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Volumn 33, Issue 10, 2008, Pages 844-860

Idronoxil. Proapoptotic agent, oncolytic

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CARBOPLATIN; CISPLATIN; CYCLODEXTRIN; DOXORUBICIN; FURAFYLLINE; GEMCITABINE; IDRONOXIL; KETOCONAZOLE; METOCLOPRAMIDE; NV 06; PACLITAXEL; PLACEBO; PLATINUM COMPLEX; PROMETHAZINE; QUERCETIN; QUINIDINE; SULFAPHENAZOLE; TAXANE DERIVATIVE; TOPOTECAN; TRANYLCYPROMINE; UNCLASSIFIED DRUG;

EID: 58349098355     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.2008.33.10.1260120     Document Type: Article
Times cited : (6)

References (35)
  • 1
    • 13844297030 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by polyphenols: Evidence from laboratory investigations
    • Lambert, J.D., Hong, J., Yang, G.Y. et al. Inhibition of carcinogenesis by polyphenols: Evidence from laboratory investigations. Am J Clin Nutr 2005, 81(1, Suppl.): 284S-91S.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1 and SUPPL.
    • Lambert, J.D.1    Hong, J.2    Yang, G.Y.3
  • 2
    • 13844271387 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
    • Williamson, G., Manach, C. Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am J Clin Nutr 2005, 81(1, Suppl.): 243S-55S.
    • (2005) Am J Clin Nutr , vol.81 , Issue.1 and SUPPL.
    • Williamson, G.1    Manach, C.2
  • 3
    • 56149125452 scopus 로고    scopus 로고
    • Apoptosis by dietary agents for prevention and treatment of cancer
    • Epub ahead of print
    • Khan, N., Adhami, V.M., Mukhtar, H. Apoptosis by dietary agents for prevention and treatment of cancer. Biochem Pharmacol 2008, Epub ahead of print.
    • (2008) Biochem Pharmacol
    • Khan, N.1    Adhami, V.M.2    Mukhtar, H.3
  • 4
    • 38449107684 scopus 로고    scopus 로고
    • Cell cycle control as a basis for cancer chemoprevention through dietary agents
    • Meeran, S.M., Katiyar, S.K. Cell cycle control as a basis for cancer chemoprevention through dietary agents. Front Biosci 2008, 13: 2191-202.
    • (2008) Front Biosci , vol.13 , pp. 2191-2202
    • Meeran, S.M.1    Katiyar, S.K.2
  • 5
    • 44049092395 scopus 로고    scopus 로고
    • The dark side of a tumor suppressor: Antiapoptotic p53
    • Jänicke, R. U., Sohn, D., Schulze-Osthoff, K. The dark side of a tumor suppressor: Antiapoptotic p53. Cell Death Differ 2008, 15(6): 959-76.
    • (2008) Cell Death Differ , vol.15 , Issue.6 , pp. 959-976
    • Jänicke, R.U.1    Sohn, D.2    Schulze-Osthoff, K.3
  • 6
    • 48449100702 scopus 로고    scopus 로고
    • Downregulating sphingosine kinase-1 for cancer therapy
    • Cuvillier, O. Downregulating sphingosine kinase-1 for cancer therapy. Expert Opin Ther Targets 2008, 2(8): 1009-20.
    • (2008) Expert Opin Ther Targets , vol.2 , Issue.8 , pp. 1009-1020
    • Cuvillier, O.1
  • 7
    • 55349140730 scopus 로고    scopus 로고
    • Anti-tumor activity of phenoxodiol: From bench to clinic
    • Alvero, A.B., Kelly, M., Rossi, P. Anti-tumor activity of phenoxodiol: From bench to clinic. Fut Oncol 2008, 4(4): 475-82.
    • (2008) Fut Oncol , vol.4 , Issue.4 , pp. 475-482
    • Alvero, A.B.1    Kelly, M.2    Rossi, P.3
  • 8
    • 31544466555 scopus 로고    scopus 로고
    • Molecular mechanism of phenoxodiol-induced apoptosis in ovarian carcinoma cells
    • Alvero, A.B., O'Malley, D., Brown, D. et al. Molecular mechanism of phenoxodiol-induced apoptosis in ovarian carcinoma cells. Cancer 2006, 106(3): 599-608.
    • (2006) Cancer , vol.106 , Issue.3 , pp. 599-608
    • Alvero, A.B.1    O'Malley, D.2    Brown, D.3
  • 9
    • 0037854571 scopus 로고    scopus 로고
    • Phenoxodiol - an isoflavone analog - induces apoptosis in chemoresistant ovarian cancer cells
    • Kamsteeg, M., Rutherford, T., Sapi, E. at al. Phenoxodiol - an isoflavone analog - induces apoptosis in chemoresistant ovarian cancer cells. Oncogene 2003, 22(17): 2611-20.
    • (2003) Oncogene , vol.22 , Issue.17 , pp. 2611-2620
    • Kamsteeg, M.1    Rutherford, T.2    Sapi, E.3    at al4
  • 10
    • 33846973344 scopus 로고    scopus 로고
    • Kluger, H.M., McCarthy, M.M., Alvero, A.B. et al. The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by phenoxodiol is associated with carboplatin sensitization. J Transl Mad 2007, 5: 6-20.
    • Kluger, H.M., McCarthy, M.M., Alvero, A.B. et al. The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by phenoxodiol is associated with carboplatin sensitization. J Transl Mad 2007, 5: 6-20.
  • 11
    • 0036765743 scopus 로고    scopus 로고
    • Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific
    • Baudhuin, L.M., Cristina, K.L., Ju, J. et al. Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific. Mol Pharmacol 2002, 62(3): 660-71.
    • (2002) Mol Pharmacol , vol.62 , Issue.3 , pp. 660-671
    • Baudhuin, L.M.1    Cristina, K.L.2    Ju, J.3
  • 12
    • 0038447079 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate promotes mouse melanocyte survival via ERK and Akt activation
    • Kim, D.S., Hwang, E.S., Lee, J.E., Kim, S.Y., Park, K.C. Sphingosine-1-phosphate promotes mouse melanocyte survival via ERK and Akt activation. Cell Signal 2003, 15(10): 919-26.
    • (2003) Cell Signal , vol.15 , Issue.10 , pp. 919-926
    • Kim, D.S.1    Hwang, E.S.2    Lee, J.E.3    Kim, S.Y.4    Park, K.C.5
  • 13
    • 52449092057 scopus 로고    scopus 로고
    • Targeting Sp hK1 as a new strategy against cancer
    • Shida, D., Takabe, K., Kapitonov, D. et al. Targeting Sp hK1 as a new strategy against cancer. Curr Drug Targets 2008, 9(8): 662-73.
    • (2008) Curr Drug Targets , vol.9 , Issue.8 , pp. 662-673
    • Shida, D.1    Takabe, K.2    Kapitonov, D.3
  • 14
    • 0034084510 scopus 로고    scopus 로고
    • Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells
    • Kim, W.H., Kang, K.H., Kim, M.Y. et al. Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells. Biochem Cell Biol 2000, 78(2): 127-35.
    • (2000) Biochem Cell Biol , vol.78 , Issue.2 , pp. 127-135
    • Kim, W.H.1    Kang, K.H.2    Kim, M.Y.3
  • 15
    • 0037203342 scopus 로고    scopus 로고
    • Ceramide in apoptosis: An overview and current perspectives
    • Pettus, B.J., Chalfant, C.E., Hannun, Y.A. Ceramide in apoptosis: An overview and current perspectives. Biochim Biophys Acta 2002, 1585(2-3): 114-25.
    • (2002) Biochim Biophys Acta , vol.1585 , Issue.2-3 , pp. 114-125
    • Pettus, B.J.1    Chalfant, C.E.2    Hannun, Y.A.3
  • 16
  • 17
    • 33746068256 scopus 로고    scopus 로고
    • NAD+/NADH and/or CoQ/CoQH2 ratios from plasma membrane electron transport may determine ceramide and sphingosine-1-phosphate levels accompanying G1 arrest and apoptosis
    • De Luca, T., Morre, D.M., Zhao, H. et al. NAD+/NADH and/or CoQ/CoQH2 ratios from plasma membrane electron transport may determine ceramide and sphingosine-1-phosphate levels accompanying G1 arrest and apoptosis. Biofactors 2005, 25(1-4): 43-60.
    • (2005) Biofactors , vol.25 , Issue.1-4 , pp. 43-60
    • De Luca, T.1    Morre, D.M.2    Zhao, H.3
  • 18
    • 55349130707 scopus 로고    scopus 로고
    • Phenoxodiol, a synthetic analog of genistein, generates ceramide and is equipotent in wild-type and multidrug-resistant human tumour cells
    • ASCO, May 13-17, Orlando, Abst 2075
    • Cabot, M.C., Yu, J.Y., Kelly, G.E. et al. Phenoxodiol, a synthetic analog of genistein, generates ceramide and is equipotent in wild-type and multidrug-resistant human tumour cells. 41st Annu Meet Am Soc Clin Oncol (ASCO) (May 13-17, Orlando) 2005, Abst 2075.
    • (2005) 41st Annu Meet Am Soc Clin Oncol
    • Cabot, M.C.1    Yu, J.Y.2    Kelly, G.E.3
  • 19
    • 33646426132 scopus 로고    scopus 로고
    • Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects
    • Gamble, J.R., Xia, P., Hahn, C.N. et al. Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects. Int J Cancer 2006, 118(10): 2412-20.
    • (2006) Int J Cancer , vol.118 , Issue.10 , pp. 2412-2420
    • Gamble, J.R.1    Xia, P.2    Hahn, C.N.3
  • 20
    • 34250339627 scopus 로고    scopus 로고
    • ECTO-NOX target for the anticancer isoflavone phenoxodiol
    • Morre, D.J., Chueh, P.J., Yagiz, K. et al. ECTO-NOX target for the anticancer isoflavone phenoxodiol. Oncol Res 2007, 16(7): 299-312.
    • (2007) Oncol Res , vol.16 , Issue.7 , pp. 299-312
    • Morre, D.J.1    Chueh, P.J.2    Yagiz, K.3
  • 21
    • 24644523642 scopus 로고    scopus 로고
    • Flavonoid compounds in maintenance of prostate health and prevention and treatment of cancer
    • Brown, D.M., Kelly, G.E., Husband, A.J. Flavonoid compounds in maintenance of prostate health and prevention and treatment of cancer. Mol Biotechnol 2005, 30(3): 253-70.
    • (2005) Mol Biotechnol , vol.30 , Issue.3 , pp. 253-270
    • Brown, D.M.1    Kelly, G.E.2    Husband, A.J.3
  • 22
    • 17144381683 scopus 로고    scopus 로고
    • Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1
    • Aguero, M.F., Facchinetti, M.M., Shelag, Z. et al. Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1. Cancer Res 2005, 65(8): 3364-73.
    • (2005) Cancer Res , vol.65 , Issue.8 , pp. 3364-3373
    • Aguero, M.F.1    Facchinetti, M.M.2    Shelag, Z.3
  • 23
    • 19944430097 scopus 로고    scopus 로고
    • Resistance of ovarian carcinoma cells to docetaxel is XIAP dependent and reversible by phenoxodiol
    • Sapi, E., Alvero, A.B., Chen, W. et al. Resistance of ovarian carcinoma cells to docetaxel is XIAP dependent and reversible by phenoxodiol. Oncol Res 2004, 14(11-12): 567-78.
    • (2004) Oncol Res , vol.14 , Issue.11-12 , pp. 567-578
    • Sapi, E.1    Alvero, A.B.2    Chen, W.3
  • 24
    • 34548254858 scopus 로고    scopus 로고
    • Phenoxodiol-topotecan coadministration exhibit significant anti-tumor activity without major adverse side effects
    • Alvaro, A.B., Brown, D., Montagna, M. et al. Phenoxodiol-topotecan coadministration exhibit significant anti-tumor activity without major adverse side effects. Cancer Biol Ther 2007, 6(4): 612-7.
    • (2007) Cancer Biol Ther , vol.6 , Issue.4 , pp. 612-617
    • Alvaro, A.B.1    Brown, D.2    Montagna, M.3
  • 25
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou, T.C., Talalay, P. Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 1984, 22: 27-55.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 26
    • 0030919715 scopus 로고    scopus 로고
    • Evaluation of synergism by a novel three-dimensional model for the combined action of cisplatin and etoposide on the growth of a human small-cell lung-cancer cell line, SBC-3
    • Kanzawa, F., Nishio, K., Fukuoka, K., Fukuda, M., Kunimoto, T., Saijo, N. Evaluation of synergism by a novel three-dimensional model for the combined action of cisplatin and etoposide on the growth of a human small-cell lung-cancer cell line, SBC-3. Int J Cancer 1997, 71(3): 311-9.
    • (1997) Int J Cancer , vol.71 , Issue.3 , pp. 311-319
    • Kanzawa, F.1    Nishio, K.2    Fukuoka, K.3    Fukuda, M.4    Kunimoto, T.5    Saijo, N.6
  • 27
    • 0036619301 scopus 로고    scopus 로고
    • Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: Possible involvement of the phosphoinositide-3 kinase/Akt pathway
    • Cheng, J.Q., Jiang, X., Fraser, M. et al. Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: Possible involvement of the phosphoinositide-3 kinase/Akt pathway. Drug Resist Updat 2002, 5(3-4): 131-46.
    • (2002) Drug Resist Updat , vol.5 , Issue.3-4 , pp. 131-146
    • Cheng, J.Q.1    Jiang, X.2    Fraser, M.3
  • 28
    • 0034104017 scopus 로고    scopus 로고
    • Apoptosis and chemoresistance in human ovarian cancer: Is Xiap a determinant?
    • Li, J., Sasaki, H., Sheng, Y.L. et al. Apoptosis and chemoresistance in human ovarian cancer: Is Xiap a determinant? Biol Signals Recept 2000, 9(2): 122-30.
    • (2000) Biol Signals Recept , vol.9 , Issue.2 , pp. 122-130
    • Li, J.1    Sasaki, H.2    Sheng, Y.L.3
  • 29
    • 0036463649 scopus 로고    scopus 로고
    • Apoptosis-based therapies
    • Reed, J.C. Apoptosis-based therapies. Nat Rev Drug Discov 2002, 1(2): 111-21.
    • (2002) Nat Rev Drug Discov , vol.1 , Issue.2 , pp. 111-121
    • Reed, J.C.1
  • 30
    • 0035266318 scopus 로고    scopus 로고
    • XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells
    • Asselin, E., Mills, G.B., Tsang, B.K. XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells. Cancer Res 2001, 61(5): 1862-8.
    • (2001) Cancer Res , vol.61 , Issue.5 , pp. 1862-1868
    • Asselin, E.1    Mills, G.B.2    Tsang, B.K.3
  • 31
    • 37849030454 scopus 로고    scopus 로고
    • Modulation of apoptosis to reverse chemoresistance
    • Mor, G., Montagna, M. K., Alvero, A.B. Modulation of apoptosis to reverse chemoresistance. Methods Mol Biol 2008, 414: 1-12.
    • (2008) Methods Mol Biol , vol.414 , pp. 1-12
    • Mor, G.1    Montagna, M.K.2    Alvero, A.B.3
  • 32
    • 0035955293 scopus 로고    scopus 로고
    • 3H]Dofetilide binding to HERG transfected membranes: A potential high throughput preclinical screen
    • Finlayson, K., Turnbull, L., January, C.T. et al. [3H]Dofetilide binding to HERG transfected membranes: A potential high throughput preclinical screen. Eur J Pharmacol 2001, 430(1): 147-8.
    • (2001) Eur J Pharmacol , vol.430 , Issue.1 , pp. 147-148
    • Finlayson, K.1    Turnbull, L.2    January, C.T.3
  • 33
    • 33646167077 scopus 로고    scopus 로고
    • Phase I trial of phenoxodiol delivered by continuous intravenous infusion in patients with solid cancer
    • Choueiri, T.K., Mekhail, T., Hutson, T.E. et al. Phase I trial of phenoxodiol delivered by continuous intravenous infusion in patients with solid cancer. Ann Oncol 2006, 17(5): 860-5.
    • (2006) Ann Oncol , vol.17 , Issue.5 , pp. 860-865
    • Choueiri, T.K.1    Mekhail, T.2    Hutson, T.E.3
  • 34
    • 0942287951 scopus 로고    scopus 로고
    • Long-term survival in a phase III, randomised study of topotecan versus paclitaxel in advanced epithelial ovarian carcinoma
    • ten Bokkel, H.W., Lane, S.R., Ross, G.A. Long-term survival in a phase III, randomised study of topotecan versus paclitaxel in advanced epithelial ovarian carcinoma. Ann Oncol 2004, 15(1): 100-3.
    • (2004) Ann Oncol , vol.15 , Issue.1 , pp. 100-103
    • ten Bokkel, H.W.1    Lane, S.R.2    Ross, G.A.3
  • 35
    • 0037631528 scopus 로고    scopus 로고
    • Weekly paclitaxel in patients with recurrent or persistent advanced ovarian cancer
    • Ghamande, S., Lele, S., Marchetti, D. et al. Weekly paclitaxel in patients with recurrent or persistent advanced ovarian cancer. Int J Gynecol Cancer 2003, 13(2): 142-7.
    • (2003) Int J Gynecol Cancer , vol.13 , Issue.2 , pp. 142-147
    • Ghamande, S.1    Lele, S.2    Marchetti, D.3


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