15N{31P} Redor NMR studies of the binding of phosphonate reaction intermediate analogues to saccharomyces cerevisiae lumazine synthase

Biochemistry

Volumn 47, Issue 52, 2008, Pages 13942-13951

  Yu, Tsyr Yan ^a   O'Connor, Robert D ^a   Sivertsen, Astrid C ^a   Chiauzzi, Colby ^b   Poliks, Barbara ^b   Fischer, Markus ^c   Bacher, Adelbert ^d   Haase, Ilka ^c   Cushman, Mark ^e   Schaefer, Jacob ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b BINGHAMTON UNIVERSITY   (United States)

^c UNIVERSITY OF HAMBURG   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHETIC PRECURSORS; INORGANIC PHOSPHATES; LUMAZINE SYNTHASE; MOLECULAR DYNAMICS SIMULATIONS; NMR SPECTRUM; NMR STUDIES; ORGANIC PHOSPHATES; OVERALL REACTIONS; PHOSPHONATES; PHOSPHORUS ATOM; REACTION INTERMEDIATE; SACCHAROMYCES CEREVISIAE; SIDE CHAINS; X RAY CRYSTALS;

ATOMIC SPECTROSCOPY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORUS; REACTION KINETICS; YEAST;

REACTION INTERMEDIATES;

ARGININE; HISTIDINE; LUMAZINE SYNTHASE; LYSINE; NITROGEN DERIVATIVE; ORGANOPHOSPHATE; PHOSPHATE; PHOSPHONIC ACID DERIVATIVE; PHOSPHORUS; PYRIMIDINE DERIVATIVE; RIBOFLAVIN; SYNTHETASE; UNCLASSIFIED DRUG; 6,7 DIMETHYL 8 RIBITYLLUMAZINE SYNTHASE; 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE; MULTIENZYME COMPLEX; NITROGEN;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CHEMICAL REACTION; MOLECULAR DYNAMICS; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRECURSOR; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SIMULATION; X RAY CRYSTALLOGRAPHY; CHEMICAL MODEL; ENZYMOLOGY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN CONFORMATION;

SACCHAROMYCES CEREVISIAE;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MULTIENZYME COMPLEXES; NITROGEN ISOTOPES; PHOSPHONIC ACIDS; PHOSPHORUS ISOTOPES; PROTEIN BINDING; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE;

EID: 58849084646     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi8015789     Document Type: Article

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