Are n-3 polyunsaturated fatty acids antiarrhythmic in the absence of ischemia? : EEEEditorial t"o: The role of n-3 PUFAs in preventing the arrhythmic risk in patients with idiopathic dilated cardiomyopa"thy by S. Nodari et al.

Cardiovascular Drugs and Therapy

Volumn 23, Issue 1, 2009, Pages 1-3

  Raitt, Meritt H ^a,b  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b P 3 CARD ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; AMIODARONE; CALCIUM CHANNEL; CATECHOLAMINE; CYTOKINE; FLECAINIDE; OMEGA 3 FATTY ACID; PLACEBO; POTASSIUM CHANNEL; SODIUM CHANNEL;

ANTIARRHYTHMIC ACTIVITY; CATECHOLAMINE BLOOD LEVEL; CLINICAL TRIAL; CONGESTIVE CARDIOMYOPATHY; CORONARY ARTERY DISEASE; DEFIBRILLATOR; DIET SUPPLEMENTATION; DOG; EDITORIAL; ESKIMO; EXERCISE; HEART ARRHYTHMIA; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART RATE VARIABILITY; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE FIBRILLATION; HOLTER MONITORING; HUMAN; IN VITRO STUDY; MORTALITY; NONHUMAN; PRIORITY JOURNAL; QRS COMPLEX; RISK REDUCTION; SEA FOOD; SUDDEN DEATH; T WAVE;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; CARDIOMYOPATHIES; CLINICAL TRIALS AS TOPIC; FATTY ACIDS, OMEGA-3; HUMANS; MYOCARDIAL ISCHEMIA; RISK FACTORS;

EID: 58549091114     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10557-008-6151-6     Document Type: Editorial

References (18)

1. Nodari S, Metra M, Milesi G, Manerba A, Cesana B, Gheorghiade M, et al. The role of n-3 PUFAs in preventing the arrhythmic risk in patients with idiopathic dilated cardiomyopathy. Cardiovasc Drugs Ther. 2009;23 (in press).
2. HO Bang J Dyerberg A Nielsen 1971 Plasma lipid and lipoprotein pattern in greenlandic west-coast Eskimos Lancet 297 1143 1146
3. YF Xiao JX Kang JP Morgan A Leaf 1995 Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rate ventricular myocytes Physiology (Bethesda) 92 11000 11004
4. E Honore J Barhanin B Attali F Lesage M Lazdunski 1994 External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids Proc Natl Acad Sci U S A 91 1937 1944
5. H Hazama T Nakajima M Asano 1998 Omega-3 polyunsaturated fatty acids-modulation of voltage-dependent L-type Ca2+ current in guinea-pig tracheal smooth muscle cells Eur J Pharmacol 355 257 266
6. S Danthi J Enyeart J Enyeart 2005 Modulation of native T-type calcium channels by omega-3 fatty acids Biochem Biophys Res Commun 327 485 493
7. PL McLennan TM Bridle MY Abeywardena JS Charnock 1993 Comparative efficacy of n-3 and n-6 polyunsaturated fatty acids in modulating ventricular fibrillation threshold in marmoset monkeys Am J Clin Nutr 58 666 669
8. GE Billman JX Kang A Leaf 1999 Prevention of sudden cardiac death by dietary pure omega-3 polyunsaturated fatty acids in dogs Circulation 99 2452 2457
9. CM Albert CH Hennekens CJ O'Donnell UA Ajani VJ Carey WC Willett 1998 Fish consumption and risk of sudden cardiac death JAMA 279 23 28
10. CM Albert H Campos MJ Stampfer 2002 Blood levels of long-chain n-3 fatty acids and the risk of sudden death N Engl J Med 346 1113 1118
11. DS Siscovick TE Raghunathan I King 1995 Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest JAMA 274 1363 1367
12. R Marchioli F Barzi E Bomba 2002 Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione Circulation 105 1897 1903
13. MH Raitt WE Connor C Morris 2005 Fish oil supplementation and risk of ventricular tachycardia and ventricular fibrillation in patients with implantable defibrillators: a randomized controlled trial JAMA 293 2884 2891
14. A Leaf CM Albert M Josephson 2005 Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake Circulation 112 2762 2768
15. IA Brouwer PL Zock AJ Camm 2006 Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial JAMA 295 2613 2619
16. DJA Jenkins AR Josse J Beyene 2008 Fish-oil supplementation in patients with implantable cardioverter defibrillators: a meta-analysis CMAJ 178 157 164
17. F Bogun T Crawford S Reich 2007 Radiofrequency ablation of frequent, idiopathic premature ventricular complexes: comparison with a control group without intervention Heart Rhythm 7 863 867
18. DS Echt PR Liebson LB Mitchell 1991 Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial N Engl J Med 324 781 788