New analogues of agmatine with higher affinity to imidazoline receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 3, 2009, Pages 1009-1011

  Treder, Adam P ^a   Andruszkiewicz, Ryszard ^a   Zgoda, Włodzimierz ^b   Ford, Celeste ^c   Hudson, Alan L ^c  

^a GDANSK UNIVERSITY OF TECHNOLOGY   (Poland)

^b MEDICAL UNIVERSITY OF GDANSK   (Poland)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

2, I1, I2 receptors; Affinity studies; Agmatine analogues

Indexed keywords

4(5)(2 AMINOETHYL)IMIDAZOLINE DERIVATIVE; AGMATINE; AGMATINE DERIVATIVE; ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; IMIDAZOLINE I1 RECEPTOR; IMIDAZOLINE I2 RECEPTOR; IMIDAZOLINE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING ASSAY; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CYCLIZATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY; TECHNIQUE;

AGMATINE; CHEMISTRY, PHARMACEUTICAL; CLONIDINE; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; GUANIDINE; HUMANS; IMIDAZOLES; IMIDAZOLINE RECEPTORS; INHIBITORY CONCENTRATION 50; KINETICS; MODELS, CHEMICAL; PROTEIN BINDING; RECEPTORS, ADRENERGIC, ALPHA-2; RECOMBINANT FUSION PROTEINS;

EID: 58549096271     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.11.055     Document Type: Article

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