Quantitative proof of liquid penetration-involved granule formation in a high shear mixer

Powder Technology

Volumn 189, Issue 2, 2009, Pages 165-171

  van den Dries, Kaspar ^a   Vromans, Herman ^a,b  

^a NV ORGANON   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Granule breakage; High shear granulation; Liquid penetration; Nucleation; Viscosity

Indexed keywords

BINDER DISPERSIONS; BROKEN DOWNS; EXTREME CONDITIONS; GRANULE BREAKAGE; GRANULE FORMATIONS; HIGH SHEAR GRANULATION; LIQUID PENETRATION; LOW VISCOSITIES; MODEL-BASED; NUCLEATION MECHANISMS; POWDER MIXTURES;

BINDERS; HYDRODYNAMICS; LIQUEFIED GASES; LIQUID NITROGEN; MIXERS (MACHINERY); NUCLEATION; SUGARS; VISCOSITY;

GRANULATION;

LACTOSE; LIQUID NITROGEN;

ARTICLE; DISPERSION; DRUG GRANULATION; DRUG GRANULE; FREEZING; LIQUID; LIQUID PENETRATION; MIXER; NUCLEATION; PHYSICAL PHENOMENA; POWDER; VISCOSITY;

EID: 58349116043     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2008.04.007     Document Type: Article

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