Suppressive effect of tobacco smoke extracts on oral P-glycoprotein function and its impact in smoke-induced insult to oral epidermal cells

Toxicology Letters

Volumn 185, Issue 2, 2009, Pages 116-123

  Pan, Wen Chi ^a   Chen, Ruei Ming ^b   Shen, Yuh Chiang ^a   Chen, Chien Chih ^a   Ueng, Yune Fang ^a,b,c  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Oral cell insult; P glycoprotein; Tobacco smoke

Indexed keywords

2 PROPANOL; BENZO[A]PYRENE; CYCLOHEXANE; GLYCOPROTEIN P; NAPHTHALENE; NICOTINE; TOBACCO SMOKE; VERAPAMIL;

ARTICLE; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EPIDERMIS CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOUTH MUCOSA; PRIORITY JOURNAL; PROTEIN FUNCTION;

CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMIS; HUMANS; IMMUNOBLOTTING; MOUTH MUCOSA; P-GLYCOPROTEIN; SMOKE; TIME FACTORS; TOBACCO;

NICOTIANA TABACUM;

EID: 59049086808     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.12.007     Document Type: Article

References (39)

1. Alley M.C., Scudeiro D.A., Monks A., Hursey M.L., Czerwinsk M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., and Boyd M.R. Feasibility of drug screening with panels of human tumor cell lines using microculture tetrazolium assay. Cancer Res. 48 (1988) 589-601
2. Anglicheau D., Pallet N., Rabant M., Marquet P., Cassinat B., Meria P., Beaune P., Legendre C., and Thervet E. Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolimus interaction. Kidney Int. 70 (2006) 1019-1025
3. Blot W.J., McLaughlin J.K., Winn D.M., Austin D.F., Greenberg R.S., Preston-Martin S., Bernstein L., Schoenberg J.B., Stemhagen A., and Fraumeni Jr. J.F. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res. 48 (1988) 3282-3287
4. Chang J.H., Kochansky C.J., and Shou M. The role of P-glycoprotein in the bioactivation of raloxifene. Drug Metab. Dispos. 34 (2006) 2073-2078
5. Chung C.H., Yang Y.H., Wang T.Y., Shieh T.Y., and Warnakulasuriya S. Oral precancerous disorder associated with areca quid chewing, smoking, and alcohol drinking in southern Taiwan. J. Oral Pathol. Med. 34 (2005) 460-466
6. Colombo A., Bonfanti P., Orsi F., and Camatini M. Differential modulation of cytochrome P-450 1A and P-glycoprotein expression by aryl hydrocarbon receptor agonists and thyroid hormone in Xenopus laevis liver and intestine. Aquat. Toxicol. 63 (2003) 173-186
7. Fardel O., Lecureur V., Corlu A., and Guillouzo A. P-glycoprotein induction in rat liver epithelial cells in response to acute 3-methylcholanthrene treatment. Biochem. Pharmacol. 51 (1996) 1427-1436
8. Fenyvesi F., Fenyvesi E., Szente L., Goda K., Bacsó Z., Bácskay I., Váradi J., Kiss T., Molnár E., Janáky T., Szabó Jr. G., and Vecsernyés M. P-glycoprotein inhibition by membrane cholesterol modulation. Eur. J. Pharm. Sci. 34 (2008) 236-242
9. Greene J.F., Zheng J., Grant D.F., and Hammock B.D. Cytotoxicity of 1,2-epoxynaphthalene is correlated with protein binding and in situ glutathione depletion in cytochrome P4501A1 expressing Sf-21 cells. Toxicol. Sci. 53 (2000) 352-360
10. Idriss H.T., Hannun Y.A., Boulpaep E., and Basavappa S. Regulation of volume-activated chloride channels by P-glycoprotein: phosphorylation has the final say!. J. Physiol. 524 (2000) 629-636
11. Jain V., Das S.N., Luthra K., Shukla N.K., and Ralhan R. Differential expression of multidrug resistance gene product, P-glycoprotein, in normal, dysplastic and malignant oral mucosa in India. Int. J. Cancer 74 (1997) 128-133
12. Kartner N., Evernden-Porelle D., Bradley G., and Ling V. Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature (London) 316 (1985) 820-823
13. Kim M.S., Li S.L., Bertolami C.N., Cherrick H.M., and Park N.H. State of p53,Rb and DCC tumor suppressor genes in human oral cancer cell lines. Anticancer Res. 13 (1993) 1405-1414
14. Kim I., Darwin W.D., and Huestis M.A. Simultaneous determination of nicotine, cotinine, norcotinine, and trans-3′-hydroxycotinine in human oral fluid using solid phase extraction and gas chromatography-mass spectrometry. J. Chromatogr. B 814 (2005) 233-240
15. König J., Rost D., Cui Y., and Keppler D. Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology 29 (1999) 1156-1163
16. 4. Nature (London) 227 (1970) 680-685
17. Lee G., and Piquette-Miller M. Cytokines alter the expression and activity of multidrug resistance transporters in human hepatoma cell lines; analysis using RT-PCR and cDNA microarrays. J. Pharm. Sci. 92 (2003) 2152-2163
18. Lin S.C., Lu S.Y., Lee S.Y., Lin C.Y., Chen C.H., and Chang K.W. Areca (betel) nut extract activates mitogen-activated protein kinases and NF-κB in oral keratinocytes. Int. J. Cancer 116 (2005) 526-535
19. Mathieu M.C., Lapierre I., Brault K., and Raymond M. Aromatic hydrocarbon receptor (AhR)·AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells. J. Biol. Chem. 276 (2001) 4819-4827
20. Muzio L., Staibano S., Pannone G., Mignogna M., Serpico R., Rubini C., Fioroni M., Fanali S., and Piattelli A. The human multidrug resistance gene (MDR-1): immunocytochemical detection of its expression in oral SCC. Anticancer Res. 20 (2000) 2891-2898
21. NIOSH, in press. Manual of Analytical Methods. National Institute of Occupational Safety and Health, Washington, DC. Available at http://www.cdc.gov/niosh/nmam.
22. Okamura N., Hirai M., Tanigawara Y., Tanaka K., Yasuhara M., Ueda K., Komano T., and Hori R. Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney. J. Pharmacol. Exp. Ther. 266 (1993) 1614-1619
23. Penny J.I., and Campell C.F. Active transport of benzo(a)pyrene in apical membrane vesicles from normal human intestinal epithelium. Biochim. Biophys. Acta 1226 (1994) 232-236
24. Piquette-Miller M., Pak A., Kim H., Anari R., and Shahzamani A. Decreased expression and activity of P-glycoprotein in rat liver during acute inflammation. Pharm. Res. 15 (1998) 706-711
25. Riganti C., Miraglia E., Viarisio D., Costamagna C., Pescarmona G., Ghigo D., and Bosia A. Nitric oxide reverts the resistance to doxorubicin in human colon cancer cells by inhibiting the drug efflux. Cancer Res. 65 (2005) 516-525
26. Risner C.H. The determination of benzo(a)pyrene in the total particulate matter of cigarette smoke. J. Chromatogr. Sci. 26 (1988) 113-120
27. Romiti N., Tramonti G., and Chieli E. Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line. Toxicol. Appl. Pharmacol. 183 (2002) 83-91
28. Sadeque A.J., Wandel E., He H., Shah S., and Wood A.J.J. Increased drug delivery to the brain by P-glycoprotein inhibition. Clin. Pharmacol. Ther. 68 (2000) 231-237
29. Smith C.J., and Hansch C. The relative toxicity of compounds in main cigarette smoke condensate. Food Chem. Toxicol. 38 (2000) 637-646
30. Sugihara N., Toyama K., Michihara A., Akasaki K., Tsuji H., and Furuno K. Effects of benzo(a)pyrene on P-glycoprotein-mediated transport in Caco-2 cell monolayer. Toxicology 223 (2006) 156-165
31. Towbin H., Staehelin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76 (1979) 4350-4354
32. van der Deen M., de Vries G.E., Visserman H., Zandbergen W., Postma D.S., Timens W., and Timmer-Bosscha H. Cigarette smoke extract affects functional activity of MRP1 in bronchial epithelial cells. J. Biochem. Mol. Toxicol. 21 (2007) 243-251
33. Vellonen K.S., Honkakoski P., and Urtti A. Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity. Eur. J. Pharm. Sci. 23 (2004) 181-188
34. Walle U.K., and Walle T. Transport of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) across the human intestinal Caco-2 cell monolayer: role of efflux pump. Carcinogenesis 20 (1999) 2153-2157
35. Wang J.S., Markowitz J., and Donovan J. P-glycoprotein does not actively transport nicotine and cotinine. Addict. Biol. 10 (2005) 127-129
36. Yan Y.E., Wang H., Wang T., and Zeng H.G. Indole-3-carbinol alters placental cytochrome P450 1A1 and P-glycoprotein levels in rats: AQ potential role in intensifying fetal intrauterine growth-retardation produced by tobacco smoke. Exp. Toxicol. Pathol. 58 (2006) 39-47
37. Yang S.C., Lin S.C., Chiang W.F., Yen C.Y., Lin C.H., and Liu S.Y. Areca nut extract treatment elicits the fibroblastoid morphological changes, actin re-organization and signaling activation in oral keratinocytes. J. Oral Pathol. Med. 32 (2003) 600-605
38. Yang C.S., and Meng C.L. Regulation of PG synthase by EGF and PDGF in human oral breast, stomach, and fibrosarcoma cancer cell lines. J. Dent. Res. 73 (1994) 1407-1415
39. Yeh G.C., Lopaczynska J., Poore L.M., and Phang J.M. A new functional role for P-glycoprotein: efflux pump for benzo(a)pyrene in human breast cancer CMF-7 cells. Cancer Res. 52 (1992) 6692-6695