Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles

PLoS Pathogens

Volumn 4, Issue 12, 2008, Pages

  Thuong, Nguyen Thuy Thuong ^a,b   Dunstan, Sarah J ^a,c   Chau, Tran Thi Hong ^b   Thorsson, Vesteinn ^d   Simmons, Cameron P ^a,c   Quyen, Nguyen Than Ha ^a,b   Thwaites, Guy E ^e   Lan, Nguyen Thi Ngoc ^f   Hibberd, Martin ^g   Teo, Yik Y ^h   Seielstad, Mark ^g   Aderem, Alan ^d   Farrar, Jeremy J ^a,c   Hawn, Thomas R ⁱ  

^a OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^b UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f Pham Ngoc Thach Hospital   (Viet Nam)

^g GENOME INSTITUTE OF SINGAPORE   (Singapore)

^h UNIVERSITY OF OXFORD   (United Kingdom)

ⁱ UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CCL1 CHEMOKINE; CD134 ANTIGEN; CXCL11 CHEMOKINE; CXCL2 CHEMOKINE; EPIDERMAL GROWTH FACTOR; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE CHEMOTACTIC PROTEIN 2; HERMES ANTIGEN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; JAGGED1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MANGANESE SUPEROXIDE DISMUTASE; MATRIX METALLOPROTEINASE 19; MONOCYTE CHEMOTACTIC PROTEIN 2; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PENTAXIN; PLASMINOGEN ACTIVATOR; PROSTAGLANDIN SYNTHASE; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; UNINDEXED DRUG; CCL1 PROTEIN, HUMAN; MESSENGER RNA;

ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA POLYMORPHISM; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HOST SUSCEPTIBILITY; HUMAN; IMMUNE RESPONSE GENE; INNATE IMMUNITY; LUNG TUBERCULOSIS; MACROPHAGE; MICROARRAY ANALYSIS; PHENOTYPE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; TUBERCULOSIS; TUBERCULOUS MENINGITIS; CLUSTER ANALYSIS; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETIC DATABASE; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY;

MYCOBACTERIUM TUBERCULOSIS;

CASE-CONTROL STUDIES; CHEMOKINE CCL1; CLUSTER ANALYSIS; DATABASES, GENETIC; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MYCOBACTERIUM TUBERCULOSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; TUBERCULOSIS; TUBERCULOSIS, MENINGEAL; TUBERCULOSIS, PULMONARY;

EID: 58149216756     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000229     Document Type: Article

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