Characterization of the effects of charged residues in the intracellular loop on ion permeation in α1 glycine receptor channels

Journal of Biological Chemistry

Volumn 284, Issue 4, 2009, Pages 2023-2030

  Carland, Jane E ^a,b   Cooper, Michelle A ^b   Sugiharto, Silas ^a   Jeong, Hyo Jin ^a   Lewis, Trevor M ^a   Barry, Peter H ^a   Peters, John A ^b   Lambert, Jeremy J ^b   Moorhouse, Andrew J ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPHYSICS; DYES; IONS;

CATION SELECTIVITIES; CHANNEL CONDUCTANCES; CHANNEL PORES; CHARGED RESIDUES; FUNCTIONAL PROPERTIES; GLYCINE RECEPTORS; HEK-293 CELLS; INTRACELLULAR DOMAINS; INTRACELLULAR LOOPS; ION PERMEATIONS; MEMBRANE POTENTIALS; NERVOUS SYSTEMS; NON-FUNCTIONAL; PERMEATION PROPERTIES; POSITIVE POTENTIALS; RECEPTOR CHANNELS; SYNAPTIC TRANSMISSIONS; TRANS-MEMBRANE PORES; WILD TYPES;

CELL MEMBRANES;

ALPHA1 GLYCINE RECEPTOR; ANION; CATION; GLUTAMATE AMMONIA LIGASE; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; GLYCINE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE POTENTIAL; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; ION TRANSPORT; MUTATION; NERVOUS SYSTEM; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; ELECTROPHYSIOLOGY; HUMANS; IONS; MOLECULAR SEQUENCE DATA; MUTATION; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; RECEPTORS, GLYCINE; SEQUENCE ALIGNMENT;

EID: 59049083491     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M806618200     Document Type: Article

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