Stabilization and conformational isomerization of the cofactor during the catalysis in hydrolytic ALDHs

Chemico-Biological Interactions

Volumn 178, Issue 1-3, 2009, Pages 79-83

  Talfournier, François ^a   Pailot, Arnaud ^a   Stinès Chaumeil, Claire ^a   Branlant, Guy ^a  

^a Biopôle de l Université de Lorraine   (France)

Author keywords

Aldehyde dehydrogenase; Cofactor conformations; Deacylation; Hydride transfer; Thioacylenzyme intermediate

Indexed keywords

ALDEHYDE DEHYDROGENASE; HYDROLASE;

ACYLATION; ARTICLE; CATALYSIS; ENZYME ACTIVITY; ISOMERIZATION; MUTANT; NONHUMAN; PROTEIN CONFORMATION; STEREOSPECIFICITY; STREPTOCOCCUS;

ALDEHYDE DEHYDROGENASE; BIOCATALYSIS; ENZYME STABILITY; HYDROLYSIS; ISOMERISM; MODELS, MOLECULAR; NIACINAMIDE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION;

STREPTOCOCCUS MUTANS;

EID: 59049107175     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.10.045     Document Type: Article

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