Effect of a selective COX-2 inhibitor on cell proliferation and apoptosis in human gastric cancer cell line BGC-823

Journal of Central South University (Medical Sciences)

Volumn 33, Issue 12, 2008, Pages 1123-1128

  Li, Qian ^a   Peng, Jie ^a   Zhang, Gui Ying ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Apoptosis; BGC 823 cell line; Celecoxib; Proliferation; Selective cyclooxygenase 2 inhibitor

Indexed keywords

CDKN1A PROTEIN, HUMAN; CELECOXIB; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLOOXYGENASE 2 INHIBITOR; FAS ANTIGEN; FAS PROTEIN, HUMAN; PYRAZOLE DERIVATIVE; SULFONAMIDE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECT; HUMAN; METABOLISM; PATHOLOGY; STOMACH TUMOR; TUMOR CELL LINE;

ANTIGENS, CD95; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLOOXYGENASE 2 INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; PYRAZOLES; STOMACH NEOPLASMS; SULFONAMIDES;

EID: 58449124671     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Smalley W E, DuBois R N. Colorectal cancer and nonsteroidal anti-inflammatory drugs [J]. Adv Pharmacol, 1997, 39:1-20.
2. XU Mei-hong, WU Kai-chun, WU Han-ping, et al. The inhibitory effect of nonsteroid anti-inflammatory drugs on gastric [J]. Chin J Dig, 2002, 22 (4):199-201.
3. LI Jian-ying, YU Jie-ping, LUO He-sheng, et al. Influence of selective cyclooxygenase-2 inhibitor on proliferation of human gastric cancer cell [J]. Chin J Cancer, 2002, 21 (6):625-629.
4. Taketo M M. Cyclooxygenase-2 inhibitors in tumorigenesis (part 1) [J]. J Natl Cancer Inst, 1998, 90 (20):1529-1536.
5. Beauséjour C M, Krtolica A, Galimi F, et al. Reversal of human cellular senescence: roles of the p53 and p16 pathways[J]. EMBO J, 2003, 22 (16):4212-4222.
6. Alexander K, Yang H S, Hinds P W. pRb inactivation in senescent cells leads to an E2F-dependent apoptosis requiring p73 [J]. Mol Cancer Res, 2003, 1 (10):716-728.
7. Herbig U, Jobling W A, Chen B P, et al. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21 (CIP1), but not p16 (INK4a) [J]-Mol Cell, 2004, 14 (4):501-513.
8. ZHU Qiang, DENG Chang-sheng. The role of Fas/Fas ligand in tumorgenesis, immune escape, and counterattack in colonic cancer [J] . Chin J Int Med, 2002, 41 (6):378-380.
9. Ohno S, Tachibana M, Shibakita M, et al. Prognostic significance of Fas and FasL ligand system - associated apoptosis in gastric cancer [J]. Ann Surg Oncol, 2000, 7 (10):750-757.
10. Lee T B, Min Y D, Lim C, et al. Fas (Apo-1/CD95) and Fas ligand interaction between gastric cancer cells and immune cells [J]. J Gastrolenterol Hepatol, 2002, 17 (1):32-38.