-
1
-
-
0029899783
-
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
-
Krummel MF, Allison JP. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J Exp Med 1996;183:2533-40.
-
(1996)
J Exp Med
, vol.183
, pp. 2533-2540
-
-
Krummel, M.F.1
Allison, J.P.2
-
2
-
-
0035102196
-
CTLA-4 regulates induction of anergy in vivo
-
Greenwald RJ, Boussiotis VA, Lorsbach RB, Abbas AK, Sharpe AH. CTLA-4 regulates induction of anergy in vivo. Immunity 2001;14:145-55.
-
(2001)
Immunity
, vol.14
, pp. 145-155
-
-
Greenwald, R.J.1
Boussiotis, V.A.2
Lorsbach, R.B.3
Abbas, A.K.4
Sharpe, A.H.5
-
3
-
-
0036301503
-
CTLA-4: New insights into its biological function and use in tumor immunotherapy
-
Egen JG, Kuhns MS, Allison JP. CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat Immunol 2002;3:611-8.
-
(2002)
Nat Immunol
, vol.3
, pp. 611-618
-
-
Egen, J.G.1
Kuhns, M.S.2
Allison, J.P.3
-
4
-
-
0032544067
-
CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
-
Hurwitz AA, Yu TF, Leach DR, Allison JP. CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma. Proc Natl Acad Sci U S A 1998;95:10067-71.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 10067-10071
-
-
Hurwitz, A.A.1
Yu, T.F.2
Leach, D.R.3
Allison, J.P.4
-
5
-
-
0033517152
-
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
-
van Elsas A, Hurwitz AA, Allison JP. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 1999;190:355-66.
-
(1999)
J Exp Med
, vol.190
, pp. 355-366
-
-
van Elsas, A.1
Hurwitz, A.A.2
Allison, J.P.3
-
6
-
-
17944364189
-
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy
-
van Elsas A, Sutmuller RP, Hurwitz AA, et al. Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy. J Exp Med 2001;194:481-9.
-
(2001)
J Exp Med
, vol.194
, pp. 481-489
-
-
van Elsas, A.1
Sutmuller, R.P.2
Hurwitz, A.A.3
-
7
-
-
0344341626
-
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
-
Hodi FS, Mihm MC, Soiffer RJ, et al. Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc Natl Acad Sci U S A 2003;100:4712-7.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4712-4717
-
-
Hodi, F.S.1
Mihm, M.C.2
Soiffer, R.J.3
-
8
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
Phan GQ, Yang JC, Sherry RM, et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci U S A 2003;100:8372-7.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
-
9
-
-
4344714990
-
Role of dendritic cell phenotype, determinant spreading, and negative costimulatory blockade in dendritic cell-based melanoma immunotherapy
-
Ribas A, Glaspy JA, Lee Y, et al. Role of dendritic cell phenotype, determinant spreading, and negative costimulatory blockade in dendritic cell-based melanoma immunotherapy. J Immunother 2004;27:354-67.
-
(2004)
J Immunother
, vol.27
, pp. 354-367
-
-
Ribas, A.1
Glaspy, J.A.2
Lee, Y.3
-
10
-
-
33744792341
-
Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
-
Beck KE, Blansfield JA, Tran KQ, et al. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J Clin Oncol 2006;24:2283-9.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2283-2289
-
-
Beck, K.E.1
Blansfield, J.A.2
Tran, K.Q.3
-
11
-
-
24944459890
-
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
-
Attia P, Phan GQ, Maker AV, et al. Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 2005;23:6043-53.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6043-6053
-
-
Attia, P.1
Phan, G.Q.2
Maker, A.V.3
-
12
-
-
20044395957
-
Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma
-
Sanderson K, Scotland R, Lee P, et al. Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma. J Clin Oncol 2005;23:741-50.
-
(2005)
J Clin Oncol
, vol.23
, pp. 741-750
-
-
Sanderson, K.1
Scotland, R.2
Lee, P.3
-
13
-
-
34250223096
-
A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer
-
Small EJ, Tchekmedyian NS, Rini BI, Fong L, Lowy I, Allison JP. A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer. Clin Cancer Res 2007;13:1810-5.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1810-1815
-
-
Small, E.J.1
Tchekmedyian, N.S.2
Rini, B.I.3
Fong, L.4
Lowy, I.5
Allison, J.P.6
-
14
-
-
0032809320
-
Therapy of advanced prostate cancer with granulocyte macrophage colony- stimulating factor
-
Small EJ, Reese DM, Um B, Whisenant S, Dixon SC, Figg WD. Therapy of advanced prostate cancer with granulocyte macrophage colony- stimulating factor. Clin Cancer Res 1999;5:1738-44.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1738-1744
-
-
Small, E.J.1
Reese, D.M.2
Um, B.3
Whisenant, S.4
Dixon, S.C.5
Figg, W.D.6
-
15
-
-
0037208522
-
Prostate-specific antigen kinetics as a measure of the biologic effect of granulocyte-macrophage colony-stimulating factor in patients with serologic progression of prostate cancer
-
Rini BI, Weinberg V, Bok R, Small EJ. Prostate-specific antigen kinetics as a measure of the biologic effect of granulocyte-macrophage colony-stimulating factor in patients with serologic progression of prostate cancer. J Clin Oncol 2003;21:99-105.
-
(2003)
J Clin Oncol
, vol.21
, pp. 99-105
-
-
Rini, B.I.1
Weinberg, V.2
Bok, R.3
Small, E.J.4
-
16
-
-
0032747375
-
Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: Recommendations from the Prostate-Specific Antigen Working Group
-
Bubley GJ, Carducci M, Dahut W, et al. Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group. J Clin Oncol 1999;17:3461-7.
-
(1999)
J Clin Oncol
, vol.17
, pp. 3461-3467
-
-
Bubley, G.J.1
Carducci, M.2
Dahut, W.3
-
17
-
-
34748846273
-
MAD-CT-2 identified as a novel melanoma cancer-testis antigen using phage immunoblot analysis
-
Dubovsky JA, Albertini MR, McNeel DG. MAD-CT-2 identified as a novel melanoma cancer-testis antigen using phage immunoblot analysis. J Immunother (1997) 2007;30:675-83.
-
(1997)
J Immunother
, vol.2007
, Issue.30
, pp. 675-683
-
-
Dubovsky, J.A.1
Albertini, M.R.2
McNeel, D.G.3
-
18
-
-
55949137090
-
Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma
-
Ribas A, Hauschild A, Kefford R, et al. Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma. J Clin Oncol 2008;26:9011.
-
(2008)
J Clin Oncol
, vol.26
, pp. 9011
-
-
Ribas, A.1
Hauschild, A.2
Kefford, R.3
-
19
-
-
28244492012
-
Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade
-
Maker AV, Attia P, Rosenberg SA. Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade. J Immunol 2005;175:7746-54.
-
(2005)
J Immunol
, vol.175
, pp. 7746-7754
-
-
Maker, A.V.1
Attia, P.2
Rosenberg, S.A.3
-
20
-
-
44949119433
-
Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma
-
Comin-Anduix B, Lee Y, Jalil J, et al. Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma. Journal of translational medicine 2008;6:22.
-
(2008)
Journal of translational medicine
, vol.6
, pp. 22
-
-
Comin-Anduix, B.1
Lee, Y.2
Jalil, J.3
-
22
-
-
33646349440
-
Clinical and immunological characteristics of patients with serologic progression of prostate cancer achieving long-term disease control with granulocyte-macrophage colony-stimulating factor
-
Rini BI, Fong L, Weinberg V, Kavanaugh B, Small EJ. Clinical and immunological characteristics of patients with serologic progression of prostate cancer achieving long-term disease control with granulocyte-macrophage colony-stimulating factor. J Urol 2006;175:2087-91.
-
(2006)
J Urol
, vol.175
, pp. 2087-2091
-
-
Rini, B.I.1
Fong, L.2
Weinberg, V.3
Kavanaugh, B.4
Small, E.J.5
-
23
-
-
45749104147
-
Granulocyte-macrophage colony-stimulating factor potentiates rituximab in patients with relapsed follicular lymphoma: Results of a phase II study
-
Cartron G, Zhao-Yang L, Baudard M, et al. Granulocyte-macrophage colony-stimulating factor potentiates rituximab in patients with relapsed follicular lymphoma: results of a phase II study. J Clin Oncol 2008;26:2725-31.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2725-2731
-
-
Cartron, G.1
Zhao-Yang, L.2
Baudard, M.3
-
24
-
-
25144483466
-
Autoantibody signatures in prostate cancer
-
Wang X, Yu J, Sreekumar A, et al. Autoantibody signatures in prostate cancer. N Engl J Med 2005;353:1224-35.
-
(2005)
N Engl J Med
, vol.353
, pp. 1224-1235
-
-
Wang, X.1
Yu, J.2
Sreekumar, A.3
-
25
-
-
12644276375
-
A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening
-
Chen YT, Scanlan MJ, Sahin U, et al. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc Natl Acad Sci U S A 1997;94:1914-8.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 1914-1918
-
-
Chen, Y.T.1
Scanlan, M.J.2
Sahin, U.3
-
26
-
-
3042687137
-
NY-ESO-1 mRNA expression and immunogenicity in advanced prostate cancer
-
Nakada T, Noguchi Y, Satoh S, et al. NY-ESO-1 mRNA expression and immunogenicity in advanced prostate cancer. Cancer Immun 2003;3:10.
-
(2003)
Cancer Immun
, vol.3
, pp. 10
-
-
Nakada, T.1
Noguchi, Y.2
Satoh, S.3
-
27
-
-
2442666480
-
NY-ESO-1 protein expression and humoral immune responses in prostate cancer
-
Fossa A, Berner A, Fossa SD, Hernes E, Gaudernack G, Smeland EB. NY-ESO-1 protein expression and humoral immune responses in prostate cancer. Prostate 2004;59:440-7.
-
(2004)
Prostate
, vol.59
, pp. 440-447
-
-
Fossa, A.1
Berner, A.2
Fossa, S.D.3
Hernes, E.4
Gaudernack, G.5
Smeland, E.B.6
-
28
-
-
57749108319
-
Clinical significance of p53 alterations in surgically treated prostate cancers
-
Schlomm T, Iwers L, Kirstein P, et al. Clinical significance of p53 alterations in surgically treated prostate cancers. Mod Pathol 2008;21:1371-8.
-
(2008)
Mod Pathol
, vol.21
, pp. 1371-1378
-
-
Schlomm, T.1
Iwers, L.2
Kirstein, P.3
-
29
-
-
33745125681
-
Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity
-
Jinushi M, Hodi FS, Dranoff G. Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity. Proc Natl Acad Sci U S A 2006;103:9190-5.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 9190-9195
-
-
Jinushi, M.1
Hodi, F.S.2
Dranoff, G.3
-
31
-
-
42149150398
-
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
-
Fasso M, Waitz R, Hou Y, et al. SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: a prostate tumor antigen identified by CTLA-4 blockade. Proc Natl Acad Sci U S A 2008;105:3509-14.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3509-3514
-
-
Fasso, M.1
Waitz, R.2
Hou, Y.3
|