Real-time detection of BRCA1 gene mutations using a monolithic silicon optocoupler array

Biosensors and Bioelectronics

Volumn 24, Issue 5, 2009, Pages 1341-1347

  Mavrogiannopoulou, Elissavet ^a   Petrou, Panagiota S ^a   Kakabakos, Sotirios E ^a   Misiakos, Konstantinos ^b  

^a Immunoassay/Immunosensors Lab   (Greece)

^b INSTITUTE OF MICROELECTRONICS   (Greece)

Author keywords

BRCA1 mutation detection; Fluorescent probes; Monolithic silicon optocoupler; Real time hybridization monitoring

Indexed keywords

ABSORPTION MAXIMUMS; BIOANALYTICAL; BRCA1 GENES; BRCA1 MUTATION DETECTION; COMPLEMENTARY SEQUENCES; COUPLING EFFICIENCIES; DEHYBRIDIZATION; DETECTION LIMITS; DISSOCIATION KINETICS; EMISSION MAXIMUMS; FLUORESCENT PROBES; FULLY INTEGRATED; MONOLITHIC SILICON OPTOCOUPLER; MUTANT SEQUENCES; NEW GENERATIONS; OPTO COUPLERS; REAL TIMES; REAL-TIME HYBRIDIZATION MONITORING; SILICON TECHNOLOGIES; SINGLE CHIPS; TIME DETECTIONS; TIME SIGNALS; TRANSDUCER ARRAYS;

FLUORESCENCE; LIGHT; LIGHT EMITTING DIODES; LIGHT SOURCES; LIGHTING; NONMETALS; NUCLEOTIDES; OLIGONUCLEOTIDES; OPTOELECTRONIC DEVICES; PHYSICAL OPTICS; SEMICONDUCTING SILICON COMPOUNDS; SIGNAL DETECTION; TRANSDUCERS;

WAVEGUIDE COUPLERS;

BRCA1 PROTEIN; OLIGONUCLEOTIDE;

ANTIBODY LABELING; ARTICLE; BREAST CANCER; CANCER CELL; CONCENTRATION (PARAMETERS); DEVICE; DISEASE PREDISPOSITION; DNA HYBRIDIZATION; DNA MICROARRAY; DNA SEQUENCE; FLUORESCENT ANTIBODY TECHNIQUE; GENE MUTATION; GENE SEQUENCE; GENETIC CODE; HYBRIDIZATION; LIGHT EMITTING DIODE; MONOLITHIC SILICON OPTOCOUPLER; NONHUMAN; ONCOGENE; OVARY CANCER; POINT OF CARE TESTING; REAL TIME POLYMERASE CHAIN REACTION; TRANSDUCER;

BIOSENSING TECHNIQUES; BRCA1 PROTEIN; COMPUTER SYSTEMS; DNA MUTATIONAL ANALYSIS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; GENES, BRCA1; IN SITU HYBRIDIZATION, FLUORESCENCE; OPTICAL DEVICES; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SILICON;

EID: 58149250178     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bios.2008.07.061     Document Type: Article

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