Changes in dipole membrane potential at the mouse blood-brain barrier enhance the transport of 99mTechnetium Sestamibi more than inhibiting Abcb1, Abcc1, or Abcg2

Journal of Neurochemistry

Volumn 108, Issue 3, 2009, Pages 767-775

  Cattelotte, Julie ^b   Tournier, Nicolas ^b   Rizzo Padoin, Nathalie ^c   Schinkel, Alfred H ^d   Scherrmann, Jean Michel ^b   Cisternino, Salvatore ^a,b,e  

^a HÔPITAL FERNAND WIDAL   (France)

^b INSERM   (France)

^c HÔPITAL LARIBOISIÈRE   (France)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

^e HÔPITAL JEAN VERDIER   (France)

Author keywords

99mTc Sestamibi; Blood brain barrier; Membrane potential; Mrp1; Organic cation transporter; P glycoprotein

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; CARNITINE; DIPHENHYDRAMINE; ELACRIDAR; GLYCOPROTEIN P; GUANIDINE; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MULTIDRUG RESISTANCE PROTEIN 1; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 2; ORGANIC CATION TRANSPORTER 3; PHLORETIN; TETRYLAMMONIUM; VALSPODAR; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PERFUSION; CONTROLLED STUDY; DIFFUSION; DIPOLE; DRUG BINDING; DRUG EFFECT; DRUG UPTAKE; MALE; MEMBRANE POTENTIAL; MOUSE; NEUROIMAGING; NONHUMAN; PRIORITY JOURNAL;

ALGORITHMS; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOOD-BRAIN BARRIER; CALCIUM CHANNEL BLOCKERS; CARRIER PROTEINS; DIFFUSION; ENDOTHELIAL CELLS; MALE; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PERFUSION; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M SESTAMIBI; VERAPAMIL;

MUS;

EID: 58149333251     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05832.x     Document Type: Article

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