메뉴 건너뛰기




Volumn 6, Issue SUPPL. 1, 2008, Pages 208-213

Treatment of iron overload in thalassemia

Author keywords

Anemia, iron overload; Deferasirox; Deferiprone; Desfernoxamine; Iron chelation therapy; Thalassemia

Indexed keywords

CREATININE; DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; DEFEROXAMINE MESYLATE; IRON CHELATING AGENT;

EID: 58149479414     PISSN: 15654753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (28)

References (45)
  • 1
    • 58149490682 scopus 로고    scopus 로고
    • Guidelines for the clinical management of thalassaemia. 2007 (cited 2008 June 8); 2nd Edition: Available from: http://www.thalassaemia.org.cy/ MyData/Books/Guidelines%20to%20the%20Clinical%20Management%20of%20 Thalassaemia.PDF
    • Guidelines for the clinical management of thalassaemia. 2007 (cited 2008 June 8); 2nd Edition: (Available from: http://www.thalassaemia.org.cy/ MyData/Books/Guidelines%20to%20the%20Clinical%20Management%20of%20 Thalassaemia.PDF
  • 3
    • 34047214190 scopus 로고    scopus 로고
    • Optimal management strategies for chronic iron overload
    • Barton JC. Optimal management strategies for chronic iron overload. Drugs 2007;67:685-700
    • (2007) Drugs , vol.67 , pp. 685-700
    • Barton, J.C.1
  • 4
    • 0035725868 scopus 로고    scopus 로고
    • Practical management of iron overload
    • Porter JB. Practical management of iron overload. Br J Haematol 2001;115:239-252
    • (2001) Br J Haematol , vol.115 , pp. 239-252
    • Porter, J.B.1
  • 5
    • 0022111669 scopus 로고
    • Heart cells in culture: A model of myocardial iron overload and chelation
    • Link G, Pinson A, Hershko C. Heart cells in culture: a model of myocardial iron overload and chelation. J Lab Clin Med 1985;106:147-153
    • (1985) J Lab Clin Med , vol.106 , pp. 147-153
    • Link, G.1    Pinson, A.2    Hershko, C.3
  • 11
    • 38349157810 scopus 로고    scopus 로고
    • Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major
    • Cohen AR, Glimm E, Porter JB. Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major. Blood 2008;5;111:583-587
    • (2008) Blood , vol.5 , Issue.111 , pp. 583-587
    • Cohen, A.R.1    Glimm, E.2    Porter, J.B.3
  • 14
    • 0025186342 scopus 로고
    • High incidence of cardiomyopathy in beta-thalassaemia patients receiving regular transfusion and iron chelation: Reversal by intensified chelation
    • Aldouri MA, Wonke B, Hoffbrand AV, Flynn DM, Ward SE, Agnew JE, Hilson AJ. High incidence of cardiomyopathy in beta-thalassaemia patients receiving regular transfusion and iron chelation: reversal by intensified chelation. Acta Haematol 1990;84:113-117
    • (1990) Acta Haematol , vol.84 , pp. 113-117
    • Aldouri, M.A.1    Wonke, B.2    Hoffbrand, A.V.3    Flynn, D.M.4    Ward, S.E.5    Agnew, J.E.6    Hilson, A.J.7
  • 15
    • 0034651775 scopus 로고    scopus 로고
    • Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intravenous catheters in high-risk beta-thalassemia
    • Davis BA, Porter JB. Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intravenous catheters in high-risk beta-thalassemia. Blood 2000;15;95:1229-1236
    • (2000) Blood , vol.15 , Issue.95 , pp. 1229-1236
    • Davis, B.A.1    Porter, J.B.2
  • 16
    • 0030048681 scopus 로고    scopus 로고
    • Results of long-term iron-chelating therapy
    • Gabutti V, Piga A. Results of long-term iron-chelating therapy. Acta Haematol 1996;95:26-36
    • (1996) Acta Haematol , vol.95 , pp. 26-36
    • Gabutti, V.1    Piga, A.2
  • 17
    • 0034631379 scopus 로고    scopus 로고
    • Survival in beta-thalassaemia major in the UK: Data from the UK Thalassaemia Register
    • Modell B, Khan M, Darlison M. Survival in beta-thalassaemia major in the UK: data from the UK Thalassaemia Register. Lancet 2000;10;355:2051-2052
    • (2000) Lancet , vol.10 , Issue.355 , pp. 2051-2052
    • Modell, B.1    Khan, M.2    Darlison, M.3
  • 18
    • 0032887235 scopus 로고    scopus 로고
    • Deferiprone: A review of its clinical potential in iron overload in beta-thalassemia major and other transfusion-dependent diseases
    • Barman Balfour JA, Foster RH. Deferiprone: a review of its clinical potential in iron overload in beta-thalassemia major and other transfusion-dependent diseases. Drugs 1999;58:553-578
    • (1999) Drugs , vol.58 , pp. 553-578
    • Barman Balfour, J.A.1    Foster, R.H.2
  • 19
    • 0037630378 scopus 로고    scopus 로고
    • Role of deferiprone in chelation therapy for transfusional iron overload
    • Hoffbrand AV, Cohen A, Hershko C. Role of deferiprone in chelation therapy for transfusional iron overload. Blood 2003;1;102:17-24
    • (2003) Blood , vol.1 , Issue.102 , pp. 17-24
    • Hoffbrand, A.V.1    Cohen, A.2    Hershko, C.3
  • 21
    • 0042943205 scopus 로고    scopus 로고
    • Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone
    • Cohen AR, Galanello R, Piga A, De Sanctis V, Tricta F. Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone. Blood 2003;1;102:1583-1587
    • (2003) Blood , vol.1 , Issue.102 , pp. 1583-1587
    • Cohen, A.R.1    Galanello, R.2    Piga, A.3    De Sanctis, V.4    Tricta, F.5
  • 23
    • 0037125595 scopus 로고    scopus 로고
    • Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
    • Anderson LJ, Wonke B, Prescott E, Holden S, Walker JM, Pennell DJ. Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet 2002;17;360:516-520
    • (2002) Lancet , vol.17 , Issue.360 , pp. 516-520
    • Anderson, L.J.1    Wonke, B.2    Prescott, E.3    Holden, S.4    Walker, J.M.5    Pennell, D.J.6
  • 25
    • 0031784438 scopus 로고    scopus 로고
    • Combined therapy with deferiprone and desferrioxamine
    • Wonke B, Wright C, Hoffbrand AV. Combined therapy with deferiprone and desferrioxamine. Br J Haematol 1998;103:361-364
    • (1998) Br J Haematol , vol.103 , pp. 361-364
    • Wonke, B.1    Wright, C.2    Hoffbrand, A.V.3
  • 26
    • 0347363715 scopus 로고    scopus 로고
    • Combined therapy with desferrioxamine and deferiprone in thalassemic patients: Effect on urinary iron excretion
    • Kattamis A, Kassou C, Berdousi H, Ladis V, Papassotiriou I, Kattamis C. Combined therapy with desferrioxamine and deferiprone in thalassemic patients: effect on urinary iron excretion. Haematologica 2003;88:1423-1425
    • (2003) Haematologica , vol.88 , pp. 1423-1425
    • Kattamis, A.1    Kassou, C.2    Berdousi, H.3    Ladis, V.4    Papassotiriou, I.5    Kattamis, C.6
  • 27
    • 34247103036 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance
    • Tanner MA, Galanello R, Dessi C, Smith GC, Westwood MA, Agus A, Roughton M, Assomull R, Nair SV, Walker JM, Pennell DJ. A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance. Circulation 2007;10;115:1876-1884
    • (2007) Circulation , vol.10 , Issue.115 , pp. 1876-1884
    • Tanner, M.A.1    Galanello, R.2    Dessi, C.3    Smith, G.C.4    Westwood, M.A.5    Agus, A.6    Roughton, M.7    Assomull, R.8    Nair, S.V.9    Walker, J.M.10    Pennell, D.J.11
  • 29
    • 33847245863 scopus 로고    scopus 로고
    • Effects of combined deferiprone and desferrioxamine iron chelating therapy in beta-thalassemia major end-stage heart failure: A case report
    • Porcu M, Landis N, Salis S, Corda M, Orru P, Serra E, Usai B, Matta G, Galanello R. Effects of combined deferiprone and desferrioxamine iron chelating therapy in beta-thalassemia major end-stage heart failure: a case report. Eur J Heart Fail 2007;9:320-322
    • (2007) Eur J Heart Fail , vol.9 , pp. 320-322
    • Porcu, M.1    Landis, N.2    Salis, S.3    Corda, M.4    Orru, P.5    Serra, E.6    Usai, B.7    Matta, G.8    Galanello, R.9
  • 30
  • 31
    • 58149501052 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals. Deferasirox (Exjade®): Summary of product characteristics. 2008 (cited 2008 9 Jun); Available from: http://www.emea.europa.eu/humandocs/PDFs/EPAR/exjade/H-670-Pl-en.pdf
    • Novartis Pharmaceuticals. Deferasirox (Exjade®): Summary of product characteristics. 2008 (cited 2008 9 Jun); Available from: http://www.emea.europa.eu/humandocs/PDFs/EPAR/exjade/H-670-Pl-en.pdf
  • 33
    • 58149486595 scopus 로고    scopus 로고
    • FDA approves first oral drug for chronic iron overload. 2005 (cited 2007 April 1); Available from: http://www.fda.gov/bbs/topics/news/2005/ NEW01258.html
    • FDA approves first oral drug for chronic iron overload. 2005 (cited 2007 April 1); Available from: http://www.fda.gov/bbs/topics/news/2005/ NEW01258.html
  • 37
    • 58149491880 scopus 로고    scopus 로고
    • Cappellini MD, Vichinsky E, Galanello R, Piga A, Williamson P, Porter JB. Long-Term Treatment with Deferasirox (Exjade®, ICL670), a Once-Daily Oral Iron Chelator, Is Effective in Patients with Transfusion-Dependent Anemias. ASH Annual Meeting Abstracts. Blood 2007;110:2777
    • Cappellini MD, Vichinsky E, Galanello R, Piga A, Williamson P, Porter JB. Long-Term Treatment with Deferasirox (Exjade®, ICL670), a Once-Daily Oral Iron Chelator, Is Effective in Patients with Transfusion-Dependent Anemias. ASH Annual Meeting Abstracts. Blood 2007;110:2777
  • 38
    • 58149501572 scopus 로고    scopus 로고
    • Piga A, Vichinsky E, Forni GL, Kilinc Y, Maseruka H, Kattamis A. Long-Term Efficacy and Safety with Deferasirox (Exjade®, ICL670), a Once-Daily Oral Iron Chelator, in Pediatric Patients. ASH Annual Meeting Abstracts. Blood 2007;110:2774
    • Piga A, Vichinsky E, Forni GL, Kilinc Y, Maseruka H, Kattamis A. Long-Term Efficacy and Safety with Deferasirox (Exjade®, ICL670), a Once-Daily Oral Iron Chelator, in Pediatric Patients. ASH Annual Meeting Abstracts. Blood 2007;110:2774
  • 39
    • 58149525734 scopus 로고    scopus 로고
    • Porter JB, Cohen AR, Ford JM, Cappellini MD. Impact of Dose Adjustments on Serum Ferritin (SF) Levels during Long-Term Treatment with Once-Daily, Oral Deferasirox (Exjade®, ICL670). ASH Annual Meeting Abstracts. Blood 2007;110:2778
    • Porter JB, Cohen AR, Ford JM, Cappellini MD. Impact of Dose Adjustments on Serum Ferritin (SF) Levels during Long-Term Treatment with Once-Daily, Oral Deferasirox (Exjade®, ICL670). ASH Annual Meeting Abstracts. Blood 2007;110:2778
  • 40
    • 27644539382 scopus 로고    scopus 로고
    • Intracellular labile iron pools as direct targets of iron chelators: A fluorescence study of chelator action in living cells
    • Glickstein H, El RB, Shvartsman M, Cabantchik ZI. Intracellular labile iron pools as direct targets of iron chelators: a fluorescence study of chelator action in living cells. Blood 2005;1;106:3242-3250
    • (2005) Blood , vol.1 , Issue.106 , pp. 3242-3250
    • Glickstein, H.1    El, R.B.2    Shvartsman, M.3    Cabantchik, Z.I.4
  • 42
    • 34248566563 scopus 로고    scopus 로고
    • Response of myocardial T2 to oral deferasirox monotherapy for 1 year in 29 patients with transfusion-dependent anaemias; a subgroup analysis (abstract)
    • Eleftheriou P, Tanner M, Pennell D, Porter J. Response of myocardial T2 to oral deferasirox monotherapy for 1 year in 29 patients with transfusion-dependent anaemias; a subgroup analysis (abstract). Haematologica 2006;91(Suppl 1):999
    • (2006) Haematologica , vol.91 , Issue.SUPPL. 1 , pp. 999
    • Eleftheriou, P.1    Tanner, M.2    Pennell, D.3    Porter, J.4
  • 43
    • 58149501570 scopus 로고    scopus 로고
    • Wood J, Thompson AA, Paley C, Kang B, Giardina P, Harmatz P, Virkus J, Coates T. Exjade® Reduces Cardiac Iron Burden in Chronically Transfused β-Thalassemia Patients: An MRI T2 Study. ASH Annual Meeting Abstracts. Blood 2007;110:2781
    • Wood J, Thompson AA, Paley C, Kang B, Giardina P, Harmatz P, Virkus J, Coates T. Exjade® Reduces Cardiac Iron Burden in Chronically Transfused β-Thalassemia Patients: An MRI T2 Study. ASH Annual Meeting Abstracts. Blood 2007;110:2781
  • 44
    • 58149514315 scopus 로고    scopus 로고
    • Daar S, Taher A, Pathare A, Nick H, Krahn U and Hadler D. Sustained Protection from Labile Plasma Iron (LPI) with the Once-Daily, Oral Iron Chelator Deferasirox (Exjade®, ICL670) in Iron-Overloaded β-Thalassemia Patients. ASH Annual Meeting Abstracts. Blood 2006;108:1773
    • Daar S, Taher A, Pathare A, Nick H, Krahn U and Hadler D. Sustained Protection from Labile Plasma Iron (LPI) with the Once-Daily, Oral Iron Chelator Deferasirox (Exjade®, ICL670) in Iron-Overloaded β-Thalassemia Patients. ASH Annual Meeting Abstracts. Blood 2006;108:1773
  • 45
    • 42949148046 scopus 로고    scopus 로고
    • Clinical application of deferasirox: Practical patient management
    • Vichinsky E. Clinical application of deferasirox: practical patient management. Am J Hematol 2008;83:398-402
    • (2008) Am J Hematol , vol.83 , pp. 398-402
    • Vichinsky, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.