Improvement of Dendrobium nobile Lindl. alkaloids on cognitive deficit in rats induced by lipopolysaccharides

Chinese Journal of Pharmacology and Toxicology

Volumn 22, Issue 6, 2008, Pages 406-411

  Chen, Jian Wei ^a,b   Ma, Hu ^a   Huang, Xie Nan ^a   Gong, Qi Hai ^a   Wu, Qin ^a   Shi, Jing Shan ^a  

^a ZUNYI MEDICAL UNIVERSITY   (China)

^b BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Alkaloid; Amyloid beta protein; Dendrobium nobile Lindl.; Learning; Lipopolysaccharides; Memory

Indexed keywords

ALKALOID; AMYLOID BETA PROTEIN[1-42]; CASPASE 3; CASPASE 8; IBUPROFEN; LIPOPOLYSACCHARIDE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DENDROBIUM; DENDROBIUM NOBILE; DRUG DOSE COMPARISON; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING DISORDER; MALE; MEMORY DISORDER; NERVE CELL NECROSIS; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPATIAL MEMORY;

DENDROBIUM NOBILE; RATTUS;

EID: 58149237060     PISSN: 10003002     EISSN: None     Source Type: Journal    
DOI: 10.3867/j.issn.1000-3002.2008.06.002     Document Type: Article

References (13)

1. Standridge JB. Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease [J]. Curr Alzheimer Res, 2006, 3(2):95-108.
2. Lin P, Bi ZM, Xu H, Wang ZT, Xu LS. Advances in studies on pharmacology of plants from Dendrobium Sw. [J]. Chin Tradit Herb Drugs, 2003, 34(11):S19-S22.
3. Yu MJ, Meng QH, Huang DY, Zhao YP. Studies on the active components and pharmacological action of Dendrobium plants [J]. Chin Tradit Pat Med, 2003, 25(11):918-921.
4. Bao XM, Shu SY. Stereotaxic Atlas of Rat's Brain [M]. Beijing: People's Medical Publishing House, 1991:46-54.
5. Gong QH, Wu Q, Huang XN, Sun AS, Shi JS. Protective effects of Ginkgo biloba leaf extract on aluminum-induced brain dysfunction in rats [J]. Life Sci, 2005, 77(2):140-148.
6. Luo C, Wu Q, Huang XN, Sun AS, Shi JS. Ginkgo biloba leaf extract enhances levels of caspase-3 and amyloid precursor protein in normal rat hippocampus [J]. Acta Pharmacol Sin, 2003, 24(2):152-156.
7. Gong QH, Huang B, Xie XL, Liu Q, Chen JW, Qin N, et al. Improvement of Ginkgo biloba leaf extract on memory deficit induced by bradykinin in rats [J]. Chin J Pharmacol Toxicol, 2008, 22(3):170-174.
8. Rogers J, Webster S, Lue LF, Brachova L, Civin WH, Emmerling M, et al. Inflammation and Alzheimer's disease pathogenesis [J]. Neurobiol Aging, 1996, 17(5):681-686.
9. Hauss-Wegrzyniak B, Dobrzanski P, Stoehr JD, Wenk GL. Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease [J]. Brain Res, 1998, 780(2):294-303.
10. Miklossy J, Kis A, Radenovic A, Miller L, Forro L, Martins R, et al. Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes [J]. Neurobiol Aging, 2006, 27(2):228-236.
11. 40 at the C terminus: implications for Aβ aggregation and toxicity [J]. J Mol Biol, 2006, 364(5):853-862.
12. Lu DC, Soriano S, Bredesen DE, Koo EH. Caspase cleavage of the amyloid precursor protein modulates amyloid β-protein toxicity [J]. J Neurochem, 2003, 87(3):733-741.
13. Rohn TT, Head E, Nesse WH, Cotman CW, Cribbs DH. Activation of caspase-8 in the Alzheimer's disease brain [J]. Neurobiol Dis, 2001, 8(6):1006-1016.