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Volumn 16, Issue 5, 2008, Pages 465-471

Recent advances in hair cell regeneration research

Author keywords

Ear; hair cell; proliferation; regeneration; repair

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; MICRORNA; NOTCH RECEPTOR;

EID: 58149337279     PISSN: 10689508     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOO.0b013e32830f4ab5     Document Type: Review
Times cited : (32)

References (81)
  • 1
    • 63649157952 scopus 로고    scopus 로고
    • Morphological correlates of regeneration and repair
    • Salvi RJ, Fay RR, Popper AN, editors, New York: Springer;
    • Meyers JR, Corwin JT. Morphological correlates of regeneration and repair. In: Salvi RJ, Fay RR, Popper AN, editors. Hair cell regeneration, repair, and protection. New York: Springer; 2008. pp. 39-75.
    • (2008) Hair cell regeneration, repair, and protection , pp. 39-75
    • Meyers, J.R.1    Corwin, J.T.2
  • 2
    • 0024560240 scopus 로고
    • Cell production in the chicken cochlea
    • Katayama A, Corwin JT. Cell production in the chicken cochlea. J Comp Neurol 1989; 281:129-135.
    • (1989) J Comp Neurol , vol.281 , pp. 129-135
    • Katayama, A.1    Corwin, J.T.2
  • 3
    • 0014040729 scopus 로고
    • Development of the inner ear of the mouse: A radioautographic study of terminal mitoses
    • Ruben RJ. Development of the inner ear of the mouse: a radioautographic study of terminal mitoses. Acta Otolaryngol 1967; (Suppl 220):1-44.
    • (1967) Acta Otolaryngol , Issue.SUPPL. 220 , pp. 1-44
    • Ruben, R.J.1
  • 4
    • 0023918917 scopus 로고
    • Regeneration of sensory hair cells after acoustic trauma
    • Corwin JT, Cotanche DA. Regeneration of sensory hair cells after acoustic trauma. Science 1988; 240:1772-1774.
    • (1988) Science , vol.240 , pp. 1772-1774
    • Corwin, J.T.1    Cotanche, D.A.2
  • 5
    • 0024295746 scopus 로고
    • Hair cell regeneration after acoustic trauma in adult Coturnix quail
    • Ryals BM, Rubel EW. Hair cell regeneration after acoustic trauma in adult Coturnix quail. Science 1988; 240:1774-1776.
    • (1988) Science , vol.240 , pp. 1774-1776
    • Ryals, B.M.1    Rubel, E.W.2
  • 6
    • 21044454607 scopus 로고    scopus 로고
    • The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear
    • Mantela J, Jiang Z, Ylikoski J, et al. The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear. Development 2005; 132:2377-2388.
    • (2005) Development , vol.132 , pp. 2377-2388
    • Mantela, J.1    Jiang, Z.2    Ylikoski, J.3
  • 7
    • 13844309351 scopus 로고    scopus 로고
    • Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein
    • Sage C, Huang M, Karimi K, et al. Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science 2005; 307:1114-1118.
    • (2005) Science , vol.307 , pp. 1114-1118
    • Sage, C.1    Huang, M.2    Karimi, K.3
  • 8
    • 33646554480 scopus 로고    scopus 로고
    • Essential role of retinoblastoma protein in mammalian hair cell development and hearing
    • Sage C, Huang M, Vollrath MA, et al. Essential role of retinoblastoma protein in mammalian hair cell development and hearing. Proc Natl Acad Sci USA 2006; 103:7345-7350.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7345-7350
    • Sage, C.1    Huang, M.2    Vollrath, M.A.3
  • 9
    • 38649087620 scopus 로고    scopus 로고
    • Rapid cell-cycle reentry and cell death after acute inactivation of the retinoblastoma gene product in postnatal cochlear hair cells
    • Weber T, Corbett MK, Chow LM, et al. Rapid cell-cycle reentry and cell death after acute inactivation of the retinoblastoma gene product in postnatal cochlear hair cells. Proc Natl Acad Sci USA 2008; 105:781-785.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 781-785
    • Weber, T.1    Corbett, M.K.2    Chow, L.M.3
  • 10
    • 0032933174 scopus 로고    scopus 로고
    • p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
    • Chen P, Segil N. p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti. Development 1999; 126:1581-1590.
    • (1999) Development , vol.126 , pp. 1581-1590
    • Chen, P.1    Segil, N.2
  • 11
    • 0033616695 scopus 로고    scopus 로고
    • Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti
    • Lowenheim H, Furness DN, Kil J, et al. Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti. Proc Natl Acad Sci U S A 1999; 96:4084-4088.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4084-4088
    • Lowenheim, H.1    Furness, D.N.2    Kil, J.3
  • 12
    • 33846982227 scopus 로고    scopus 로고
    • p19(Ink4d)and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis
    • Laine H, Doetzlhofer A, Mantela J, et al. p19(Ink4d)and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis. J Neurosci 2007; 27:1434-1444.
    • (2007) J Neurosci , vol.27 , pp. 1434-1444
    • Laine, H.1    Doetzlhofer, A.2    Mantela, J.3
  • 13
    • 34548490737 scopus 로고    scopus 로고
    • Manipulating cell cycle regulation in the mature cochlea
    • Minoda R, Izumikawa M, Kawamoto K, et al. Manipulating cell cycle regulation in the mature cochlea. Hear Res 2007; 232:44-51.
    • (2007) Hear Res , vol.232 , pp. 44-51
    • Minoda, R.1    Izumikawa, M.2    Kawamoto, K.3
  • 14
    • 13744263559 scopus 로고    scopus 로고
    • Math1 regulates development of the sensory epithelium in the mammalian cochlea
    • Woods C, Montcouquiol M, Kelley MW. Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat Neurosci 2004; 7:1310-1318.
    • (2004) Nat Neurosci , vol.7 , pp. 1310-1318
    • Woods, C.1    Montcouquiol, M.2    Kelley, M.W.3
  • 15
    • 0033546004 scopus 로고    scopus 로고
    • Math1: An essential gene for the generation of inner ear hair cells
    • Bermingham NA, Hassan BA, Price SD, et al. Math1: an essential gene for the generation of inner ear hair cells. Science 1999; 284:1837-1841.
    • (1999) Science , vol.284 , pp. 1837-1841
    • Bermingham, N.A.1    Hassan, B.A.2    Price, S.D.3
  • 16
    • 33846981184 scopus 로고    scopus 로고
    • Zebrafish atoh1 genes: Classic proneural activity in the inner ear and regulation by Fgf and Notch
    • Millimaki BB, Sweet EM, Dhason MS, Riley BB. Zebrafish atoh1 genes: classic proneural activity in the inner ear and regulation by Fgf and Notch. Development 2007; 134:295-305.
    • (2007) Development , vol.134 , pp. 295-305
    • Millimaki, B.B.1    Sweet, E.M.2    Dhason, M.S.3    Riley, B.B.4
  • 17
    • 0036337481 scopus 로고    scopus 로고
    • The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination
    • Chen P, Johnson JE, Zoghbi HY, Segil N. The role of Math1 in inner ear development: uncoupling the establishment of the sensory primordium from hair cell fate determination. Development 2002; 129:2495-2505.
    • (2002) Development , vol.129 , pp. 2495-2505
    • Chen, P.1    Johnson, J.E.2    Zoghbi, H.Y.3    Segil, N.4
  • 18
    • 0034448994 scopus 로고    scopus 로고
    • Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice
    • Lanford PJ, Shailam R, Norton CR, et al. Expression of Math1 and HES5 in the cochleae of wildtype and Jag2 mutant mice. J Assoc Res Otolaryngol 2000; 1:161-171.
    • (2000) J Assoc Res Otolaryngol , vol.1 , pp. 161-171
    • Lanford, P.J.1    Shailam, R.2    Norton, C.R.3
  • 19
    • 27444444919 scopus 로고    scopus 로고
    • Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit
    • Matei V, Pauley S, Kaing S, et al. Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit. Dev Dyn 2005; 234:633-650.
    • (2005) Dev Dyn , vol.234 , pp. 633-650
    • Matei, V.1    Pauley, S.2    Kaing, S.3
  • 20
    • 0035400075 scopus 로고    scopus 로고
    • Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear
    • Zine A, Aubert A, Qiu J, et al. Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear. J Neurosci 2001; 21:4712-4720.
    • (2001) J Neurosci , vol.21 , pp. 4712-4720
    • Zine, A.1    Aubert, A.2    Qiu, J.3
  • 21
    • 33646458009 scopus 로고    scopus 로고
    • BMP-signaling regulates the generation of hair-cells
    • Pujades C, Kamaid A, Alsina B, Giraldez F. BMP-signaling regulates the generation of hair-cells. Dev Biol 2006; 292:55-67.
    • (2006) Dev Biol , vol.292 , pp. 55-67
    • Pujades, C.1    Kamaid, A.2    Alsina, B.3    Giraldez, F.4
  • 22
    • 0037626148 scopus 로고    scopus 로고
    • Expression of Prox1 defines regions of the avian otocyst that give rise to sensory or neural cells
    • Stone JS, Shang JL, Tomarev S. Expression of Prox1 defines regions of the avian otocyst that give rise to sensory or neural cells. J Comp Neurol 2003; 460:487-502.
    • (2003) J Comp Neurol , vol.460 , pp. 487-502
    • Stone, J.S.1    Shang, J.L.2    Tomarev, S.3
  • 23
    • 33846261634 scopus 로고    scopus 로고
    • Atoh1 expression defines activated progenitors and differentiating hair cells during avian hair cell regeneration
    • Cafaro J, Lee GS, Stone JS. Atoh1 expression defines activated progenitors and differentiating hair cells during avian hair cell regeneration. Dev Dyn 2007; 236:156-170.
    • (2007) Dev Dyn , vol.236 , pp. 156-170
    • Cafaro, J.1    Lee, G.S.2    Stone, J.S.3
  • 24
    • 32544457518 scopus 로고    scopus 로고
    • Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of Corti
    • Jones JM, Montcouquiol M, Dabdoub A, et al. Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of Corti. J Neurosci 2006; 26:550-558.
    • (2006) J Neurosci , vol.26 , pp. 550-558
    • Jones, J.M.1    Montcouquiol, M.2    Dabdoub, A.3
  • 25
    • 38349002582 scopus 로고    scopus 로고
    • Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development
    • Raft S, Koundakjian EJ, Quinones H, et al. Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development. Development 2007; 134:4405-4415.
    • (2007) Development , vol.134 , pp. 4405-4415
    • Raft, S.1    Koundakjian, E.J.2    Quinones, H.3
  • 26
    • 34548755017 scopus 로고    scopus 로고
    • Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells
    • Scheffer D, Sage C, Corey D, Pingault V. Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells. FEBS Lett 2007; 581:4651-4656.
    • (2007) FEBS Lett , vol.581 , pp. 4651-4656
    • Scheffer, D.1    Sage, C.2    Corey, D.3    Pingault, V.4
  • 27
    • 0034127584 scopus 로고    scopus 로고
    • Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
    • Zheng JL, Gao WQ. Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat Neurosci 2000; 3:580-586.
    • (2000) Nat Neurosci , vol.3 , pp. 580-586
    • Zheng, J.L.1    Gao, W.Q.2
  • 28
    • 0037705527 scopus 로고    scopus 로고
    • Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1
    • Shou J, Zheng JL, Gao WQ. Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1. Mol Cell Neurosci 2003; 23:169-179.
    • (2003) Mol Cell Neurosci , vol.23 , pp. 169-179
    • Shou, J.1    Zheng, J.L.2    Gao, W.Q.3
  • 29
    • 16244411316 scopus 로고    scopus 로고
    • Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals
    • Izumikawa M, Minoda R, Kawamoto K, et al. Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. Nat Med 2005; 11:271-276.
    • (2005) Nat Med , vol.11 , pp. 271-276
    • Izumikawa, M.1    Minoda, R.2    Kawamoto, K.3
  • 30
    • 33846630878 scopus 로고    scopus 로고
    • Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer
    • Staecker H, Praetorius M, Baker K, Brough DE. Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer. Otol Neurotol 2007; 28:223-231.
    • (2007) Otol Neurotol , vol.28 , pp. 223-231
    • Staecker, H.1    Praetorius, M.2    Baker, K.3    Brough, D.E.4
  • 31
    • 33646164664 scopus 로고    scopus 로고
    • Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear
    • Brooker R, Hozumi K, Lewis J. Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear. Development 2006; 133:1277-1286.
    • (2006) Development , vol.133 , pp. 1277-1286
    • Brooker, R.1    Hozumi, K.2    Lewis, J.3
  • 32
    • 14044258714 scopus 로고    scopus 로고
    • Two contrasting roles for Notch activity in chick inner ear development: Specification of prosensory patches and lateral inhibition of hair-cell differentiation
    • Daudet N, Lewis J. Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation. Development 2005; 132:541-551.
    • (2005) Development , vol.132 , pp. 541-551
    • Daudet, N.1    Lewis, J.2
  • 33
    • 0035957432 scopus 로고    scopus 로고
    • The Notch ligand Jagged1 is required for inner ear sensory development
    • Kiernan AE, Ahituv N, Fuchs H, et al. The Notch ligand Jagged1 is required for inner ear sensory development. Proc Natl Acad Sci USA 2001; 98:3873-3878.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3873-3878
    • Kiernan, A.E.1    Ahituv, N.2    Fuchs, H.3
  • 34
    • 33645758812 scopus 로고    scopus 로고
    • The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear
    • Kiernan AE, Xu J, Gridley T. The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet 2006; 2:e4.
    • (2006) PLoS Genet , vol.2
    • Kiernan, A.E.1    Xu, J.2    Gridley, T.3
  • 35
    • 0032425547 scopus 로고    scopus 로고
    • Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: Evidence from the mind bomb mutant
    • Haddon C, Jiang YJ, Smithers L, Lewis J. Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: evidence from the mind bomb mutant. Development 1998; 125:4637-4644.
    • (1998) Development , vol.125 , pp. 4637-4644
    • Haddon, C.1    Jiang, Y.J.2    Smithers, L.3    Lewis, J.4
  • 36
    • 27644446538 scopus 로고    scopus 로고
    • The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear
    • Kiernan AE, Cordes R, Kopan R, et al. The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development 2005; 132:4353-4362.
    • (2005) Development , vol.132 , pp. 4353-4362
    • Kiernan, A.E.1    Cordes, R.2    Kopan, R.3
  • 37
    • 0033021954 scopus 로고    scopus 로고
    • Notch signalling pathway mediates hair cell development in mammalian cochlea
    • Lanford PJ, Lan Y, Jiang R, et al. Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat Genet 1999; 21:289-292.
    • (1999) Nat Genet , vol.21 , pp. 289-292
    • Lanford, P.J.1    Lan, Y.2    Jiang, R.3
  • 38
    • 0032242705 scopus 로고    scopus 로고
    • Notch signalling and the control of cell fate choices in vertebrates
    • Lewis J. Notch signalling and the control of cell fate choices in vertebrates. Semin Cell Dev Biol 1998; 9:583-589.
    • (1998) Semin Cell Dev Biol , vol.9 , pp. 583-589
    • Lewis, J.1
  • 39
    • 0033779635 scopus 로고    scopus 로고
    • Presenilins are required for gammasecretase cleavage of beta-APP and transmembrane cleavage of Notch-1
    • Zhang Z, Nadeau P, Song W, et al. Presenilins are required for gammasecretase cleavage of beta-APP and transmembrane cleavage of Notch-1. Nat Cell Biol 2000; 2:463-465.
    • (2000) Nat Cell Biol , vol.2 , pp. 463-465
    • Zhang, Z.1    Nadeau, P.2    Song, W.3
  • 40
    • 0033845467 scopus 로고    scopus 로고
    • Notch signaling regulates the pattern of auditory hair cell differentiation in mammals
    • Zine A, Van De Water TR, de Ribaupierre F. Notch signaling regulates the pattern of auditory hair cell differentiation in mammals. Development 2000; 127:3373-3383.
    • (2000) Development , vol.127 , pp. 3373-3383
    • Zine, A.1    Van De Water, T.R.2    de Ribaupierre, F.3
  • 41
    • 30744455741 scopus 로고    scopus 로고
    • Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas
    • Yamamoto N, Tanigaki K, Tsuji M, et al. Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. J Mol Med 2006; 84:37-45.
    • (2006) J Mol Med , vol.84 , pp. 37-45
    • Yamamoto, N.1    Tanigaki, K.2    Tsuji, M.3
  • 42
    • 34250000827 scopus 로고    scopus 로고
    • Multiple roles of Notch signaling in cochlear development
    • TakebayashiS, Yamamoto N, Yabe D, et al. Multiple roles of Notch signaling in cochlear development. Dev Biol 2007; 307:165-178.
    • (2007) Dev Biol , vol.307 , pp. 165-178
    • Takebayashi, S.1    Yamamoto, N.2    Yabe, D.3
  • 43
    • 0032995894 scopus 로고    scopus 로고
    • Delta1 expression during avian hair cell regeneration
    • Stone JS, Rubel EW. Delta1 expression during avian hair cell regeneration. Development 1999; 126:961-973.
    • (1999) Development , vol.126 , pp. 961-973
    • Stone, J.S.1    Rubel, E.W.2
  • 44
    • 39849089205 scopus 로고    scopus 로고
    • Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line
    • Ma EY, Rubel EW, Raible DW. Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line. J Neurosci 2008; 28:2261-2273.
    • (2008) J Neurosci , vol.28 , pp. 2261-2273
    • Ma, E.Y.1    Rubel, E.W.2    Raible, D.W.3
  • 45
    • 36248991735 scopus 로고    scopus 로고
    • Pharmacological inhibition of Notch signaling in the mature guinea pig cochlea
    • Hori R, Nakagawa T, Sakamoto T, et al. Pharmacological inhibition of Notch signaling in the mature guinea pig cochlea. Neuroreport 2007; 18:1911-1914.
    • (2007) Neuroreport , vol.18 , pp. 1911-1914
    • Hori, R.1    Nakagawa, T.2    Sakamoto, T.3
  • 46
    • 36049013648 scopus 로고    scopus 로고
    • Axial patterning in the developing vertebrate inner ear
    • Whitfield TT, Hammond KL. Axial patterning in the developing vertebrate inner ear. Int J Dev Biol 2007; 51:507-520.
    • (2007) Int J Dev Biol , vol.51 , pp. 507-520
    • Whitfield, T.T.1    Hammond, K.L.2
  • 47
    • 33750290919 scopus 로고    scopus 로고
    • Regulation of cell fate in the sensory epithelia of the inner ear
    • Kelley MW. Regulation of cell fate in the sensory epithelia of the inner ear. Nat Rev Neurosci 2006; 7:837-849.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 837-849
    • Kelley, M.W.1
  • 48
    • 36048960746 scopus 로고    scopus 로고
    • Hindbrain signals in otic regionalization: Walk on the wild side
    • Schneider-Maunoury S, Pujades C. Hindbrain signals in otic regionalization: walk on the wild side. Int J Dev Biol 2007; 51:495-506.
    • (2007) Int J Dev Biol , vol.51 , pp. 495-506
    • Schneider-Maunoury, S.1    Pujades, C.2
  • 49
    • 40549101234 scopus 로고    scopus 로고
    • Large scale gene expression profiles of regenerating inner ear sensory epithelia
    • Hawkins RD, Bashiardes S, Powder KE, et al. Large scale gene expression profiles of regenerating inner ear sensory epithelia. PLoS ONE 2007; 2: e525.
    • (2007) PLoS ONE , vol.2
    • Hawkins, R.D.1    Bashiardes, S.2    Powder, K.E.3
  • 50
    • 35048862372 scopus 로고    scopus 로고
    • Toward a systems biology of mouse inner ear organogenesis: Gene expression pathways, patterns and network analysis
    • Sajan SA, Warchol ME, Lovett M. Toward a systems biology of mouse inner ear organogenesis: gene expression pathways, patterns and network analysis. Genetics 2007; 177:631-653.
    • (2007) Genetics , vol.177 , pp. 631-653
    • Sajan, S.A.1    Warchol, M.E.2    Lovett, M.3
  • 51
    • 3142726606 scopus 로고    scopus 로고
    • Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning
    • Ambros V, Lee RC. Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning. Methods Mol Biol 2004; 265:131-158.
    • (2004) Methods Mol Biol , vol.265 , pp. 131-158
    • Ambros, V.1    Lee, R.C.2
  • 53
    • 41149088892 scopus 로고    scopus 로고
    • Micromanaging regeneration
    • Tanaka EM, Weidinger G. Micromanaging regeneration. Genes Dev 2008; 22:700-705.
    • (2008) Genes Dev , vol.22 , pp. 700-705
    • Tanaka, E.M.1    Weidinger, G.2
  • 54
    • 41149130838 scopus 로고    scopus 로고
    • Fgf-dependent depletion of micro-RNA-133 promotes appendage regeneration in zebrafish
    • Yin VP, Thomson JM, Thummel R, et al. Fgf-dependent depletion of micro-RNA-133 promotes appendage regeneration in zebrafish. Genes Dev 2008; 22:728-733.
    • (2008) Genes Dev , vol.22 , pp. 728-733
    • Yin, V.P.1    Thomson, J.M.2    Thummel, R.3
  • 55
    • 34248682652 scopus 로고    scopus 로고
    • MicroRNAs and regenerative medicine
    • Yang Z, Wu J. MicroRNAs and regenerative medicine. DNA Cell Biol 2007; 26:257-264.
    • (2007) DNA Cell Biol , vol.26 , pp. 257-264
    • Yang, Z.1    Wu, J.2
  • 56
    • 34548649007 scopus 로고    scopus 로고
    • MicroRNAs and regeneration: Let-7 members as potential regulators of dedifferentiation in lens and inner ear hair cell regeneration of the adult newt
    • Tsonis PA, Call MK, Grogg MW, et al. MicroRNAs and regeneration: Let-7 members as potential regulators of dedifferentiation in lens and inner ear hair cell regeneration of the adult newt. Biochem Biophys Res Commun 2007; 362:940-945.
    • (2007) Biochem Biophys Res Commun , vol.362 , pp. 940-945
    • Tsonis, P.A.1    Call, M.K.2    Grogg, M.W.3
  • 57
    • 34447626657 scopus 로고    scopus 로고
    • An in vitro model system to study gene therapy in the human inner ear
    • Kesser BW, Hashisaki GT, Fletcher K, et al. An in vitro model system to study gene therapy in the human inner ear. Gene Ther 2007; 14:1121-1131.
    • (2007) Gene Ther , vol.14 , pp. 1121-1131
    • Kesser, B.W.1    Hashisaki, G.T.2    Fletcher, K.3
  • 58
    • 38649123054 scopus 로고    scopus 로고
    • Advances in molecular and cellular therapies for hearing loss
    • Hildebrand MS, Newton SS, Gubbels SP, et al. Advances in molecular and cellular therapies for hearing loss. Mol Ther 2008; 16:224-236.
    • (2008) Mol Ther , vol.16 , pp. 224-236
    • Hildebrand, M.S.1    Newton, S.S.2    Gubbels, S.P.3
  • 59
    • 0001400773 scopus 로고    scopus 로고
    • Glial growth factor enhances supporting cell proliferation in rodent vestibular epithelia cultured in isolation
    • Gu R, Marchionni M, Corwin JT. Glial growth factor enhances supporting cell proliferation in rodent vestibular epithelia cultured in isolation. Soc Neurosci Abstr 1996; 21.
    • (1996) Soc Neurosci Abstr , pp. 21
    • Gu, R.1    Marchionni, M.2    Corwin, J.T.3
  • 60
    • 0000729268 scopus 로고    scopus 로고
    • Age-related decreases in proliferation within isolated mammalian vestibular epithelia cultured in control and glial growth factor 2 medium
    • Gu R, Marchionni M, Corwin JT. Age-related decreases in proliferation within isolated mammalian vestibular epithelia cultured in control and glial growth factor 2 medium. Assoc Res Otolaryngol Abstr 1997; 20.
    • (1997) Assoc Res Otolaryngol Abstr , pp. 20
    • Gu, R.1    Marchionni, M.2    Corwin, J.T.3
  • 61
    • 34147118985 scopus 로고    scopus 로고
    • Proliferative responses to growth factors decline rapidly during postnatal maturation of mammalian hair cell epithelia
    • Gu R, Montcouquiol M, Marchionni M, Corwin JT. Proliferative responses to growth factors decline rapidly during postnatal maturation of mammalian hair cell epithelia. Eur J Neurosci 2007; 25:1363-1372.
    • (2007) Eur J Neurosci , vol.25 , pp. 1363-1372
    • Gu, R.1    Montcouquiol, M.2    Marchionni, M.3    Corwin, J.T.4
  • 62
    • 0035109615 scopus 로고    scopus 로고
    • Brief treatments with forskolin enhance s-phase entry in balance epithelia from the ears of rats
    • Montcouquiol M, Corwin JT. Brief treatments with forskolin enhance s-phase entry in balance epithelia from the ears of rats. J Neurosci 2001; 21:974-982.
    • (2001) J Neurosci , vol.21 , pp. 974-982
    • Montcouquiol, M.1    Corwin, J.T.2
  • 63
    • 0035863080 scopus 로고    scopus 로고
    • Intracellular signals that control cell proliferation in mammalian balance epithelia: Key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protein kinase
    • Montcouquiol M, Corwin JT. Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protein kinase. J Neurosci 2001; 21:570-580.
    • (2001) J Neurosci , vol.21 , pp. 570-580
    • Montcouquiol, M.1    Corwin, J.T.2
  • 64
    • 0033306426 scopus 로고    scopus 로고
    • Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage
    • Zheng JL, Frantz G, Lewis AK, et al. Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage. J Neurocytol 1999; 28:901-912.
    • (1999) J Neurocytol , vol.28 , pp. 901-912
    • Zheng, J.L.1    Frantz, G.2    Lewis, A.K.3
  • 65
    • 0030728956 scopus 로고    scopus 로고
    • Analysis of rat vestibular hair cell development and regeneration using calretinin as an early marker
    • Zheng JL, Gao WQ. Analysis of rat vestibular hair cell development and regeneration using calretinin as an early marker. J Neurosci 1997; 17:8270-8282.
    • (1997) J Neurosci , vol.17 , pp. 8270-8282
    • Zheng, J.L.1    Gao, W.Q.2
  • 66
    • 33847186324 scopus 로고    scopus 로고
    • Developmental changes in cell-extracellular matrix interactions limit proliferation in the mammalian inner ear
    • Davies D, Magnus C, Corwin JT. Developmental changes in cell-extracellular matrix interactions limit proliferation in the mammalian inner ear. Eur J Neurosci 2007; 25:985-998.
    • (2007) Eur J Neurosci , vol.25 , pp. 985-998
    • Davies, D.1    Magnus, C.2    Corwin, J.T.3
  • 67
    • 34247391143 scopus 로고    scopus 로고
    • Shape change controls supporting cell proliferation in lesioned mammalian balance epithelium
    • Meyers JR, Corwin JT. Shape change controls supporting cell proliferation in lesioned mammalian balance epithelium. J Neurosci 2007; 27:4313-4325.
    • (2007) J Neurosci , vol.27 , pp. 4313-4325
    • Meyers, J.R.1    Corwin, J.T.2
  • 68
    • 36749051725 scopus 로고    scopus 로고
    • Inner ear hair cells produced in vitro by a mesenchymal-to-epithelial transition
    • Hu Z, Corwin JT. Inner ear hair cells produced in vitro by a mesenchymal-to-epithelial transition. Proc Natl Acad Sci USA 2007; 104:16675-16680.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16675-16680
    • Hu, Z.1    Corwin, J.T.2
  • 69
    • 33947326091 scopus 로고    scopus 로고
    • Cell division and maintenance of epithelial integrity in the deafened auditory epithelium
    • Kim YH, Raphael Y. Cell division and maintenance of epithelial integrity in the deafened auditory epithelium. Cell Cycle 2007; 6:612-619.
    • (2007) Cell Cycle , vol.6 , pp. 612-619
    • Kim, Y.H.1    Raphael, Y.2
  • 70
    • 44649129053 scopus 로고    scopus 로고
    • Response of the flat cochlear epithelium to forced expression of Atoh1
    • Izumikawa M, Batts SA, Miyazawa T, et al. Response of the flat cochlear epithelium to forced expression of Atoh1. Hear Res 2008; 240:52-56.
    • (2008) Hear Res , vol.240 , pp. 52-56
    • Izumikawa, M.1    Batts, S.A.2    Miyazawa, T.3
  • 71
    • 2642666080 scopus 로고
    • Cell shape controls terminal differentiation of human epidermal keratinocytes
    • Watt FM, Jordan PW, O'Neill CH. Cell shape controls terminal differentiation of human epidermal keratinocytes. Proc Natl Acad Sci U S A 1988; 85:5576-5580.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 5576-5580
    • Watt, F.M.1    Jordan, P.W.2    O'Neill, C.H.3
  • 72
    • 34548514491 scopus 로고    scopus 로고
    • Closure of supporting cell scar formations requires dynamic actin mechanisms
    • HordichokAJ, Steyger PS. Closure of supporting cell scar formations requires dynamic actin mechanisms. Hear Res 2007; 232:1-19.
    • (2007) Hear Res , vol.232 , pp. 1-19
    • Hordichok, A.J.1    Steyger, P.S.2
  • 73
    • 0142073815 scopus 로고    scopus 로고
    • Pluripotent stem cells from the adult mouse inner ear
    • Li H, Liu H, Heller S. Pluripotent stem cells from the adult mouse inner ear. Nat Med 2003; 9:1293-1299.
    • (2003) Nat Med , vol.9 , pp. 1293-1299
    • Li, H.1    Liu, H.2    Heller, S.3
  • 74
    • 34347325032 scopus 로고    scopus 로고
    • Isolation, growth and differentiation of hair cell progenitors from the newborn rat cochlear greater epithelial ridge
    • Zhang Y, Zhai SQ, Shou J, et al. Isolation, growth and differentiation of hair cell progenitors from the newborn rat cochlear greater epithelial ridge. J Neurosci Methods 2007; 164:271-279.
    • (2007) J Neurosci Methods , vol.164 , pp. 271-279
    • Zhang, Y.1    Zhai, S.Q.2    Shou, J.3
  • 75
    • 33846785438 scopus 로고    scopus 로고
    • Differential distribution of stem cells in the auditory and vestibular organs of the inner ear
    • OshimaK, Grimm CM, CorralesCE, et al. Differential distribution of stem cells in the auditory and vestibular organs of the inner ear. J Assoc Res Otolaryngol 2007; 8:18-31.
    • (2007) J Assoc Res Otolaryngol , vol.8 , pp. 18-31
    • Oshima, K.1    Grimm, C.M.2    Corrales, C.E.3
  • 76
    • 33744493107 scopus 로고    scopus 로고
    • Characterization of proliferating cells from newborn mouse cochleae
    • Wang Z, Jiang H, Yan Y, et al. Characterization of proliferating cells from newborn mouse cochleae. Neuroreport 2006; 17:767-771.
    • (2006) Neuroreport , vol.17 , pp. 767-771
    • Wang, Z.1    Jiang, H.2    Yan, Y.3
  • 77
    • 33745577647 scopus 로고    scopus 로고
    • Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells
    • White PM, Doetzlhofer A, Lee YS, et al. Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. Nature 2006; 441:984-987.
    • (2006) Nature , vol.441 , pp. 984-987
    • White, P.M.1    Doetzlhofer, A.2    Lee, Y.S.3
  • 78
    • 0344633590 scopus 로고    scopus 로고
    • Generation of hair cells by stepwise differentiation of embryonic stem cells
    • Li H, Roblin G, Liu H, Heller S. Generation of hair cells by stepwise differentiation of embryonic stem cells. Proc Natl Acad Sci USA 2003; 100:13495-13500.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13495-13500
    • Li, H.1    Roblin, G.2    Liu, H.3    Heller, S.4
  • 79
    • 33845865292 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells
    • Jeon SJ, Oshima K, Heller S, Edge AS. Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells. Mol Cell Neurosci 2007; 34:59-68.
    • (2007) Mol Cell Neurosci , vol.34 , pp. 59-68
    • Jeon, S.J.1    Oshima, K.2    Heller, S.3    Edge, A.S.4
  • 80
    • 33847683049 scopus 로고    scopus 로고
    • Differentiation of adult mouse olfactory precursor cells into hair cells in vitro
    • Doyle KL, Kazda A, Hort Y, et al. Differentiation of adult mouse olfactory precursor cells into hair cells in vitro. Stem Cells 2007; 25:621-627.
    • (2007) Stem Cells , vol.25 , pp. 621-627
    • Doyle, K.L.1    Kazda, A.2    Hort, Y.3
  • 81
    • 0036940844 scopus 로고    scopus 로고
    • Embryonic inner ear cells reaggregate into specific patterns in vitro
    • Bianchi LM, Person AL, Penney EB. Embryonic inner ear cells reaggregate into specific patterns in vitro. J Assoc Res Otolaryngol 2002; 3:418-429.
    • (2002) J Assoc Res Otolaryngol , vol.3 , pp. 418-429
    • Bianchi, L.M.1    Person, A.L.2    Penney, E.B.3


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