Persistence and fate of highly soluble pharmaceutical products in various types of municipal wastewater treatment plants

WIT Transactions on Ecology and the Environment

Volumn 109, Issue , 2008, Pages 799-807

  Gagnon, C ^a   Lajeunesse, A ^a  

^a ENVIRONMENT CANADA   (Canada)

Author keywords

Fate; Pharmaceuticals; Removal; Treatment plant; Wastewater

Indexed keywords

CONCENTRATION (COMPOSITION); CONFERENCE PROCEEDING; DRUG; EFFLUENT; ENVIRONMENTAL FATE; PHYSICOCHEMICAL PROPERTY; POLLUTANT REMOVAL; POLLUTANT SOURCE; SOLUBILITY; WASTEWATER; WATER TREATMENT;

EID: 58849134238     PISSN: 17433541     EISSN: None     Source Type: Journal    
DOI: 10.2495/WM080811     Document Type: Conference Paper

References (18)

1. Daughton, C.G. & Ternes, T.A. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ. Health Perspect., 107 (suppl. 6), pp. 907-938, 1999.
2. Kolpin, D.W., Furlong, E.T., Meyer, M.T., Thurman, E.M., Zaugg, S.D., Barber, L.B., Buxton, H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. stream, 1999-2000: a national reconnaissance. Environ. Sci. Technol, 36, pp. 1202-1211, 2002.
3. Halling-Sørensen, B., Nors Nielsen, S., Lanzky, P.F., Ingerslev, F., Holten Lutzhoft, H.C., Jorgensen, S.E. Occurrence, fate and effects of pharmaceutical substances in the environment - a review. Chemosphere, 36, pp. 357-393, 1998.
4. nd edition, Springer: Berlin Heidelberg New-York, 2004.
5. Gentili, A. Determination of non-steroidal anti-inflammatory drugs in environmental samples by chromatographic and electrophoretic techniques. Anal. Bioanal. Chem., 387, pp. 1185-1202, 2007.
6. Heberer, T., Dünnbier, U., Reilich, C., Stan, H.J. Detection of drugs and drug metabolites in ground water samples of a drinking water treatment plant. Fresen. Environ. Bull., 6, pp. 438-443, 1997.
7. Ternes, T.A. Occurrence of drugs in German sewage treatment plants and rivers. Water Res., 32, pp. 3245-3260, 1998.
8. O'Brien, E. & Dietrich, D.R. Hindsight rather than foresight: reality versus the EU draft guideline on pharmaceuticals in the environment. Trends Biotechnol., 22 (7), pp. 327-330, 2004.
9. Gehr R. & Nicell J. Pilot studies and assessment of downstream effects of UV and ozone disinfection of a physicochemical wastewater. Wat. Qual. Res. J. Canada, 31, pp. 263-281, 1996.
10. Lajeunesse, A. & Gagnon, C. Determination of acidic pharmaceuticals and carbamazepine in roughly treated sewage by solid phase extraction and gas chromatography-tandem mass spectrometry. Intern. J. Environ. Anal. Chem., 87 (8), pp. 565-578, 2007.
11. Segura, P.A., García-Ac, A., Lajeunesse, A., Ghosh, D., Gagnon, C., Sauvé, S. Determination of six anti-infectives in wastewater using tandem solid-phase extraction and liquid chromatography-tandem mass spectrometry. J. Environ. Monit., 9, pp. 307-313, 2007,
12. Snyder S.A, Westerhoff P. Yoon Y, Sedlak D.L. Pharmaceuticals, personal care products, and endocrine disrupters in water: Implication for the water industry. Environ. Eng. Sci. 20, pp. 449-469, 2003.
13. Lishman L, Smyth SA, Sarafin K, Kleywegt S, Toito J, Peart T, Lee B, Servos M, Beland M, Seto P. Occurrence and reductions of pharmaceuticals and personal care products and estrogens by municipal wastewater treatment plants in Ontario, Canada. Sci. Tot. Environ. 367, pp. 544-558, 2006.
14. Heberer T. Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicol. Lett., 131 (1-2), pp. 5-17, 2002.
15. Hirsch, R, Ternes, T., Haberer, K. Occurrence of antibiotics in the aquatic environment. Sci. Tot. Env., 225, pp, 109-118, 1999.
16. Clara, M., Strenn, B., Kreuzinger, N. Carbamazepine as a possible anthropogenic marker in the aquatic environment: investigations on the behaviour of carbamazepine in wastewater treatment and during groundwater infiltration. Water Res., 38, pp. 947-954, 2004.
17. Lee, H.B., Sarafin, K., Peart, T.E., Svoboda, M.L. Acidic pharmaceuticals in sewage - Methodology, stability test, occurrence, and removal from Ontario samples. Water Qual. Res. J. Canada, 38, pp. 667-682, 2003.
18. Miao, X.S., Koenig, B.G., Metcalfe, C.D. Analysis of acidic drugs in the effluents of sewage treatment plants using liquid chromatography-electrospray ionization tandem mass spectrometry. J. Chromatogr. A., 952, pp. 139-147, 2002.