Contribution of electrostatic and structural properties of Kv4.3 S4 arginine residues to the regulation of channel gating

Biochimica et Biophysica Acta - Biomembranes

Volumn 1788, Issue 2, 2009, Pages 458-469

  Skerritt, Matthew R ^a   Campbell, Donald L ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Closed state inactivation; Gating; Kv4.3; Recovery; S4 domain

Indexed keywords

ARGININE; KV4.3 S4 ARGININE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ELECTRICITY; ELECTROPHYSIOLOGY; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; ARGININE; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; FERRETS; ION CHANNEL GATING; KINETICS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OOCYTES; PATCH-CLAMP TECHNIQUES; SHAL POTASSIUM CHANNELS; STATIC ELECTRICITY; XENOPUS LAEVIS;

EID: 59249098141     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2008.09.012     Document Type: Article

References (51)

1. Birnbaum S.G., Varga A.W., Yuan L.-Y., Andersen A.E., Sweatt J.D., and Schrader L.A. Structure and function of Kv4-family transient potassium channels. Physiol. Rev. 84 (2004) 803-833
2. Jerng H.H., Pfaffinger P.J., and Covarrubias M. Molecular physiology and modulation of somatodendritic A-type potassium channels. Mol. Cell. Neurosci. 27 (2004) 343-369
3. to", phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms. J. Physiol. 569 (2005) 7-39
4. A in play. Neuron 54 (2007) 850-852
5. +channel subunit Kv4.2 in hippocampal neurons. Neuron 54 (2007) 933-947
6. Hu H.-J., Carrasquillo Y., Karim F., Jung W.E., Nerbonne J.M., Schwarz T.L., and Gereau R.W. The Kv4.2 potassium channel subunit is required for pain plasticity. Neuron 50 (2006) 89-100
7. to). J. Physiol. 546 (2003) 5-18
8. Bahring R., Boland L.M., Vargese A., Gebauer M., and Pongs O. Kinetic analysis of open-and closed-state inactivation transitions in human Kv4.2 A-type potassium channels. J. Physiol. 535 (2001) 65-81
9. Amadi C.C., Brust R.D., Skerritt M.R., and Campbell D.L. Regulation of Kv4.3 closed state inactivation and recovery by extracellular potassium and intracellular KChIP2b. Channels 1 (2007) 305-314
10. Aldrich R.W. Fifty years of inactivation. Nature 411 (2001) 643-644
11. Zhou M., Morals-Cabral J.H., Mann S., and MacKinnon R. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature 411 (2001) 657-661
12. Bezanilla F. The voltage-sensor in voltage-dependent ion channels. Physiol. Rev. 80 (2000) 555-592
13. Bezanilla F. Voltage-gated ion channels. IEEE Trans. Nanobiosci. 1 (2005) 34-48
14. Bezanilla F. How membrane proteins sense voltage. Nature Rev. Mol. Cell. Biol. 9 (2008) 323-332
15. Tombola F., Pathak M.M., and Isacoff E.Y. How does voltage open an ion channel?. Ann. Rev. Cell. Dev. Biol. 22 (2006) 23-52
16. Chanda B., and Bezanilla F. A common pathway for charge transport through voltage-sensing domains. Neuron 57 (2008) 345-351
17. +channel. Neuron 16 (1996) 1169-1177
18. +channel. Neuron 16 (1996) 1159-1167
19. o dependence. J. Physiol. 557 (2004) 705-712
20. Patel S.P., Parai R., Parai R., and Campbell D.L. Regulation of Kv4.3 voltage-dependent gating kinetics by KChIP2 isoforms. J. Physiol. 557 (2004) 19-41
21. Skerritt M.R., and Campbell D.L. Role of S4 positively charged residues in the regulation of Kv4.3 inactivation and recovery. Am. J. Physiol. Cell. Physiol. 293 (2007) C906-C914
22. Sigworth F.J. Voltage gating of ion channels. Quart. Rev. Biophys. 27 (1994) 1-40
23. Yellen G. The moving parts of voltage-gated ion channels. Quart. Rev. Biophys. 31 (1998) 239-295
24. Hille B. Gating: Voltage sensing and inactivation. Ion Channels of Excitable Membranes. 3rd Edition (2001), Sinauer Associates, Sunderland, MA 603-634
25. Jackson M.B. Global transitions in proteins. Molecular and Cellular Biophysics (2006), Cambridge University Press, Cambridge, UK 1-24
26. Papazian D.M., Timpe L.C., Jan Y.N., and Jan L.Y. Alteration of voltage dependence of Shaker potassium channel by mutations in the S4 sequence. Nature 349 (1991) 305-310
27. Zamyatnin A.A. Amino acid, peptide, and protein volume in solution. Ann. Rev. Biophys. Bioeng. 13 (1984) 145-165
28. Kyte J., and Doolittle R.F. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157 (1982) 105-132
29. Engelman D.M., Steitz T.A., and Goldman A. Identifying nonpolar transmembrane helices in amino acid sequences of membrane proteins. Ann. Rev. Biophys. Biophys. Chem. 15 (1986) 321-353
30. Starace D.M., and Bezanilla F. A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature 427 (2004) 548-553
31. Asamoah O.K., Wuskell J.P., Loew L.M., and Bezanilla F. A fluorometric approach to local electric field measurements in a voltage-gated ion channel. Neuron 37 (2003) 85-97
32. Ahern C.A., and Horn R. Focused electric field across the voltage sensor of potassium channels. Neuron 48 (2005) 25-29
33. Tombola F., Pathak M.M., and Isacoff E.Y. Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores. Neuron 45 (2005) 379-388
34. Campos F.V., Chanda B., Roux B., and Bezanilla F. Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel. Proc. Nat. Acad. Sci. 104 (2007) 7904-7909
35. Tombola F., Pathak M.M., Gorostiza P., and Isacoff E.Y. The twisted ion-permeation pathway of a resting voltage-sensing domain. Nature 445 (2007) 546-549
36. + channel. Neuron 56 (2007) 124-140
37. Patel S.P., Campbell D.L., Morales M.J., and Strauss H.C. Heterogeneous expression of KChIP2 isoforms in the ferret heart. J. Physiol. 539 (2002) 649-656
38. Campbell D.L., Rasmusson R.L., Qu Y., and Strauss H.C. The calcium-independent potassium current in isolated ferret right ventricular myocytes. I. Basic characterization and kinetic analysis. J. Gen. Physiol. 101 (1993) 571-601
39. +channel-interacting protein 2. J. Biol. Chem. 279 (2004) 5549-5554
40. Dougherty K., and Covarrubias M. A dipeptidyl aminopeptidase-like protein remodels gating charge dynamics in Kv4.2 channels. J. Gen. Physiol. 128 (2006) 745-753
41. Dougherty K., De Santiago-Castillo J.A., and Covarrubias M. Gating charge imobilization in Kv4.2 channels: The basis of closed-state inactivation. J. Gen. Physiol. 131 (2008) 257-273
42. Hodgkin A.L., and Huxley A.F. A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117 (1952) 500-544
43. Stefani E., and Bezanilla F. Cut-open oocyte voltage-clamp technique. Methods Enzymol. 293 (1998) 300-318
44. Wang S., Bondarenko V.E., Qu Y.-J., Bett G.C., Morales M.J., Rasmusson R.L., and Strauss H.C. Time-and voltage-dependent components of Kv4.3 inactivation. Biophys. J. 89 (2005) 3026-3041
45. Catterall W.A. Molecular properties of voltage-sensitive sodium channels. Ann. Rev. Biochem. 55 (1986) 953-985
46. + channel. Science 309 (2005) 897-903
47. Long S.B., Campbell E.B., and MacKinnon R. Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science 309 (2005) 903-908
48. Parsegian A. Energy of an ion crossing a low dielectric membrane: Solutions to four relevant electrostatic problems. Nature 221 (1969) 844-846
49. Li L., Vorobyov I., MacKerell A.D., and Allen T.W. Is arginine charged in a membrane?. Biophys. J. 94 (2008) L11-L13
50. + channel in a lipid membrane-like environment. Nature 450 (2007) 376-383
51. + channels. J. Physiol. 582 (2007) 1059-1072