Impregnation of a biocompatible polymer aided by supercritical CO2: Evaluation of drug stability and drug-matrix interactions

Journal of Supercritical Fluids

Volumn 48, Issue 1, 2009, Pages 56-63

  Lopez Periago A ^a   Argemi A ^b   Andanson, J M ^c   Fernandez V ^d   Garcia Gonzalez C A ^a   Kazarian, S G ^c   Saurina, J ^b   Domingo, C ^a  

^a INSTITUT DE CIÈNCIA DE MATERIALS DE BARCELONA ICMAB CSIC   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d FeyeCon Development and Implementation BV   (Netherlands)

Author keywords

Compressed CO2; Drug stability; Hydrogen bond; Impregnation; PMMA; Sustained release

Indexed keywords

BINDING SITES; BODY FLUIDS; CARBON DIOXIDE; CHEMICAL STABILITY; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DRUG PRODUCTS; ESTERS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROGEN; HYDROGEN BONDS; IMPREGNATION; LIQUID CHROMATOGRAPHY; POLYMERS; SUPERCRITICAL FLUID EXTRACTION; SYSTEM STABILITY; THERMOANALYSIS;

COMPRESSED CO2; DRUG STABILITY; HYDROGEN BOND; PMMA; SUSTAINED RELEASE;

DRUG INTERACTIONS;

EID: 58749084288     PISSN: 08968446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.supflu.2008.09.015     Document Type: Article

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