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Volumn 32, Issue 1, 2009, Pages 37-46

Alpha-lipoic acid improves acetic acid-induced gastric ulcer healing in rats

Author keywords

Acetic acid; Alpha lipoic acid; Apoptosis; Oxidant damage; Ulcer healing

Indexed keywords

ACETIC ACID; GLUTATHIONE; MYELOPEROXIDASE; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE; THIOCTIC ACID;

EID: 58349106683     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10753-008-9100-4     Document Type: Article
Times cited : (21)

References (51)
  • 1
    • 0031404913 scopus 로고    scopus 로고
    • Is smoking still important in the pathogenesis of peptic ulcer disease?
    • doi:10.1097/00004836-199700001-00003
    • G. L. Eastwood 1997 Is smoking still important in the pathogenesis of peptic ulcer disease? J Clin Gastroenterol. 25 S1 S7 doi:10.1097/00004836- 199700001-00003
    • (1997) J Clin Gastroenterol. , vol.25
    • Eastwood, G.L.1
  • 3
    • 25644437787 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of gastrointestinal ulcer healing
    • doi:10.1007/s10620-005-2803-6
    • A. S. Tarnawski 2005 Cellular and molecular mechanisms of gastrointestinal ulcer healing Dig Dis Sci. 50 S24 S33 doi:10.1007/s10620-005- 2803-6
    • (2005) Dig Dis Sci. , vol.50
    • Tarnawski, A.S.1
  • 4
    • 0033134603 scopus 로고    scopus 로고
    • The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor-and MAP kinase-dependent interregulation
    • doi:10.1172/JCI3304
    • D. Taupin D. C. Wu W. K. Jeon K. Devaney T. C. Wang D. K. Podolsky 1999 The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor-and MAP kinase-dependent interregulation J Clin Invest. 103 R31 R38 doi:10.1172/JCI3304
    • (1999) J Clin Invest. , vol.103
    • Taupin, D.1    Wu, D.C.2    Jeon, W.K.3    Devaney, K.4    Wang, T.C.5    Podolsky, D.K.6
  • 5
    • 0034030123 scopus 로고    scopus 로고
    • Peptide gene expression in gastrointestinal mucosal ulceration: Ordered sequence or redundancy?
    • doi:10.1136/gut.46.2.286
    • W. M. Wong R. J. Playford N. A. Wright 2000 Peptide gene expression in gastrointestinal mucosal ulceration: ordered sequence or redundancy? Gut. 46 286 292 doi:10.1136/gut.46.2.286
    • (2000) Gut. , vol.46 , pp. 286-292
    • Wong, W.M.1    Playford, R.J.2    Wright, N.A.3
  • 6
    • 18244419816 scopus 로고    scopus 로고
    • Estradiol treatment ameliorates acetic acid-induced gastric and colonic injuries in rats
    • doi:10.1023/B:IFLA.0000006703.53427.da
    • O. Günal B. K. Oktar E. Ozçinar M. Sungur S. Arbak B. Yeǧen 2003 Estradiol treatment ameliorates acetic acid-induced gastric and colonic injuries in rats Inflammation. 27 351 359 doi:10.1023/B:IFLA. 0000006703.53427.da
    • (2003) Inflammation. , vol.27 , pp. 351-359
    • Günal, O.1    Oktar, B.K.2    Ozçinar, E.3    Sungur, M.4    Arbak, S.5    Yeǧen, B.6
  • 7
    • 25844492001 scopus 로고    scopus 로고
    • An overview of acetic acid ulcer models-the history and state of the art of peptic ulcer research
    • doi:10.1248/bpb.28.1321
    • S. Okabe K. Amagase 2005 An overview of acetic acid ulcer models-the history and state of the art of peptic ulcer research Biol Pharm Bull. 28 1321 1341 doi:10.1248/bpb.28.1321
    • (2005) Biol Pharm Bull. , vol.28 , pp. 1321-1341
    • Okabe, S.1    Amagase, K.2
  • 8
    • 0034666260 scopus 로고    scopus 로고
    • The cytotoxic lipid peroxidation product, 4-hydroxy-2-nonenal, pecifically inhibits decarboxylating dehydrogenases in the matrix of plant mitochondria
    • doi:10.1016/S0014-5793(00)01976-1
    • A. H. Millar C. J. Leaver 2000 The cytotoxic lipid peroxidation product, 4-hydroxy-2-nonenal, pecifically inhibits decarboxylating dehydrogenases in the matrix of plant mitochondria FEBS Lett. 481 117 121 doi:10.1016/S0014-5793(00) 01976-1
    • (2000) FEBS Lett. , vol.481 , pp. 117-121
    • Millar, A.H.1    Leaver, C.J.2
  • 9
    • 0031605517 scopus 로고    scopus 로고
    • From lipoic acid to multi-enzyme complexes
    • L. Reed 1998 From lipoic acid to multi-enzyme complexes Protein Sci. 7 220 224
    • (1998) Protein Sci. , vol.7 , pp. 220-224
    • Reed, L.1
  • 10
    • 0030768236 scopus 로고    scopus 로고
    • The pharmacology of the antioxidant lipoic acid
    • doi:10.1016/S0306-3623(96)00474-0
    • G. P. Biewenga G. R. Haenen A. Bast 1997 The pharmacology of the antioxidant lipoic acid Gen Pharmacol. 29 315 331 doi:10.1016/S0306-3623(96) 00474-0
    • (1997) Gen Pharmacol. , vol.29 , pp. 315-331
    • Biewenga, G.P.1    Haenen, G.R.2    Bast, A.3
  • 11
    • 0029070687 scopus 로고
    • Alpha-lipoic acid as a biological antioxidant
    • doi:10.1016/0891-5849(95)00017-R
    • L. Packer E. H. Witt H. J. Tritschler 1995 Alpha-lipoic acid as a biological antioxidant Free Radic Biol Med. 19 227 250 doi:10.1016/0891-5849(95) 00017-R
    • (1995) Free Radic Biol Med. , vol.19 , pp. 227-250
    • Packer, L.1    Witt, E.H.2    Tritschler, H.J.3
  • 12
    • 33344476096 scopus 로고    scopus 로고
    • Mitochondrial membrane damage during aging process in rat heart: Potential efficacy of l-carnitine and dl-alpha-lipoic acid
    • doi:10.1016/j.mad.2005.12.004
    • S. Savitha C. Panneerselvam 2006 Mitochondrial membrane damage during aging process in rat heart: potential efficacy of l-carnitine and dl-alpha-lipoic acid Mech Ageing Dev. 127 349 355 doi:10.1016/j.mad.2005.12.004
    • (2006) Mech Ageing Dev. , vol.127 , pp. 349-355
    • Savitha, S.1    Panneerselvam, C.2
  • 14
    • 21444439237 scopus 로고    scopus 로고
    • Molecular targets of diabetic vascular complications and potential new drugs
    • doi:10.2174/1389450054021855
    • R. Da Ros R. Assaloni A. Ceriello 2005 Molecular targets of diabetic vascular complications and potential new drugs Curr Drug Targets 6 503 509 doi:10.2174/1389450054021855
    • (2005) Curr Drug Targets , vol.6 , pp. 503-509
    • Da Ros, R.1    Assaloni, R.2    Ceriello, A.3
  • 15
    • 28844481889 scopus 로고    scopus 로고
    • Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury
    • doi:10.1089/ars.2005.7.1494
    • A. M. Vincent M. J. Stevens C. Backus L. L. McLean E. L. Feldman 2005 Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury Antioxid Redox Signal. 7 1494 506 doi:10.1089/ars.2005.7.1494
    • (2005) Antioxid Redox Signal. , vol.7 , pp. 1494-506
    • Vincent, A.M.1    Stevens, M.J.2    Backus, C.3    McLean, L.L.4    Feldman, E.L.5
  • 16
    • 9644308047 scopus 로고    scopus 로고
    • Prevention and treatment of macroangiopathy: Focusing on oxidative stress
    • doi:10.1016/j.diabres.2003.08.017
    • K. G. Park M. J. Kim H. S. Kim S. J. Lee D. K. Song I. K. Lee 2004 Prevention and treatment of macroangiopathy: focusing on oxidative stress Diabetes Res Clin Pract. 66 S57 S62 doi:10.1016/j.diabres.2003.08.017
    • (2004) Diabetes Res Clin Pract. , vol.66
    • Park, K.G.1    Kim, M.J.2    Kim, H.S.3    Lee, S.J.4    Song, D.K.5    Lee, I.K.6
  • 18
    • 0037047476 scopus 로고    scopus 로고
    • Alpha-lipoic acid prevents ethanol-induced protein oxidation in mouse hippocampal HT22 cells
    • doi:10.1016/S0304-3940(02)00415-9
    • M. Pirlich K. Kiok G. Sandig H. Lochs T. Grune 2002 Alpha-lipoic acid prevents ethanol-induced protein oxidation in mouse hippocampal HT22 cells Neurosci Lett. 328 93 96 doi:10.1016/S0304-3940(02)00415-9
    • (2002) Neurosci Lett. , vol.328 , pp. 93-96
    • Pirlich, M.1    Kiok, K.2    Sandig, G.3    Lochs, H.4    Grune, T.5
  • 19
    • 34748921578 scopus 로고    scopus 로고
    • Protective effects of l-carnitine and alpha-lipoic acid in rats with adjuvant arthritis
    • doi:10.1016/j.phrs.2007.07.008
    • N. Tastekin N. Aydogdu D. Dokmeci U. Usta M. Birtane H. Erbas M. Ture 2007 Protective effects of l-carnitine and alpha-lipoic acid in rats with adjuvant arthritis Pharmacol Res. 56 303 310 doi:10.1016/j.phrs.2007.07.008
    • (2007) Pharmacol Res. , vol.56 , pp. 303-310
    • Tastekin, N.1    Aydogdu, N.2    Dokmeci, D.3    Usta, U.4    Birtane, M.5    Erbas, H.6    Ture, M.7
  • 20
    • 11844304362 scopus 로고    scopus 로고
    • The protective effect of alpha-lipoic acid against oxidative damage in rabbit conjunctiva and cornea exposed to ultraviolet radiation
    • doi:10.1159/000081783
    • U. Demir T. Demir N. Ilhan 2005 The protective effect of alpha-lipoic acid against oxidative damage in rabbit conjunctiva and cornea exposed to ultraviolet radiation Ophthalmologica. 219 49 53 doi:10.1159/000081783
    • (2005) Ophthalmologica. , vol.219 , pp. 49-53
    • Demir, U.1    Demir, T.2    Ilhan, N.3
  • 21
    • 33644664987 scopus 로고    scopus 로고
    • Lipoic acid-the drug of the future?
    • A. Bilska L. Włodek 2005 Lipoic acid-the drug of the future? Pharmacol Rep. 57 570 577
    • (2005) Pharmacol Rep. , vol.57 , pp. 570-577
    • Bilska, A.1    Włodek, L.2
  • 22
    • 38749127956 scopus 로고    scopus 로고
    • Antioxidant effect of alpha-lipoic acid against ethanol-induced gastric mucosal erosion in rats
    • doi:10.1159/000111145
    • O. Sehirli E. Tatlidede M. Yüksel C. Erzik S. Cetinel B. C. Yeǧen G. Sener 2008 Antioxidant effect of alpha-lipoic acid against ethanol-induced gastric mucosal erosion in rats Pharmacology. 81 173 180 doi:10.1159/000111145
    • (2008) Pharmacology. , vol.81 , pp. 173-180
    • Sehirli, O.1    Tatlidede, E.2    Yüksel, M.3    Erzik, C.4    Cetinel, S.5    Yeǧen, B.C.6    Sener, G.7
  • 23
    • 14244263607 scopus 로고    scopus 로고
    • Protective effect of dl-alpha-lipoic acid in cyclophosphamide induced oxidative injury in rat testis
    • doi:10.1016/j.reprotox.2004.06.015
    • E. Selvakumar C. Prahalathan Y. Mythili P. Varalakshmi 2004 Protective effect of dl-alpha-lipoic acid in cyclophosphamide induced oxidative injury in rat testis Reprod Toxicol. 19 163 7 doi:10.1016/j.reprotox.2004.06.015
    • (2004) Reprod Toxicol. , vol.19 , pp. 163-7
    • Selvakumar, E.1    Prahalathan, C.2    Mythili, Y.3    Varalakshmi, P.4
  • 24
    • 31144477008 scopus 로고    scopus 로고
    • Protective effect of lipoic acid on micronuclei induction by cyclophosphamide
    • doi:10.1007/s00204-005-0015-7
    • E. Selvakumar C. Prahalathan P. T. Sudharsan P. Varalakshmi 2006 Protective effect of lipoic acid on micronuclei induction by cyclophosphamide Arch Toxicol. 80 115 119 doi:10.1007/s00204-005-0015-7
    • (2006) Arch Toxicol. , vol.80 , pp. 115-119
    • Selvakumar, E.1    Prahalathan, C.2    Sudharsan, P.T.3    Varalakshmi, P.4
  • 25
    • 0015362625 scopus 로고
    • Chronicity of acetic acid ulcer in the rat stomach
    • doi:10.1007/BF02231748
    • S. Okabe C. J. Pfeiffer 1972 Chronicity of acetic acid ulcer in the rat stomach Am J Dig Dis. 17 619 629 doi:10.1007/BF02231748
    • (1972) Am J Dig Dis. , vol.17 , pp. 619-629
    • Okabe, S.1    Pfeiffer, C.J.2
  • 26
    • 0015023481 scopus 로고
    • A method for experimental, penetrating gastric and duodenal ulcers in rats. Observations on normal healing
    • doi:10.1007/BF02235252
    • S. Okabe J. L. Roth C. J. Pfeiffer 1971 A method for experimental, penetrating gastric and duodenal ulcers in rats. Observations on normal healing Am J Dig Dis. 16 277 284 doi:10.1007/BF02235252
    • (1971) Am J Dig Dis. , vol.16 , pp. 277-284
    • Okabe, S.1    Roth, J.L.2    Pfeiffer, C.J.3
  • 27
    • 0035666883 scopus 로고    scopus 로고
    • Estrogens ameliorate remote organ inflammation induced by burn injury in rats
    • doi:10.1007/PL00000238
    • E. S. Ozveri A. Bozkurt G. Haklar S. Cetinel S. Arbak C. Yeǧen B. C. Yeǧen 2001 Estrogens ameliorate remote organ inflammation induced by burn injury in rats Inflamm Res. 50 585 591 doi:10.1007/PL00000238
    • (2001) Inflamm Res. , vol.50 , pp. 585-591
    • Ozveri, E.S.1    Bozkurt, A.2    Haklar, G.3    Cetinel, S.4    Arbak, S.5    Yeǧen, C.6    Yeǧen, B.C.7
  • 28
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • doi:10.1038/284555a0
    • A. H. Wyllie 1980 Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation Nature 284 555 556 doi:10.1038/284555a0
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 29
    • 6544229829 scopus 로고
    • A study of the conditions and mechanism of the diphenylamine reaction for the calorimetric estimation of deoxyribonucleic acid
    • K. Burton 1956 A study of the conditions and mechanism of the diphenylamine reaction for the calorimetric estimation of deoxyribonucleic acid Biochem J. 62 315 323
    • (1956) Biochem J. , vol.62 , pp. 315-323
    • Burton, K.1
  • 30
    • 0020051148 scopus 로고
    • Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker
    • doi:10.1111/1523-1747.ep12506462
    • P. P. Bradley D. A. Priebat R. D. Christensen G. Rothstein 1982 Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker J Invest Dermatol. 78 206 209 doi:10.1111/1523-1747.ep12506462
    • (1982) J Invest Dermatol. , vol.78 , pp. 206-209
    • Bradley, P.P.1    Priebat, D.A.2    Christensen, R.D.3    Rothstein, G.4
  • 32
    • 0026492867 scopus 로고
    • Mucosal reactive oxygen metabolite production in duodenal ulcer disease
    • doi:10.1136/gut.33.11.1467
    • G. R. Davies N. J. Simmonds T. R. Stevens A. Grandison D. R. Blake D. S. Rampton 1992 Mucosal reactive oxygen metabolite production in duodenal ulcer disease Gut. 33 1467 1472 doi:10.1136/gut.33.11.1467
    • (1992) Gut. , vol.33 , pp. 1467-1472
    • Davies, G.R.1    Simmonds, N.J.2    Stevens, T.R.3    Grandison, A.4    Blake, D.R.5    Rampton, D.S.6
  • 33
    • 0021871166 scopus 로고
    • The effect of chronic ethanol ingestion on hepatic lipid peroxide, glutathione, glutathione peroxidase and glutathione transferase in rats
    • doi:10.1016/0300-483X(85)90008-3
    • G. Aykac M. Uysal A. S. Yalcin N. Koçak-Toker A. Sivas H. Öz 1985 The effect of chronic ethanol ingestion on hepatic lipid peroxide, glutathione, glutathione peroxidase and glutathione transferase in rats Toxicology 36 71 76 doi:10.1016/0300-483X(85)90008-3
    • (1985) Toxicology , vol.36 , pp. 71-76
    • Aykac, G.1    Uysal, M.2    Yalcin, A.S.3    Koçak-Toker, N.4    Sivas, A.5    Öz, H.6
  • 34
  • 35
    • 0031026997 scopus 로고    scopus 로고
    • Role of rebamipide on induction of heat-shock proteins and protection against reactive oxygen metabolite-mediated cell damage in cultured gastric mucosal cells
    • doi:10.1016/S0891-5849(96)00406-6
    • K. B. Hahm I. S. Park Y. S. Kim J. H. Kim S. W. Cho S. I. Lee J. K. Youn 1997 Role of rebamipide on induction of heat-shock proteins and protection against reactive oxygen metabolite-mediated cell damage in cultured gastric mucosal cells Free Radic Biol Med. 22 711 716 doi:10.1016/S0891-5849(96)00406-6
    • (1997) Free Radic Biol Med. , vol.22 , pp. 711-716
    • Hahm, K.B.1    Park, I.S.2    Kim, Y.S.3    Kim, J.H.4    Cho, S.W.5    Lee, S.I.6    Youn, J.K.7
  • 36
    • 0033231196 scopus 로고    scopus 로고
    • Comparison of the effect of alpha-lipoic acid and alpha-tocopherol supplementation on measures of oxidative stress
    • doi:10.1016/S0891-5849(99)00155-0
    • K. Arangon S. Deveraj O. Tirosh L. Packer I. Jialal 1999 Comparison of the effect of alpha-lipoic acid and alpha-tocopherol supplementation on measures of oxidative stress Free Radic Biol Med. 27 1114 1121 doi:10.1016/S0891- 5849(99)00155-0
    • (1999) Free Radic Biol Med. , vol.27 , pp. 1114-1121
    • Arangon, K.1    Deveraj, S.2    Tirosh, O.3    Packer, L.4    Jialal, I.5
  • 37
    • 48849114553 scopus 로고    scopus 로고
    • Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity
    • doi:10.1002/iub.40
    • K. Petersen Shay R. F. Moreau E. J. Smith T. M. Hagen 2008 Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity IUBMB Life 60 362 367 doi:10.1002/iub.40
    • (2008) IUBMB Life , vol.60 , pp. 362-367
    • Petersen Shay, K.1    Moreau, R.F.2    Smith, E.J.3    Hagen, T.M.4
  • 38
    • 33746862219 scopus 로고    scopus 로고
    • Reversing gastric mucosal alterations during ethanol-induced chronic gastritis in rats by oral administration of Opuntia ficus-indica mucilage
    • R. Vázquez-Ramírez M. Olguín-Martínez C. Kubli-Garfias R. Hernández-Muñoz 2006 Reversing gastric mucosal alterations during ethanol-induced chronic gastritis in rats by oral administration of Opuntia ficus-indica mucilage World J Gastroenterol. 12 4318 4324
    • (2006) World J Gastroenterol. , vol.12 , pp. 4318-4324
    • Vázquez-Ramírez, R.1    Olguín-Martínez, M.2    Kubli-Garfias, C.3    Hernández-Muñoz, R.4
  • 39
    • 33846082831 scopus 로고    scopus 로고
    • Oxidative stress involvement and gene expression in indomethacin-induced gastropathy
    • doi:10.1179/135100006X155021
    • Y. Naito T. Yoshikawa 2006 Oxidative stress involvement and gene expression in indomethacin-induced gastropathy Redox Rep. 11 243 253 doi:10.1179/135100006X155021
    • (2006) Redox Rep. , vol.11 , pp. 243-253
    • Naito, Y.1    Yoshikawa, T.2
  • 40
    • 0027934852 scopus 로고
    • Lipoic acid favors thiolsulfinate formation after hypochlorous acid scavenging: A study with lipoic acid derivatives
    • doi:10.1006/abbi.1994.1288
    • G. Biewenga J. de Jong A. Bast 1994 Lipoic acid favors thiolsulfinate formation after hypochlorous acid scavenging: a study with lipoic acid derivatives Arch Biochem Biophys. 312 114 120 doi:10.1006/abbi.1994.1288
    • (1994) Arch Biochem Biophys. , vol.312 , pp. 114-120
    • Biewenga, G.1    De Jong, J.2    Bast, A.3
  • 41
    • 0018628604 scopus 로고
    • High concentrations of glutathione in glandular stomach: Possible implications for carcinogenesis
    • doi:10.1126/science.572989
    • S. C. Boyd H. A. Sasame M. R. Boyd 1979 High concentrations of glutathione in glandular stomach: possible implications for carcinogenesis Science 205 1010 1012 doi:10.1126/science.572989
    • (1979) Science , vol.205 , pp. 1010-1012
    • Boyd, S.C.1    Sasame, H.A.2    Boyd, M.R.3
  • 42
    • 0032874845 scopus 로고    scopus 로고
    • Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defense against oxidative stress
    • doi:10.1080/10715769900300851
    • J. D. Hayes L. I. McLellan 1999 Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defense against oxidative stress Free Radic Res. 31 273 300 doi:10.1080/10715769900300851
    • (1999) Free Radic Res. , vol.31 , pp. 273-300
    • Hayes, J.D.1    McLellan, L.I.2
  • 43
    • 0033947733 scopus 로고    scopus 로고
    • Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions
    • doi:10.1016/S0378-8741(99)00174-9
    • C. La Casa I. Villegas C. Alarcón de la Lastra V. Motilva M. J. Martín Calero 2000 Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions J Ethnopharmacol. 71 45 53 doi:10.1016/S0378-8741(99)00174-9
    • (2000) J Ethnopharmacol. , vol.71 , pp. 45-53
    • La Casa, C.1    Villegas, I.2    Lastra De La C.Alarcón3    Motilva, V.4    Martín Calero, M.J.5
  • 44
    • 33751180574 scopus 로고    scopus 로고
    • Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation
    • doi:10.1124/jpet.106.110965
    • J. Moungjaroen U. Nimmannit P. S. Callery L. Wang N. Azad V. Lipipun P. Chanvorachote Y. Rojanasakul 2006 Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation J Pharmacol Exp Ther. 319 1062 1069 doi:10.1124/jpet.106.110965
    • (2006) J Pharmacol Exp Ther. , vol.319 , pp. 1062-1069
    • Moungjaroen, J.1    Nimmannit, U.2    Callery, P.S.3    Wang, L.4    Azad, N.5    Lipipun, V.6    Chanvorachote, P.7    Rojanasakul, Y.8
  • 45
    • 43549122067 scopus 로고    scopus 로고
    • Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway
    • doi:10.1016/j.febslet.2008.04.021
    • D. Y. Shi H. L. Liu J. S. Stern P. Z. Yu S. L. Liu 2008 Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway FEBS Lett. 582 1667 1671 doi:10.1016/j.febslet.2008.04.021
    • (2008) FEBS Lett. , vol.582 , pp. 1667-1671
    • Shi, D.Y.1    Liu, H.L.2    Stern, J.S.3    Yu, P.Z.4    Liu, S.L.5
  • 47
    • 33847658343 scopus 로고    scopus 로고
    • Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity
    • H. S. Kim H. J. Kim K. G. Park Y. N. Kim T. K. Kwon J. Y. Park K. U. Lee J. G. Kim I. K. Lee 2007 Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity Exp Mol Med. 39 106 113
    • (2007) Exp Mol Med. , vol.39 , pp. 106-113
    • Kim, H.S.1    Kim, H.J.2    Park, K.G.3    Kim, Y.N.4    Kwon, T.K.5    Park, J.Y.6    Lee, K.U.7    Kim, J.G.8    Lee, I.K.9
  • 48
    • 25844459154 scopus 로고    scopus 로고
    • NF-κB: Linking inflammation and immunity to cancer development and progression
    • doi:10.1038/nri1703
    • M. Karin F. R. Greten 2005 NF-κB: Linking inflammation and immunity to cancer development and progression Nat Rev Immunol. 5 749 759 doi:10.1038/nri1703
    • (2005) Nat Rev Immunol. , vol.5 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 49
    • 0035158577 scopus 로고    scopus 로고
    • Alpha-lipoic acid inhibits TNF-alpha induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells
    • doi:10.1096/fj.01-0260com
    • W. J. Zhang B. Frei 2001 Alpha-lipoic acid inhibits TNF-alpha induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells FASEB J. 15 2423 2432 doi:10.1096/fj.01-0260com
    • (2001) FASEB J. , vol.15 , pp. 2423-2432
    • Zhang, W.J.1    Frei, B.2
  • 50
    • 0036125180 scopus 로고    scopus 로고
    • Effect of alpha-lipoic acid on lipid peroxidation and anti-oxidant enzyme activities in diabetic rats
    • doi:10.1046/j.1440-1681.2002.03642.x
    • Y. Dinçer A. Telci R. Kayali I. A. Yilmaz U. Cakatay T. Akçay 2002 Effect of alpha-lipoic acid on lipid peroxidation and anti-oxidant enzyme activities in diabetic rats Clin Exp Pharmacol Physiol. 29 281 284 doi:10.1046/j.1440-1681.2002.03642.x
    • (2002) Clin Exp Pharmacol Physiol. , vol.29 , pp. 281-284
    • Dinçer, Y.1    Telci, A.2    Kayali, R.3    Yilmaz, I.A.4    Cakatay, U.5    Akçay, T.6
  • 51
    • 16344377076 scopus 로고    scopus 로고
    • Short-term hyperglycemia produces oxidative damage and apoptosis in neurons
    • A. M. Vincent L. L. McLean C. Backus E. L. Feldman 2005 Short-term hyperglycemia produces oxidative damage and apoptosis in neurons FASEB J. 19 638 640
    • (2005) FASEB J. , vol.19 , pp. 638-640
    • Vincent, A.M.1    McLean, L.L.2    Backus, C.3    Feldman, E.L.4


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