Pruritus in hemodialysis patients: The problem remains

Hemodialysis International

Volumn 13, Issue 1, 2009, Pages 38-42

  Melo, Natalia C V ^a,b   Elias, Rosilene M ^a   Castro, Manuel Carlos M ^a   Romao, Joao E ^a   Abensur, Hugo ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE   (Brazil)

Author keywords

End stage renal disease; Hemodialysis; Inflammation; Pruritus

Indexed keywords

ALPHA1 GLYCOPROTEIN; C REACTIVE PROTEIN; HEPCIDIN; TRANSFERRIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; INFLAMMATION; IRON DEFICIENCY; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRURITUS; UPREGULATION; UREMIA;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BETA 2-MICROGLOBULIN; C-REACTIVE PROTEIN; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; OROSOMUCOID; PREVALENCE; PRURITUS; RENAL DIALYSIS;

EID: 59249089304     PISSN: 14927535     EISSN: 15424758     Source Type: Journal    
DOI: 10.1111/j.1542-4758.2009.00346.x     Document Type: Article

References (18)

1. Narita I, Alchi B, Omori K, et al. Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patients. Kidney Int. 2006; 69: 1626-1632.
2. Patel TS, Freedman BI, Yosipovitch G. An update on pruritus associated with CKD. Am J Kidney Dis. 2007; 50: 11-20.
3. Zucker I, Yosipovitch G, David M, Gafter U, Boner G. Prevalence and characterization of uremic pruritus in patients undergoing hemodialysis: Uremic pruritus is still a major problem for patients with end-stage renal disease. J Am Acad Dermatol. 2003; 49: 842-846.
4. Mistik S, Utas S, Ferahbas A, et al. An epidemiology study of patients with uremic pruritus. J Eur Acad Dermatol Venereol. 2006; 20: 672-678.
5. Kimmel M, Alscher DM, Dunst R, et al. The role of micro-inflammation in the pathogenesis of uremic pruritus in hemodialysis patients. Nephrol Dial Transplant. 2006; 21: 749-755.
6. Virga G, Visentin I, La Milia V, Bonadonna A. Inflammation and pruritus in hemodialysis patients. Nephrol Dial Transplant. 2002; 17: 2164-2169.
7. National Kidney Foundation. KDOQI clinical practical guidelines for hemodialysis adequacy. Am J Kidney Dis. 1997; 30(Suppl): S15-S66.
8. Sato S. Iron deficiency: Structural and microchemical changes in hair nails, and skin. Semin Dermatol. 1991; 10: 313-319.
9. Andrews NC. Anemia of inflammation: The cytokine-hepcidin link. J Clin Invest. 2004; 113: 1251-1253.
10. Meydani SN, Wu D. Age-associated inflammatory changes: Role of nutritional intervention. Nutr Rev. 2007; 65: S213-S216.
11. Wu D, Meydani SN. Mechanism of age-associated up-regulation in macrophage PGE2 synthesis. Brain Behav Immun. 2004; 18: 487-494.
12. Keithi-Reddy SR, Patel TV, Armstrong AW, Singh AK. Uremic pruritus. Kidney Int. 2007; 72: 373-377.
13. Chen YC, Chiu WT, Wu MS. Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. Am J Kidney Dis. 2006; 48: 69-76.
14. Seckin D, Demircay Z, Akin O. Generalized pruritus treated with narrowband UVB. Int J Dermatol. 2007; 46: 367-370.
15. Rivard J, Lim HW. Ultraviolet phototherapy for pruritus. Dermatol Ther. 2005; 18: 344-354.
16. Pauli-Magnus C, Klumpp S, Alscher DM, et al. Short-term efficacy of tacrolimus ointment in severe uremic pruritus. Perit Dial Int. 2000; 20: 802-803.
17. Silva SR, Viana PC, Lugon NV, et al. Thalidomide for the treatment of uremic pruritus: A crossover randomized double-blind trial. Nephron. 1994; 67: 270-273.
18. Altmeyer P, Kachel HG, Schafer G, et al. Normalization of uremic skin changes following kidney transplantation. Hautarzt. 1986; 37: 217-222.