A transmembrane residue influences the interaction of propofol with the strychnine-sensitive glycine α1 and α1β receptor

Anesthesia and Analgesia

Volumn 107, Issue 6, 2008, Pages 1875-1883

  Ahrens, Jörg ^a   Leuwer, Martin ^b   Stachura, Sina ^a   Krampfl, Klaus ^a   Belelli, Delia ^c   Lambert, Jeremy J ^c   Haeseler, Gertrud ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE ALPHA1 BETA RECEPTOR; GLYCINE ALPHA1 RECEPTOR; GLYCINE RECEPTOR; ISOLEUCINE; METHIONINE; PROPOFOL; SERINE; STRYCHNINE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID A RECEPTOR; GLRB PROTEIN, HUMAN; GLYCINE RECEPTOR ALPHA1; INTRAVENOUS ANESTHETIC AGENT;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ARTICLE; BETA CHAIN; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG RECEPTOR BINDING; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; MUTANT; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; WILD TYPE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANESTHETICS, INTRAVENOUS; CELLS, CULTURED; HUMANS; MUTAGENESIS, SITE-DIRECTED; PROPOFOL; RECEPTORS, GABA-A; RECEPTORS, GLYCINE; STRUCTURE-ACTIVITY RELATIONSHIP; STRYCHNINE;

EID: 58149308246     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e3181875a31     Document Type: Article

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