Achieving synaptically relevant pulses of neurotransmitter using PDMS microfluidics

Journal of Neuroscience Methods

Volumn 177, Issue 2, 2009, Pages 294-302

  Botzolakis, E J ^a   Maheshwari, A ^b   Feng, H J ^b   Lagrange, A H ^b   Shaver, J H ^a,b   Kassebaum, N J ^c   Venkataraman, R ^c   Baudenbacher, F ^c   Macdonald, R L ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

Cys loop; Electrophysiology; GABAA receptor; Ion channel; Kinetics; Ligand gated; Patch clamp; Pharmacology; Photolithography; Solution exchange; Solution switching

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; CYSTEINE; DIMETICONE; ION CHANNEL; LIGAND; LIGAND GATED ION CHANNEL; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; MEMBRANE CURRENT; MICROFLUIDICS; MUTATION; NERVE CONDUCTION; NEUROTRANSMITTER RELEASE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; REPRODUCIBILITY; SYNAPTIC TRANSMISSION;

ALLOSTERIC REGULATION; CELL LINE; DRUG DELIVERY SYSTEMS; ELECTRONICS, MEDICAL; ELECTROPHYSIOLOGY; HUMANS; INHIBITORY POSTSYNAPTIC POTENTIALS; MICROFLUIDIC ANALYTICAL TECHNIQUES; NEURAL INHIBITION; NEUROCHEMISTRY; NEUROTRANSMITTER AGENTS; PATCH-CLAMP TECHNIQUES; PRESYNAPTIC TERMINALS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; SYNAPTIC TRANSMISSION; TIME FACTORS;

EID: 58149527845     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2008.10.014     Document Type: Article

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