Uncultivated bacteria as etiologic agents of intra-amniotic inflammation leading to preterm birth

Journal of Clinical Microbiology

Volumn 47, Issue 1, 2009, Pages 38-47

  Han, Yiping W ^a,b   Shen, Tao ^a   Chung, Peter ^a   Buhimschi, Irina A ^c   Buhimschi, Catalin S ^c  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; INTERLEUKIN 6; RNA 16S;

ADULT; AMNION FLUID; AMNIONITIS; ARTICLE; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; BACTEROIDES; BERGEYELLA; CHORIOAMNIONITIS; CLINICAL ARTICLE; CLOSTRIDIALES; CONTROLLED STUDY; FEMALE; FUSOBACTERIUM NUCLEATUM; GENE AMPLIFICATION; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN TISSUE; LEPTOTRICHIA; MOLECULAR CLONING; NEWBORN SEPSIS; NUCLEOTIDE SEQUENCE; PEPTOSTREPTOCOCCUS; PHYLOGENETIC TREE; POLYMERASE CHAIN REACTION; PREMATURE LABOR; PRIORITY JOURNAL; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY;

ADULT; AMNION; AMNIOTIC FLUID; BACTERIA; BACTERIAL INFECTIONS; CLONING, MOLECULAR; DNA, BACTERIAL; DNA, RIBOSOMAL; FEMALE; HUMANS; INFANT, NEWBORN; MASS SPECTROMETRY; POLYMERASE CHAIN REACTION; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREMATURE BIRTH; PROTEOME; RNA, RIBOSOMAL, 16S;

BACTERIA (MICROORGANISMS); BACTEROIDES SP.; BERGEYELLA; CLOSTRIDIALES; FUSOBACTERIUM NUCLEATUM; LEPTOTRICHIA; SNEATHIA;

EID: 58849127455     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.01206-08     Document Type: Article

References (54)

1. ACOG Committee on Practice Bulletins-Obstetrics. 2007. ACOG Practice Bulletin No. 80: premature rupture of membranes. Clinical management guidelines for obstetrician-gynecologists. Obstet. Gynecol. 109:1007- 1019.
2. Barron, E. J., J. H. Jorgensen, M. L. Landry, and M. A. Pfaller. 2007. Bacteriology, p. 974. In P. R. Murray, E. J. Baron, J. H. Jorgensen, M. L. Landry, and M. A. Pfaller (ed.), Manual of clinical microbiology, 9th ed. ASM Press, Washington, DC.
3. Bearfield, C., E. S. Davenport, V. Sivapathasundaram, and R. P. Allaker. 2002. Possible association between amniotic fluid micro-organism infection and microflora in the mouth. Br. J. Obstet. Gynaecol. 109:527-533.
4. Bosshard, P. P., R. Zbinden, S. Abels, B. Boddinghaus, M. Altwegg, and E. C. Böttger. 2006.16S rRNA gene sequencing versus the API 20 NE system and the VITEK 2 ID-GNB card for identification of nonfermenting gram-negative bacteria in the clinical laboratory. J. Clin. Microbiol. 44:1359-1366.
5. Bowen, J. M., L. Chamley, J. A. Keelan, and M. D. Mitchell. 2002. Cytokines of the placenta and extra-placental membranes: roles and regulation during human pregnancy and parturition. Placenta 23:257-273.
6. Buhimschi, C. S., V. Bhandari, B. D. Hamar, M. O. Bahtiyar, G. Zhao, A. K. Sfakianaki, C. M. Pettker, L. Magloire, E. Funai, E. R. Norwitz, M. Paidas, J. A. Copel, C. P. Weiner, C. J. Lockwood, and I. A. Buhimschi. 2007. Proteomic profiling of the amniotic fluid to detect inflammation, infection, and neonatal sepsis. PLoS Med. 4:e18.
7. Buhimschi, C. S., I. A. Buhimschi, S. Abdel-Razeq, V. A. Rosenberg, S. F. Thung, G. Zhao, E. Wang, and V. Bhandari. 2007. Proteomic biomarkers of intra-amniotic inflammation: relationship with funisitis and early-onset sepsis in the premature neonate. Pediatr. Res. 61:318-324.
8. Buhimschi, C. S., V. A. Rosenberg, A. T. Dulay, S. Thung, A. K. Sfakianaki, M. O. Bahtiyar, and I. A. Buhimschi. 2008. Multidimensional system biology: genetic markers and proteomic biomarkers of adverse pregnancy outcome in preterm birth. Am. J. Perinatol. 25:175-187.
9. Buhimschi, I. A., R. Christner, and C. S. Buhimschi. 2005. Proteomic bio-marker analysis of amniotic fluid for identification of intra-amniotic inflammation. Br. J. Obstet. Gynaecol. 112:173-181.
10. Buhimschi, I. A., E. Zambrano, C. M. Pettker, M. O. Bahtiyar, M. Paidas, V. A. Rosenberg, S. Thung, C. M. Salafia, and C. S. Buhimschi. 2008. Using proteomic analysis of the human amniotic fluid to identify histologic chorio-amnionitis. Obstet. Gynecol. 111:403-412.
11. Buhimschi, I. A., G. Zhao, V. A. Rosenberg, S. Abdel-Razeq, S. Thung, and C. S. Buhimschi. 2008. Multidimensional proteomics analysis of amniotic fluid to provide insight into the mechanisms of idiopathic preterm birth. PLoS One 3:e2049.
12. Cassell, G. H., K. B. Waites, H. L. Watson, D. T. Crouse, and R. Harasawa. 1993. Ureaplasma urealyticum intrauterine infection: role in prematurity and disease in newborns. Clin. Microbiol. Rev. 16:69-87.
13. Cho, J. C., and J. M. Tiedje. 2001. Bacterial species determination from DNA-DNA hybridization by using genome fragments and DNA microarrays. Appl. Environ. Microbiol. 67:3677-3682.
14. De Martino, S. J., I. Mahoudeau, J. P. Brettes, Y. Piemont, H. Monteil, and B. Jaulhac. 2004. Peripartum bacteremias due to Leptotrichia amnionii and Sneathia sanguinegens, rare causes of fever during and after delivery. J. Clin. Microbiol. 42:5940-5943.
15. Dong, J., J. P. Olano, J. W. McBride, and D. H. Walker. 2008. Emerging pathogens: challenges and successes of molecular diagnostics. J. Mol. Diagn. 10:185-197.
16. Elovitz, M. A. 2006. Anti-inflammatory interventions in pregnancy: now and the future. Semin. Fetal Neonatal Med. 11:327-332.
17. Gardella, C., D. E. Riley, J. Hitti, K. Agnew, J. N. Krieger, and D. Eschen- bach. 2004. Identification and sequencing of bacterial rDNAs in culture-negative amniotic fluid from women in premature labor. Am. J. Perinatol. 21:319-323.
18. Goldenberg, R. L., J. C. Hauth, and W. W. Andrews. 2000. Intrauterine infection and preterm delivery. N. Engl. J. Med. 342:1500-1507.
19. Han, Y. W., A. Ikegami, N. F. Bissada, M. Herbst, R. W. Redline, and G. G. Ashmead. 2006. Transmission of an uncultivated Bergeyella strain from the oral cavity to amniotic fluid in a case of preterm birth. J. Clin. Microbiol. 44:1475-1483.
20. Han, Y. W., R. W. Redline, M. Li, L. Yin, G. B. Hill, and T. S. McCormick. 2004. Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth. Infect. Immun. 72:2272-2279.
21. Hanff, P. A., J. A. Rosol-Donoghue, C. A. Spiegel, K. H. Wilson, and L. H. Moore. 1995. Leptotrichia sanguinegens sp. nov., a new agent of postpartum and neonatal bacteremia. Clin. Infect. Dis. 20:S237-S239.
22. Hill, G. B. 1993. Investigating the source of amniotic fluid isolates of fuso- bacteria. Clin. Infect. Dis. 16:S423-S424.
23. Hill, G. B. 1998. Preterm birth: associations with genital and possibly oral microflora. Ann. Periodontol. 3:222-332.
24. Hitti, J., D. E. Riley, M. A. Krohn, S. L. Hillier, K. J. Agnew, J. N. Krieger, and D. A. Eschenbach. 1997. Broad-spectrum bacterial rDNA polymerase chain reaction assay for detecting amniotic fluid infection among women in premature labor. Clin. Infect. Dis. 24:1228-1232.
25. Huskins, W. C., J. K. Griffiths, A. S. Faruque, and M. L. Bennish. 1994. Shigellosis in neonates and young infants. J. Pediatr. 125:14-22.
26. Jalava, J., M. L. Mantymaa, U. Ekblad, P. Toivanen, M. Skurnik, O. Lassila, and A. Alanen. 1996. Bacterial 16S rDNA polymerase chain reaction in the detection of intraamniotic infection. Br. J. Obstet. Gynaecol. 103:664-669.
27. Kong, F., and G. L. Gilbert. 2004. Postgenomic taxonomy of human urea-plasmas-a case study based on multiple gene sequences. Int. J. Syst. Evol. Microbiol. 54:1815-1821.
28. Kong, F., G. James, Z. Ma, S. Gordon, B. Wang, and G. L. Gilbert. 1999. Phylogenetic analysis of Ureaplasma urealyticum-support for the establishment of a new species, Ureaplasma parvum. Int. J. Syst. Bacteriol. 49:1879-1889.
29. Kong, F., Z. Ma, G. James, S. Gordon, and G. L. Gilbert. 2000. Species identification and subtyping of Ureaplasma parvum and Ureaplasma urealyticum using PCR-based assays. J. Clin. Microbiol. 38:1175-1179.
30. Kumar, P. S., A. L. Griffen, J. A. Barton, B. J. Paster, M. L. Moeschberger, and E. J. Leys. 2003. New bacterial species associated with chronic periodontitis. J. Dent. Res. 82:338-344.
31. Kuypers, M. M. 2007. Microbiology. Sizing up the uncultivated majority. Science 317:1510-1511.
32. Lechene, C. P., Y. Luyten, G. McMahon, and D. L. Distel. 2007. Quantitative imaging of nitrogen fixation by individual bacteria within animal cells. Science 317:1563-1566.
33. Liu, H., R. Redline, and Y. W. Han. 2007. Fusobacterium nucleatum induces fetal death in mice by stimulating TLR4-mediated inflammatory response. J. Immunol. 179:2501-2508.
34. Madianos, P. N., S. Lieff, A. P. Murtha, K. A., Boggess, R. L. Auten Jr., J. D. Beck, and S. Offenbacher. 2001. Maternal periodontitis and prematurity. Part II. Maternal infection and fetal exposure. Ann. Periodontol. 6:175-182.
35. Martínez, M. A., A. Ovalle, A. Santa-Cruz, B. Barrera, R. Vidal, and R. Aguirre. 2001. Occurrence and antimicrobial susceptibility of Ureaplasma parvum (Ureaplasma urealyticum biovar 1) and Ureaplasma urealyticum (Ureaplasma urealyticum biovar 2) from patients with adverse pregnancy outcomes and normal pregnant women. Scand. J. Infect. Dis. 33:604-610.
36. Naef, R. W., J. R. Allbert III, E. L. Ross, B. M. Weber, R. W. Martin, and J. C. Morrison. 1998. Premature rupture of membranes at 34 to 37 weeks' gestation: aggressive versus conservative management. Am. J. Obstet. Gynecol. 178:126-130.
37. Naeye, R. L. 1992. Disorders of the placenta and decidua, p. 118-247. In R. L. Naeye (ed.), Disorders of the placenta, fetus and neonate: diagnosis and clinical significance. Mosby, St. Louis, MO.
38. Pettker, C. M., I. A. Buhimschi, L. K. Magloire, A. K. Sfakianaki, B. D. Hamar, and C. S. Buhimschi. 2007. Value of placental microbial evaluation in diagnosing intra-amniotic infection. Obstet. Gynecol. 109:739-749.
39. Riesenfeld, C. S., P. D. Schloss, and J. Handelsman. 2004. Metagenomics: genomic analysis of microbial communities. Annu. Rev. Genet. 38:525-552.
40. Rodwell, R. L., A. L. Leslie, and D. I. Tudehope. 1988. Early diagnosis of neonatal sepsis using a hematologic scoring system. J. Pediatr. 112:761-767.
41. Rodwell, R. L., K. M. Taylor, D. I. Tudehope, and P. H. Gray. 1993. Hematologic scoring system in early diagnosis of sepsis in neutropenic newborns. Pediatr. Infect. Dis. J. 12:372-376.
42. Romero, R., B. Sibai, S. Caritis, R. Paul, R. Depp, M. Rosen, M. Klebanoff, V. Sabo, J. Evans, and E. Thom. 1993. Antibiotic treatment ofpretermlabor with intact membranes: a multicenter, randomized, double-blinded, placebo-controlled trial. Am. J. Obstet. Gynecol. 169:764-774.
43. Saigal, S., and L. W. Doyle. 2008. An overview of mortality and sequelae of preterm birth from infancy to adulthood. Lancet 371:261-269.
44. Salafia, C. M., C. A. Vogel, A. M. Vintzileos, K. F. Bantham, J. Pezzullo, and L. Silberman. 1991. Placental pathologic findings in preterm birth. Am. J. Obstet. Gynecol. 165:934-938.
45. Salafia, C. M., C. Weigl, and L. Silberman. 1989. The prevalence and distribution of acute placental inflammation in uncomplicated term pregnancies. Obstet. Gynecol. 73:383-389.
46. Sawardekar, K. P. 2005. Shigellosis caused by Shigella boydii in a preterm neonate, masquerading as necrotizing enterocolitis. Pediatr. Infect. Dis. J. 24:184-185.
47. Shukla,S.K.,P.R.Meier,P.D.Mitchell,D.N.Frank,andK.D.Reed.2002. Leptotrichia amnioniisp. nov., a novel bacterium isolated from the amniotic fluid of a woman after intrauterine fetal demise. J. Clin. Microbiol. 40:3346-3349.
48. Stackebrandt, E., C. Sproer, F. A. Rainey, J. Burghardt, O. Paauker, and H. Hippe. 1997. Phylogenetic analysis of the genus Desulfotomaculum: evidence for the misclassification of Desulfotomaculum guttoideum and description of Desulfotomaculum orientis as Desulfosporosinus orientis gen. nov., comb. nov. Int. J. Syst. Bacteriol. 47:1134-1139.
49. Steer, P. J. 2006. The epidemiology of preterm labour-why have advances not equated to reduced incidence? Br. J. Obstet. Gynaecol. 113(Suppl. 3): 1-3.
50. Tamura, K., J. Dudley, M. Nei, and S. Kumar. 2007. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol. Biol. Evol. 24:1596-1599.
51. Thompson, J. D., T. J. Gibson, F. Plewniak, F. Jeanmougin, and D. G. Higgins. 1997. The ClustalX Windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 24:4876-4882.
52. Watts, D. H., M. A. Krohn, S. L. Hillier, and D. A. Eschenbach. 1992. The association of occult amniotic fluid infection with gestational age and neonatal outcome among womenin preterm labor. Obstet. Gynecol. 79:351-357.
53. Weng, L., E. M. Rubin, and J. Bristow. 2006. Application of sequence-based methods in human microbial ecology. Genome Res. 16:316-322.
54. Yuen, K. Y., P. K. Chan, M. Peiris, D. N. Tsang, T. L. Que, K. F. Shortridge, P. T. Cheung, W. K. To, E. T. Ho, R. Sung, and A. F. Cheng. 1998. Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus. Lancet 351:467-471.