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Volumn 10, Issue 1, 2009, Pages 47-55

A lupus-susceptibility C57BL/6 locus on chromosome 3 (Sle18) contributes to autoantibody production in 129 mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; CD2 ANTIGEN; TRANSCRIPTION FACTOR FOXP3;

EID: 59149087296     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2008.78     Document Type: Article
Times cited : (15)

References (43)
  • 1
    • 37349076340 scopus 로고    scopus 로고
    • General aspects of the genetics of SLE
    • Rhodes B, Vyse TJ. General aspects of the genetics of SLE. Autoimmunity 2007; 40: 550-559.
    • (2007) Autoimmunity , vol.40 , pp. 550-559
    • Rhodes, B.1    Vyse, T.J.2
  • 2
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008; 40: 204-210.
    • (2008) Nat Genet , vol.40 , pp. 204-210
    • Harley, J.B.1    Alarcon-Riquelme, M.E.2    Criswell, L.A.3    Jacob, C.O.4    Kimberly, R.P.5    Moser, K.L.6
  • 3
    • 38649138296 scopus 로고    scopus 로고
    • Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus
    • Kozyrev SV, Abelson AK, Wojcik J, Zaghlool A, Linga Reddy MV, Sanchez E et al. Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Nat Genet 2008; 40: 211-216.
    • (2008) Nat Genet , vol.40 , pp. 211-216
    • Kozyrev, S.V.1    Abelson, A.K.2    Wojcik, J.3    Zaghlool, A.4    Linga Reddy, M.V.5    Sanchez, E.6
  • 4
    • 40049108936 scopus 로고    scopus 로고
    • Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
    • Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S et al. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 2008; 358: 900-909.
    • (2008) N Engl J Med , vol.358 , pp. 900-909
    • Hom, G.1    Graham, R.R.2    Modrek, B.3    Taylor, K.E.4    Ortmann, W.5    Garnier, S.6
  • 5
    • 38649108122 scopus 로고    scopus 로고
    • A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus
    • Nath SK, Han S, Kim-Howard X, Kelly JA, Viswanathan P, Gilkeson GS et al. A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. Nat Genet 2008; 40: 152-154.
    • (2008) Nat Genet , vol.40 , pp. 152-154
    • Nath, S.K.1    Han, S.2    Kim-Howard, X.3    Kelly, J.A.4    Viswanathan, P.5    Gilkeson, G.S.6
  • 6
    • 37549016379 scopus 로고    scopus 로고
    • Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus
    • Graham DS, Graham RR, Manku H, Wong AK, Whittaker JC, Gaffney PM et al. Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Nat Genet 2008; 40: 83-89.
    • (2008) Nat Genet , vol.40 , pp. 83-89
    • Graham, D.S.1    Graham, R.R.2    Manku, H.3    Wong, A.K.4    Whittaker, J.C.5    Gaffney, P.M.6
  • 7
    • 0034816964 scopus 로고    scopus 로고
    • Delineating the genetic basis of systemic lupus erythematosus
    • Wakeland EK, Liu K, Graham RR, Behrens TW. Delineating the genetic basis of systemic lupus erythematosus. Immunity 2001; 15: 397-408.
    • (2001) Immunity , vol.15 , pp. 397-408
    • Wakeland, E.K.1    Liu, K.2    Graham, R.R.3    Behrens, T.W.4
  • 8
    • 0035852650 scopus 로고    scopus 로고
    • The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes
    • Morel L, Blenman KR, Croker BP, Wakeland EK. The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. Proc Natl Acad Sci USA 2001; 98: 1787-1792.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1787-1792
    • Morel, L.1    Blenman, K.R.2    Croker, B.P.3    Wakeland, E.K.4
  • 9
    • 19344369383 scopus 로고    scopus 로고
    • Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in genetargeted mice
    • Bygrave AE, Rose KL, Cortes-Hernandez J,Warren J, Rigby RJ, Cook HT et al. Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in genetargeted mice. PLoS Biol 2004; 2: E243.
    • (2004) PLoS Biol , vol.2
    • Bygrave, A.E.1    Rose, K.L.2    Cortes-Hernandez, J.3    Warren, J.4    Rigby, R.J.5    Cook, H.T.6
  • 10
    • 0028942144 scopus 로고
    • Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner
    • Drake CG, Rozzo SJ, Hirschfeld HF, Smarnworawong NP, Palmer E, Kotzin BL. Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner. J Immunol 1995; 154: 2441-2447.
    • (1995) J Immunol , vol.154 , pp. 2441-2447
    • Drake, C.G.1    Rozzo, S.J.2    Hirschfeld, H.F.3    Smarnworawong, N.P.4    Palmer, E.5    Kotzin, B.L.6
  • 11
    • 0031157347 scopus 로고    scopus 로고
    • Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice
    • Vyse TJ, Rozzo SJ, Drake CG, Izui S, Kotzin BL. Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice. J Immunol 1997; 158: 5566-5574.
    • (1997) J Immunol , vol.158 , pp. 5566-5574
    • Vyse, T.J.1    Rozzo, S.J.2    Drake, C.G.3    Izui, S.4    Kotzin, B.L.5
  • 12
    • 10344252778 scopus 로고    scopus 로고
    • Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus
    • Wandstrat AE, Nguyen C, Limaye N, Chan AY, Subramanian S, Tian XH et al. Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus. Immunity 2004; 21: 769-780.
    • (2004) Immunity , vol.21 , pp. 769-780
    • Wandstrat, A.E.1    Nguyen, C.2    Limaye, N.3    Chan, A.Y.4    Subramanian, S.5    Tian, X.H.6
  • 13
    • 33846906478 scopus 로고    scopus 로고
    • Genetic dissection of spontaneous autoimmunity driven by 129-derived chromosome 1 Loci when expressed on C57BL/6 mice
    • Carlucci F, Cortes-Hernandez J, Fossati-Jimack L, Bygrave AE, Walport MJ, Vyse TJ et al. Genetic dissection of spontaneous autoimmunity driven by 129-derived chromosome 1 Loci when expressed on C57BL/6 mice. J Immunol 2007; 178: 2352-2360.
    • (2007) J Immunol , vol.178 , pp. 2352-2360
    • Carlucci, F.1    Cortes-Hernandez, J.2    Fossati-Jimack, L.3    Bygrave, A.E.4    Walport, M.J.5    Vyse, T.J.6
  • 14
    • 0033059667 scopus 로고    scopus 로고
    • Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity
    • Bickerstaff MC, Botto M, Hutchinson WL, Herbert J, Tennent GA, Bybee A et al. Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity. Nat Med 1999; 5: 694-697.
    • (1999) Nat Med , vol.5 , pp. 694-697
    • Bickerstaff, M.C.1    Botto, M.2    Hutchinson, W.L.3    Herbert, J.4    Tennent, G.A.5    Bybee, A.6
  • 15
    • 0033695963 scopus 로고    scopus 로고
    • Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis
    • Bolland S, Ravetch JV. Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis. Immunity 2000; 13: 277-285.
    • (2000) Immunity , vol.13 , pp. 277-285
    • Bolland, S.1    Ravetch, J.V.2
  • 16
    • 0036681645 scopus 로고    scopus 로고
    • A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus
    • Wu X, Jiang N, Deppong C, Singh J, Dolecki G, Mao D et al. A role for the Cr2 gene in modifying autoantibody production in systemic lupus erythematosus. J Immunol 2002; 169: 1587-1592.
    • (2002) J Immunol , vol.169 , pp. 1587-1592
    • Wu, X.1    Jiang, N.2    Deppong, C.3    Singh, J.4    Dolecki, G.5    Mao, D.6
  • 17
    • 0036735306 scopus 로고    scopus 로고
    • Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice
    • Miwa T, Maldonado MA, Zhou L, Sun X, Luo HY, Cai D et al. Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice. Am J Pathol 2002; 161: 1077-1086.
    • (2002) Am J Pathol , vol.161 , pp. 1077-1086
    • Miwa, T.1    Maldonado, M.A.2    Zhou, L.3    Sun, X.4    Luo, H.Y.5    Cai, D.6
  • 18
    • 0038272058 scopus 로고    scopus 로고
    • A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen
    • Xue D, Shi H, Smith JD, Chen X, Noe DA, Cedervall T et al. A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen. Proc Natl Acad Sci USA 2003; 100: 7503-7508.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 7503-7508
    • Xue, D.1    Shi, H.2    Smith, J.D.3    Chen, X.4    Noe, D.A.5    Cedervall, T.6
  • 19
    • 33750308551 scopus 로고    scopus 로고
    • Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus
    • Heidari Y, Bygrave AE, Rigby RJ, Rose KL, Walport MJ, Cook HT et al Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus. Genes Immun 2006; 7: 592-599.
    • (2006) Genes Immun , vol.7 , pp. 592-599
    • Heidari, Y.1    Bygrave, A.E.2    Rigby, R.J.3    Rose, K.L.4    Walport, M.J.5    Cook, H.T.6
  • 20
    • 0037025942 scopus 로고    scopus 로고
    • Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity
    • Shi X, Xie C, Kreska D, Richardson JA, Mohan C. Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity. J Exp Med 2002; 196: 281-292.
    • (2002) J Exp Med , vol.196 , pp. 281-292
    • Shi, X.1    Xie, C.2    Kreska, D.3    Richardson, J.A.4    Mohan, C.5
  • 21
    • 0028324236 scopus 로고
    • Maturational changes in CD4+ cell subsets and lymphokine production in BXSB mice
    • Chu EB, Ernst DN, Hobbs MV, Weigle WO. Maturational changes in CD4+ cell subsets and lymphokine production in BXSB mice. J Immunol 1994; 152: 4129-4138.
    • (1994) J Immunol , vol.152 , pp. 4129-4138
    • Chu, E.B.1    Ernst, D.N.2    Hobbs, M.V.3    Weigle, W.O.4
  • 22
    • 0030039652 scopus 로고    scopus 로고
    • Intervention of CD4+ cell subset shifts and autoimmunity in the BXSB mouse by murine CTLA4Ig
    • Chu EB, Hobbs MV, Wilson CB, Romball CG, Linsley PS, Weigle WO. Intervention of CD4+ cell subset shifts and autoimmunity in the BXSB mouse by murine CTLA4Ig. J Immunol 1996; 156: 1262-1268.
    • (1996) J Immunol , vol.156 , pp. 1262-1268
    • Chu, E.B.1    Hobbs, M.V.2    Wilson, C.B.3    Romball, C.G.4    Linsley, P.S.5    Weigle, W.O.6
  • 23
    • 1342298274 scopus 로고    scopus 로고
    • Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus
    • Croker BP, Gilkeson G, Morel L. Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus. Genes Immun 2003; 4: 575-585.
    • (2003) Genes Immun , vol.4 , pp. 575-585
    • Croker, B.P.1    Gilkeson, G.2    Morel, L.3
  • 24
    • 1242276210 scopus 로고    scopus 로고
    • Deficiency of the cyclin kinase inhibitor p21(WAF-1/CIP-1) promotes apoptosis of activated/memory T cells and inhibits spontaneous systemic autoimmunity
    • Lawson BR, Baccala R, Song J, Croft M, Kono DH, Theofilopoulos AN. Deficiency of the cyclin kinase inhibitor p21(WAF-1/CIP-1) promotes apoptosis of activated/memory T cells and inhibits spontaneous systemic autoimmunity. J Exp Med 2004; 199: 547-557.
    • (2004) J Exp Med , vol.199 , pp. 547-557
    • Lawson, B.R.1    Baccala, R.2    Song, J.3    Croft, M.4    Kono, D.H.5    Theofilopoulos, A.N.6
  • 25
    • 4444291135 scopus 로고    scopus 로고
    • Monocytosis and accelerated activation of lymphocytes in C1q-deficient autoimmune-prone mice
    • Trendelenburg M, Manderson AP, Fossati-Jimack L, Walport MJ, Botto M. Monocytosis and accelerated activation of lymphocytes in C1q-deficient autoimmune-prone mice. Immunology 2004; 113: 80-88.
    • (2004) Immunology , vol.113 , pp. 80-88
    • Trendelenburg, M.1    Manderson, A.P.2    Fossati-Jimack, L.3    Walport, M.J.4    Botto, M.5
  • 27
    • 0037371122 scopus 로고    scopus 로고
    • The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells
    • Amano H, Amano E, Moll T, Marinkovic D, Ibnou-Zekri N, Martinez-Soria E et al. The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells. J Immunol 2003; 170: 2293-2301.
    • (2003) J Immunol , vol.170 , pp. 2293-2301
    • Amano, H.1    Amano, E.2    Moll, T.3    Marinkovic, D.4    Ibnou-Zekri, N.5    Martinez-Soria, E.6
  • 28
    • 0031657151 scopus 로고    scopus 로고
    • Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice
    • Mohan C, Morel L, Yang P, Wakeland EK. Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone mice. Arthritis Rheum 1998; 41: 1652-1662.
    • (1998) Arthritis Rheum , vol.41 , pp. 1652-1662
    • Mohan, C.1    Morel, L.2    Yang, P.3    Wakeland, E.K.4
  • 29
    • 8444240378 scopus 로고    scopus 로고
    • Mechanisms of peritoneal B-1a cells accumulation induced by murine lupus susceptibility locus Sle2
    • Xu Z, Butfiloski EJ, Sobel ES, Morel L. Mechanisms of peritoneal B-1a cells accumulation induced by murine lupus susceptibility locus Sle2. J Immunol 2004; 173: 6050-6058.
    • (2004) J Immunol , vol.173 , pp. 6050-6058
    • Xu, Z.1    Butfiloski, E.J.2    Sobel, E.S.3    Morel, L.4
  • 30
    • 17244378876 scopus 로고    scopus 로고
    • MRL/Mp CD4+, CD25- T cells show reduced sensitivity to suppression by CD4+, CD25+ regulatory T cells in vitro: A novel defect of T cell regulation in systemic lupus erythematosus
    • Monk CR, Spachidou M, Rovis F, Leung E, Botto M, Lechler RI et al. MRL/Mp CD4+, CD25- T cells show reduced sensitivity to suppression by CD4+, CD25+ regulatory T cells in vitro: A novel defect of T cell regulation in systemic lupus erythematosus. Arthritis Rheum 2005; 52: 1180-1184.
    • (2005) Arthritis Rheum , vol.52 , pp. 1180-1184
    • Monk, C.R.1    Spachidou, M.2    Rovis, F.3    Leung, E.4    Botto, M.5    Lechler, R.I.6
  • 32
    • 0034085594 scopus 로고    scopus 로고
    • Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice
    • Haywood ME, Hogarth MB, Slingsby JH, Rose SJ, Allen PJ, Thompson EM et al. Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice. Arthritis Rheum 2000; 43: 349-355.
    • (2000) Arthritis Rheum , vol.43 , pp. 349-355
    • Haywood, M.E.1    Hogarth, M.B.2    Slingsby, J.H.3    Rose, S.J.4    Allen, P.J.5    Thompson, E.M.6
  • 33
    • 0032520923 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes
    • Mohan C, Alas E, Morel L, Yang P, Wakeland EK. Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes. J Clin Invest 1998; 101: 1362-1372.
    • (1998) J Clin Invest , vol.101 , pp. 1362-1372
    • Mohan, C.1    Alas, E.2    Morel, L.3    Yang, P.4    Wakeland, E.K.5
  • 34
    • 0035808778 scopus 로고    scopus 로고
    • CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: A model to explain spontaneous T cell activation in lupus
    • Vratsanos GS, Jung S, Park YM, Craft J. CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: A model to explain spontaneous T cell activation in lupus. J Exp Med 2001; 193: 329-337.
    • (2001) J Exp Med , vol.193 , pp. 329-337
    • Vratsanos, G.S.1    Jung, S.2    Park, Y.M.3    Craft, J.4
  • 35
    • 33746342994 scopus 로고    scopus 로고
    • Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
    • Sakaguchi S, Ono M, Setoguchi R, Yagi H, Hori S, Fehervari Z et al Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 2006; 212 8-27.
    • (2006) Immunol Rev , vol.212 , pp. 8-27
    • Sakaguchi, S.1    Ono, M.2    Setoguchi, R.3    Yagi, H.4    Hori, S.5    Fehervari, Z.6
  • 36
    • 29144516273 scopus 로고    scopus 로고
    • Global natural regulatory T cell depletion in active systemic lupus erythematosus
    • Miyara M, Amoura Z, Parizot C, Badoual C, Dorgham K, Trad S et al. Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol 2005; 175: 8392-8400.
    • (2005) J Immunol , vol.175 , pp. 8392-8400
    • Miyara, M.1    Amoura, Z.2    Parizot, C.3    Badoual, C.4    Dorgham, K.5    Trad, S.6
  • 37
    • 33645051462 scopus 로고    scopus 로고
    • Inverse correlation between CD4+ regulatory T-cell population and autoantibody levels in paediatric patients with systemic lupus erythematosus
    • Lee JH, Wang LC, Lin YT, Yang YH, Lin DT, Chiang BL. Inverse correlation between CD4+ regulatory T-cell population and autoantibody levels in paediatric patients with systemic lupus erythematosus. Immunology 2006; 117: 280-286.
    • (2006) Immunology , vol.117 , pp. 280-286
    • Lee, J.H.1    Wang, L.C.2    Lin, Y.T.3    Yang, Y.H.4    Lin, D.T.5    Chiang, B.L.6
  • 38
    • 33846900430 scopus 로고    scopus 로고
    • Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus
    • Valencia X, Yarboro C, Illei G, Lipsky PE. Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus. J Immunol 2007; 178: 2579-2588.
    • (2007) J Immunol , vol.178 , pp. 2579-2588
    • Valencia, X.1    Yarboro, C.2    Illei, G.3    Lipsky, P.E.4
  • 39
    • 20444364910 scopus 로고    scopus 로고
    • Genetic determination of T-cell help in loss of tolerance to nuclear antigens
    • Chen Y, Cuda C, Morel L. Genetic determination of T-cell help in loss of tolerance to nuclear antigens. J Immunol 2005; 174: 7692-7702.
    • (2005) J Immunol , vol.174 , pp. 7692-7702
    • Chen, Y.1    Cuda, C.2    Morel, L.3
  • 40
    • 38849101739 scopus 로고    scopus 로고
    • Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms
    • Cuda CM, Wan S, Sobel ES, Croker BP, Morel L. Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms. J Immunol 2007; 179: 7439-7447.
    • (2007) J Immunol , vol.179 , pp. 7439-7447
    • Cuda, C.M.1    Wan, S.2    Sobel, E.S.3    Croker, B.P.4    Morel, L.5
  • 41
    • 1642289263 scopus 로고    scopus 로고
    • Separation of the New Zealand Black genetic contribution to lupus from New Zealand Black determined expansions of marginal zone B and B1a cells
    • Atencio S, Amano H, Izui S, Kotzin BL. Separation of the New Zealand Black genetic contribution to lupus from New Zealand Black determined expansions of marginal zone B and B1a cells. J Immunol 2004; 172: 4159-4166.
    • (2004) J Immunol , vol.172 , pp. 4159-4166
    • Atencio, S.1    Amano, H.2    Izui, S.3    Kotzin, B.L.4
  • 42
    • 0027336832 scopus 로고
    • An MRL/MpJ-1pr/1pr substrain with a limited expansion of 1pr double-negative T cells and a reduced autoimmune syndrome
    • Fossati L, Takahashi S, Merino R, Iwamoto M, Aubry JP, Nose M et al An MRL/MpJ-1pr/1pr substrain with a limited expansion of 1pr double-negative T cells and a reduced autoimmune syndrome. Int Immunol 1993; 5: 525-532.
    • (1993) Int Immunol , vol.5 , pp. 525-532
    • Fossati, L.1    Takahashi, S.2    Merino, R.3    Iwamoto, M.4    Aubry, J.P.5    Nose, M.6


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