메뉴 건너뛰기




Volumn 58, Issue 1, 2009, Pages 34-40

Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CLOSTRIDIUM DIFFICILE TOXIN A; INTERLEUKIN 8; MELANIN CONCENTRATING HORMONE; MELANIN CONCENTRATING HORMONE ANTIBODY; MELANIN CONCENTRATING HORMONE RECEPTOR 1; MELANIN CONCENTRATING HORMONE RECEPTOR 1 ANTIBODY; UNCLASSIFIED DRUG; BACTERIAL TOXIN; ENTEROTOXIN; HYPOPHYSIS HORMONE; HYPOTHALAMUS HORMONE; MCHR1 PROTEIN, HUMAN; MELANIN; MELANIN-CONCENTRATING HORMONE; MESSENGER RNA; SOMATOSTATIN RECEPTOR; TCDA PROTEIN, CLOSTRIDIUM DIFFICILE;

EID: 58249094056     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2008.155341     Document Type: Article
Times cited : (28)

References (56)
  • 1
    • 44149094314 scopus 로고    scopus 로고
    • Recent advances in Clostridium difficileassociated disease
    • Monaghan T, Boswell T, Mahida YR. Recent advances in Clostridium difficileassociated disease. Gut 2008; 57:850-0.
    • (2008) Gut , vol.57 , pp. 850-850
    • Monaghan, T.1    Boswell, T.2    Mahida, Y.R.3
  • 2
    • 45549098558 scopus 로고    scopus 로고
    • Bench-to-bedside review: Clostridium difficile colitis
    • Gould CV, McDonald LC. Bench-to-bedside review: Clostridium difficile colitis. Crit Care 2008; 12:203.
    • (2008) Crit Care , vol.12 , pp. 203
    • Gould, C.V.1    McDonald, L.C.2
  • 3
    • 33748563622 scopus 로고    scopus 로고
    • Emergence of Clostridium difficile-associated disease in North America and Europe
    • Kuijpar EJ, Coignard B, Tull P. Emergence of Clostridium difficile-associated disease in North America and Europe. Clin Microbiol Infect 2006; 126: 2-8.
    • (2006) Clin Microbiol Infect , vol.126 , pp. 2-8
    • Kuijpar, E.J.1    Coignard, B.2    Tull, P.3
  • 4
    • 0034999642 scopus 로고    scopus 로고
    • Microbes and microbial toxins: Paradigms for microbialmucosal interactions II. The integrated response of the intestine to Clostridium difficile toxins
    • Pothoulakis C, Lamont JT. Microbes and microbial toxins: paradigms for microbialmucosal interactions II. The integrated response of the intestine to Clostridium difficile toxins. Am J Physiol Gastrointest Liver Physiol 2001; 280:6178-3.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280 , pp. 6178-6183
    • Pothoulakis, C.1    Lamont, J.T.2
  • 5
    • 0035112067 scopus 로고    scopus 로고
    • Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins
    • Nusrat A, von Eichel-Streiber C, Turner JR, et al. Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins. Infect Immun 2001; 69:1329-6.
    • (2001) Infect Immun , vol.69 , pp. 1329-1336
    • Nusrat, A.1    von Eichel-Streiber, C.2    Turner, J.R.3
  • 6
    • 0032425435 scopus 로고    scopus 로고
    • Effect of Clostridium difficile toxin A on human colonic lamina propria cells: Early loss of macrophages followed by T-cell apoptosis
    • Mahida YR, Galvin A, Makh S, et al. Effect of Clostridium difficile toxin A on human colonic lamina propria cells: early loss of macrophages followed by T-cell apoptosis. Infect Immun 1998; 66:5462-.
    • (1998) Infect Immun , vol.66 , pp. 5462
    • Mahida, Y.R.1    Galvin, A.2    Makh, S.3
  • 7
    • 0029868433 scopus 로고    scopus 로고
    • Effect of Clostridium difficile toxin A on human intestinal epithelial cells: Induction of interleukin 8 production and apoptosis after cell detachment
    • Mahida YR, Makh S, Hyde S, et al. Effect of Clostridium difficile toxin A on human intestinal epithelial cells: induction of interleukin 8 production and apoptosis after cell detachment. Gut 1996; 38:337-7.
    • (1996) Gut , vol.38 , pp. 337-337
    • Mahida, Y.R.1    Makh, S.2    Hyde, S.3
  • 8
    • 34548472378 scopus 로고    scopus 로고
    • Inflammation and apoptosis in Clostridium difficile enteritis is mediated by PGE2 up-regulation of Fas ligand
    • Kim H, Rhee SH, Pothoulakis C, et al. Inflammation and apoptosis in Clostridium difficile enteritis is mediated by PGE2 up-regulation of Fas ligand. Gastroenterology 2007; 133:875-6.
    • (2007) Gastroenterology , vol.133 , pp. 875-876
    • Kim, H.1    Rhee, S.H.2    Pothoulakis, C.3
  • 9
    • 0029852142 scopus 로고    scopus 로고
    • Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum
    • Mantyh CR, Pappas TN, Lapp J A, et al. Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum. Gastroenterology 1996; 111:1272-0.
    • (1996) Gastroenterology , vol.111 , pp. 1272-1280
    • Mantyh, C.R.1    Pappas, T.N.2    Lapp, J.A.3
  • 10
    • 0031938938 scopus 로고    scopus 로고
    • CGRP upregulation in dorsal root ganglia and ileal mucosa during Clostridium difficile toxin A-induced enteritis
    • Keates AC, Castagliuolo L, Qiu B, et al. CGRP upregulation in dorsal root ganglia and ileal mucosa during Clostridium difficile toxin A-induced enteritis. Am J Physiol 1998; 274:G196-02.
    • (1998) Am J Physiol , vol.274
    • Keates, A.C.1    Castagliuolo, L.2    Qiu, B.3
  • 11
    • 0030896270 scopus 로고    scopus 로고
    • Castagliuolo l, Keates AC, Qiu B, et al. Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats. Proc Natl Acad Sci USA 1997; 94:4788-3.
    • Castagliuolo l, Keates AC, Qiu B, et al. Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats. Proc Natl Acad Sci USA 1997; 94:4788-3.
  • 12
    • 0034525733 scopus 로고    scopus 로고
    • Effects of Clostridium difficile toxins on epithelial cell barrier
    • Pothoulakis C. Effects of Clostridium difficile toxins on epithelial cell barrier. Ann NY Acad Sci 2000; 915:347-6.
    • (2000) Ann NY Acad Sci , vol.915 , pp. 347-356
    • Pothoulakis, C.1
  • 13
    • 0032523213 scopus 로고    scopus 로고
    • Castagliuolo l, Riegler M, Pasha A, et al. Neurokinin-1 (NK-1) receptor is required in Clostridium difficile-induced enteritis. J Clin Invest 1998; 101:1547-50.
    • Castagliuolo l, Riegler M, Pasha A, et al. Neurokinin-1 (NK-1) receptor is required in Clostridium difficile-induced enteritis. J Clin Invest 1998; 101:1547-50.
  • 14
    • 2942595862 scopus 로고    scopus 로고
    • Corticotropin- releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation
    • Anton PM, Gay J, Mykoniatis A, et al. Corticotropin- releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation. Proc Natl Acad Sci USA 2004; 101:8503-8.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8503-8508
    • Anton, P.M.1    Gay, J.2    Mykoniatis, A.3
  • 15
    • 33747762945 scopus 로고    scopus 로고
    • Corticotropin- releasing hormone receptor 2- deficient mice have reduced intestinal inflammatory responses
    • Kokkotou E, Torres D, Moss AC, et al. Corticotropin- releasing hormone receptor 2- deficient mice have reduced intestinal inflammatory responses. J Immunol 2006; 177:3355-61.
    • (2006) J Immunol , vol.177 , pp. 3355-3361
    • Kokkotou, E.1    Torres, D.2    Moss, A.C.3
  • 16
    • 0036327728 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone antagonists possess anti-inflammatory effects in the mouse ileum
    • Wlk M, Wang CC, Venihaki M, et al. Corticotropin-releasing hormone antagonists possess anti-inflammatory effects in the mouse ileum. Gastroenterology 2002; 123:505-15.
    • (2002) Gastroenterology , vol.123 , pp. 505-515
    • Wlk, M.1    Wang, C.C.2    Venihaki, M.3
  • 17
    • 0033559347 scopus 로고    scopus 로고
    • Neurotensin is a proinflammatory neuropeptide in colonic inflammation
    • Castagliuolo I, Wang CC, Valenick L, et al. Neurotensin is a proinflammatory neuropeptide in colonic inflammation. J Clin Invest 1999; 103:843-9.
    • (1999) J Clin Invest , vol.103 , pp. 843-849
    • Castagliuolo, I.1    Wang, C.C.2    Valenick, L.3
  • 18
    • 5144223713 scopus 로고    scopus 로고
    • Beyond skin color: Emerging roles of melanin-concentrating hormone in energy homeostasis and other physiological functions
    • Shi Y. Beyond skin color: emerging roles of melanin-concentrating hormone in energy homeostasis and other physiological functions. Peptides 2004; 25:1605-11.
    • (2004) Peptides , vol.25 , pp. 1605-1611
    • Shi, Y.1
  • 19
    • 5144223307 scopus 로고    scopus 로고
    • Expression and characterization of melanin-concentrating hormone receptors on mammalian cell lines
    • Eberle AN, Mild G, Schlumberger S. et al. Expression and characterization of melanin-concentrating hormone receptors on mammalian cell lines. Peptides 2004; 25:1585-95.
    • (2004) Peptides , vol.25 , pp. 1585-1595
    • Eberle, A.N.1    Mild, G.2    Schlumberger, S.3
  • 20
    • 0028904709 scopus 로고
    • Pro-melanin concentrating hormone messenger ribonucleic acid and peptides expression in peripheral tissues of the rat
    • Hervieu G, Nation JL. Pro-melanin concentrating hormone messenger ribonucleic acid and peptides expression in peripheral tissues of the rat. Neuroendocrinology 1995; 61:348-64.
    • (1995) Neuroendocrinology , vol.61 , pp. 348-364
    • Hervieu, G.1    Nation, J.L.2
  • 21
    • 0030066814 scopus 로고    scopus 로고
    • Similarities in cellular expression and functions of melanin-concentrating hormone and atrial natriuretic factor in the rat digestive tract
    • Hervieu G, Volant K, Grishina O, et al. Similarities in cellular expression and functions of melanin-concentrating hormone and atrial natriuretic factor in the rat digestive tract. Endocrinology 1996; 137:561-71.
    • (1996) Endocrinology , vol.137 , pp. 561-571
    • Hervieu, G.1    Volant, K.2    Grishina, O.3
  • 22
    • 0035100001 scopus 로고    scopus 로고
    • Melanin-concentrating hormone receptor is a target of leptin action in the mouse brain
    • Kokkotou EG, Tritos NA, Mastaitis JW, et al. Melanin-concentrating hormone receptor is a target of leptin action in the mouse brain. Endocrinology 2001; 142:680-6.
    • (2001) Endocrinology , vol.142 , pp. 680-686
    • Kokkotou, E.G.1    Tritos, N.A.2    Mastaitis, J.W.3
  • 23
    • 0037063325 scopus 로고    scopus 로고
    • Human immune cells express ppMCH mRNA and functional MCHR1 receptor
    • Veriaet M. Adamantidis A, Coumans B, et al. Human immune cells express ppMCH mRNA and functional MCHR1 receptor. FEBS Lett 2002; 527:205-10.
    • (2002) FEBS Lett , vol.527 , pp. 205-210
    • Veriaet, M.1    Adamantidis, A.2    Coumans, B.3
  • 24
    • 34547616863 scopus 로고    scopus 로고
    • Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone
    • Sandig H, McDonald J, Gilmour J, et al. Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone. Proc Natl Acad Sci USA 2007; 104:12440-4.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12440-12444
    • Sandig, H.1    McDonald, J.2    Gilmour, J.3
  • 25
    • 34547687431 scopus 로고    scopus 로고
    • Effect of ppMCH derived peptides on PBMC proliferation and cytokine expression
    • Coumans B, Grisar T, Nahon JL, et al. Effect of ppMCH derived peptides on PBMC proliferation and cytokine expression. Regul Pept 2007; 143:104-8.
    • (2007) Regul Pept , vol.143 , pp. 104-108
    • Coumans, B.1    Grisar, T.2    Nahon, J.L.3
  • 26
    • 0037371715 scopus 로고    scopus 로고
    • Leptin mediates Clostridium difficile toxin A- induced enteritis in mice
    • Mykoniatis A, Anton PM, Wlk M, et al. Leptin mediates Clostridium difficile toxin A- induced enteritis in mice. Gastroenterology 2003; 124:683-91.
    • (2003) Gastroenterology , vol.124 , pp. 683-691
    • Mykoniatis, A.1    Anton, P.M.2    Wlk, M.3
  • 27
    • 0035976975 scopus 로고    scopus 로고
    • Signal transduction pathways mediating neurotensin-stimulated interleukin-8 expression in human colonocytes
    • Zhao D, Keates AC, Kuhnt-Moore S, et al. Signal transduction pathways mediating neurotensin-stimulated interleukin-8 expression in human colonocytes. J Biol Chem 2001; 276:44464-71.
    • (2001) J Biol Chem , vol.276 , pp. 44464-44471
    • Zhao, D.1    Keates, A.C.2    Kuhnt-Moore, S.3
  • 28
    • 20444395071 scopus 로고    scopus 로고
    • Clostridium difficile toxin A regulates inducible C0X-2 and PGE2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAP kinase
    • Kim H, Rhee SH, Kokkotou E, et al. Clostridium difficile toxin A regulates inducible C0X-2 and PGE2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAP kinase. J Biol Chem 2005;280:21237-45.
    • (2005) J Biol Chem , vol.280 , pp. 21237-21245
    • Kim, H.1    Rhee, S.H.2    Kokkotou, E.3
  • 29
    • 21044453354 scopus 로고    scopus 로고
    • Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms
    • Kokkotou E, Jeon JY, Wang X, et al. Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms. Am J Physiol Regul Integr Comp Physiol 2005; 289:R117-24.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289
    • Kokkotou, E.1    Jeon, J.Y.2    Wang, X.3
  • 30
    • 0032576592 scopus 로고    scopus 로고
    • Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area
    • Bias CF, Saper CB, Maratos-Flier E, et al. Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. J Comp Neurol 1998; 402:442-59.
    • (1998) J Comp Neurol , vol.402 , pp. 442-459
    • Bias, C.F.1    Saper, C.B.2    Maratos-Flier, E.3
  • 31
    • 0035134670 scopus 로고    scopus 로고
    • Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance
    • Ludwig DS, Tritos NA, Mastaitis JW, et al. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest 2001; 107:379-86.
    • (2001) J Clin Invest , vol.107 , pp. 379-386
    • Ludwig, D.S.1    Tritos, N.A.2    Mastaitis, J.W.3
  • 32
    • 0043167963 scopus 로고    scopus 로고
    • Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine
    • Savidge TC, Pan WH, Newman P, et al. Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine. Gastroenterology 2003; 125:413-20.
    • (2003) Gastroenterology , vol.125 , pp. 413-420
    • Savidge, T.C.1    Pan, W.H.2    Newman, P.3
  • 33
    • 4644362730 scopus 로고    scopus 로고
    • Melanin-concentrating hormone receptor mutations and human obesity: Functional analysis
    • Gibson WT, Pissios P, Trombly DJ, et al. Melanin-concentrating hormone receptor mutations and human obesity: functional analysis. Obes Res 2004; 12:743-9.
    • (2004) Obes Res , vol.12 , pp. 743-749
    • Gibson, W.T.1    Pissios, P.2    Trombly, D.J.3
  • 34
    • 0042816504 scopus 로고    scopus 로고
    • Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways
    • Pissios P, Trombly DJ, Tzameli I, et al. Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways. Endocrinology 2003; 144:3514-23.
    • (2003) Endocrinology , vol.144 , pp. 3514-3523
    • Pissios, P.1    Trombly, D.J.2    Tzameli, I.3
  • 35
    • 0036901591 scopus 로고    scopus 로고
    • Substance P-stirnulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases
    • Zhao D, Kuhnt-Moore S, Zeng H, et al. Substance P-stirnulated interleukin-8 expression in human colonic epithelial cells involves Rho family small GTPases. Biochem J 2002; 368:665-72.
    • (2002) Biochem J , vol.368 , pp. 665-672
    • Zhao, D.1    Kuhnt-Moore, S.2    Zeng, H.3
  • 36
    • 33645684644 scopus 로고    scopus 로고
    • Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-kappaB pathway in human colonic epithelial cells
    • Zhao D, Zhan Y, Zeng H, et al. Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-kappaB pathway in human colonic epithelial cells. J Cell Biochem 2006; 97:1317-27.
    • (2006) J Cell Biochem , vol.97 , pp. 1317-1327
    • Zhao, D.1    Zhan, Y.2    Zeng, H.3
  • 37
    • 48749119360 scopus 로고    scopus 로고
    • Melanin-concentrating hormone as a mediator of intestinal inflammation
    • Kokkotou E, Moss AC, Torres D, et al. Melanin-concentrating hormone as a mediator of intestinal inflammation. Proc Natl Acad Sci USA 2008; 105:10613-8.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10613-10618
    • Kokkotou, E.1    Moss, A.C.2    Torres, D.3
  • 39
    • 33847030703 scopus 로고    scopus 로고
    • Melanin concentrating hormone is a novel regulator of islet function and growth
    • Pissios P, Ozcan U, Kokkotou E, et al. Melanin concentrating hormone is a novel regulator of islet function and growth. Diabetes 2007; 56:311-9.
    • (2007) Diabetes , vol.56 , pp. 311-319
    • Pissios, P.1    Ozcan, U.2    Kokkotou, E.3
  • 40
    • 0024428291 scopus 로고
    • Comparative study of Clostridium difficile toxin A and cholera toxin in rabbit ileum
    • Triadafilopoulos G, Pothoulakis C, Weiss R, et al. Comparative study of Clostridium difficile toxin A and cholera toxin in rabbit ileum. Gastroenterology 1989: 97:1186-92.
    • (1989) Gastroenterology , vol.97 , pp. 1186-1192
    • Triadafilopoulos, G.1    Pothoulakis, C.2    Weiss, R.3
  • 41
    • 0028316383 scopus 로고
    • Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit
    • Kolly CP. Becker S, Linevsky JK, et al. Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit. J Clin Invest 1994; 93:1257-65.
    • (1994) J Clin Invest , vol.93 , pp. 1257-1265
    • Kolly, C.P.1    Becker, S.2    Linevsky, J.K.3
  • 42
    • 0031968521 scopus 로고    scopus 로고
    • Melanin-concentrating hormone: A functional melanocortin antagonist in the hypothalamus
    • Ludwig DS, Mountjoy KG, Tatro JB, et al. Melanin-concentrating hormone: a functional melanocortin antagonist in the hypothalamus. Am J Physiol 1998; 274:E627-33.
    • (1998) Am J Physiol , vol.274
    • Ludwig, D.S.1    Mountjoy, K.G.2    Tatro, J.B.3
  • 43
    • 0028144458 scopus 로고
    • Central neurogenic antiinflammatory action of alpha-MSH: Modulation of peripheral inflammation induced by cytokines and other mediators of inflammation
    • Ceriani G, Macaluso A, Catania A, et al. Central neurogenic antiinflammatory action of alpha-MSH: modulation of peripheral inflammation induced by cytokines and other mediators of inflammation. Neuroendocrinology 1994; 59:138-43.
    • (1994) Neuroendocrinology , vol.59 , pp. 138-143
    • Ceriani, G.1    Macaluso, A.2    Catania, A.3
  • 44
    • 23944448890 scopus 로고    scopus 로고
    • Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves protein kinase Cdelta activation
    • Koon HW, Zhao D, Zhan Y, et al. Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves protein kinase Cdelta activation, J Pharmacol ExpTher 2005; 314:1393-400.
    • (2005) J Pharmacol ExpTher , vol.314 , pp. 1393-1400
    • Koon, H.W.1    Zhao, D.2    Zhan, Y.3
  • 45
    • 0033923004 scopus 로고    scopus 로고
    • Melanin-concentrating hormone regulates leptin synthesis and secretion in rat adipocytes
    • Bradley RL, Kokkotou EG, Maratos-Flier E, et al. Melanin-concentrating hormone regulates leptin synthesis and secretion in rat adipocytes. Diabetes 2000; 49:1073-7.
    • (2000) Diabetes , vol.49 , pp. 1073-1077
    • Bradley, R.L.1    Kokkotou, E.G.2    Maratos-Flier, E.3
  • 46
    • 0034525477 scopus 로고    scopus 로고
    • The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways
    • Hawes BE, Kil E, Green B, et al. The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways Endocrinology 2000; 141:4524-32.
    • (2000) Endocrinology , vol.141 , pp. 4524-4532
    • Hawes, B.E.1    Kil, E.2    Green, B.3
  • 47
    • 21744453992 scopus 로고    scopus 로고
    • Neurotensin stimulates interleukin-8 expression through modulation of l kappa B alpha phosphorylation and p65 transcriptional activity: Involvement of protein kinase C alpha
    • Zhao D, Zhan Y, Zeng H, et al. Neurotensin stimulates interleukin-8 expression through modulation of l kappa B alpha phosphorylation and p65 transcriptional activity: involvement of protein kinase C alpha. Mol Pharmacol 2005; 67:2025-31.
    • (2005) Mol Pharmacol , vol.67 , pp. 2025-2031
    • Zhao, D.1    Zhan, Y.2    Zeng, H.3
  • 48
    • 0031027020 scopus 로고    scopus 로고
    • The melanin-concentrating hormone gene in human: Flanking region analysis, fine chromosome mapping, and tissue-specific expression
    • Viale A, Zhixing Y, Breton C, et al. The melanin-concentrating hormone gene in human: flanking region analysis, fine chromosome mapping, and tissue-specific expression. Brain Res Mol Brain Res 1997; 46:243-55.
    • (1997) Brain Res Mol Brain Res , vol.46 , pp. 243-255
    • Viale, A.1    Zhixing, Y.2    Breton, C.3
  • 49
    • 0026669447 scopus 로고
    • Hydrolysis of rat melanin-concentrating hormone by endopeptidase 24.11 (neutral endopeptidase)
    • Checler F, Dauch P, Barelli H, et al. Hydrolysis of rat melanin-concentrating hormone by endopeptidase 24.11 (neutral endopeptidase). Biochem J 1992; 286:217-21.
    • (1992) Biochem J , vol.286 , pp. 217-221
    • Checler, F.1    Dauch, P.2    Barelli, H.3
  • 50
    • 0027167752 scopus 로고    scopus 로고
    • Hwang L, Leichter R, Okamoto A, et al. Downregulation of neutral endopeptidase IEC 3.4.24.111 in the inflamed rat intestine. Am J Physiol 1993; 264:G735-43.
    • Hwang L, Leichter R, Okamoto A, et al. Downregulation of neutral endopeptidase IEC 3.4.24.111 in the inflamed rat intestine. Am J Physiol 1993; 264:G735-43.
  • 51
    • 0034889163 scopus 로고    scopus 로고
    • Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A
    • Mrkwood KS, Bunnett NW, Maa J, et al. Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A. Am J Physiol Gastrointest Liver Physiol 2001; 281:G544-51.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281
    • Mrkwood, K.S.1    Bunnett, N.W.2    Maa, J.3
  • 52
    • 13044264447 scopus 로고    scopus 로고
    • Sturiale S, Barbara G, Qiu B, et al. Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P. Proc Natl Acad Sci USA 1999; 96:11653-8.
    • Sturiale S, Barbara G, Qiu B, et al. Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P. Proc Natl Acad Sci USA 1999; 96:11653-8.
  • 53
    • 0036080142 scopus 로고    scopus 로고
    • Leptin: A pivotal mediator of intestinal inflammation in mice
    • Siegmund B, Lehr HA, Fantuzzi G. Leptin: a pivotal mediator of intestinal inflammation in mice. Gastroenterology 2002; 122:2011-25.
    • (2002) Gastroenterology , vol.122 , pp. 2011-2025
    • Siegmund, B.1    Lehr, H.A.2    Fantuzzi, G.3
  • 54
    • 33847065560 scopus 로고    scopus 로고
    • Adiponectin deficiency protects mice from chemically induced colonic inflammation
    • Fayad R, Pini M, Sennello JA, et al. Adiponectin deficiency protects mice from chemically induced colonic inflammation. Gastroenterology 2007; 132:601-14.
    • (2007) Gastroenterology , vol.132 , pp. 601-614
    • Fayad, R.1    Pini, M.2    Sennello, J.A.3
  • 55
    • 0034731566 scopus 로고    scopus 로고
    • Modulation of the fish immune system by hormones
    • Harris J, Bird DJ. Modulation of the fish immune system by hormones. Vet Immunol Immunopathol 2000;77:163-76.
    • (2000) Vet Immunol Immunopathol , vol.77 , pp. 163-176
    • Harris, J.1    Bird, D.J.2
  • 56
    • 5444226515 scopus 로고    scopus 로고
    • Melanin-concentrating hormone signaling systems in fish
    • Kawauchi H, Baker Bl. Melanin-concentrating hormone signaling systems in fish. Peptides 2004; 25:1577-84.
    • (2004) Peptides , vol.25 , pp. 1577-1584
    • Kawauchi, H.1    Baker, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.