-
1
-
-
2542486456
-
Asthma: Mechanisms of disease persistence and progression
-
DOI 10.1146/annurev.immunol.22.012703.104716
-
Cohn, L., J. A. Elias, and G. L. Chupp. 2004. Asthma: mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22: 789-815. (Pubitemid 38680442)
-
(2004)
Annual Review of Immunology
, vol.22
, pp. 789-815
-
-
Cohn, L.1
Elias, J.A.2
Chupp, G.L.3
-
2
-
-
0029335074
-
Interleukin-4 is required for the induction of lung Th2 mucosal immunity
-
Coyle, A. J., G. Le Gros, C. Bertrand, S. Tsuyuki, C. H. Heusser, M. Kopf, and G. P. Anderson. 1995. Interleukin-4 is required for the induction of lung Th2 mucosal immunity. Am. J. Respir. Cell Mol. Biol. 13: 54-59.
-
(1995)
Am. J. Respir. Cell Mol. Biol.
, vol.13
, pp. 54-59
-
-
Coyle, A.J.1
Le Gros, G.2
Bertrand, C.3
Tsuyuki, S.4
Heusser, C.H.5
Kopf, M.6
Anderson, G.P.7
-
4
-
-
0029795713
-
Cellular and molecular mechanisms involved in the regulation of eosinophil trafficking in vivo
-
DOI 10.1002/(SICI)1098-1128(199609)16:5<407::AID-MED2>3.0.CO;2-Z
-
Hogan, S. P., and P. S. Foster. 1996. Cellular and molecular mechanisms involved in the regulation of eosinophil trafficking in vivo. Med. Res. Rev. 16: 407-432. (Pubitemid 26276465)
-
(1996)
Medicinal Research Reviews
, vol.16
, Issue.5
, pp. 407-432
-
-
Hogan, S.P.1
Foster, P.S.2
-
5
-
-
0033562979
-
Th2-induced airway mucus production is dependent on IL-4Rα, but not on eosinophils
-
Cohn, L., R. J. Homer, H. MacLeod, M. Mohrs, F. Brombacher, and K. Bottomly. 1999. Th2-induced airway mucus production is dependent on IL-4Rα, but not on eosinophils. J. Immunol. 162: 6178-6183. (Pubitemid 29314980)
-
(1999)
Journal of Immunology
, vol.162
, Issue.10
, pp. 6178-6183
-
-
Cohn, L.1
Homer, R.J.2
MacLeod, H.3
Mohrs, M.4
Brombacher, F.5
Bottomly, K.6
-
6
-
-
0033696860
-
IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development
-
Townsend, J. M., G. P. Fallon, J. D. Matthews, P. Smith, E. H. Jolin, and N. A. McKenzie. 2000. IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development. Immunity 13: 573-583.
-
(2000)
Immunity
, vol.13
, pp. 573-583
-
-
Townsend, J.M.1
Fallon, G.P.2
Matthews, J.D.3
Smith, P.4
Jolin, E.H.5
McKenzie, N.A.6
-
7
-
-
0036141448
-
Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology
-
Temann, U. A., P. Ray, and R. A. Flavell. 2002. Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology. J. Clin. Invest. 109: 29-39.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 29-39
-
-
Temann, U.A.1
Ray, P.2
Flavell, R.A.3
-
8
-
-
33744982858
-
Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells
-
Wang, Y. H., T. Ito, Y. H. Wang, B. Homey, N. Watanabe, R. Martin, C. J. Barnes, B. W. McIntyre, M. Gilliet, R. Kumar, et al. 2006. Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells. Immunity 24: 827-838.
-
(2006)
Immunity
, vol.24
, pp. 827-838
-
-
Wang, Y.H.1
Ito, T.2
Wang, Y.H.3
Homey, B.4
Watanabe, N.5
Martin, R.6
Barnes, C.J.7
McIntyre, B.W.8
Gilliet, M.9
Kumar, R.10
-
9
-
-
33745207614
-
Thymic stromal lymphopoietin in normal and pathogenic T cell development and function
-
DOI 10.1038/ni1360, PII N1360
-
Ziegler, S. F., and Y. J. Liu. 2006. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat. Immunol. 7: 709-714. (Pubitemid 43905869)
-
(2006)
Nature Immunology
, vol.7
, Issue.7
, pp. 709-714
-
-
Ziegler, S.F.1
Liu, Y.-J.2
-
10
-
-
0036301998
-
Human epithelial cells trigger dendritic cell-mediated allergic inflammation by producing TSLP
-
DOI 10.1038/ni805
-
Soumelis, V., P. A. Reche, H. Kanzler, W. Yuan, G. Edward, B. Homey, M. Gilliet, S. Ho, S. Antonenko, A. Lauerma, et al. 2002. Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat. Immunol. 3: 673-680. (Pubitemid 34752477)
-
(2002)
Nature Immunology
, vol.3
, Issue.7
, pp. 673-680
-
-
Soumelis, V.1
Reche, P.A.2
Kanzler, H.3
Yuan, W.4
Edward, G.5
Homey, B.6
Gilliet, M.7
Ho, S.8
Antonenko, S.9
Lauerma, A.10
Smith, K.11
Gorman, D.12
Zurawski, S.13
Abrams, J.14
Menon, S.15
McClanahan, T.16
De Waal-Malefyt, R.17
Bazan, F.18
Kastelein, R.A.19
Liu, Y.-J.20
more..
-
11
-
-
27744510433
-
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
-
DOI 10.1084/jem.20051135
-
Ito, T., Y. H. Wang, O. Duramad, T. Hori, G. J. Delespesse, N. Watanabe, F. X. Qin, Z. Yao, W. Cao, and Y. J. Liu. 2005. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J. Exp. Med. 202: 1213-1223. (Pubitemid 41586952)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.9
, pp. 1213-1223
-
-
Ito, T.1
Wang, Y.-H.2
Duramad, O.3
Hori, T.4
Delespesse, G.J.5
Watanabe, N.6
Qin, F.X.-F.7
Yao, Z.8
Cao, W.9
Liu, Y.-J.10
-
12
-
-
20444365526
-
Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity
-
Ying, S., B. O'Connor, J. Ratoff, Q. Meng, K. Mallett, D. Cousins, D. Robinson, G. Zhang, J. Zhao, T. H. Lee, and C. Corrigan. 2005. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J. Immunol. 174: 8183-8190. (Pubitemid 40806330)
-
(2005)
Journal of Immunology
, vol.174
, Issue.12
, pp. 8183-8190
-
-
Ying, S.1
O'Connor, B.2
Ratoff, J.3
Meng, Q.4
Mallett, K.5
Cousins, D.6
Robinson, D.7
Zhang, G.8
Zhao, J.9
Lee, T.H.10
Corrigan, C.11
-
13
-
-
25844515028
-
Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
-
DOI 10.1038/ni1247, PII N1247
-
Zhou, B., M. R. Comeau, T. De Smedt, H. D. Liggitt, M. E. Dahl, D. B. Lewis, D. Gyramati, T. Aye, D. J. Campbell, and S. F. Ziegler. 2005. Thymic stromal lymphopoietin (TSLP) as a key initiator of allergic airway inflammation in mice. Nat. Immunol. 6: 1047-1053. (Pubitemid 41486190)
-
(2005)
Nature Immunology
, vol.6
, Issue.10
, pp. 1047-1053
-
-
Zhou, B.1
Comeau, M.R.2
De Smedt, T.3
Liggitt, H.D.4
Dahl, M.E.5
Lewis, D.B.6
Gyarmati, D.7
Aye, T.8
Campbell, D.J.9
Ziegler, S.F.10
-
14
-
-
25144525707
-
A role for TSLP in the development of inflammation in an asthma model
-
DOI 10.1084/jem.20050199
-
Al Shami, A., R. Spolski, J. Kelly, A. Keane-Myers, and W. J. Leonard. 2005. A role for TSLP in the development of inflammation in an asthma model. J. Exp. Med. 202: 829-839. (Pubitemid 41345971)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.6
, pp. 829-839
-
-
Al-Shami, A.1
Spolski, R.2
Kelly, J.3
Keane-Myers, A.4
Leonard, W.J.5
-
15
-
-
26844449311
-
Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin
-
DOI 10.1073/pnas.0507385102
-
Li, M., N. Messaddeq, M. Teletin, J. L. Pasquali, D. Metzger, and P. Chambon. 2005. Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin. Proc. Natl. Acad. Sci. USA 102: 14795-14800. (Pubitemid 41457135)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.41
, pp. 14795-14800
-
-
Li, M.1
Messaddeq, N.2
Teletin, M.3
Pasquali, J.-L.4
Metzger, D.5
Chambon, P.6
-
16
-
-
23944459169
-
Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin
-
DOI 10.1084/jem.20041503
-
Yoo, J., M. Omori, D. Gyarmati, B. Zhou, T. Aye, A. Brewer, M. R. Comeau, D. J. Campbell, and S. F. Ziegler. 2005. Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J. Exp. Med. 202: 541-549. (Pubitemid 41186952)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.4
, pp. 541-549
-
-
Yoo, J.1
Omori, M.2
Gyarmati, D.3
Zhou, B.4
Aye, T.5
Brewer, A.6
Comeau, M.R.7
Campbell, D.J.8
Ziegler, S.F.9
-
17
-
-
0025368649
-
Monoclonal antibodies block murine IL-4 receptor function
-
Beckmann, M. P., K. A. Schooley, B. Gallis, T. Vanden Bos, D. Friend, A. R. Alpert, R. Raunio, K. S. Prickett, P. E. Baker, and L. S. Park. 1990. Monoclonal antibodies block murine IL-4 receptor function. J. Immunol. 144: 4212-4217.
-
(1990)
J. Immunol.
, vol.144
, pp. 4212-4217
-
-
Beckmann, M.P.1
Schooley, K.A.2
Gallis, B.3
Vanden Bos, T.4
Friend, D.5
Alpert, A.R.6
Raunio, R.7
Prickett, K.S.8
Baker, P.E.9
Park, L.S.10
-
18
-
-
0035719975
-
Th2 cytokines and asthma: Interleukin-4: Its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists
-
Steinke, J. W., and L. Borish. 2001. Th2 cytokines and asthma: interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists. Respir. Res. 2: 66-70.
-
(2001)
Respir. Res.
, vol.2
, pp. 66-70
-
-
Steinke, J.W.1
Borish, L.2
-
19
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
-
DOI 10.1016/S1074-7613(00)80439-2
-
Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4: 313-319. (Pubitemid 26132509)
-
(1996)
Immunity
, vol.4
, Issue.3
, pp. 313-319
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
20
-
-
0032482159
-
Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice
-
DOI 10.1084/jem.187.9.1537
-
Akimoto, T., F. Numata, M. Tamura, Y. Takata, N. Higashida, T. Takashi, K. Takeda, and S. Akira. 1998. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice. J. Exp. Med. 187: 1537-1542. (Pubitemid 28215412)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.9
, pp. 1537-1542
-
-
Akimoto, T.1
Numata, F.2
Tamura, M.3
Takata, Y.4
Higashida, N.5
Takashi, T.6
Takeda, K.7
Akira, S.8
-
21
-
-
0032536837
-
Signal transducer and activator of transcription factor 6 (Stat6)- Deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
-
DOI 10.1084/jem.187.6.939
-
Kuperman, D., B. Schofield, M. Wills-Karp, and M. J. Grusby. 1998. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J. Exp. Med. 187: 939-948. (Pubitemid 28141667)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.6
, pp. 939-948
-
-
Kuperman, D.1
Schofield, B.2
Wills-Karp, M.3
Grusby, M.J.4
-
22
-
-
0028345697
-
Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue
-
Nakajima, H., H. Sano, T. Nishimura, S. Yoshida, and I. Iwamoto. 1994. Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue. J. Exp. Med. 179: 1145-1154. (Pubitemid 24091773)
-
(1994)
Journal of Experimental Medicine
, vol.179
, Issue.4
, pp. 1145-1154
-
-
Nakajima, H.1
Sano, H.2
Nishimura, T.3
Yoshida, S.4
Iwamoto, I.5
-
23
-
-
17544403613
-
4-integrins and vascular cell adhesion molecule-1
-
Chin, J. E., C. A. Hatfield, G. E. Winterrowd, J. R. Brashler, S. L. Vonderfecht, S. F. Fidler, R. L. Griffin, K. P. Kolbasa, R. F. Krzesicki, L. M. Sly, et al. 1997. Airway recruitment of leukocytes in mice is dependent on α4-integrins and vascular cell adhesion molecule-1. Am. J. Physiol. 272: L219-L229. (Pubitemid 27137261)
-
(1997)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.272
, Issue.2
-
-
Chin, J.E.1
Hatfield, C.A.2
Winterrowd, G.E.3
Brashler, J.R.4
Vonderfecht, S.L.5
Fidler, S.F.6
Griffin, R.L.7
Kolbasa, K.P.8
Krzesicki, R.F.9
Sly, L.M.10
Staite, N.D.11
Richards, I.M.12
-
24
-
-
0026710184
-
IL-4 plays a dominant role in the differential development of Tho into Th1 and Th2 cells
-
Abehsira-Amar, O., M. Gibert, M. Joliy, J. Theze, and D. L. Jankovic. 1992. IL-4 plays a dominant role in the differential development of Tho into Th1 and Th2 cells. J. Immunol. 148: 3820-3829.
-
(1992)
J. Immunol.
, vol.148
, pp. 3820-3829
-
-
Abehsira-Amar, O.1
Gibert, M.2
Joliy, M.3
Theze, J.4
Jankovic, D.L.5
-
25
-
-
0027452977
-
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
-
DOI 10.1038/362245a0
-
Kopf, M., G. Le Gros, M. Bachmann, M. C. Lamers, H. Bluethmann, and G. Kohler. 1993. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 362: 245-248. (Pubitemid 23093629)
-
(1993)
Nature
, vol.362
, Issue.6417
, pp. 245-248
-
-
Kopf, M.1
Le Gros, G.2
Bachmann, M.3
Lamers, M.C.4
Bluethmann, H.5
Kohler, G.6
-
26
-
-
0029266795
-
Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice
-
Brusselle, G., J. Kips, G. Joos, H. Bluethmann, and R. Pauwels. 1995. Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice. Am. J. Respir. Cell Mol. Biol. 12: 254-259.
-
(1995)
Am. J. Respir. Cell Mol. Biol.
, vol.12
, pp. 254-259
-
-
Brusselle, G.1
Kips, J.2
Joos, G.3
Bluethmann, H.4
Pauwels, R.5
-
27
-
-
36849060458
-
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation
-
DOI 10.1172/JCI33559
-
Seshasayee, D., W. P. Lee, M. Zhou, J. Shu, E. Suto, J. Zhang, L. Diehl, C. D. Austin, Y. G. Meng, M. Tan, et al. 2007. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation. J. Clin. Invest. 117: 3868-3878. (Pubitemid 350224096)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.12
, pp. 3868-3878
-
-
Seshasayee, D.1
Lee, W.P.2
Zhou, M.3
Shu, J.4
Suto, E.5
Zhang, J.6
Diehl, L.7
Austin, C.D.8
Meng, Y.G.9
Tan, M.10
Bullens, S.L.11
Seeber, S.12
Fuentes, M.E.13
Labrijn, A.F.14
Graus, Y.M.F.15
Miller, L.A.16
Schelegle, E.S.17
Hyde, D.M.18
Wu, L.C.19
Hymowitz, S.G.20
Martin, F.21
more..
-
28
-
-
3142659551
-
Interleukin-13 in asthma pathogenesis
-
Wills-Karp, M. 2004. Interleukin-13 in asthma pathogenesis. Curr. Allergy Asthma Rep. 4: 123-131.
-
(2004)
Curr. Allergy Asthma Rep.
, vol.4
, pp. 123-131
-
-
Wills-Karp, M.1
-
29
-
-
0028962572
-
The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
-
Lin, J. X., T. S. Migone, M. Tsang, M. Friedmann, J. A. Weatherbee, L. Zhou, A. Yamauchi, E. T. Bloom, J. Mietz, S. John, et al. 1995. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2: 331-339.
-
(1995)
Immunity
, vol.2
, pp. 331-339
-
-
Lin, J.X.1
Migone, T.S.2
Tsang, M.3
Friedmann, M.4
Weatherbee, J.A.5
Zhou, L.6
Yamauchi, A.7
Bloom, E.T.8
Mietz, J.9
John, S.10
-
30
-
-
0030953977
-
Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins
-
Hogan, S. P., A. Mould, H. Kikutani, A. J. Ramsay, and P. S. Foster. 1997. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J. Clin. Invest. 99: 1329-1339.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1329-1339
-
-
Hogan, S.P.1
Mould, A.2
Kikutani, H.3
Ramsay, A.J.4
Foster, P.S.5
-
31
-
-
33847134006
-
Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells
-
DOI 10.1084/jem.20062211
-
Allakhverdi, Z., M. R. Comeau, H. K. Jessup, B. R. Yoon, A. Brewer, S. Chartier, N. Paquette, S. F. Ziegler, M. Sarfati, and G. Delespesse. 2007. Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells. J. Exp. Med. 204: 253-258. (Pubitemid 46294541)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.2
, pp. 253-258
-
-
Allakhverdi, Z.1
Comeau, M.R.2
Jessup, H.K.3
Yoon, B.-R.P.4
Brewer, A.5
Chartier, S.6
Paquette, N.7
Ziegler, S.F.8
Sarfati, M.9
Delespesse, G.10
-
32
-
-
0031004365
-
Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice
-
Gavett, S. H., D. J. O'Hearn, C. L. Karp, E. A. Patel, B. H. Schofield, F. D. Finkelman, and M. Wills-Karp. 1997. Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice. Am. J. Physiol. 272: L253-L261. (Pubitemid 27137265)
-
(1997)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.272
, Issue.2
-
-
Gavett, S.H.1
O'Hearn, D.J.2
Karp, C.L.3
Patel, E.A.4
Schofield, B.H.5
Finkelman, F.D.6
Wills-Karp, M.7
-
33
-
-
33847607512
-
Anti-inflammatory activity of inhaled IL-4 receptor-α antisense oligonucleotide in mice
-
Karras, J. G., J. R. Crosby, M. Guha, D. Tung, D. A. Miller, W. A. Gaarde, R. S. Geary, B. P. Monia, and S. A. Gregory. 2007. Anti-inflammatory activity of inhaled IL-4 receptor-α antisense oligonucleotide in mice. Am. J. Respir. Cell Mol. Biol. 36: 276-285.
-
(2007)
Am. J. Respir. Cell Mol. Biol.
, vol.36
, pp. 276-285
-
-
Karras, J.G.1
Crosby, J.R.2
Guha, M.3
Tung, D.4
Miller, D.A.5
Gaarde, W.A.6
Geary, R.S.7
Monia, B.P.8
Gregory, S.A.9
|