Mitochondria influence Fas expression in GP120-induced apoptosis of neuronal cells

International Journal of Neuroscience

Volumn 119, Issue 2, 2009, Pages 157-165

  Thomas, Sunil ^a,b   Mayer, Lloyd ^b   Sperber, Kirk ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Apoptosis; Caspase; Dementia; Fas; HIV; Mitochondria

Indexed keywords

BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; CASPASE 8; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GLYCOPROTEIN GP 120;

APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CELL DEATH; CONTROLLED STUDY; DEMENTIA; DOWN REGULATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NERVE CELL; NEUROBLASTOMA CELL; OUTCOME ASSESSMENT; PROTEIN EXPRESSION;

AIDS DEMENTIA COMPLEX; ANTIGENS, CD95; APOPTOSIS; BRAIN; CASPASE 8; CELL LINE, TUMOR; DOWN-REGULATION; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MITOCHONDRIA; NERVE DEGENERATION; NEURONS; UP-REGULATION;

EID: 58149215844     PISSN: 00207454     EISSN: 15635279     Source Type: Journal    
DOI: 10.1080/00207450802335537     Document Type: Article

References (25)

1. Ameison, J. C., & Capron, A. (1991). Cell dysfunction and depletion in AIDS: The programmed cell death hypothesis. Immunology Today, 12, 102-105.
2. Badley, A. D., Pilon, A. A., Landay, A., & Lynch, D. H. (2000). Mechanisms of HIV-associated lymphocyte apoptosis. Blood, 96, 2951-2964.
3. Casha, S., Yu, W. R., & Fehlings, M. G. (2005). FAS deficiency reduces apoptosis, spares axons and improves function after spinal cord injury. Experimental Neurology, 196, 390-400.
4. Castedo, M., Perfettini, J. L., Andreau, K., Roumier, T., Piacentini, M., & Kroemer, G. (2003). Mitochondrial apoptosis induced by the HIV-1 envelope. Annals of New York Academy of Science, 1010, 19-28.
5. Chandra, D., Choy, G., Deng, X., Bhatia, B., Daniel, P., & Tang, D. G. (2004). Association of active caspase-8 with the mitochondrial membrane during apoptosis: Potential roles in cleaving BAP31 and caspase-3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death. Molecular Cell Biology, 24, 6592-6607.
6. Damdimopoulos, A. E., Miranda-Vizuete, A., Pelto-Huikko, M., Gustafsson, J. A., & Spyrou, G. (2002). Human mitochondrial thioredoxin. Involvement in mitochondrialmembrane potential and cell death. Journal of Biological Chemistry, 277, 33249-33257.
7. Desbarats, J., Freed, J. H., Campbell, P. A., & Newell, M. K. (1996). Fas (CD95) expression and death-mediating function are induced by CD4 cross-linking on CD4+ T cells. Proceedings of the National Academy of Sciences USA, 93, 11014-11018.
8. Dianzani, U., Bensi, T., Savarino, A., Sametti, S., Indelicato, M., Mesturini, R., et al. (2003). Role of Fas in HIV infection. Current HIV Research, 1, 405-417.
9. Garden, G. A., Budd, S. L., Tsai, E., Hanson, L., Kaul, M., D'Emilia, D. M., et al. (2002). Caspase cascades in human immunodeficiency virus-associated neurodegeneration. Journal of Neuroscience, 22, 4015-4024.
10. Green, D. R., & Kroemer, G. (2004). The pathophysiology of mitochondrial cell death. Science, 305, 626-629.
11. Huang, H. L., Fang, L. W., Lu, S. P., Chou, C. K., Luh, T. Y., & Lai, M. Z. (2003). DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation. Oncogene, 22, 8168-8177.
12. Katsikis, P. D., Wunderlich, E. S., Smith, C. A., Herzenberg, L. A., & Herzenberg, L. A. (1995). Fas antigen stimulation induces marked apoptosis of T Lymphocytes in human immunodeficiency virus-infected individuals. Journal of Experimental Medicine, 181, 2029-2026.
13. Kaul, M., Garden, G. A., & Lipton, S. A. (2001). Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature, 410, 988-994.
14. Kaul, M., & Lipton, S. A. (1999). Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proceedings of the National Academy of Sciences USA, 96, 8212-8216.
15. Lipton, S. A. (1992). Memantine prevents HIV coat protein-induced neuronal injury in vitro. Neurology, 42, 1403-1405.
16. Lipton, S. A., & Gendelman, H. E. (1995). Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome. New England Journal of Medicine, 332, 934-940.
17. McArthur, J. C., Hoover, D. R., Bacellar, H., Miller, E. N., Cohen, B. A., Becker, J. T., et al. (1993). Dementia in AIDS patients: Incidence and risk factors. Multicenter AIDS Cohort Study. Neurology, 43, 2245-2252.
18. McIntosh, T. K. (1994). Neurochemical sequelae of traumatic brain injury: Therapeutic implications. Cerebrovascular Brain Metabolism Review, 6, 109-162.
19. Ohmichi, M., Matuoka, K., Takenawa, T., & Saltiel, A. R. (1994). Growth factors differentially stimulate the phosphorylation of Shc proteins and their association with Grb2 in PC-12 pheochromocytoma cells. Journal of Biological Chemistry, 269, 1143-1148.
20. Qiu, J., Whalen, M. J., Lowenstein, P., Fiskum, G., Fahy, B., Darwish, R., et al. (2002). Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans. Journal of Neuroscience, 22, 3504-3511.
21. Raoul, C., Estevez, A. G., Nishimune, H., Cleveland, D. W., deLapeyriere, O., Henderson, C. E., et al. (2002). Motoneuron death triggered by a specific pathway downstream of Fas. Potentiation by ALS-linked SOD1 mutations. Neuron, 35, 1067-1083.
22. Sas, K., Robotka, H., Toldi, J., & Vecsei, L. (2007). Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders. Journal of Neurological Science, 257, 221-239.
23. Shi, B., De Girolami, U., He, J., Wang, S., Lorenzo, A., Busciglio, J., et al. (1996). Apoptosis induced by HIV-1 infection of the central nervous system. Journal of Clinical Investigation, 98, 1979-1990.
24. Xu, Y., Kulkosky, J., Acheampong, E., Nunnari, G., Sullivan, J., & Pomerantz, R. J. (2004). HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy. Proceedings of the National Academy of Sciences USA, 101, 7070-7075.
25. Zhang, L., Shimizu, S., Sakamaki, K., Yonehara, S., & Tsujimoto, Y. (2004). A caspase-8-independent signaling pathway activated by Fas ligation leads to exposure of the Bak N-terminus. Journal of Biological Chemistry, 279, 33865-33874.