D2 dopamine receptor activation facilitates endocannabinoid- mediated long-term synaptic depression of GABAergic synaptic transmission in midbrain dopamine neurons via cAMP-protein kinase A signaling

Journal of Neuroscience

Volumn 28, Issue 52, 2008, Pages 14018-14030

  Pan, Bin ^a   Hillard, Cecilia J ^a   Liu, Qing Song ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

cAMP PKA; Dopamine; Endocannabinoid; GABA; Long term depression; Synaptic plasticity

Indexed keywords

CANNABINOID 1 RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE 2 RECEPTOR; ENDOCANNABINOID; METABOTROPIC RECEPTOR 1; 1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 AMINOBUTYRIC ACID; 6 METHYL 2 (PHENYLETHYNYL)PYRIDINE; 6-METHYL-2-(PHENYLETHYNYL)PYRIDINE; 7 (HYDROXYIMINO)CYCLOPROPAN(B)CHROMEN 1A CARBXOYLIC ACID ETHYL ESTER; 7-(HYDROXYIMINO)CYCLOPROPAN(B)CHROMEN-1A-CARBXOYLIC ACID ETHYL ESTER; AMINO ACID RECEPTOR BLOCKING AGENT; BENZOXAZINE DERIVATIVE; CHROMONE DERIVATIVE; COCAINE; DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; DRUG DERIVATIVE; EGTAZIC ACID; EGTAZIC ACID TETRAKIS(ACETOXYMETHYL) ESTER; ENZYME INHIBITOR; MORPHOLINE DERIVATIVE; NAPHTHALENE DERIVATIVE; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME INHIBITION; FEMALE; GABAERGIC TRANSMISSION; LONG TERM DEPRESSION; MALE; MESENCEPHALON; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; VENTRAL TEGMENTUM; ANALYSIS OF VARIANCE; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG COMBINATION; DRUG EFFECT; DRUG POTENTIATION; ELECTROSTIMULATION; IN VITRO STUDY; METABOLISM; METHODOLOGY; MOUSE MUTANT; NERVE CELL; NEWBORN; PATCH CLAMP; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BENZOXAZINES; CHROMONES; COCAINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOPAMINE; DOPAMINE AGENTS; DRUG COMBINATIONS; EGTAZIC ACID; ELECTRIC STIMULATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GAMMA-AMINOBUTYRIC ACID; LONG-TERM SYNAPTIC DEPRESSION; MALE; MESENCEPHALON; MICE; MICE, KNOCKOUT; MORPHOLINES; NAPHTHALENES; NEURONS; PATCH-CLAMP TECHNIQUES; PIPERIDINES; PYRAZOLES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; RECEPTORS, DOPAMINE D2;

EID: 58149373942     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4035-08.2008     Document Type: Article

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