Local exposure of bone components to injured soft tissue induces Toll-like receptor 4-dependent systemic inflammation with acute lung injury

Shock

Volumn 30, Issue 6, 2008, Pages 686-691

  Kobbe, Philipp ^a,b   Kaczorowski, David J ^a   Vodovotz, Yoram ^a   Tzioupis, Christopher H ^a   Mollen, Kevin P ^a   Billiar, Timothy R ^a   Pape, Hans Christoph ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Bone marrow; Long bone fracture; Multiple organ failure; Pseudofracture model; Soft tissue injury; Toll like receptor 4

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; MYELOPEROXIDASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BONE MARROW; BONE MARROW CELL; C3H MOUSE; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EUTHANASIA; FRACTURE; INFLAMMATION; LUNG LAVAGE; MALE; MOUSE; MUSCLE INJURY; NONHUMAN; PERMEABILITY BARRIER; SIGNAL TRANSDUCTION; SOFT TISSUE INJURY; SUPERNATANT; TISSUE INJURY;

ACUTE LUNG INJURY; ANIMALS; FEMORAL FRACTURES; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-6; LUNG; MALE; MICE; MICE, MUTANT STRAINS; MUTATION; PEROXIDASE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58149262632     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31816f257e     Document Type: Article

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