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Volumn 13, Issue 8, 2008, Pages 1097-1113

Broad advances in understanding HIV resistance to antiretrovirals: Report on the XVII International HIV Drug Resistance Workshop

Author keywords

[No Author keywords available]

Indexed keywords

3' AZIDO 2',3' DIDEOXYGUANOSINE; ANTIRETROVIRUS AGENT; BEVIRIMAT; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; CMX 157; DARUNAVIR; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ETRAVIRINE; HEXADECYLOXYPROPYL TENOFOVIR; HUMAN IMMUNODEFICIENCY VIRUS 1 CORECEPTOR; IDX 899; INTEGRASE INHIBITOR; LAMIVUDINE; LAMIVUDINE PLUS ZIDOVUDINE; LOPINAVIR PLUS RITONAVIR; MONOCLONAL ANTIBODY; NEVIRAPINE; PLACEBO; PROTEINASE INHIBITOR; RALTEGRAVIR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; ROAB 3952; STAVUDINE; TENOFOVIR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VICRIVIROC; VIRUS RECEPTOR; ZIDOVUDINE;

EID: 58149522617     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (6)

References (59)
  • 1
    • 52749088638 scopus 로고    scopus 로고
    • Loss of raltegravir susceptibility in treated patients is conferred by multiple non-overlapping genetic pathways
    • Fransen S, Gupta S, Danovich R, et al. Loss of raltegravir susceptibility in treated patients is conferred by multiple non-overlapping genetic pathways. Antivir Ther 2008; 13 Suppl 3:A9.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Fransen, S.1    Gupta, S.2    Danovich, R.3
  • 2
    • 52749085595 scopus 로고    scopus 로고
    • Longitudinal analysis of resistance to the HIV-1 integrase inhibitor raltegravir: Results from P005, a phase II study in treatment-experienced patients
    • Miller MD, Danovich RM, Ke Y, et al. Longitudinal analysis of resistance to the HIV-1 integrase inhibitor raltegravir: results from P005, a phase II study in treatment-experienced patients. Antivir Ther 2008; 13 Suppl 3:A8.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Miller, M.D.1    Danovich, R.M.2    Ke, Y.3
  • 3
    • 52749083694 scopus 로고    scopus 로고
    • Virological and immunological outcomes in a cohort of patients failing integrase inhibitors
    • Hatano H, Lampiris H, Huang W, et al. Virological and immunological outcomes in a cohort of patients failing integrase inhibitors. Antivir Ther 2008; 13 Suppl 3:A12.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Hatano, H.1    Lampiris, H.2    Huang, W.3
  • 4
    • 37249065868 scopus 로고    scopus 로고
    • Resistance to the HIV-integrase inhibitor raltegravir: Analysis of protocol 005, a Phase II study in patients with triple-class resistant HIV-1 infection
    • Hazuda DJ, Miller MD, Nguyen BY, Zhao J. Resistance to the HIV-integrase inhibitor raltegravir: analysis of protocol 005, a Phase II study in patients with triple-class resistant HIV-1 infection. Antivir Ther 2007; 12:S10.
    • (2007) Antivir Ther , vol.12
    • Hazuda, D.J.1    Miller, M.D.2    Nguyen, B.Y.3    Zhao, J.4
  • 5
    • 3242769788 scopus 로고    scopus 로고
    • Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques
    • Hazuda DJ, Young SD, Guare JP, et al. Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques. Science 2004; 305:528-532.
    • (2004) Science , vol.305 , pp. 528-532
    • Hazuda, D.J.1    Young, S.D.2    Guare, J.P.3
  • 6
    • 34948888180 scopus 로고    scopus 로고
    • Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3′,3′-dimethylsuccinyl) betulinic acid (bevirimat) against human immunodeficiency virus infection
    • Smith PF, Ogundele A, Forrest A, et al. Phase I and II study of the safety, virologic effect, and pharmacokinetics/pharmacodynamics of single-dose 3-o-(3′,3′-dimethylsuccinyl) betulinic acid (bevirimat) against human immunodeficiency virus infection. Antimicrob Agents Chemother 2007; 51:3574-3581.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3574-3581
    • Smith, P.F.1    Ogundele, A.2    Forrest, A.3
  • 7
    • 58149481128 scopus 로고    scopus 로고
    • HIV-1 gag polymorphisms determine treatment response to bevirimat (PA-457)
    • McCallister S, Lalezari J, Richmond G, et al. HIV-1 gag polymorphisms determine treatment response to bevirimat (PA-457). Antivir Ther 2008; 13 Suppl 3:A10.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • McCallister, S.1    Lalezari, J.2    Richmond, G.3
  • 8
    • 58149519978 scopus 로고    scopus 로고
    • HIV-1 susceptibility to the maturation inhibitor bevirimat is modulated by natural polymorphisms at positions 369-371 in Gag spacer peptide 1
    • Van Baelen K, Salzwedel K, De Wolf H, et al. HIV-1 susceptibility to the maturation inhibitor bevirimat is modulated by natural polymorphisms at positions 369-371 in Gag spacer peptide 1. Antivir Ther 2008; 13 Suppl 3:A30.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Van Baelen, K.1    Salzwedel, K.2    De Wolf, H.3
  • 9
    • 58149509960 scopus 로고    scopus 로고
    • Novel resistance profile of the potent nucleoside analogue reverse transcriptase inhibitor 3′-azido-2′,3′-dideoxyguanosine
    • Meteer J, Koontz D, Rapp KL, et al. Novel resistance profile of the potent nucleoside analogue reverse transcriptase inhibitor 3′-azido-2′,3′-dideoxyguanosine. Antivir Ther 2008; 13 Suppl 3:A5.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Meteer, J.1    Koontz, D.2    Rapp, K.L.3
  • 10
    • 35748933494 scopus 로고    scopus 로고
    • Update of the drug resistance mutations in HIV-1: 2007
    • Johnson VA, Brun-Vezinet F, Clotet B, et al. Update of the drug resistance mutations in HIV-1: 2007. Top HIV Med 2007; 15:119-125.
    • (2007) Top HIV Med , vol.15 , pp. 119-125
    • Johnson, V.A.1    Brun-Vezinet, F.2    Clotet, B.3
  • 11
    • 58149511895 scopus 로고    scopus 로고
    • Hexadecyloxypropyl tenofovir (CMX157) has enhanced potency in vitro against NRTI-resistant HIV relative to tenofovir and a favorable preclinical profile
    • Lanier ER, Lampert B, Trost I, et al. Hexadecyloxypropyl tenofovir (CMX157) has enhanced potency in vitro against NRTI-resistant HIV relative to tenofovir and a favorable preclinical profile. Antivir Ther 2008; 13 Suppl 3:A6.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Lanier, E.R.1    Lampert, B.2    Trost, I.3
  • 12
    • 85069300788 scopus 로고    scopus 로고
    • In vitro cross-resistance profile, antiviral activity, safety and pharmacokinetics in HIV-1 infected patients of IDX899, a novel HIV-1 NNRTI with high barrier to resistance
    • Murphy R, Zata C, Jakubik JJ, et al. In vitro cross-resistance profile, antiviral activity, safety and pharmacokinetics in HIV-1 infected patients of IDX899, a novel HIV-1 NNRTI with high barrier to resistance. Antivir Ther 2008; 13 Suppl 3:A7.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Murphy, R.1    Zata, C.2    Jakubik, J.J.3
  • 13
    • 58149479199 scopus 로고    scopus 로고
    • Antiviral activity, safety and pharmacokinetics of IDX899, a novel HIV-1 non-nucleoside reverse transcriptase inhibitor with high barrier to resistance, in treatment-naive HIV-1-infected patients
    • Murphy R, Zala C, Zhou XJ, et al. Antiviral activity, safety and pharmacokinetics of IDX899, a novel HIV-1 non-nucleoside reverse transcriptase inhibitor with high barrier to resistance, in treatment-naive HIV-1-infected patients. Antivir Ther 2008; 13 Suppl 3:A27.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Murphy, R.1    Zala, C.2    Zhou, X.J.3
  • 14
    • 58149495936 scopus 로고    scopus 로고
    • de Bethune MP, Andries K, Azijn H, et al. TMC278, a new potent NNRTI, with an increased barrier to resistance and favourable pharmacokinetic profile. 12th Conference on Retroviruses and Opportunistic Infections. February 22-25, 2005. Boston. Poster 556.
    • de Bethune MP, Andries K, Azijn H, et al. TMC278, a new potent NNRTI, with an increased barrier to resistance and favourable pharmacokinetic profile. 12th Conference on Retroviruses and Opportunistic Infections. February 22-25, 2005. Boston. Poster 556.
  • 15
    • 85069301682 scopus 로고    scopus 로고
    • Potent HIV-1 inhibitors with a reserve of binding energy against resistance mutations
    • Welch BD, Redman JP, Paul S, et al. Potent HIV-1 inhibitors with a reserve of binding energy against resistance mutations. Antivir Ther 2008; 13 Suppl 3:A3.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Welch, B.D.1    Redman, J.P.2    Paul, S.3
  • 16
    • 58149498170 scopus 로고    scopus 로고
    • Resistance to CCR5mAb RoAb3952 is associated with a shift in binding from the extracellular domain 2 to the N terminus of CCR5
    • Jekle A, Chhabra M, Chou E, et al. Resistance to CCR5mAb RoAb3952 is associated with a shift in binding from the extracellular domain 2 to the N terminus of CCR5. Antivir Ther 2009; 13 Suppl 3:A4.
    • (2009) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Jekle, A.1    Chhabra, M.2    Chou, E.3
  • 17
    • 33947406436 scopus 로고    scopus 로고
    • Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities
    • Ji C, Brandt M, Dioszegi M, et al. Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities. Antiviral Res 2007; 74:125-137.
    • (2007) Antiviral Res , vol.74 , pp. 125-137
    • Ji, C.1    Brandt, M.2    Dioszegi, M.3
  • 18
    • 85069299313 scopus 로고    scopus 로고
    • Low frequency K103N mutations are strongly associated with inadequate virological responses to non-nucleoside reverse transcriptase inhibitor based therapy
    • Hunt G, Coovadia A, Abrams JE, et al. Low frequency K103N mutations are strongly associated with inadequate virological responses to non-nucleoside reverse transcriptase inhibitor based therapy. Antivir Ther 2008; 13 Suppl 3:A132.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Hunt, G.1    Coovadia, A.2    Abrams, J.E.3
  • 19
    • 33847034809 scopus 로고    scopus 로고
    • Persistence of K103N-containing HIV-1 variants after single-dose nevirapine for prevention of HIV-1 mother-to-child transmission
    • Flys TS, Donnell D, Mwatha A, et al. Persistence of K103N-containing HIV-1 variants after single-dose nevirapine for prevention of HIV-1 mother-to-child transmission. J Infect Dis 2007; 195:711-715.
    • (2007) J Infect Dis , vol.195 , pp. 711-715
    • Flys, T.S.1    Donnell, D.2    Mwatha, A.3
  • 20
    • 33846156885 scopus 로고    scopus 로고
    • Response to antiretroviral therapy after a single, peripartum dose of nevirapine
    • Lockman S, Shapiro RL, Smeaton LM, et al. Response to antiretroviral therapy after a single, peripartum dose of nevirapine. N Engl J Med 2007; 356:135-147.
    • (2007) N Engl J Med , vol.356 , pp. 135-147
    • Lockman, S.1    Shapiro, R.L.2    Smeaton, L.M.3
  • 21
    • 63349101361 scopus 로고    scopus 로고
    • Determination of phenotypic clinical cut-offs for etravirine: Pooled week 24 results of the DUET-1 and DUET-2 trial
    • Peeters M, Nijs S, Vingerhoets J, et al. Determination of phenotypic clinical cut-offs for etravirine: pooled week 24 results of the DUET-1 and DUET-2 trial. Antivir Ther 2008; 13 Suppl 3:A133.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Peeters, M.1    Nijs, S.2    Vingerhoets, J.3
  • 22
    • 58149515307 scopus 로고    scopus 로고
    • Biological and clinical cut-off analyses for etravirine in the PhenoSense HIV assay
    • Coakley E, Chappey C, Benhamida J, et al. Biological and clinical cut-off analyses for etravirine in the PhenoSense HIV assay. Antivir Ther 2008; 13 Suppl 3:A134.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Coakley, E.1    Chappey, C.2    Benhamida, J.3
  • 23
    • 34347327010 scopus 로고    scopus 로고
    • Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial
    • Madruga JV, Cahn P, Grinsztejn B, et al. Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial. Lancet 2007; 370:29-38.
    • (2007) Lancet , vol.370 , pp. 29-38
    • Madruga, J.V.1    Cahn, P.2    Grinsztejn, B.3
  • 24
    • 34347354196 scopus 로고    scopus 로고
    • Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial
    • Lazzarin A, Campbell T, Clotet B, et al. Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial. Lancet 2007; 370:39-48.
    • (2007) Lancet , vol.370 , pp. 39-48
    • Lazzarin, A.1    Campbell, T.2    Clotet, B.3
  • 25
    • 58149505548 scopus 로고    scopus 로고
    • HIV-1 genotype algorithms for prediction of etravirine susceptibility: Novel mutations and weighting factors identified through correlations to phenotype
    • Benhamida J, Chappey C, Coakley E, Parkin NT. HIV-1 genotype algorithms for prediction of etravirine susceptibility: novel mutations and weighting factors identified through correlations to phenotype. Antivir Ther 2008; 13 Suppl 3:A142.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Benhamida, J.1    Chappey, C.2    Coakley, E.3    Parkin, N.T.4
  • 26
    • 58149498169 scopus 로고    scopus 로고
    • Increased phenotypic susceptibility to etravirine in HIV-1 with nucleoside reverse transcriptase inhibitor resistance
    • Benhamida J, Coakley E, Parkin NT, Chappey C. Increased phenotypic susceptibility to etravirine in HIV-1 with nucleoside reverse transcriptase inhibitor resistance. Antivir Ther 2008; 13 Suppl 3:A24.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Benhamida, J.1    Coakley, E.2    Parkin, N.T.3    Chappey, C.4
  • 27
    • 85069299968 scopus 로고    scopus 로고
    • Emergence of drug resistance after failure of first-line HAART is associated with intensity of virological monitoring: A systematic analysis of cohort and trial data specifically addressing the WHO public health approach to antiretroviral therapy
    • Gupta RK, Hill A, Sawyer AW, et al. Emergence of drug resistance after failure of first-line HAART is associated with intensity of virological monitoring: a systematic analysis of cohort and trial data specifically addressing the WHO public health approach to antiretroviral therapy. Antivir Ther 2008; 13 Suppl 3:A131.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Gupta, R.K.1    Hill, A.2    Sawyer, A.W.3
  • 29
    • 58149530505 scopus 로고    scopus 로고
    • Change in regional prevalence, clade and epidemiology of HIV-1 drug resistance mutations and clade among antiviral therapy-naive patients in the United States from 2000 to 2007
    • Ross LL, Dix I, Wine B, et al. Change in regional prevalence, clade and epidemiology of HIV-1 drug resistance mutations and clade among antiviral therapy-naive patients in the United States from 2000 to 2007. Antivir Ther 2008; 13 Suppl 3:A160.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Ross, L.L.1    Dix, I.2    Wine, B.3
  • 31
    • 85069301041 scopus 로고    scopus 로고
    • the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the IeDEA. The prevalence of multidrug resistance among treated patients in North America and its impact on mortality
    • Deeks SG, the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the IeDEA. The prevalence of multidrug resistance among treated patients in North America and its impact on mortality. Antivir Ther 2008; 13 Suppl 3:A153.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Deeks, S.G.1
  • 32
    • 33749021387 scopus 로고    scopus 로고
    • Emergence of drug resistance is associated with an increased risk of death among patients first starting HAART
    • Hogg RS, Bangsberg DR, Lima VD, et al. Emergence of drug resistance is associated with an increased risk of death among patients first starting HAART. PLoS Med 2006; 3:e356.
    • (2006) PLoS Med , vol.3
    • Hogg, R.S.1    Bangsberg, D.R.2    Lima, V.D.3
  • 33
    • 58149530501 scopus 로고    scopus 로고
    • Injection drug users have a higher probability of developing resistance than non-injection drug users regardless of adherence or initial treatment regimen
    • Gill VS, Lima VD, Fernandes KA, Harrigan PR. Injection drug users have a higher probability of developing resistance than non-injection drug users regardless of adherence or initial treatment regimen. Antivir Ther 2008; 13 Suppl 3:A157.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Gill, V.S.1    Lima, V.D.2    Fernandes, K.A.3    Harrigan, P.R.4
  • 34
    • 19944431012 scopus 로고    scopus 로고
    • Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy
    • Harrigan PR, Hogg RS, Dong WWY, et al. Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy. J Infect Dis 2005; 191:339-347.
    • (2005) J Infect Dis , vol.191 , pp. 339-347
    • Harrigan, P.R.1    Hogg, R.S.2    Dong, W.W.Y.3
  • 35
    • 55049137395 scopus 로고    scopus 로고
    • Dynamic HIV-1 escape from vicriviroc therapy in vivo
    • Tsibris AMN, Arnaout R, Korber B, et al. Dynamic HIV-1 escape from vicriviroc therapy in vivo. Antivir Ther 2008; 13 Suppl 3:A97.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Tsibris, A.M.N.1    Arnaout, R.2    Korber, B.3
  • 36
    • 34347379935 scopus 로고    scopus 로고
    • Phase II study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211
    • Gulick RM, Su Z, Flexner C, et al. Phase II study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211. J Infect Dis 2007; 196:304-312.
    • (2007) J Infect Dis , vol.196 , pp. 304-312
    • Gulick, R.M.1    Su, Z.2    Flexner, C.3
  • 37
    • 55049102344 scopus 로고    scopus 로고
    • Response to vicriviroc in HIV-infected, treatment-experienced individuals using an enhanced version of the Trofile HIV co-receptor tropism assay [Trofile (ES)]: Reanalysis of ACTG 5211 results
    • Su Z, Reeves JD, Krambrink A, et al. Response to vicriviroc in HIV-infected, treatment-experienced individuals using an enhanced version of the Trofile HIV co-receptor tropism assay [Trofile (ES)]: reanalysis of ACTG 5211 results. Antivir Ther 2008; 13 Suppl 3:A98.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Su, Z.1    Reeves, J.D.2    Krambrink, A.3
  • 38
    • 34548261959 scopus 로고    scopus 로고
    • Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
    • Low AJ, Dong W, Chan D, et al. Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates. AIDS 2007; 21:F17-F24.
    • (2007) AIDS , vol.21
    • Low, A.J.1    Dong, W.2    Chan, D.3
  • 39
    • 55049125807 scopus 로고    scopus 로고
    • Improved detection of X4 virus by V3 genotyping: Application to plasma RNA and proviral DNA
    • Moores A, Thielen A, Dong W, et al. Improved detection of X4 virus by V3 genotyping: application to plasma RNA and proviral DNA. Antivir Ther 2008; 13 Suppl 3:A99.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Moores, A.1    Thielen, A.2    Dong, W.3
  • 40
    • 58149500107 scopus 로고    scopus 로고
    • Improved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation
    • Thielen A, Harrigan PR, Lou AJ, et al. Improved genotypic prediction of HIV-1 coreceptor usage by incorporating V2 loop sequence variation. Antivir Ther 2008; 13 Suppl 3:A100.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Thielen, A.1    Harrigan, P.R.2    Lou, A.J.3
  • 41
    • 55049126129 scopus 로고    scopus 로고
    • Inferring viral tropism from genotype with massively parallel sequencing: Qualitative and quantitative analysis
    • Däumer MP, Kaiser R, Klein R, et al. Inferring viral tropism from genotype with massively parallel sequencing: qualitative and quantitative analysis. Antivir Ther 2008; 13 Suppl 3:A101.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Däumer, M.P.1    Kaiser, R.2    Klein, R.3
  • 42
    • 58149481130 scopus 로고    scopus 로고
    • Intensification with efavirenz or lopinavir/ritonavir does not reduce residual HIV-1 viraemia in patients on standard antiretroviral therapy
    • Maldarelli F, Wiegand A, Palmer S, et al. Intensification with efavirenz or lopinavir/ritonavir does not reduce residual HIV-1 viraemia in patients on standard antiretroviral therapy. Antivir Ther 2008; 13 Suppl 3:A79.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Maldarelli, F.1    Wiegand, A.2    Palmer, S.3
  • 43
    • 0141676556 scopus 로고    scopus 로고
    • Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years
    • Havlir DV, Strain MC, Clerici M, et al. Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years. J Virol 2003; 77:11212-11219.
    • (2003) J Virol , vol.77 , pp. 11212-11219
    • Havlir, D.V.1    Strain, M.C.2    Clerici, M.3
  • 44
    • 34247584237 scopus 로고    scopus 로고
    • ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia
    • Maldarelli F, Palmer S, King MS, et al. ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia. PLoS Pathog 2007; 3:e46.
    • (2007) PLoS Pathog , vol.3
    • Maldarelli, F.1    Palmer, S.2    King, M.S.3
  • 45
    • 85069301125 scopus 로고    scopus 로고
    • The selection, transmission and persistence of drug-resistant HIV-1 in infants prophylaxed with single-dose nevirapine varies by timing of infection
    • Micek MA, Blanco AJ, Beck IA, et al. The selection, transmission and persistence of drug-resistant HIV-1 in infants prophylaxed with single-dose nevirapine varies by timing of infection. Antivir Ther 2008; 13 Suppl 3:A78.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Micek, M.A.1    Blanco, A.J.2    Beck, I.A.3
  • 46
    • 85069300698 scopus 로고    scopus 로고
    • Correlations between transmitted HIV-1 drug resistance mutations and the human leukocyte antigen alleles of therapy-naive HIV patients
    • Schweitzer F, Mueller SM, Daeumer M, et al. Correlations between transmitted HIV-1 drug resistance mutations and the human leukocyte antigen alleles of therapy-naive HIV patients. Antivir Ther 2008; 13 Suppl 3:A76.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Schweitzer, F.1    Mueller, S.M.2    Daeumer, M.3
  • 47
    • 85069300619 scopus 로고    scopus 로고
    • HIV-1 recombination in patients infected with multiple HIV-1 variants from the same donor
    • Kearney M, Shao W, Maldarelli F, et al. HIV-1 recombination in patients infected with multiple HIV-1 variants from the same donor. Antivir Ther 2008; 13 Suppl 3:A77.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Kearney, M.1    Shao, W.2    Maldarelli, F.3
  • 48
    • 85069300290 scopus 로고    scopus 로고
    • Single cell analysis of HIV DNA from infected patients
    • Palmer S, Maldarelli F, Kearney M, et al. Single cell analysis of HIV DNA from infected patients. Antivir Ther 2008; 13 Suppl 3:A75.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Palmer, S.1    Maldarelli, F.2    Kearney, M.3
  • 49
    • 58149530463 scopus 로고    scopus 로고
    • Mechanism by which the HIV integrase active-site mutation N155H confers resistance to raltegravir
    • Grobler JA, Stillmock KA, Miller MD, Hazuda DJ. Mechanism by which the HIV integrase active-site mutation N155H confers resistance to raltegravir. Antivir Ther 2008; 13 Suppl 3:A41.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Grobler, J.A.1    Stillmock, K.A.2    Miller, M.D.3    Hazuda, D.J.4
  • 50
    • 85069301359 scopus 로고    scopus 로고
    • Structural basis for K65R function: Tenofovir resistance, reduced nucleotide incorporate and excision antagonism
    • Das K, Bandwar R, White KL, et al. Structural basis for K65R function: tenofovir resistance, reduced nucleotide incorporate and excision antagonism. Antivir Ther 2008; 13 Suppl 3:A44.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Das, K.1    Bandwar, R.2    White, K.L.3
  • 51
    • 33846063300 scopus 로고    scopus 로고
    • Mutations in the connection domain of HIV-1 reverse transcriptase increase 3′-azido-3′-deoxythymidine resistance
    • Nikolenko GN, Delviks-Frankenberry KA, Palmer S, et al. Mutations in the connection domain of HIV-1 reverse transcriptase increase 3′-azido-3′-deoxythymidine resistance. Proc Natl Acad Sci U S A 2007; 104:317-322.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 317-322
    • Nikolenko, G.N.1    Delviks-Frankenberry, K.A.2    Palmer, S.3
  • 52
    • 85069300079 scopus 로고    scopus 로고
    • Zidovudine resistance related connection mutations in HIV-1 reverse transcriptase cause selective dissociation from RNase II competent complexes
    • Beilhartz GL, Ehteshami M, Scarth B, et al. Zidovudine resistance related connection mutations in HIV-1 reverse transcriptase cause selective dissociation from RNase II competent complexes. Antivir Ther 2008; 13 Suppl 3:A45.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Beilhartz, G.L.1    Ehteshami, M.2    Scarth, B.3
  • 53
    • 34547105526 scopus 로고    scopus 로고
    • Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3′-azido-3′-dideoxythymidine
    • Brehm JH, Koontz D, Meteer JD, et al. Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3′-azido-3′-dideoxythymidine. J Virol 2007; 81:7852-7859.
    • (2007) J Virol , vol.81 , pp. 7852-7859
    • Brehm, J.H.1    Koontz, D.2    Meteer, J.D.3
  • 54
    • 85069300353 scopus 로고    scopus 로고
    • Q509L in HIV-1 reverse transcriptase increases zidovudine resistance by promoting polymerase-competent versus RNase H-competent binding on RNA/DNA template/primers with short duplex lengths
    • Brehm J, Mellors J, Sluis-Cremer N. Q509L in HIV-1 reverse transcriptase increases zidovudine resistance by promoting polymerase-competent versus RNase H-competent binding on RNA/DNA template/primers with short duplex lengths. Antivir Ther 2008; 13 Suppl 3:A46.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Brehm, J.1    Mellors, J.2    Sluis-Cremer, N.3
  • 55
    • 58149530462 scopus 로고    scopus 로고
    • Evolution of reverse transcriptase connection domain mutations in patients on antiretroviral therapy
    • von Wyl V, Bürgisser P, Yerly S, et al. Evolution of reverse transcriptase connection domain mutations in patients on antiretroviral therapy. Antivir Ther 2008; 13 Suppl 3:A47.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • von Wyl, V.1    Bürgisser, P.2    Yerly, S.3
  • 56
    • 85069301019 scopus 로고    scopus 로고
    • Structural explanations to altered drug resistance pathways in HIV-1 non-clade B proteases
    • Bandaranayake RM, Ng C, Kolli M, et al. Structural explanations to altered drug resistance pathways in HIV-1 non-clade B proteases. Antivir Ther 2008; 13 Suppl 3:A42.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Bandaranayake, R.M.1    Ng, C.2    Kolli, M.3
  • 57
    • 58149483323 scopus 로고    scopus 로고
    • How hepatitis C virus NS3-4A protease R155K/T strains can discriminate VX-950 and ITMN-191 but affect differentially SCH-503034
    • Courcambeck J, Bouzidi M, Roche G, et al. How hepatitis C virus NS3-4A protease R155K/T strains can discriminate VX-950 and ITMN-191 but affect differentially SCH-503034. Antivir Ther 2008; 13 Suppl 3:A43.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Courcambeck, J.1    Bouzidi, M.2    Roche, G.3
  • 58
    • 34250722018 scopus 로고    scopus 로고
    • The HBV drug entecavir - effects on HIV-1 replication and resistance
    • McMahon MA, Jilek BL, Brennan TP, et al. The HBV drug entecavir - effects on HIV-1 replication and resistance. N Engl J Med 2007; 356:2614-2621.
    • (2007) N Engl J Med , vol.356 , pp. 2614-2621
    • McMahon, M.A.1    Jilek, B.L.2    Brennan, T.P.3
  • 59
    • 85069300078 scopus 로고    scopus 로고
    • Delayed chain-termination protects the hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase
    • Tchesnokov E, Obikhod A, Schinazi RF, Götte M. Delayed chain-termination protects the hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase. Antivir Ther 2008; 13 Suppl 3:A48.
    • (2008) Antivir Ther , vol.13 , Issue.SUPPL. 3
    • Tchesnokov, E.1    Obikhod, A.2    Schinazi, R.F.3    Götte, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.