메뉴 건너뛰기




Volumn 55, Issue 4, 2008, Pages 749-752

Identification of 2-[2-nitro-4-(trifluoromethyl)benzoyl]-cyclohexane-1,3-dione metabolites in urine of patients suffering from tyrosinemia type I with the use of 1H and 19F NMR spectroscopy

Author keywords

NMR; NTBC metabolites; Tyrosinemia

Indexed keywords


EID: 58149502714     PISSN: 0001527X     EISSN: 1734154X     Source Type: Journal    
DOI: 10.18388/abp.2008_3036     Document Type: Article
Times cited : (10)

References (15)
  • 1
    • 2542568185 scopus 로고    scopus 로고
    • Structure of the ferrous form of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis in complex with the therapeutic herbicide, NTBC
    • Brownlee JM, Johnson-Winters K, Harrison DHT, Moran GR (2004) Structure of the ferrous form of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis in complex with the therapeutic herbicide, NTBC. Biochemistry 43: 6370-6377.
    • (2004) Biochemistry , vol.43 , pp. 6370-6377
    • Brownlee, J.M.1    Johnson-Winters, K.2    Harrison, D.H.T.3    Moran, G.R.4
  • 3
    • 0031871486 scopus 로고    scopus 로고
    • Tyrosinaemia type I and NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione)
    • Holme E, Lindstedt S (1998) Tyrosinaemia type I and NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione). J Inherit Metab Dis 21: 507-517.
    • (1998) J Inherit Metab Dis , vol.21 , pp. 507-517
    • Holme, E.1    Lindstedt, S.2
  • 4
    • 0042825545 scopus 로고    scopus 로고
    • Interaction of (4-hydroxyphenyl)pyruvate dioxygenase with the specific inhibitor 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione
    • Kavana M, Moran GR (2003) Interaction of (4-hydroxyphenyl)pyruvate dioxygenase with the specific inhibitor 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione. Biochemistry 42: 10238-10245.
    • (2003) Biochemistry , vol.42 , pp. 10238-10245
    • Kavana, M.1    Moran, G.R.2
  • 5
    • 0026675589 scopus 로고
    • Treatment of hereditary tyrosinemia type 1 by inhibition of 4-hydroxyphenylpyruvate dioxygenase
    • Linstedt S, Holme E (1992) Treatment of hereditary tyrosinemia type 1 by inhibition of 4-hydroxyphenylpyruvate dioxygenase. Lancet 340: 813-817.
    • (1992) Lancet , vol.340 , pp. 813-817
    • Linstedt, S.1    Holme, E.2
  • 6
    • 7344229198 scopus 로고    scopus 로고
    • From toxicological problem to therapeutic use: The discovery of the mode action of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC), its toxicology and development as a drug
    • Lock EA, Ellis MK, Gaskin P, Robinson M, Auton TR, Provan WM, Smith LL, Prisbylla MP, Mutter LC, Lee DL (1998) From toxicological problem to therapeutic use: The discovery of the mode action of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC), its toxicology and development as a drug. J Inherit Metab Dis 21: 498-506.
    • (1998) J Inherit Metab Dis , vol.21 , pp. 498-506
    • Lock, E.A.1    Ellis, M.K.2    Gaskin, P.3    Robinson, M.4    Auton, T.R.5    Provan, W.M.6    Smith, L.L.7    Prisbylla, M.P.8    Mutter, L.C.9    Lee, D.L.10
  • 8
    • 0030062842 scopus 로고    scopus 로고
    • The cyanide catalyzed isomerisation of enol esters derived from cyclic 1,3-diketones
    • Montes NA, Burger U (1996) The cyanide catalyzed isomerisation of enol esters derived from cyclic 1,3-diketones. Tetrahedron Lett 37: 1007-1010.
    • (1996) Tetrahedron Lett , vol.37 , pp. 1007-1010
    • Montes, N.A.1    Burger, U.2
  • 9
    • 27544447429 scopus 로고    scopus 로고
    • Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl)pyruvate dioxygenase: Active site contributions to drug inhibition
    • Neidig ML, Decker A, Kavana M, Moran GR, Solomon EI (2005) Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl)pyruvate dioxygenase: Active site contributions to drug inhibition. Biochem Biophys Res Commun 338: 206-214.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 206-214
    • Neidig, M.L.1    Decker, A.2    Kavana, M.3    Moran, G.R.4    Solomon, E.I.5
  • 10
    • 0029984561 scopus 로고    scopus 로고
    • Treatment of two children with hereditary tyrosinaemia type I and long-standing renal disease with a 4-hydroxyphenylpyruvate dioxygenase inhibitor (NTBC)
    • Pronicka E, Rowińska E, Zawadzki J, Holme E, Linstedt S (1996) Treatment of two children with hereditary tyrosinaemia type I and long-standing renal disease with a 4-hydroxyphenylpyruvate dioxygenase inhibitor (NTBC). J Inherit Metab Dis 19: 234-238.
    • (1996) J Inherit Metab Dis , vol.19 , pp. 234-238
    • Pronicka, E.1    Rowińska, E.2    Zawadzki, J.3    Holme, E.4    Linstedt, S.5
  • 12
    • 0028313670 scopus 로고
    • Inhibition of barnyardgrass 4-hydroxyphenylpyruvate dioxygenase by sulcotrione
    • Secor J (1994) Inhibition of barnyardgrass 4-hydroxyphenylpyruvate dioxygenase by sulcotrione. Plant Physiol 106: 1429-1433.
    • (1994) Plant Physiol , vol.106 , pp. 1429-1433
    • Secor, J.1
  • 13
    • 33744930105 scopus 로고    scopus 로고
    • 13C NMR, and computational DFT studies of the structure of 2-acylcyclohexane-1,3-diones and their alkali metal salts In solution
    • 13C NMR, and computational DFT studies of the structure of 2-acylcyclohexane-1,3-diones and their alkali metal salts In solution. J Org Chem 71: 4636-4641.
    • (2007) J Org Chem , vol.71 , pp. 4636-4641
    • Szczeciński, P.1    Gryff-Keller, A.2    Molchanov, S.3
  • 14
    • 0028243026 scopus 로고
    • Synthesis of 2-acyl-4-hydroxycyclohexane-1,3-diones, Kairomones and defensive compounds of some insects
    • Zaitsev VG, Polozov GI, Lakhvich FA (1994) Synthesis of 2-acyl-4-hydroxycyclohexane-1,3-diones, Kairomones and defensive compounds of some insects. Tetrahedron 50: 6377-6386.
    • (1994) Tetrahedron , vol.50 , pp. 6377-6386
    • Zaitsev, V.G.1    Polozov, G.I.2    Lakhvich, F.A.3
  • 15
    • 0034099967 scopus 로고    scopus 로고
    • Synthesis of the rac-6-hydroxy-3-methoxycyclohex-2-enone and resolution through recrystallization of its diastereomeric N-tosyl-(S)-proline esters
    • Zaitsev VG, Sachava DG, Yankovskaya GS, Garbuz NI (2000) Synthesis of the rac-6-hydroxy-3-methoxycyclohex-2-enone and resolution through recrystallization of its diastereomeric N-tosyl-(S)-proline esters. Chirality 12: 287-290.
    • (2000) Chirality , vol.12 , pp. 287-290
    • Zaitsev, V.G.1    Sachava, D.G.2    Yankovskaya, G.S.3    Garbuz, N.I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.