LPS-induced MCP-1 expression in human microvascular endothelial cells is mediated by the tyrosine kinase, Pyk2 via the p38 MAPK/NF-κB-dependent pathway

Molecular Immunology

Volumn 46, Issue 5, 2009, Pages 962-968

  Anand, Appakkudal R ^a   Bradley, Ritu ^b   Ganju, Ramesh K ^a  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Endothelial cells; Lipopolysaccharide LPS; Monocyte chemotactic protein MCP 1; Proline rich kinase 2 Pyk2

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; FOCAL ADHESION KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; MUTANT PROTEIN; SMALL INTERFERING RNA; TYRPHOSTIN;

ARTICLE; CATALYSIS; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; LEUKOCYTE MIGRATION INHIBITION; MICROVASCULATURE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; PROTEINASE INHIBITION; SUPERNATANT;

CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CCL2; ENDOTHELIAL CELLS; ENZYME ACTIVATION; ENZYME INHIBITORS; FOCAL ADHESION KINASE 2; GENE EXPRESSION REGULATION; HUMANS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MONOCYTES; MUTATION; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SEPSIS; TYRPHOSTINS;

BACTERIA (MICROORGANISMS);

EID: 59249099787     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.09.022     Document Type: Article

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