Silencing of monocarboxylate transporters via small interfering ribonucleic acid inhibits glycolysis and induces cell death in malignant glioma: An in vitro study

Neurosurgery

Volumn 55, Issue 6, 2004, Pages 1410-1419

  Mathupala, Saroj P ^a,c   Parajuli, Prahlad ^a   Sloan, Andrew E ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c KARMANOS CANCER INSTITUTE   (United States)

Author keywords

Lactate; Metabolism; Monocarboxylate transporters; Small interfering ribonucleic acid

Indexed keywords

LACTIC ACID; MONOCARBOXYLATE TRANSPORTER; SMALL INTERFERING RNA;

ACIDIFICATION; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; CELL DEATH; CELL METABOLISM; CELL PH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; EXPRESSION VECTOR; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; GLIOBLASTOMA; GLIOMA CELL; GLYCOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALIGNANT NEOPLASTIC DISEASE; MCT 1 GENE; MCT 2 GENE; MCT 3 GENE; MCT GENE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; RNA SEQUENCE; TUMOR NECROSIS; WESTERN BLOTTING;

APOPTOSIS; ASTROCYTOMA; BRAIN; BRAIN NEOPLASMS; CELL DEATH; CELL LINE, TUMOR; GLIOMA; GLYCOLYSIS; HUMANS; MEMBRANE TRANSPORT PROTEINS; MONOCARBOXYLIC ACID TRANSPORTERS; NECROSIS; PROTEIN ISOFORMS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 10044278250     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000143034.62913.59     Document Type: Article

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