Excessive alcohol consumption is blocked by glial cell line-derived neurotrophic factor

Alcohol

Volumn 43, Issue 1, 2009, Pages 35-43

  Carnicella, Sebastien ^a   Amamoto, Ryoji ^a   Ron, Dorit ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Addiction; Alcohol; Ethanol; GDNF; Growth factor; VTA

Indexed keywords

ALCOHOL; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR;

ALCOHOL CONSUMPTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLIA CELL; HISTOPATHOLOGY; LONG EVANS RAT; MALE; MICROINJECTION; NONHUMAN; RAT; VENTRAL TEGMENTUM;

ALCOHOLISM; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CONDITIONING, OPERANT; DRINKING; ETHANOL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; MALE; MICROINJECTIONS; RATS; RATS, LONG-EVANS; REINFORCEMENT SCHEDULE; VENTRAL TEGMENTAL AREA;

RATTUS;

EID: 58549105969     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.alcohol.2008.12.001     Document Type: Article

References (63)

1. Ai Y., Markesbery W., Zhang Z., Grondin R., Elseberry D., Gerhardt G.A., et al. Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects. J. Comp. Neurol. 461 (2003) 250-261
2. Airaksinen M.S., and Saarma M. The GDNF family: signalling, biological functions and therapeutic value. Nat. Rev. Neurosci. 3 (2002) 383-394
3. Airavaara M., Tuomainen H., Piepponen T.P., Saarma M., and Ahtee L. Effects of repeated morphine on locomotion, place preference and dopamine in heterozygous glial cell line-derived neurotrophic factor knockout mice. Genes Brain Behav. 6 (2007) 287-298
4. Barroso-Chinea P., Cruz-Muros I., Aymerich M.S., Rodriguez-Diaz M., Afonso-Oramas D., Lanciego J.L., et al. Striatal expression of GDNF and differential vulnerability of midbrain dopaminergic cells. Eur. J. Neurosci. 21 (2005) 1815-1827
5. Beck K.D., Valverde J., Alexi T., Poulsen K., Moffat B., Vandlen R.A., et al. Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature 373 (1995) 339-341
6. Bloomfield K., Stockwell T., Gmel G., and Rehn N. International comparisons of alcohol consumption. Alcohol Res. Health 27 (2003) 95-109
7. Brodie M.S., Pesold C., and Appel S.B. Ethanol directly excites dopaminergic ventral tegmental area reward neurons. Alcohol Clin. Exp. Res. 23 (1999) 1848-1852
8. Burazin T.C., and Gundlach A.L. Localization of GDNF/neurturin receptor (c-ret, GFRalpha-1 and alpha-2) mRNAs in postnatal rat brain: differential regional and temporal expression in hippocampus, cortex and cerebellum. Brain Res. Mol. Brain Res. 73 (1999) 151-171
9. Carnicella S., Kharazia V., Jeanblanc J., Janak P.H., and Ron D. GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 8114-8119
10. Darden J.H., and Hunt W.A. Reduction of striatal dopamine release during an ethanol withdrawal syndrome. J. Neurochem. 29 (1977) 1143-1145
11. Dawson D.A., Goldstein R.B., and Grant B.F. Rates and correlates of relapse among individuals in remission from DSM-IV alcohol dependence: a 3-year follow-up. Alcohol Clin. Exp. Res. 31 (2007) 2036-2045
12. Diana M., Brodie M., Muntoni A., Puddu M.C., Pillolla G., Steffensen S., et al. Enduring effects of chronic ethanol in the CNS: basis for alcoholism. Alcohol Clin. Exp. Res. 27 (2003) 354-361
13. Fadda F., and Rossetti Z.L. Chronic ethanol consumption: from neuroadaptations to neurodegeneration. Prog. Neurobiology 56 (1998) 385-431
14. Funk C.K., Zorrilla E.P., Lee M.J., Rice K.C., and Koob G.F. Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats. Biol. Psychiatry 61 (2007) 78-86
15. Glazner G.W., Mu X., and Springer J.E. Localization of glial cell line-derived neurotrophic factor receptor alpha and c-ret mRNA in rat central nervous system. J. Comp. Neurol. 391 (1998) 42-49
16. Golden J.P., Baloh R.H., Kotzbauer P.T., Lampe P.A., Osborne P.A., Milbrandt J., et al. Expression of neurturin, GDNF, and their receptors in the adult mouse CNS. J. Comp. Neurol. 398 (1998) 139-150
17. Gonzales R.A., Job M.O., and Doyon W.M. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacol. Ther. 103 (2004) 121-146
18. Granholm A.C., Reyland M., Albeck D., Sanders L., Gerhardt G., Hoernig G., et al. Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons. J. Neurosci. 20 (2000) 3182-3190
19. Green-Sadan T., Kinor N., Roth-Deri I., Geffen-Aricha R., Schindler C.J., and Yadid G. Transplantation of glial cell line-derived neurotrophic factor-expressing cells into the striatum and nucleus accumbens attenuates acquisition of cocaine self-administration in rats. Eur. J. Neurosci. 18 (2003) 2093-2098
20. Green-Sadan T., Kuttner Y., Lublin-Tennenbaum T., Kinor N., Boguslavsky Y., Margel S., et al. Glial cell line-derived neurotrophic factor-conjugated nanoparticles suppress acquisition of cocaine self-administration in rats. Exp. Neurol. 194 (2005) 97-105
21. He D.Y., McGough N.N., Ravindranathan A., Jeanblanc J., Logrip M.L., Phamluong K., et al. Glial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption. J. Neurosci. 25 (2005) 619-628
22. He D.Y., and Ron D. Autoregulation of glial cell line-derived neurotrophic factor expression: implications for the long-lasting actions of the anti-addiction drug, Ibogaine. FASEB J. 20 (2006) 2420-2422
23. He D.Y., and Ron D. GDNF reverses ethanol-mediated increases in tyrosine hydroxylase immunoreactivity via altering the activity of HSP90. J. Biol. Chem. 283 (2008) 8114-8119
24. Healey J.C., Winder D.G., and Kash T.L. Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions. Alcohol 42 (2008) 179-190
25. Hebert M.A., Van Horne C.G., Hoffer B.J., and Gerhardt G.A. Functional effects of GDNF in normal rat striatum: presynaptic studies using in vivo electrochemistry and microdialysis. J. Pharmacol. Exp. Ther. 279 (1996) 1181-1190
26. Hudson J., Granholm A.C., Gerhardt G.A., Henry M.A., Hoffman A., Biddle P., et al. Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo. Brain Res. Bull. 36 (1995) 425-432
27. Kobori N., Waymire J.C., Haycock J.W., Clifton G.L., and Dash P.K. Enhancement of tyrosine hydroxylase phosphorylation and activity by glial cell line-derived neurotrophic factor. J. Biol. Chem. 279 (2004) 2182-2191
28. Koob G.F. Alcoholism: allostasis and beyond. Alcohol Clin. Exp. Res. 27 (2003) 232-243
29. Koob G.F., and Le Moal M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24 (2001) 97-129
30. Kordower J.H., Emborg M.E., Bloch J., Ma S.Y., Chu Y., Leventhal L., et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290 (2000) 767-773
31. Kowsky S., Poppelmeyer C., Kramer E.R., Falkenburger B.H., Kruse A., Klein R., et al. RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 20049-20054
32. Lancaster F.E. Gender differences in the brain: implications for the study of human alcoholism. Alcohol Clin. Exp. Res. 18 (1994) 740-746
33. Lapchak P.A., Jiao S., Collins F., and Miller P.J. Glial cell line-derived neurotrophic factor: distribution and pharmacology in the rat following a bolus intraventricular injection. Brain Res. 747 (1997) 92-102
34. Lin L.F., Doherty D.H., Lile J.D., Bektesh S., and Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260 (1993) 1130-1132
35. Matsuo A., Nakamura S., and Akiguchi I. Immunohistochemical localization of glial cell line-derived neurotrophic factor family receptor alpha-1 in the rat brain: confirmation of expression in various neuronal systems. Brain Res. 859 (2000) 57-71
36. Messer C.J., Eisch A.J., Carlezon Jr. W.A., Whisler K., Shen L., Wolf D.H., et al. Role for GDNF in biochemical and behavioral adaptations to drugs of abuse. Neuron 26 (2000) 247-257
37. Moore M.W., Klein R.D., Farinas I., Sauer H., Armanini M., Phillips H., et al. Renal and neuronal abnormalities in mice lacking GDNF. Nature 382 (1996) 76-79
38. NIAAA (1989). Relapse and craving. NIAAA Alcohol Alert no. 6.
39. NIAAA. NIAAA Council approves definition of binge drinking. NIAAA Newsletter 3 (2004)
40. Niwa M., Nitta A., Shen L., Noda Y., and Nabeshima T. Involvement of glial cell line-derived neurotrophic factor in inhibitory effects of a hydrophobic dipeptide Leu-Ile on morphine-induced sensitization and rewarding effects. Behav. Brain Res. 179 (2007) 167-171
41. Niwa M., Nitta A., Yamada Y., Nakajima A., Saito K., Seishima M., et al. An inducer for glial cell line-derived neurotrophic factor and tumor necrosis factor-alpha protects against methamphetamine-induced rewarding effects and sensitization. Biol. Psychiatry 61 (2007) 890-901
42. Pascual A., Hidalgo-Figueroa M., Piruat J.I., Pintado C.O., Gomez-Diaz R., and Lopez-Barneo J. Absolute requirement of GDNF for adult catecholaminergic neuron survival. Nat. Neurosci. 11 (2008) 755-761
43. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates. 4th ed. (1998), Academic Press, San Diego
44. Pichel J.G., Shen L., Sheng H.Z., Granholm A.C., Drago J., Grinberg A., et al. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382 (1996) 73-76
45. Pochon N.A., Menoud A., Tseng J.L., Zurn A.D., and Aebischer P. Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization. Eur. J. Neurosci. 9 (1997) 463-471
46. Rehm J., Room R., Graham K., Monteiro M., Gmel G., and Sempos C.T. The relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: an overview. Addiction 98 (2003) 1209-1228
47. Ron D., and Janak P.H. GDNF and addiction. Rev. Neurosci. 16 (2005) 277-285
48. Rösner S., Leucht S., Lehert P., and Soyka M. Acamprosate supports abstinence, naltrexone prevents excessive drinking: evidence from a meta-analysis with unreported outcomes. J. Psychopharmacol. 22 (2008) 11-23
49. Sanchez M.P., Silos-Santiago I., Frisen J., He B., Lira S.A., and Barbacid M. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382 (1996) 70-73
50. Sariola H., and Saarma M. Novel functions and signaling pathways for GDNF. J. Cell Sci. 116 (2003) 3855-3862
51. Simms J.A., Steensland P., Medina B., Abernathy K.E., Chandler L.J., Wise R., et al. Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats. Alcohol Clin. Exp. Res. 32 (2008) 1816-1823
52. Stuber G.D., Hopf F.W., Hahn J., Cho S.L., Guillory A., and Bonci A. Voluntary ethanol intake enhances excitatory synaptic strength in the ventral tegmental area. Alcohol Clin. Exp. Res. 32 (2008) 1714-1720
53. Tomac A., Lindqvist E., Lin L.F., Ogren S.O., Young D., Hoffer B.J., and Olson L. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373 (1995) 335-339
54. Tomac A., Widenfalk J., Lin L.F., Kohno T., Ebendal T., Hoffer B.J., et al. Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 8274-8278
55. Trupp M., Belluardo N., Funakoshi H., and Ibanez C.F. Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS. J. Neurosci. 17 (1997) 3554-3567
56. Wang J., Chen G., Lu B., and Wu C.P. GDNF acutely potentiates Ca2+ channels and excitatory synaptic transmission in midbrain dopaminergic neurons. Neurosignals 12 (2003) 78-88
57. Weiss F., Lorang M.T., Bloom F.E., and Koob G. Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. J. Pharmacol. Exp. Ther. 267 (1993) 250-258
58. Weiss F., Parsons L.H., Schulteis G., Hyytia P., Lorang M.T., Bloom F.E., et al. Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats. J. Neurosci. 16 (1996) 3474-3485
59. Weiss F., and Porrino L.J. Behavioral neurobiology of alcohol addiction: recent advances and challenges. J. Neurosci. 22 (2002) 3332-3337
60. Wise R.A. Voluntary ethanol intake in rats following exposure to ethanol on various schedules. Psychopharmacologia 29 (1973) 203-210
61. Yan Y., Yamada K., Niwa M., Nagai T., Nitta A., and Nabeshima T. Enduring vulnerability to reinstatement of methamphetamine-seeking behavior in glial-cell-line-derived neurotrophic factor mutant mice. FASEB J. 21 (2007) 1994-2004
62. Yang F., Feng L., Zheng F., Johnson S.W., Du J., Shen L., et al. GDNF acutely modulates excitability and A-type K(+) channels in midbrain dopaminergic neurons. Nat. Neurosci. 4 (2001) 1071-1078
63. Zapata A., Gonzales R.A., and Shippenberg T.S. Repeated ethanol intoxication induces behavioral sensitization in the absence of a sensitized accumbens dopamine response in C57BL/6J and DBA/2J mice. Neuropsychopharmacology 31 (2006) 396-405