Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte

International Immunopharmacology

Volumn 9, Issue 1, 2009, Pages 97-102

  Kadoshima Yamaoka, Kumiko ^a   Murakawa, Masao ^a   Goto, Megumi ^a   Tanaka, Yoshitaka ^a   Inoue, Hidekazu ^a   Murafuji, Hidenobu ^a   Hayashi, Yasuhiro ^a   Nagahira, Kazuhiro ^a   Miura, Kenju ^a   Nakatsuka, Takashi ^a   Chamoto, Kenji ^b   Fukuda, Yoshiaki ^a   Nishimura, Takashi ^b  

^a DAIICHI SANKYO CO   (Japan)

^b Institute for Genetic Medicine   (Japan)

Author keywords

cAMP; Cytotoxic T lymphocytes (CTL); Mixed lymphocyte reaction (MLR); Phosphodiesterase 7 (PDE7)

Indexed keywords

1 CYCLOHEXYL N [6 (4 HYDROXY 1 PIPERIDINYL) 3 PYRIDINYL] 3 METHYL 1H THIENO[2,3 C]PYRAZOLE 5 CARBOXAMIDE; ASB 16165; BUCLADESINE; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CYCLIC AMP; FORSKOLIN; PHOSPHODIESTERASE VII INHIBITOR; ROLIPRAM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOIMMUNE DISEASE; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIVISION; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; LYMPHOCYTE FUNCTION; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; SPLEEN LYMPHOCYTE;

ANIMALS; BUCLADESINE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CELL LINE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 7; FEMALE; FLOW CYTOMETRY; FORSKOLIN; IMMUNOSUPPRESSIVE AGENTS; INDICATORS AND REAGENTS; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PHOSPHODIESTERASE INHIBITORS; PYRAZOLES; ROLIPRAM; SPLEEN; T-LYMPHOCYTES, CYTOTOXIC; TACROLIMUS; THIOPHENES;

EID: 58149474535     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2008.10.005     Document Type: Article

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