C-terminal residues of mature human T-lymphotropic virus type 1 protease are critical for dimerization and catalytic activity

Biochemical Journal

Volumn 416, Issue 3, 2008, Pages 357-364

  Kádas, János ^a   Boross, Péter ^a   Weber, Irene T ^b   Bagossi, Péter ^a   Matúz, Krisztina ^a   Tözsér, József ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Dimerization; Gel filtration; Human T cell lymphotrophic virus type 1 (HTLV 1); Molecular modelling; Pull down assay; Retroviral protease

Indexed keywords

GEL FILTRATION; HUMAN T-CELL LYMPHOTROPHIC VIRUS TYPE 1 (HTLV-1); MOLECULAR MODELLING; PULL-DOWN ASSAY; RETROVIRAL PROTEASE;

ASSAYS; CHEMOTHERAPY; DIMERIZATION; ENZYMES; GELATION; GELS; HYDROPHOBICITY; MOLECULAR MODELING; POROUS MATERIALS; TUNNELS;

ENZYME INHIBITION;

PROTEINASE; ASPARTIC PROTEINASE; HTLV 1 PROTEASE; HTLV-1 PROTEASE; ISOENZYME; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; DIMERIZATION; ENZYME KINETICS; HUMAN T CELL LEUKEMIA VIRUS 1; HYDROPHOBICITY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; RESIDUE ANALYSIS; SEQUENCE ALIGNMENT; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN QUATERNARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN T-LYMPHOTROPIC VIRUS 1;

AMINO ACID SEQUENCE; ASPARTIC ENDOPEPTIDASES; DIMERIZATION; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, QUATERNARY; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 58949097018     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20071132     Document Type: Article

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