Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria

International Journal for Parasitology

Volumn 39, Issue 3, 2009, Pages 363-370

  Miu, Jenny ^a   Ball, Helen J ^a   Mellor, Andrew L ^b   Hunt, Nicholas H ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Cerebral malaria; Indoleamine 2,3 dioxygenase; Kynurenic acid; Kynurenine pathway; Picolinic acid; Quinolinic acid; Tryptophan metabolism

Indexed keywords

INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE 1; KYNURENIC ACID; KYNURENINE; PICOLINIC ACID; QUINOLINIC ACID; UNCLASSIFIED DRUG;

ENZYME ACTIVITY; INHIBITION; MALARIA; NERVOUS SYSTEM; PROTOZOAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN MALARIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; FEMALE; MOUSE; NONHUMAN; RISK ASSESSMENT; RISK FACTOR;

ANIMALS; BRAIN; ENZYME INHIBITORS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; KYNURENIC ACID; KYNURENINE; KYNURENINE 3-MONOOXYGENASE; MALARIA, CEREBRAL; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; PICOLINIC ACIDS; QUINOLINIC ACID; RNA, MESSENGER; SULFONAMIDES; THIAZOLES; TRYPTOPHAN OXYGENASE;

MURINAE; MUS; PLASMODIUM FALCIPARUM;

EID: 58549084023     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2008.10.005     Document Type: Article

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