-
1
-
-
0029976817
-
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
-
Beg AA and Baltimore D (1996) An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274:782-784.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
2
-
-
26444468146
-
Mitochondria: Pharmacological manipulation of cell death
-
Bouchier-Hayes L, Lartigue L, and Newmeyer DD (2005) Mitochondria: pharmacological manipulation of cell death. J Clin Invest 115:2640-2647.
-
(2005)
J Clin Invest
, vol.115
, pp. 2640-2647
-
-
Bouchier-Hayes, L.1
Lartigue, L.2
Newmeyer, D.D.3
-
4
-
-
14644407525
-
The role of apoptosis in cancer development and treatment response
-
Brown JM and Attardi LD (2005) The role of apoptosis in cancer development and treatment response. Nat Rev Cancer 5:231-237.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 231-237
-
-
Brown, J.M.1
Attardi, L.D.2
-
5
-
-
1542472979
-
Apoptosis genes and resistance to cancer therapy: What does the experimental and clinical data tell us?
-
Brown JM and Wilson G (2003) Apoptosis genes and resistance to cancer therapy: what does the experimental and clinical data tell us? Cancer Biol Ther 2:477-490.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 477-490
-
-
Brown, J.M.1
Wilson, G.2
-
6
-
-
0035476242
-
Induction of apoptosis in 9-nitrocamptothecin- treated DU145 human prostate carcinoma cells correlates with de novo synthesis of CD95 and CD95 ligand and down-regulation of c-FLIP(short)
-
Chatterjee D, Schmitz I, Krueger A, Yeung K, Kirchhoff S, Krammer PH, Peter ME, Wyche JH, and Pantazis P (2001) Induction of apoptosis in 9-nitrocamptothecin- treated DU145 human prostate carcinoma cells correlates with de novo synthesis of CD95 and CD95 ligand and down-regulation of c-FLIP(short). Cancer Res 61:7148-7154.
-
(2001)
Cancer Res
, vol.61
, pp. 7148-7154
-
-
Chatterjee, D.1
Schmitz, I.2
Krueger, A.3
Yeung, K.4
Kirchhoff, S.5
Krammer, P.H.6
Peter, M.E.7
Wyche, J.H.8
Pantazis, P.9
-
7
-
-
0344925540
-
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
-
Chipuk JE, Maurer U, Green DR, and Schuler M (2003) Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription. Cancer Cell 4:371-381.
-
(2003)
Cancer Cell
, vol.4
, pp. 371-381
-
-
Chipuk, J.E.1
Maurer, U.2
Green, D.R.3
Schuler, M.4
-
8
-
-
0016240205
-
Biological effects of 5-azacytidine in eukaryotes
-
Cihak A (1974) Biological effects of 5-azacytidine in eukaryotes. Oncology 30:405-422.
-
(1974)
Oncology
, vol.30
, pp. 405-422
-
-
Cihak, A.1
-
10
-
-
0842281645
-
Cell death: Critical control points
-
Danial NN and Korsmeyer SJ (2004) Cell death: critical control points. Cell 116: 205-219.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
11
-
-
34249810007
-
Activation of an alternative death receptor-induced signaling pathway in human hepatocytes under caspase arrest
-
Dünstl G, Weiland T, Schlaeger C, Nüssler A, Kunstle G, and Wendel A (2007) Activation of an alternative death receptor-induced signaling pathway in human hepatocytes under caspase arrest. Arch Biochem Biophys 462:140-149.
-
(2007)
Arch Biochem Biophys
, vol.462
, pp. 140-149
-
-
Dünstl, G.1
Weiland, T.2
Schlaeger, C.3
Nüssler, A.4
Kunstle, G.5
Wendel, A.6
-
12
-
-
0141893341
-
Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions
-
Egger L, Schneider J, Rhême C, Tapernoux M, Häcki J, and Borner C (2003) Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions. Cell Death Differ 10:1188-1203.
-
(2003)
Cell Death Differ
, vol.10
, pp. 1188-1203
-
-
Egger, L.1
Schneider, J.2
Rhême, C.3
Tapernoux, M.4
Häcki, J.5
Borner, C.6
-
13
-
-
29244477848
-
Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction
-
Eramo A, Pallini R, Lotti F, Sette G, Patti M, Bartucci M, Ricci-Vitiani L, Signore M, Stassi G, Larocca LM, et al. (2005) Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction. Cancer Res 65:11469-11477.
-
(2005)
Cancer Res
, vol.65
, pp. 11469-11477
-
-
Eramo, A.1
Pallini, R.2
Lotti, F.3
Sette, G.4
Patti, M.5
Bartucci, M.6
Ricci-Vitiani, L.7
Signore, M.8
Stassi, G.9
Larocca, L.M.10
-
14
-
-
0029935682
-
Involvement ofthe CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen C, Herr I, Krammer PH, and Debatin KM (1996) Involvement ofthe CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 2:574-577.
-
(1996)
Nat Med
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
15
-
-
33747841204
-
5-Aza-2′-deoxycytidine and IFN-gamma cooperate to sensitize for TRAIL-induced apoptosis by upregulating caspase-8
-
Fulda S and Debatin KM (2006a) 5-Aza-2′-deoxycytidine and IFN-gamma cooperate to sensitize for TRAIL-induced apoptosis by upregulating caspase-8. Oncogene 25:5125-5133.
-
(2006)
Oncogene
, vol.25
, pp. 5125-5133
-
-
Fulda, S.1
Debatin, K.M.2
-
16
-
-
33746886979
-
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
-
Fulda S and Debatin KM (2006b) Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 25:4798-4811.
-
(2006)
Oncogene
, vol.25
, pp. 4798-4811
-
-
Fulda, S.1
Debatin, K.M.2
-
17
-
-
0035008833
-
Evidence that death receptor DR4 is a DNA damage-inducible, p53-regulated gene
-
Guan B, Yue P, and Clayman GL, Sun SY (2001) Evidence that death receptor DR4 is a DNA damage-inducible, p53-regulated gene. J Cell Physiol 188: 98-105.
-
(2001)
J Cell Physiol
, vol.188
, pp. 98-105
-
-
Guan, B.1
Yue, P.2
Clayman, G.L.3
Sun, S.Y.4
-
18
-
-
0015177796
-
5-Azacytidine in childhood leukaemia
-
Hrodek O and Vesely J (1971) 5-Azacytidine in childhood leukaemia. Neoplasma 18:493-503.
-
(1971)
Neoplasma
, vol.18
, pp. 493-503
-
-
Hrodek, O.1
Vesely, J.2
-
19
-
-
0003633755
-
-
Institute of Laboratory Animal Resources , 7th ed, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Academic Press, Washington, DC
-
Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals, 7th ed, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Academic Press, Washington, DC.
-
(1996)
Guide for the Care and Use of Laboratory Animals
-
-
-
20
-
-
0033832629
-
Noncaspase proteases in apoptosis
-
Johnson DE (2000) Noncaspase proteases in apoptosis. Leukemia 14:1695-1703.
-
(2000)
Leukemia
, vol.14
, pp. 1695-1703
-
-
Johnson, D.E.1
-
21
-
-
16244400457
-
FDA drug approval summary: Azacytidine (5-azacytidine, Vidaza) for injectable suspension
-
Kaminskas E, Farrell AT, Wang YC, Sridhara R, and Pazdur R (2005) FDA drug approval summary: azacytidine (5-azacytidine, Vidaza) for injectable suspension. Oncologist 10:176-182.
-
(2005)
Oncologist
, vol.10
, pp. 176-182
-
-
Kaminskas, E.1
Farrell, A.T.2
Wang, Y.C.3
Sridhara, R.4
Pazdur, R.5
-
22
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH, and Currie AR (1972) Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics. Br J Cancer 26:239 -257.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
24
-
-
0030964037
-
ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha
-
Kunstle G, Leist M, Uhlig S, Revesz L, Feifel R, MacKenzie A, and Wendel A (1997) ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha. Immunol Lett 55:5-10.
-
(1997)
Immunol Lett
, vol.55
, pp. 5-10
-
-
Kunstle, G.1
Leist, M.2
Uhlig, S.3
Revesz, L.4
Feifel, R.5
MacKenzie, A.6
Wendel, A.7
-
25
-
-
0027998359
-
Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcrip-tional arrest
-
Leist M, Gantner F, Bohlinger I, Germann PG, Tiegs G, and Wendel A (1994) Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcrip-tional arrest. J Immunol 153:1778-1788.
-
(1994)
J Immunol
, vol.153
, pp. 1778-1788
-
-
Leist, M.1
Gantner, F.2
Bohlinger, I.3
Germann, P.G.4
Tiegs, G.5
Wendel, A.6
-
26
-
-
0035038613
-
Triggering of apoptosis by cathepsins
-
Leist M and Jäättelä M (2001) Triggering of apoptosis by cathepsins. Cell Death Differ 8:324-326.
-
(2001)
Cell Death Differ
, vol.8
, pp. 324-326
-
-
Leist, M.1
Jäättelä, M.2
-
27
-
-
3042589745
-
Serine protease inhibitor 2Ainhibits caspase-independent cell death
-
Liu N, Wang Y, and Ashton-Rickardt PG (2004) Serine protease inhibitor 2Ainhibits caspase-independent cell death. FEBS Lett 569:49-53.
-
(2004)
FEBS Lett
, vol.569
, pp. 49-53
-
-
Liu, N.1
Wang, Y.2
Ashton-Rickardt, P.G.3
-
28
-
-
0041853690
-
Induction ofTNFreceptorI-mediated apoptosis via two sequential signaling complexes
-
MicheauOand TschoppJ(2003) Induction ofTNFreceptorI-mediated apoptosis via two sequential signaling complexes. Cell 114:181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
MicheauOand TschoppJ1
-
30
-
-
0040419494
-
Drug-induced apoptosis in hepatoma cells is mediated by the CD95(APO-1/Fas) receptor/ligand system and involves activation of wild-type p53
-
Müller M, Strand S, Hug H, Heinemann EM, Walczak H, Hofmann WJ, Stremmel W, Krammer PH, and Galle PR (1997) Drug-induced apoptosis in hepatoma cells is mediated by the CD95(APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J Clin Invest 99:403-413.
-
(1997)
J Clin Invest
, vol.99
, pp. 403-413
-
-
Müller, M.1
Strand, S.2
Hug, H.3
Heinemann, E.M.4
Walczak, H.5
Hofmann, W.J.6
Stremmel, W.7
Krammer, P.H.8
Galle, P.R.9
-
31
-
-
34848901341
-
A more serine way to die: Defining the characteristics of serine protease-mediated cell death cascades
-
O'Connell AR and Stenson-Cox C (2007) A more serine way to die: defining the characteristics of serine protease-mediated cell death cascades. Biochim Biophys Acta 1773:1491-1499.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1491-1499
-
-
O'Connell, A.R.1
Stenson-Cox, C.2
-
32
-
-
3242806104
-
Caspases and cancer: Mechanisms of inactivation and new treatment modalities
-
Philchenkov A, Zavelevich M, Kroczak TJ, and Los M (2004) Caspases and cancer: mechanisms of inactivation and new treatment modalities. Exp Oncol 26:82-97.
-
(2004)
Exp Oncol
, vol.26
, pp. 82-97
-
-
Philchenkov, A.1
Zavelevich, M.2
Kroczak, T.J.3
Los, M.4
-
33
-
-
0035799382
-
Changes in DNA methylation in neoplasia: Pathophysiology and therapeutic implications
-
Santini V, Kantarjian HM, and Issa JP (2001) Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. Ann Intern Med 134: 573-586.
-
(2001)
Ann Intern Med
, vol.134
, pp. 573-586
-
-
Santini, V.1
Kantarjian, H.M.2
Issa, J.P.3
-
34
-
-
0035895056
-
Receptor- and mito-chondrial mediated apoptosis in acute leukemia: A translational view
-
Schimmer AD, Hedley DW, Penn LZ, and Minden MD (2001) Receptor- and mito-chondrial mediated apoptosis in acute leukemia: a translational view. Blood 98: 3541-3553.
-
(2001)
Blood
, vol.98
, Issue.3
, pp. 541-3553
-
-
Schimmer, A.D.1
Hedley, D.W.2
Penn, L.Z.3
Minden, M.D.4
-
35
-
-
0034732258
-
Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site
-
Takimoto R and El-Deiry WS (2001) Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene 19:1735-1743.
-
(2001)
Oncogene
, vol.19
, pp. 1735-1743
-
-
Takimoto, R.1
El-Deiry, W.S.2
-
36
-
-
0037237988
-
Caspase- and serine protease dependent apoptosis by the death domain of FADD in normal epithelial cells
-
Thorburn J, Bender LM, Morgan MJ, and Thorburn A (2003) Caspase- and serine protease dependent apoptosis by the death domain of FADD in normal epithelial cells. Mol Biol Cell 14:67-77.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 67-77
-
-
Thorburn, J.1
Bender, L.M.2
Morgan, M.J.3
Thorburn, A.4
-
37
-
-
0014733906
-
-
Winkley MWand Robins RK (1970) Direct glycosylation of1,3,5-triazinones. A new approach to the synthesis of the nucleoside antibiotic 5-azacytidine (4-amino-1- beta-D-ribofuranosyl-1,3,5-triazin-2-one) and related derivatives. J Org Chem 35: 491-495.
-
Winkley MWand Robins RK (1970) Direct glycosylation of1,3,5-triazinones. A new approach to the synthesis of the nucleoside antibiotic 5-azacytidine (4-amino-1- beta-D-ribofuranosyl-1,3,5-triazin-2-one) and related derivatives. J Org Chem 35: 491-495.
-
-
-
-
38
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo CB and Jones PA (2006) Epigenetic therapy of cancer: past, present and future. Nat Rev Drug Discov 5:37-50.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
|