. Part III. Reflexes in human jaw muscles during function and dysfunction of the masticatory system
88. Human factors in the measurement of the masseteric silent period
89. Wolff Award 1992. Exteroceptive suppression of temporalis muscle activity in patients with chronic headache and in normal volunteers: Methodology, clinical and pathophysiological relevance
90. Exteroceptive suppression periods in jaw-closing muscles. Variability and relation to experimental pain and sustained muscle contraction
91. Exteroceptive suppression of temporal muscle activity is normal in patients with chronic tension-type headache and not related to actual headache state
92. Exteroceptive suppression of temporalis muscle activity: A blind study of tension-type headache, migraine, and cervicogenic headache
93. Amitriptyline, a combined serotonin and noradrenaline re-uptake inhibitor, reduces exteroceptive suppression of temporal muscle activity in patients with chronic tension-type headache
94. Acetylsalicylic acid activates antinociceptive brain-stem reflex activity in headache patients and in healthy subjects
95. Reduction of temporalis exteroceptive suppression by peripheral electrical stimulation in migraine and tension-type headaches
96. Cervicogenic headache, migraine, and tension-type headache. Pressure-pain threshold measurements
97. Evaluation of pericranial myofascial nociception by pressure algometry. Reproducibility and factors of variation
98. Methods of testing pain mechanisms in normal man
99. Decreased nociceptive flexion reflex threshold in chronic tension-type headache
100. Response properties and descending control of rat dorsal horn neurons with deep receptive fields
101. Visceral nociceptors: A new world order?
102. Central hyperexcitability triggered by noxious inputs
103. Basic and clinical aspects of visceral hyperalgesia
104. Myositis-induced functional reorganisation of the rat dorsal horn: Effects of spinal superfusion with antagonists to neurokinin and glutamate receptors
105. Stimulation of craniofacial muscle afferents induces prolonged facilitatory effects in trigeminal nociceptive brain-stem neurones
106. Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans
107. Quantitative comparison of inhibition of visceral and cutaneous spinal nociceptive transmission from the midbrain and medulla in the rat
108. The nociceptor sensitization by bradykinin does not depend on sympathetic neurons
109. Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat
110. Clinical characterization of patients with chronic tension headache
111. 5-Hydroxytryptamine in nociception and antinociception
112. Serotonin and pain
113. The dorsal raphe: An important nucleus in pain modulation
114. The role of 5-hydroxytryptamine (5-HT) receptor subtypes and plasticity in the 5-HT systems in the regulation of nociceptive sensitivity
115. Serotonin and pain: Evidence that activation of 5-HT1A receptors does not elicit antinociception against noxious thermal, mechanical and chemical stimuli in mice
116. Treatment of chronic tension headache
117. Chronic tension headache - Treated with amitriptyline - A double-blind study
118. Chronic tension-type headache: Amitriptyline reduces clinical headache-duration and experimental pain sensitivity but does not alter pericranial muscle activity readings
119. Efficacy and tolerability of amitriptylinoxide in the treatment of chronic tension-type headache: A multi-centre controlled study
120. Amitriptyline potentiates morphine analgesia by a direct action on the central nervous system
121. Selected tricyclic antidepressants in the management of chronic benign pain
122. The analgesic effect of tricyclic antidepressants
123. A role for serotonin and beta-endorphin in the analgesia induced by some tricyclic antidepressant drugs
124. Comparative effects of different uptake inhibitor antidepressants in two pain tests in mice
125. A comparative trial of amitriptyline and zimelidine in post-herpetic neuralgia
126. The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms
127. Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy
128. Neurochemical characterization of a new potent and selective serotonin uptake inhibitor: Lu 10-171
129. Potentiation of morphine antinociception by monoamine reuptake inhibitors in the rat spinal cord
130. Citalopram - Pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity
131. Tricyclic antidepressants: Therapeutic properties and affinity for alpha-noradrenergic receptor binding sites in the brain
132. Clomipramine vs desipramine vs placebo in the treatment of diabetic neuropathy symptoms. A double-blind cross-over study
133. Antinociceptive effects of serotonergic reuptake inhibitors in mice
134. Reversal of the antinociceptive effects of intrathecally administered serotonin in the rat by a selective 5-HT3 receptor antagonist
135. The 5-HT1-like agonist sumatriptan has a significant effect in chronic tension-type headache
136. Sumatriptan has no clinically relevant effect in the treatment of episodic tension-type headache
137. Participation of opioid and monoaminergic mechanisms on the antinociceptive effect induced by tricyclic antidepressants in two behavioural pain tests in mice
138. Increased cerebrospinal fluid Met-enkephalin immunoreactivity in patients with chronic tension-type headache
139. Plasma and cerebrospinal fluid beta-endorphin in chronic tension-type headache
140. Tricyclic antidepressants block NMDA receptor-mediated synaptic responses and induction of long-term potentiation in rat hippocampal slices
141. Tricyclic antidepressants block N-methyl-D-aspartate receptors: Similarities to the action of zinc
142. Intrathecal amitriptyline acts as an N-methyl-D-aspartate receptor antagonist in the presence of inflammatory hyperalgesia in rats
143. Platelets as pharmacologic models for the receptors and biochemistry of monoaminergic neurons
144. Serotonin, migraine and platelets
145. On serotonin and migraine: A clinical and pharmacological review
146. Biochemistry
147. 5-Hydroxytryptamine in platelets of patients with muscle contraction headache
148. Plasma serotonin in patients with chronic tension headaches
149. Alteration of platelet serotonin in patients with chronic tension-type headache during cold pressor test
150. Platelet substance P and 5-hydroxytryptamine in migraine and tension-type headache
151. Serotonin in tension headache
152. Serotonin metabolism in migraine
153. Metabolism and menstrual cycle rhythmicity of serotonin in primary headaches
154. Platelet-rich plasma serotonin levels in tension-type headache and depression
155. Platelet activation in muscle contraction headache and migraine
156. Plasma serotonin increase during episodes of tension-type headache
157. Beta-thromboglobulin - A specific marker of in-vivo platelet release reaction
158. Plasma levels of beta-thromboglobulin and platelet factor 4 as indices of platelet activation in vivo
159. Studies on the serotonin transporter in platelets
160. Blood platelets as models for neurons: Uses and limitations
161. Primary structure of the human platelet serotonin uptake site: Identity with the brain serotonin transporter
162. Impulsive aggression in personality disorder correlates with tritiated paroxetine binding in the platelet
163. Platelet 3H-imipramine binding and sulphotransferase activity in primary headache
164. Platelet [3H]imipramine binding in migraine and tension headache in relation to depression
165. Why some depressed patients may have low platelet 3H-imipramine binding
166. [3H]imipramine binding in idiopathic pain syndromes. Basal values and changes after treatment with antidepressants
167. Kinetics of platelet 5-hydroxytryptamine uptake in headache patients
168. The pathophysiology of chronic pain - Increased sensitivity to low threshold A beta-fibre inputs
169. Central pharmacology of nociceptive transmission
170. Contribution of central neuroplasticity to pathological pain: Review of clinical and experimental evidence
171. Nitric oxide (NO) and nociceptive processing in the spinal cord
172. Windup and central sensitization are not equivalent
173. Pharmacology of pain transmission and control
174. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states
175. Peripheral nerve injury triggers central sprouting of myelinated afferents
176. Mechanisms of touch-evoked pain (allodynia): A new model
177. Altered properties and laminar distribution of neuronal responses to peripheral stimulation in the SmI cortex of the arthritic rat
178. The effect of peripheral nerve injury on dorsal root potentials and on transmission of afferent signals into the spinal cord
179. Chronic muscular pain: Aetiology and pathogenesis
180. Cervical muscle myoelectric response to acute experimental sternocleidomastoid pain
181. In vivo model of muscle pain: Quantification of intramuscular chemical, electrical, and pressure changes associated with salineinduced muscle pain in humans
182. Experimental models of tension-type headache
183. Increased familial risk of chronic tension-type headache
184. Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: Implications for the treatment of mechanical allodynia
185. The effect of N-methyl-D-aspartate antagonist (ketamine) on single and repeated nociceptive stimuli: A placebo-controlled experimental human study
186. Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine
187. Nitric oxide as a chemical link in the generation of pain from veins in humans
188. Towards a model of pathophysiology of fibromyalgia: Aberrant central pain mechanisms with peripheral modulation
189. Sensory dysfunction in fibromyalgia patients with implications for pathogenic mechanisms
190. Characterisation of capsaicin-induced mechanical hyperalgesia as a marker for altered nociceptive processing in patients with rheumatoid arthritis