메뉴 건너뛰기




Volumn 7, Issue , 2008, Pages

LIM only 4 is overexpressed in late stage pancreas cancer

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LMO4; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; LMO4 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; STK11 PROTEIN, HUMAN;

EID: 58749083043     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-7-93     Document Type: Article
Times cited : (20)

References (41)
  • 2
    • 0031944260 scopus 로고    scopus 로고
    • Japan Pancreatic Cancer Registry: Current status
    • 10.1097/00006676-199804000-00006 9548661
    • Yamamoto M Ohashi O Saitoh Y Japan Pancreatic Cancer Registry: Current status Pancreas 1998, 16:238-42. 10.1097/00006676-199804000-00006 9548661
    • (1998) Pancreas , vol.16 , pp. 238-242
    • Yamamoto, M.1    Ohashi, O.2    Saitoh, Y.3
  • 3
    • 12144288807 scopus 로고    scopus 로고
    • Pancreatic Cancer Registry in Japan: 20 years of experience
    • 10.1097/00006676-200404000-00002 15084961
    • Matsuno S Egawa S Fukuyama S Motoi F Sunamura M Isaji S et al. Pancreatic Cancer Registry in Japan: 20 years of experience Pancreas 2004, 28:219-30. 10.1097/00006676-200404000-00002 15084961
    • (2004) Pancreas , vol.28 , pp. 219-230
    • Matsuno, S.1    Egawa, S.2    Fukuyama, S.3    Motoi, F.4    Sunamura, M.5    Isaji, S.6
  • 4
    • 33644832500 scopus 로고    scopus 로고
    • Important clues to the diagnosis of pancreatic cancer
    • 16358942
    • Tanaka M Important clues to the diagnosis of pancreatic cancer Roczniki Akademii Medycznej w Bialymstoku (1995) 2005, 50:69-72. 16358942
    • (2005) Roczniki Akademii Medycznej W Bialymstoku (1995) , vol.50 , pp. 69-72
    • Tanaka, M.1
  • 5
    • 0037328351 scopus 로고    scopus 로고
    • Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas
    • 10.1093/carcin/24.2.193 12584167
    • House MG Guo M Iacobuzio-Donahue C Herman JG Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas Carcinogenesis 2003, 24:193-8. 10.1093/carcin/24.2.193 12584167
    • (2003) Carcinogenesis , vol.24 , pp. 193-198
    • House, M.G.1    Guo, M.2    Iacobuzio-Donahue, C.3    Herman, J.G.4
  • 6
    • 3242744313 scopus 로고    scopus 로고
    • An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
    • 10.1097/01.pas.0000126675.59108.80 15252303
    • Hruban RH Takaori K Klimstra DS Adsay NV Albores-Saavedra J Biankin AV et al. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms Am J Surg Pathol 2004, 28:977-87. 10.1097/01.pas.0000126675.59108.80 15252303
    • (2004) Am J Surg Pathol , vol.28 , pp. 977-987
    • Hruban, R.H.1    Takaori, K.2    Klimstra, D.S.3    Adsay, N.V.4    Albores-Saavedra, J.5    Biankin, A.V.6
  • 7
    • 0028081120 scopus 로고
    • K-ras mutations in pancreatic ductal proliferative lesions
    • 1887480 7992857
    • Klimstra DS Longnecker DS K-ras mutations in pancreatic ductal proliferative lesions The American journal of pathology 1994, 145:1547-50. 1887480 7992857
    • (1994) The American Journal of Pathology , vol.145 , pp. 1547-1550
    • Klimstra, D.S.1    Longnecker, D.S.2
  • 8
    • 0036834308 scopus 로고    scopus 로고
    • Genetic alterations in adenoma-carcinoma sequencing of intraductal papillary-mucinous neoplasm of the pancreas
    • 12370756
    • Nakata B Yashiro M Nishioka N Aya M Yamada S Takenaka C Genetic alterations in adenoma-carcinoma sequencing of intraductal papillary-mucinous neoplasm of the pancreas Int J Oncol 2002, 21:1067-72. 12370756
    • (2002) Int J Oncol , vol.21 , pp. 1067-1072
    • Nakata, B.1    Yashiro, M.2    Nishioka, N.3    Aya, M.4    Yamada, S.5    Takenaka, C.6
  • 9
    • 0036142203 scopus 로고    scopus 로고
    • Intraductal papillary-mucinous neoplasms of the pancreas: An analysis of in situ and invasive carcinomas in 28 patients
    • 10.1002/cncr.10203 11815961
    • Adsay NV Conlon KC Zee SY Brennan MF Klimstra DS Intraductal papillary-mucinous neoplasms of the pancreas: An analysis of in situ and invasive carcinomas in 28 patients Cancer 2002, 94:62-77. 10.1002/ cncr.10203 11815961
    • (2002) Cancer , vol.94 , pp. 62-77
    • Adsay, N.V.1    Conlon, K.C.2    Zee, S.Y.3    Brennan, M.F.4    Klimstra, D.S.5
  • 10
    • 0035020633 scopus 로고    scopus 로고
    • Pancreatic intraepithelial neoplasia: A new nomenclature and classification system for pancreatic duct lesions
    • 10.1097/00000478-200105000-00003 11342768
    • Hruban RH Adsay NV Albores-Saavedra J Compton C Garrett ES Goodman SN et al. Pancreatic intraepithelial neoplasia: A new nomenclature and classification system for pancreatic duct lesions Am J Surg Pathol 2001, 25:579-86. 10.1097/00000478-200105000-00003 11342768
    • (2001) Am J Surg Pathol , vol.25 , pp. 579-586
    • Hruban, R.H.1    Adsay, N.V.2    Albores-Saavedra, J.3    Compton, C.4    Garrett, E.S.5    Goodman, S.N.6
  • 11
    • 0141590367 scopus 로고    scopus 로고
    • Clinicopathological features of pancreatic intraepithelial neoplasias and their relationship to intraductal papillary-mucinous tumors
    • 10.1007/s00534-003-0756-8 14505145
    • Takaori K Kobashi Y Matsusue S Matsui K Yamamoto T Clinicopathological features of pancreatic intraepithelial neoplasias and their relationship to intraductal papillary-mucinous tumors J Hepatobiliary Pancreat Surg 2003, 10:125-36. 10.1007/s00534-003-0756-8 14505145
    • (2003) J Hepatobiliary Pancreat Surg , vol.10 , pp. 125-136
    • Takaori, K.1    Kobashi, Y.2    Matsusue, S.3    Matsui, K.4    Yamamoto, T.5
  • 12
    • 27644510498 scopus 로고    scopus 로고
    • Histopathological diagnosis of pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms: Interobserver agreement
    • 10.1097/01.mpa.0000186245.35716.18 16258368
    • Longnecker DS Adsay NV Fernandez-del Castillo C Hruban RH Kasugai T Klimstra DS et al. Histopathological diagnosis of pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms: interobserver agreement Pancreas 2005, 31:344-9. 10.1097/ 01.mpa.0000186245.35716.18 16258368
    • (2005) Pancreas , vol.31 , pp. 344-349
    • Longnecker, D.S.1    Adsay, N.V.2    Fernandez-del Castillo, C.3    Hruban, R.H.4    Kasugai, T.5    Klimstra, D.S.6
  • 13
    • 0032530133 scopus 로고    scopus 로고
    • Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis
    • 21629 9736723 10.1073/pnas.95.19.11257
    • Kenny DA Jurata LW Saga Y Gill GN Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis Proc Natl Acad Sci USA 1998, 95:11257-62. 21629 9736723 10.1073/pnas.95.19.11257
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11257-11262
    • Kenny, D.A.1    Jurata, L.W.2    Saga, Y.3    Gill, G.N.4
  • 14
    • 0025759278 scopus 로고
    • The rhombotin family of cysteine-rich LIM-domain oncogenes: Distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13
    • 51660 2034676 10.1073/pnas.88.10.4367
    • Boehm T Foroni L Kaneko Y Perutz MF Rabbitts TH The rhombotin family of cysteine-rich LIM-domain oncogenes: Distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13 Proc Natl Acad Sci USA 1991, 88:4367-71. 51660 2034676 10.1073/pnas.88.10.4367
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4367-4371
    • Boehm, T.1    Foroni, L.2    Kaneko, Y.3    Perutz, M.F.4    Rabbitts, T.H.5
  • 15
    • 0025933456 scopus 로고
    • TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11)
    • 1923511
    • Royer-Pokora B Loos U Ludwig WD TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11) Oncogene 1991, 6:1887-93. 1923511
    • (1991) Oncogene , vol.6 , pp. 1887-1893
    • Royer-Pokora, B.1    Loos, U.2    Ludwig, W.D.3
  • 16
    • 33646705880 scopus 로고    scopus 로고
    • LMO4 can interact with Smad proteins and modulate transforming growth factor-beta signaling in epithelial cells
    • 10.1038/sj.onc.1209318 16331278
    • Lu Z Lam KS Wang N Xu X Cortes M Andersen B LMO4 can interact with Smad proteins and modulate transforming growth factor-beta signaling in epithelial cells Oncogene 2006, 25:2920-30. 10.1038/sj.onc.1209318 16331278
    • (2006) Oncogene , vol.25 , pp. 2920-2930
    • Lu, Z.1    Lam, K.S.2    Wang, N.3    Xu, X.4    Cortes, M.5    Andersen, B.6
  • 17
    • 0033553020 scopus 로고    scopus 로고
    • Molecular cloning of LMO41, a new human LIM domain gene
    • 10209267
    • Racevskis J Dill A Sparano JA Ruan H Molecular cloning of LMO41, a new human LIM domain gene Biochim Biophys Acta 1999, 1445:148-53. 10209267
    • (1999) Biochim Biophys Acta , vol.1445 , pp. 148-153
    • Racevskis, J.1    Dill, A.2    Sparano, J.A.3    Ruan, H.4
  • 18
    • 0035807896 scopus 로고    scopus 로고
    • The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer
    • 64702 11734645 10.1073/pnas.251547698
    • Visvader JE Venter D Hahm K Santamaria M Sum EY O'Reilly L The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer Proc Natl Acad Sci USA 2001, 98:14452-7. 64702 11734645 10.1073/pnas.251547698
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 14452-14457
    • Visvader, J.E.1    Venter, D.2    Hahm, K.3    Santamaria, M.4    Sum, E.Y.5    O'Reilly, L.6
  • 19
    • 0037040874 scopus 로고    scopus 로고
    • The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity
    • 10.1074/jbc.M110603200 11751867
    • Sum EY Peng B Yu X Chen J Byrne J Lindeman GJ et al. The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity J Biol Chem 2002, 277:7849-56. 10.1074/ jbc.M110603200 11751867
    • (2002) J Biol Chem , vol.277 , pp. 7849-7856
    • Sum, E.Y.1    Peng, B.2    Yu, X.3    Chen, J.4    Byrne, J.5    Lindeman, G.J.6
  • 20
    • 19644372949 scopus 로고    scopus 로고
    • Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer
    • 1140463 15897450 10.1073/pnas.0502990102
    • Sum EY Segara D Duscio B Bath ML Field AS Sutherland RL et al. Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer Proc Natl Acad Sci USA 2005, 102:7659-64. 1140463 15897450 10.1073/pnas.0502990102
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7659-7664
    • Sum, E.Y.1    Segara, D.2    Duscio, B.3    Bath, M.L.4    Field, A.S.5    Sutherland, R.L.6
  • 21
    • 0037779084 scopus 로고    scopus 로고
    • The LIM-only protein, LMO4, and the LIM domain-binding protein, LDB1, expression in squamous cell carcinomas of the oral cavity
    • 10.1038/sj.bjc.6600952 12771919
    • Mizunuma H Miyazawa J Sanada K Imai K et al. The LIM-only protein, LMO4, and the LIM domain-binding protein, LDB1, expression in squamous cell carcinomas of the oral cavity British journal of cancer 2003, 88:1543-8. 10.1038/sj.bjc.6600952 12771919
    • (2003) British Journal of Cancer , vol.88 , pp. 1543-1548
    • Mizunuma, H.1    Miyazawa, J.2    Sanada, K.3    Imai, K.4
  • 22
    • 34848892451 scopus 로고    scopus 로고
    • The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells
    • 10.1038/sj.onc.1210465 17452977
    • Wang N Lin KK Lu Z Lam KS Newton R Xu X et al. The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells Oncogene 2007, 26:6431-41. 10.1038/sj.onc.1210465 17452977
    • (2007) Oncogene , vol.26 , pp. 6431-6441
    • Wang, N.1    Lin, K.K.2    Lu, Z.3    Lam, K.S.4    Newton, R.5    Xu, X.6
  • 23
  • 25
    • 2342640981 scopus 로고    scopus 로고
    • Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions
    • 10.1158/0008-5472.CAN-03-2464 15126362
    • Ohuchida K Mizumoto K Murakami M Qian LW Sato N Nagai E et al. Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions Cancer research 2004, 64:3215-22. 10.1158/0008-5472.CAN-03-2464 15126362
    • (2004) Cancer Research , vol.64 , pp. 3215-3222
    • Ohuchida, K.1    Mizumoto, K.2    Murakami, M.3    Qian, L.W.4    Sato, N.5    Nagai, E.6
  • 26
    • 33745853820 scopus 로고    scopus 로고
    • Overexpression of c-met in the early stage of pancreatic carcinogenesis; altered expression is not sufficient for progression from chronic pancreatitis to pancreatic cancer
    • 16804974
    • Yu J Ohuchida K Mizumoto K Ishikawa N Ogura Y Yamada D et al. Overexpression of c-met in the early stage of pancreatic carcinogenesis; altered expression is not sufficient for progression from chronic pancreatitis to pancreatic cancer World J Gastroenterol 2006, 12:3878-82. 16804974
    • (2006) World J Gastroenterol , vol.12 , pp. 3878-3882
    • Yu, J.1    Ohuchida, K.2    Mizumoto, K.3    Ishikawa, N.4    Ogura, Y.5    Yamada, D.6
  • 27
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • 10.1016/0003-2697(87)90021-2
    • Chomczynski P Sacchi N Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Analytical biochemistry 1987 162 156 9 10.1016/0003-2697(87)90021-2 2440339
    • (1987) Analytical Biochemistry , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 28
    • 3142704586 scopus 로고    scopus 로고
    • A new molecular biology approach in morphology: Basic method and application of laser microdissection
    • 15221649
    • Tachikawa T Irie T A new molecular biology approach in morphology: Basic method and application of laser microdissection Med Electron Microsc 2004, 37:82-8. 15221649
    • (2004) Med Electron Microsc , vol.37 , pp. 82-88
    • Tachikawa, T.1    Irie, T.2
  • 29
    • 0031847421 scopus 로고    scopus 로고
    • Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinoma
    • 1852927 9665487
    • Liu N Furukawa T Kobari M Tsao MS Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic carcinoma The American journal of pathology 1998, 153:263-9. 1852927 9665487
    • (1998) The American Journal of Pathology , vol.153 , pp. 263-269
    • Liu, N.1    Furukawa, T.2    Kobari, M.3    Tsao, M.S.4
  • 30
    • 0033710369 scopus 로고    scopus 로고
    • Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype
    • 1885733 11073822
    • Ouyang H Mou L Luk C Liu N Karaskova J Squire J et al. Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype The American journal of pathology 2000, 157:1623-31. 1885733 11073822
    • (2000) The American Journal of Pathology , vol.157 , pp. 1623-1631
    • Ouyang, H.1    Mou, L.2    Luk, C.3    Liu, N.4    Karaskova, J.5    Squire, J.6
  • 31
    • 0031974516 scopus 로고    scopus 로고
    • Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
    • 10.1038/ng0198-38 9425897
    • Jenne DE Reimann H Nezu J Friedel W Loff S Jeschke R et al. Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase Nature genetics 1998, 18:38-43. 10.1038/ng0198-38 9425897
    • (1998) Nature Genetics , vol.18 , pp. 38-43
    • Jenne, D.E.1    Reimann, H.2    Nezu, J.3    Friedel, W.4    Loff, S.5    Jeschke, R.6
  • 32
    • 0035184065 scopus 로고    scopus 로고
    • STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas
    • 1850608 11733352
    • Sato N Rosty C Jansen M Fukushima N Ueki T Yeo CJ et al. STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas The American journal of pathology 2001, 159:2017-22. 1850608 11733352
    • (2001) The American Journal of Pathology , vol.159 , pp. 2017-2022
    • Sato, N.1    Rosty, C.2    Jansen, M.3    Fukushima, N.4    Ueki, T.5    Yeo, C.J.6
  • 33
    • 0032984141 scopus 로고    scopus 로고
    • Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
    • 1866632 10362809
    • Su GH Hruban RH Bansal RK Bova GS Tang DJ Shekher MC et al. Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers The American journal of pathology 1999, 154:1835-40. 1866632 10362809
    • (1999) The American Journal of Pathology , vol.154 , pp. 1835-1840
    • Su, G.H.1    Hruban, R.H.2    Bansal, R.K.3    Bova, G.S.4    Tang, D.J.5    Shekher, M.C.6
  • 35
    • 0032696589 scopus 로고    scopus 로고
    • Characterization of the Lmo4 gene encoding a LIM-only protein: Genomic organization and comparative chromosomal mapping
    • 10.1007/s003359901167 10556429
    • Tse E Grutz G Garner AA Ramsey Y Carter NP Copeland N et al. Characterization of the Lmo4 gene encoding a LIM-only protein: Genomic organization and comparative chromosomal mapping Mamm Genome 1999, 10:1089-94. 10.1007/s003359901167 10556429
    • (1999) Mamm Genome , vol.10 , pp. 1089-1094
    • Tse, E.1    Grutz, G.2    Garner, A.A.3    Ramsey, Y.4    Carter, N.P.5    Copeland, N.6
  • 36
    • 0006818524 scopus 로고    scopus 로고
    • Correlation of Allelic Losses and Clinicopathological Factors in Primary Breast Cancers
    • 10.1007/BF02966514 11091607
    • Emi M Matsumoto S Iida A Tsukamoto K Nakata T Yokota T et al. Correlation of Allelic Losses and Clinicopathological Factors in Primary Breast Cancers Breast Cancer 1997, 4:243-6. 10.1007/BF02966514 11091607
    • (1997) Breast Cancer , vol.4 , pp. 243-246
    • Emi, M.1    Matsumoto, S.2    Iida, A.3    Tsukamoto, K.4    Nakata, T.5    Yokota, T.6
  • 37
    • 0028819584 scopus 로고
    • Allelic imbalance on chromosome 1 in human breast cancer. II. Microsatellite repeat analysis
    • 10.1002/gcc.2870120105 7534107
    • Hoggard N Brintnell B Howell A Weissenbach J Varley J Allelic imbalance on chromosome 1 in human breast cancer. II. Microsatellite repeat analysis Genes, chromosomes & cancer 1995, 12:24-31. 10.1002/ gcc.2870120105 7534107
    • (1995) Genes, Chromosomes & Cancer , vol.12 , pp. 24-31
    • Hoggard, N.1    Brintnell, B.2    Howell, A.3    Weissenbach, J.4    Varley, J.5
  • 38
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • 395230 8045262
    • Singh P Wong SH Hong W Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation The EMBO journal 1994, 13;3329-38. 395230 8045262
    • (1994) The EMBO Journal , vol.13 , pp. 3329-3338
    • Singh, P.1    Wong, S.H.2    Hong, W.3
  • 39
  • 41
    • 53449089118 scopus 로고    scopus 로고
    • Long-term survival and prognostic indicators in small (< or = 2 cm) pancreatic cancer
    • 10.1159/000161009 18849640
    • Pongprasobchai S Pannala R Smyrk TC Bamlet W Pitchumoni S Ougolkov A et al. Long-term survival and prognostic indicators in small (< or = 2 cm) pancreatic cancer Pancreatology 2008, 8:587-92. 10.1159/000161009 18849640
    • (2008) Pancreatology , vol.8 , pp. 587-592
    • Pongprasobchai, S.1    Pannala, R.2    Smyrk, T.C.3    Bamlet, W.4    Pitchumoni, S.5    Ougolkov, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.