Synthesis and Evaluation of Non-peptidic Cysteine Protease Inhibitors of P. falciparum Derived from Etacrynic Acid

Molecules

Volumn 14, Issue 1, 2009, Pages 19-35

  Dude, Marie Adrienne ^a   Kaeppler, Ulrich ^a   Herb, Monika ^a   Schiller, Markus ^a   Schulz, Franziska ^b   Vedder, Birgit ^a   Heppner, Saskia ^b   Pradel, Gabriele ^a   Gut, Jiri ^c   Rosenthal, Philip J ^c   Schirmeister, Tanja ^a   Leippe, Matthias ^b   Gelhaus, Christoph ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cysteine protease inhibitor; Etacrynic acid; Malaria

Indexed keywords

ANTIMALARIAL AGENT; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; DRUG DERIVATIVE; ETACRYNIC ACID; FALCIPAIN 2; FALCIPAIN 3; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; PLASMODIUM FALCIPARUM; SYNTHESIS;

ANIMALS; ANTIMALARIALS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ETHACRYNIC ACID; MOLECULAR STRUCTURE; PLASMODIUM FALCIPARUM; RECOMBINANT PROTEINS;

EID: 58949091589     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules14010019     Document Type: Article

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