-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
10.1038/372425a0 7984236
-
Zhang Y Proenca R Maffei M Barone M Leopold L Friedman JM Positional cloning of the mouse obese gene and its human homologue Nature 1994, 372:425-432 10.1038/372425a0 7984236
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
10.1126/science.7624778 7624778
-
Campfield LA Smith FJ Guisez Y Devos R Burn P Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks Science 1995, 269:546-549 10.1126/science.7624778 7624778
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
3
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
10.1126/science.7624777 7624777
-
Halaas JL Gajiwala KS Maffei M Cohen SL Chait BT Rabinowitz D et al. Weight-reducing effects of the plasma protein encoded by the obese gene Science 1995, 269:543-546 10.1126/science.7624777 7624777
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
-
5
-
-
0032538875
-
Leptin, the product of Ob gene, promotes angiogenesis
-
9815153
-
Bouloumie A Drexler HC Lafontan M Busse R Leptin, the product of Ob gene, promotes angiogenesis Circ Res 1998, 83:1059-1066 9815153
-
(1998)
Circ Res
, vol.83
, pp. 1059-1066
-
-
Bouloumie, A.1
Drexler, H.C.2
Lafontan, M.3
Busse, R.4
-
8
-
-
0030942844
-
The leptin receptor
-
9102398
-
Tartaglia LA The leptin receptor J Biol Chem 1997, 272:6093-6096 9102398
-
(1997)
J Biol Chem
, vol.272
, pp. 6093-6096
-
-
Tartaglia, L.A.1
-
9
-
-
0037146224
-
Leptin - A growth factor in normal and malignant breast cells and for normal mammary gland development
-
12441326
-
Hu X Juneja SC Maihle NJ Cleary MP Leptin - a growth factor in normal and malignant breast cells and for normal mammary gland development J Natl Cancer Inst 2002, 94:1704-1711 12441326
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1704-1711
-
-
Hu, X.1
Juneja, S.C.2
Maihle, N.J.3
Cleary, M.P.4
-
11
-
-
0037169828
-
Identification of leptin receptors in human breast cancer: Functional activity in the T47-D breast cancer cell line
-
10.1016/S0303-7207(01)00678-5 11911959
-
Laud K Gourdou I Pessemesse L Peyrat JP Djiane J Identification of leptin receptors in human breast cancer: Functional activity in the T47-D breast cancer cell line Mol Cell Endocrinol 2002, 188:219-226 10.1016/S0303-7207(01)00678-5 11911959
-
(2002)
Mol Cell Endocrinol
, vol.188
, pp. 219-226
-
-
Laud, K.1
Gourdou, I.2
Pessemesse, L.3
Peyrat, J.P.4
Djiane, J.5
-
12
-
-
0037152340
-
Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: Reciprocal involvement of PKC-alpha and PPAR expression
-
12379472
-
Okumura M Yamamoto M Sakuma H Kojima T Maruyama T Jamali M et al. Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: Reciprocal involvement of PKC-alpha and PPAR expression Biochim Biophys Acta 2002, 1592:107-116 12379472
-
(2002)
Biochim Biophys Acta
, vol.1592
, pp. 107-116
-
-
Okumura, M.1
Yamamoto, M.2
Sakuma, H.3
Kojima, T.4
Maruyama, T.5
Jamali, M.6
-
13
-
-
15144353456
-
Exonic and intronic sequence variation in the human leptin receptor gene (LEPR)
-
9287054
-
Chung WK Power-Kehoe L Chua M Chu F Aronne L Huma Z et al. Exonic and intronic sequence variation in the human leptin receptor gene (LEPR) Diabetes 1997, 46:1509-1511 9287054
-
(1997)
Diabetes
, vol.46
, pp. 1509-1511
-
-
Chung, W.K.1
Power-Kehoe, L.2
Chua, M.3
Chu, F.4
Aronne, L.5
Huma, Z.6
-
14
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
10.1016/0092-8674(95)90151-5 8548812
-
Tartaglia LA Dembski M Weng X Deng N Culpepper J Devos R Identification and expression cloning of a leptin receptor, OB-R Cell 1995, 83:1263-1271 10.1016/0092-8674(95)90151-5 8548812
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
-
16
-
-
0035073893
-
A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women
-
10.1007/s004390100468 11354636
-
Quinton ND Lee AJ Ross RJ Eastell R Blakemore AI A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women Hum Genet 2001, 108:233-236 10.1007/s004390100468 11354636
-
(2001)
Hum Genet
, vol.108
, pp. 233-236
-
-
Quinton, N.D.1
Lee, A.J.2
Ross, R.J.3
Eastell, R.4
Blakemore, A.I.5
-
17
-
-
16544384372
-
Adipocyte expression and circulating levels of leptin increase in both gynaecological and breast cancer patients
-
15138597
-
Tessitore L Vizio B Pesola D Cecchini F Mussa A Argiles JM et al. Adipocyte expression and circulating levels of leptin increase in both gynaecological and breast cancer patients Int J Oncol 2004, 24:1529-1535 15138597
-
(2004)
Int J Oncol
, vol.24
, pp. 1529-1535
-
-
Tessitore, L.1
Vizio, B.2
Pesola, D.3
Cecchini, F.4
Mussa, A.5
Argiles, J.M.6
-
18
-
-
23844456707
-
Serum levels of leptin, insulin, and lipids in relation to breast cancer in china
-
10.1385/ENDO:26:1:019 15805581
-
Han C Zhang HT Du L Liu X Jing J Zhao X et al. Serum levels of leptin, insulin, and lipids in relation to breast cancer in china Endocrine 2005, 26:19-24 10.1385/ENDO:26:1:019 15805581
-
(2005)
Endocrine
, vol.26
, pp. 19-24
-
-
Han, C.1
Zhang, H.T.2
Du, L.3
Liu, X.4
Jing, J.5
Zhao, X.6
-
20
-
-
0033521862
-
Leptin in relation to carcinoma in situ of the breast: A study of pre-menopausal cases and controls
-
10.1002/(SICI)1097-0215(19990209)80:4<523::AID-IJC7>3.0.CO;2-C 9935151
-
Mantzoros CS Bolhke K Moschos S Cramer DW Leptin in relation to carcinoma in situ of the breast: A study of pre-menopausal cases and controls Int J Cancer 1999, 80:523-526 10.1002/ (SICI)1097-0215(19990209)80:4<523::AID-IJC7>3.0.CO;2-C 9935151
-
(1999)
Int J Cancer
, vol.80
, pp. 523-526
-
-
Mantzoros, C.S.1
Bolhke, K.2
Moschos, S.3
Cramer, D.W.4
-
21
-
-
0034847530
-
The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability
-
10.1210/jc.86.9.4434 11549688
-
Yiannakouris N Yannakoulia M Melistas L Chan JL Klimis-Zacas D Mantzoros CS The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability J Clin Endocrinol Metab 2001, 86:4434-4439 10.1210/jc.86.9.4434 11549688
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4434-4439
-
-
Yiannakouris, N.1
Yannakoulia, M.2
Melistas, L.3
Chan, J.L.4
Klimis-Zacas, D.5
Mantzoros, C.S.6
-
22
-
-
33644883030
-
Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma
-
1397853 16504019 10.1186/1471-2407-6-38
-
Snoussi K Strosberg AD Bouaouina N Ben Ahmed S Helal AN Chouchane L Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma BMC Cancer 2006, 6:38 1397853 16504019 10.1186/1471-2407-6-38
-
(2006)
BMC Cancer
, vol.6
, pp. 38
-
-
Snoussi, K.1
Strosberg, A.D.2
Bouaouina, N.3
Ben Ahmed, S.4
Helal, A.N.5
Chouchane, L.6
-
23
-
-
33646530523
-
Relationships among serum leptin, leptin receptor gene polymorphisms, and breast cancer in Korea
-
10.1016/j.canlet.2005.05.041 16011872
-
Woo HY Park H Ki CS Park YL Bae WG Relationships among serum leptin, leptin receptor gene polymorphisms, and breast cancer in Korea Cancer Lett 2006, 237:137-142 10.1016/j.canlet.2005.05.041 16011872
-
(2006)
Cancer Lett
, vol.237
, pp. 137-142
-
-
Woo, H.Y.1
Park, H.2
Ki, C.S.3
Park, Y.L.4
Bae, W.G.5
-
24
-
-
27944480927
-
Cytochrome P4501A1 genetic polymorphisms and breast cancer risk in Nigerian women
-
10.1007/s10549-005-9022-x 16254684
-
Okobia M Bunker C Zmuda J Kammerer C Vogel V Uche E et al. Cytochrome P4501A1 genetic polymorphisms and breast cancer risk in Nigerian women Breast Cancer Res Treat 2005, 94:285-293 10.1007/s10549-005-9022-x 16254684
-
(2005)
Breast Cancer Res Treat
, vol.94
, pp. 285-293
-
-
Okobia, M.1
Bunker, C.2
Zmuda, J.3
Kammerer, C.4
Vogel, V.5
Uche, E.6
-
25
-
-
33745081811
-
Simple tandem repeat (TTTA)n polymorphism in CYP19 (aromatase) gene and breast cancer risk in Nigerian women
-
1475832 16684355 10.1186/1477-3163-5-12
-
Okobia MN Bunker CH Zmuda JM Ezeome ER Anyanwu SN Uche EE et al. Simple tandem repeat (TTTA)n polymorphism in CYP19 (aromatase) gene and breast cancer risk in Nigerian women J Carcinog 2006, 5:12 1475832 16684355 10.1186/1477-3163-5-12
-
(2006)
J Carcinog
, vol.5
, pp. 12
-
-
Okobia, M.N.1
Bunker, C.H.2
Zmuda, J.M.3
Ezeome, E.R.4
Anyanwu, S.N.5
Uche, E.E.6
-
26
-
-
33748874479
-
Case-control study of risk factors for breast cancer in Nigerian women
-
10.1002/ijc.22102 16823837
-
Okobia M Bunker C Zmuda J Kammerer C Vogel V Uche E et al. Case-control study of risk factors for breast cancer in Nigerian women Int J Cancer 2006, 119:2179-2185 10.1002/ijc.22102 16823837
-
(2006)
Int J Cancer
, vol.119
, pp. 2179-2185
-
-
Okobia, M.1
Bunker, C.2
Zmuda, J.3
Kammerer, C.4
Vogel, V.5
Uche, E.6
-
27
-
-
33748344711
-
Anthropometry and breast cancer risk in nigerian women
-
10.1111/j.1075-122X.2006.00304.x 16958966
-
Okobia MN Bunker CH Zmuda JM Osime U Ezeome ER Anyanwu SN et al. Anthropometry and breast cancer risk in nigerian women Breast J 2006, 12:462-466 10.1111/j.1075-122X.2006.00304.x 16958966
-
(2006)
Breast J
, vol.12
, pp. 462-466
-
-
Okobia, M.N.1
Bunker, C.H.2
Zmuda, J.M.3
Osime, U.4
Ezeome, E.R.5
Anyanwu, S.N.6
-
28
-
-
23444460111
-
Genetics of leptin and obesity: A HuGE review
-
10.1093/aje/kwi174 15972940
-
Paracchini V Pedotti P Taioli E Genetics of leptin and obesity: A HuGE review Am J Epidemiol 2005, 162:101-114 10.1093/aje/kwi174 15972940
-
(2005)
Am J Epidemiol
, vol.162
, pp. 101-114
-
-
Paracchini, V.1
Pedotti, P.2
Taioli, E.3
-
29
-
-
84870445213
-
-
International HapMap Project http://www.hapmap.org/cgi-perl/ snp_details?name=rs1137101&source=hapmap_B36
-
International HapMap Project
-
-
-
30
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
10.1038/ng0396-318 8589726
-
Chehab FF Lim ME Lu R Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin Nat Genet 1996, 12:318-320 10.1038/ng0396-318 8589726
-
(1996)
Nat Genet
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
33
-
-
0030980198
-
A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty
-
10.1210/jc.82.4.1066 9100574
-
Mantzoros CS Flier JS Rogol AD A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty J Clin Endocrinol Metab 1997, 82:1066-1070 10.1210/jc.82.4.1066 9100574
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 1066-1070
-
-
Mantzoros, C.S.1
Flier, J.S.2
Rogol, A.D.3
-
34
-
-
0031767057
-
Leptin: In search of role(s) in human physiology and pathophysiology
-
10.1046/j.1365-2265.1998.00571.x 10197068
-
Mantzoros CS Moschos SJ Leptin: In search of role(s) in human physiology and pathophysiology Clin Endocrinol (Oxf) 1998, 49:551-567 10.1046/ j.1365-2265.1998.00571.x 10197068
-
(1998)
Clin Endocrinol (Oxf)
, vol.49
, pp. 551-567
-
-
Mantzoros, C.S.1
Moschos, S.J.2
-
35
-
-
13144293061
-
Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women
-
19406 9482922 10.1073/pnas.95.5.2541
-
Licinio J Negrao AB Mantzoros C Kaklamani V Wong ML Bongiorno PB et al. Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women Proc Natl Acad Sci USA 1998, 95:2541-2546 19406 9482922 10.1073/pnas.95.5.2541
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2541-2546
-
-
Licinio, J.1
Negrao, A.B.2
Mantzoros, C.3
Kaklamani, V.4
Wong, M.L.5
Bongiorno, P.B.6
-
37
-
-
0030753690
-
Serum levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 in healthy centenarians: Relationship with plasma leptin and lipid concentrations, insulin action, and cognitive function
-
10.1210/jc.82.7.2204 9215295
-
Paolisso G Ammendola S Del Buono A Gambardella A Riondino M Tagliamonte MR et al. Serum levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 in healthy centenarians: Relationship with plasma leptin and lipid concentrations, insulin action, and cognitive function J Clin Endocrinol Metab 1997, 82:2204-2209 10.1210/jc.82.7.2204 9215295
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 2204-2209
-
-
Paolisso, G.1
Ammendola, S.2
Del Buono, A.3
Gambardella, A.4
Riondino, M.5
Tagliamonte, M.R.6
-
38
-
-
0029129747
-
Insulin-like growth-factor-binding protein 3 is decreased in early-stage operable pre-menopausal breast cancer
-
10.1002/ijc.2910620306 7543079
-
Bruning PF Van Doorn J Bonfrer JM Van Noord PA Korse CM Linders TC et al. Insulin-like growth-factor-binding protein 3 is decreased in early-stage operable pre-menopausal breast cancer Int J Cancer 1995, 62:266-270 10.1002/ijc.2910620306 7543079
-
(1995)
Int J Cancer
, vol.62
, pp. 266-270
-
-
Bruning, P.F.1
Van Doorn, J.2
Bonfrer, J.M.3
Van Noord, P.A.4
Korse, C.M.5
Linders, T.C.6
-
39
-
-
0031840476
-
Insulin-like growth factor-I in relation to premenopausal ductal carcinoma in situ of the breast
-
10.1097/00001648-199809000-00018 9730040
-
Bohlke K Cramer DW Trichopoulos D Mantzoros CS Insulin-like growth factor-I in relation to premenopausal ductal carcinoma in situ of the breast Epidemiology 1998, 9:570-573 10.1097/00001648-199809000-00018 9730040
-
(1998)
Epidemiology
, vol.9
, pp. 570-573
-
-
Bohlke, K.1
Cramer, D.W.2
Trichopoulos, D.3
Mantzoros, C.S.4
-
41
-
-
0035461331
-
Angiogenic activity of leptin in the chick embryo chorioallantoic membrane is in part mediated by endogenous fibroblast growth factor-2
-
11494053
-
Ribatti D Nico B Belloni AS Vacca A Roncali L Nussdorfer GG Angiogenic activity of leptin in the chick embryo chorioallantoic membrane is in part mediated by endogenous fibroblast growth factor-2 Int J Mol Med 2001, 8:265-268 11494053
-
(2001)
Int J Mol Med
, vol.8
, pp. 265-268
-
-
Ribatti, D.1
Nico, B.2
Belloni, A.S.3
Vacca, A.4
Roncali, L.5
Nussdorfer, G.G.6
-
42
-
-
0033021670
-
Linkages and associations between the leptin receptor (LEPR) gene and human body composition in the Quebec Family Study
-
10.1038/sj.ijo.0800809 10193873
-
Chagnon YC Chung WK Perusse L Chagnon M Leibel RL Bouchard C Linkages and associations between the leptin receptor (LEPR) gene and human body composition in the Quebec Family Study Int J Obes Relat Metab Disord 1999, 23:278-286 10.1038/sj.ijo.0800809 10193873
-
(1999)
Int J Obes Relat Metab Disord
, vol.23
, pp. 278-286
-
-
Chagnon, Y.C.1
Chung, W.K.2
Perusse, L.3
Chagnon, M.4
Leibel, R.L.5
Bouchard, C.6
-
43
-
-
17744381149
-
Associations between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE family study
-
10.1210/jc.85.1.29 10634359
-
Chagnon YC Wilmore JH Borecki IB Gagnon J Perusse L Chagnon M et al. Associations between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE family study J Clin Endocrinol Metab 2000, 85:29-34 10.1210/jc.85.1.29 10634359
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 29-34
-
-
Chagnon, Y.C.1
Wilmore, J.H.2
Borecki, I.B.3
Gagnon, J.4
Perusse, L.5
Chagnon, M.6
|