Development of a Gas Empowered Drug Delivery system for peptide delivery in the small intestine

Journal of Controlled Release

Volumn 134, Issue 1, 2009, Pages 11-17

  Sadeghi, A M M ^a,b   Avadi, M R ^b   Ejtemaimehr, Sh ^c   Abashzadeh, Sh ^d   Partoazar, A ^c   Dorkoosh, F ^d   Faghihi, M ^c   Rafiee Tehrani, M ^d   Junginger, H E ^a,e  

^a LEIDEN UNIVERSITY   (Netherlands)

^b Hakim Pharmaceutical Company   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e NARESUAN UNIVERSITY   (Thailand)

Author keywords

Gas Empowered Drug Delivery (GEDD); Mucoadhesive polymer; Permeation enhancer; Peroral insulin delivery; Relative bioavailability

Indexed keywords

GAS EMPOWERED DRUG DELIVERY (GEDD); MUCOADHESIVE POLYMER; PERMEATION ENHANCER; PERORAL INSULIN DELIVERY; RELATIVE BIOAVAILABILITY;

AMINES; BIOCHEMISTRY; DRUG DELIVERY; GASES; INSULIN; POLYMERS;

HORMONES;

CARBON DIOXIDE; CHITO CLEAR; CHITOSAN; EXCIPIENT; INSULIN; MACROGOL; PENETRATION ENHANCING AGENT; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG TRANSPORT; ENTERIC COATED TABLET; EX VIVO STUDY; GAS EMPOWERED DRUG DELIVERY SYSTEM; IN VITRO STUDY; INSULIN RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMALL INTESTINE ABSORPTION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CARBON DIOXIDE; CHITOSAN; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; INSULIN; INTESTINAL ABSORPTION; INTESTINE, SMALL; MALE; POLYETHYLENE GLYCOLS; RABBITS; SHEEP; STOMACH;

EID: 59049087328     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.10.012     Document Type: Article

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